The clinical and statistical evaluations of the 157 corneal grafted eyes which were operated at the Dept. of Ophthalmology, St. Mary's Hospital, Catholic Medical College from April, 1967 to May, 1978 were done. The fonow-up period ranged from 4 months to 11 years. The results were as follows: 1. Age incidence of corneal grafted patients was highest in the 20's and lowest in the age group under 10 years and over 50 years of age. 2. Male and female ratio was approximately 3:1. 3. The four major causes requiring corneal graft, the highest percentage wag occupied by trauma (38 eyes, 24.2%) followed by Herpes simplex keratitis(30 eyes, 19.1%), measles (24 eyes, 15.3%) and phlyctenular keratitis(15 eyes, 9.6%). At the time of keratoplasty, the cnndition of the majority of the cornea were either Leucoma cornea (77 eyes, 49.0%) or Leucoma cnrnea adherens (38 eyes, 24.2%). 4. One hundred and fourty-two eyes(90.4%) had penetrating keratoplasty operations and 15 eyeg(9.6%) lamellar grafts. 5. Eighty five point four percentage of ths total grafted eyes maintained clarity of grafted cornea. 6. The causes of the 23 opaque grafts were graft rejection (l4 eyes, 60.9 %), recurrence of the Herpes simplex keratitis(2 eyes, 8.7%), neovascularization of the donor cornea(2 eyes, 8.7%) and others(5 eyes, 21.7%). 7. Five eyes had penetrating keratoplasty and cataract operation simultaneously. Four eyes retained clarity of the cornea with improvement of visual acuity: however, one eye was unsuccessful due to vitreous body touching the corneal endothelium. 8. Post-operative visual improvement was seen in 118 eyes (75.2%). Useful vision (F.C. -0.4) was obtained in 84 eyes (71.8%) among 118 eyes. Twenty-four eyes improved to vigual acuity of greater than 0.4 while 9 eyes improved to less than F.C. (finger count).
Cataract ; Cornea ; Corneal Transplantation ; Endothelium, Corneal ; Female ; Graft Rejection ; Herpes Simplex ; Humans ; Incidence ; Keratoplasty, Penetrating ; Male ; Measles ; Ophthalmology ; Recurrence ; Tissue Donors ; Transplants* ; Visual Acuity ; Vitreous Body

The authors experienced a case of persistent pupillary membrane of both eyes whose left eye was required an optical irridectomy operation. The patient was a 2 years old Korean girl who visited our hospital because of visual disturbanc of left eye and Conitant exotropia and abnormally looking pupils of the both eyes. Her visual acuity of left eye was so poor that She couldn't walk around when her right eye was occuluded. Because of the complete peasistent pupillary membrane of left eye, optical irridectomy was peformed. Visual acuity of her left eye postoperatively performed.
Child, Preschool ; Exotropia ; Female ; Humans ; Membranes* ; Pupil ; Visual Acuity

Authors performed a Binkhorst iris clip lens implantation after intracapsular cryoextraction in a senile cataract patient, aged 76, male. In this both eye cataract patient, only right eye was received a successful implantation of intraocular lens (Binkhorst iris clip lens) under operating microscopy. There was no complication during and after operation. Until one year after operation no complication was found, and corrected vision was normal (20/20).
Cataract ; Humans ; Iris* ; Lenses, Intraocular ; Male ; Microscopy

Marfan's Syndrome was a collagenous hereditary disorder affected by the long bone, heart and eyes. This typical arachnodactyly patient was 8 year old boy who has had visual disturbance due to central opacitous lens subluxation of both eyes. We performed successfull intracapsular lens extraction by use of cryolens extractor for both eyes. X-ray chest suggested the evidence of aortic aneurysm. Electron microscopic study for the zonular fibers of the lens showed a relative loose aggregated zonular fibers with small amount of its bundles, but chromosomal study for this patient showed no abnormality.
Aortic Aneurysm ; Arachnodactyly ; Child ; Collagen ; Heart ; Humans ; Lens Subluxation ; Male ; Marfan Syndrome ; Thorax

Pancreatic islet transplantation is a physiologically advantageous and minimally invasive procedure for the treatment of type 1 diabetes mellitus. Here, we describe the first reported case of successful allogeneic islet transplantation alone, using single-donor, marginal-dose islets in a Korean patient. A 59-yr-old patient with type 1 diabetes mellitus, who suffered from recurrent severe hypoglycemia, received 4,163 islet equivalents/kg from a single brain-death donor. Isolated islets were infused intraportally without any complications. The immunosuppressive regimen was based on the Edmonton protocol, but the maintenance dosage was reduced because of mucositis and leukopenia. Although insulin independence was not achieved, the patient showed stabilized blood glucose concentration, reduced insulin dosage and reversal of hypoglycemic unawareness, even with marginal dose of islets and reduced immunosuppressant. Islet transplantation may successfully improve endogenous insulin production and glycemic stability in subjects with type 1 diabetes mellitus.
Blood Glucose/analysis ; Diabetes Mellitus, Type 1/*surgery ; Female ; Humans ; Hypoglycemia/*surgery ; Immunosuppression/methods ; Immunosuppressive Agents/therapeutic use ; Islets of Langerhans/physiology/*surgery ; Islets of Langerhans Transplantation/*methods ; Middle Aged ; Republic of Korea ; Tissue Donors