Researching in test mouse. Result: In vivo, Honeysuckle flower have a acute anti-inflammatory effect when used alone as well as its combination with alpha-CT. In vitro, honeysuckle flower have a stimulate effect of the activity alpha-CT. The successful combination of decoction and honeysuckle flower (flavonoid) with alpha-CT(in vitro and in vivo) took a little part in studying the anti-inflammatory mechanism of honeysuckle flower with alpha-CT. The synergic effect of above two active element induced which give satisfactory anti-inflammatory effect, which was equivalent to some of modern medicine of use to anti-inflammatory drug.
Flowers ; Anti-Inflammatory Agents ; Flavonoids

In early 2004, following an epidemic of avian influenza A/H5N1 in human, an outbreak of influenza A/H3 occurred in 5 communes at Hung Yen province with 887 cases and no deaths. This outbreak developed quickly but only in medium geographical range (inter-commune). Most cases are of school-age (from 5 to 19 years old) which comprise over 85% of the total number and focus mainly in primary and secondary schools. Owing to discovered early the outbreak, consisted of determinate the reasons and response to outbreak quickly and strongly and applied routinely to prevention the spread through the respiratory, and it also the good lesson to the prevention of outbreak
Disease Outbreaks ; Influenza, Human ; epidemiology

Pseudomonas aeruginosa is resistant many antibiotics currently, including new generation, broad spectrum antibiotics that were very effective with other bacteria. Thus, it's difficult to treat P. aeruginosa infection with these antibiotics. Author collected P. aeruginosa strains from some hospitals in Hanoi, tested with more antibiotics in order to determine antibiotic resistant rate and types, to orient some mechanisms of antibiotic resistance of P. aeruginosa. Materials is 97 strains of P. aeruginosa isolated from blood and pus of patients treated at Bach Mai Hospital and National Institute of Burn from August 2002 to November 2003. Method: disk diffusion antibiotic sensitivity testing (Kirby - Bauer test). Results: Isolated P. aeruginosa strains are multiple antibiotic resistant (8 of 16 antibiotics), especially hospital infection strains are resistant 100% of tested antibiotics. It showed the potential roles of some enzymes such as penicillinase, cephalosporinase, AAC(6), ANT(2")-1, and ANT(2") enzymes that inhibit effects of antibiotics in bacterium cell
Anti-Bacterial Agents ; Pseudomonas aeruginosa ; Drug Resistance, Microbial

In the period from Aug 2002 to Aug 2003, at the National Institute of Burn strains of S. aureus and 45 strains of P.aeruginosa were isolated from the blood of severious septicemia patients.In disk diffusion test,100% of S.aureus strains were resistant to penicillin, erythromycine, kanamycine, tobramycine, gentamycine, oxacilline, 36% in particular, resistant to vancomycine and 45% to teicoplanine. 100%,of P.aeruginosa were resistant to ticarcilline, cefoperazol, gentamycine, tobramycine and 50% were resistant to ciprofloxacine.The most common effective combinations were rifampicine+acide fusidic, or rifampicine+ vancomycine for S. aureus, and imipenem + fosfomycine or imipenem+netilmycine, or imipenem +piperacillin/tazobactam for P.aeruginosa
Anti-Bacterial Agents ; Therapeutics ; Burns ; Infection

119 isolates of Shigella with multi-drug resistant (100 Shigella flexneri) to chloramphenicol (Cm), ampicillin (Ap), tetracyclin (Te), trimethoprim (Tr), sulfamethoxazole (Su) from Northern, Central and Southern regions of Viet Nam during a period of 1995-1997 were investigated for the ability to transfer gene trains by method of conjugation. 59.2% strains were transferable in vitro to E.coli K12 with frequence from 10-7 to 10-5 (65.8% strains from Northern, 54.8% strains from Central and 57.5% strains from Southern regions). Almost all the antibiotic resistance genes were transfered with 10 different patterns of resistance; Ap, Tr, Su being the most frequent patters: 45.7% strains fro Northern, 30.8% strains from Southern and 25.6% strains from Central regions.
Drug Resistance ; shigella

129 isolates of S.typhi multi-drug resistant to Cm, Ap, Te, Tr, Su from Northern, Southern and Central regions of Vietnam during 1995-1997 were examined to detect the ability to transfer gene encoding the resistance to antibiotics and to study molecular characters of it’s R-plasmids. Results indicated the presence of self-transferable plasmid in 90% S.typhi strains from Southern, and 100% strains from Northern and Central regions. These strains carried from 1 to 2 plasmids of molecular weighed 110 MD and 80 MD. Gene encoding the resistance to Cm, Ap, Te, Tr, and Su were found to be located on a large plasmid of 100 MD. All S.typhi strains from 3 regions showed to have large plasmids with identical molecular structure, this indicated the same origin of these S.typhi strains.
Drug resistance ; Salmonella typhi

126 multiply resistant S.typhi isolates were screened among 363 isolates collected from Northern, Central and Southern regions of Vietnam during the period 1995-1997. Transfer experiments of the resistance to E.coli K12-J53 from these S.typhi isolates were performed to determine their transferable capacity of resistance factors and its frequency. The results indicated that 74.78% of multiply resistant S.typhi isolates (AM, CL, TE, TR, SU) have R-factors, most of them contained all resistance genes characterizing the resistance of wild strains. The frequency of transfer of the resistance varied from 10-5 to 10-8.
Drug resistance ; Salmonella typhi

From 1/1991 to 5/1995, 43 arterio-venous malformations were operated on at the Dep of Neurosurgery of Viet Duc hospital- Ictus, neurological signs, disturbances of speech were the main presenting manifestations of this disease. CT Scanner angiogarphy and pathological examination were of paramount importance for the detection of this disease. Two procedures of treatment were utilised: surgical removal of the AVM and ventricular shunt. Post operative results were evaluted by repartition into 3 groups: - Good (clinical improvement): 95.3%. – Mean (with long lasting deficit): 2.35%.
Arteriovenous Malformations ; diagnosis ; surgery ; therapeutics

The studied was conducted to assess the health care demand and use primary health services in the communes of 10 provinces representing for 7 ecological areas countryside: Ninh Binh, Phu Tho, Bac Can, Quang Ninh, Quang Tri, Khanh Hoa, Dac Lac, Tay Ninh, Dong Thap, Can Tho. There are statistically significant differences of morbidity rate as well as health service use in genders, in ecological areas and in different economic levels. Morbidity rate in woman is higher than in men and the rate increases proportionally following older age. There are genders inequalities in using health services, especially among poor households. Women are more likely to seek self-treatment while men seeks higher quality of health care services in hospital. The different is statistically significant.
Health Services ; Women

In vitro, flavonoids from Lonicera japonica Thunb flavonoids stimulate the catalysis of hydrolysis starch. This stimulating effect depended on the concentration of Lonicera japonica flavonoid but their in vitro stimulations weren’t strong. The anti-inflammatory effects were stronger when combining flavonoid with -amylase on dextran-induced edema mouse legs. So active catalysis stimulation of -amylase could be associated with anti-inflammation process; with unclear mechanisms. This result suggested the need of further research of anti-inflammatory drugs according to combine of traditional medicine and anti-inflammatory enzyme
Flavonoids ; Anti-Inflammatory Agents ; Lonicera