No abstract available.

No abstract available.

No abstract available.
Heart Septal Defects, Ventricular* ; Pulmonary Artery* ; Pulmonary Atresia*

PURPOSE: We evaluated the effectiveness and safety of ipsilateral radiotherapy for the patient with well lateralized tonsil cancer: not cross midline and <1 cm of tumor invasion into the soft palate or base of tongue. MATERIALS AND METHODS: From 2003 to 2011, twenty patients with well lateralized tonsil cancer underwent ipsilateral radiotherapy. Nineteen patients had T1-T2 tumors, and one patient had T3 tumor; twelve patients had N0-N2a disease and eight patients had N2b disease. Primary surgery followed by radiotherapy was performed in fourteen patients: four of these patients received chemotherapy. Four patients underwent induction chemotherapy followed by concurrent chemoradiotherapy (CCRT). The remaining two patients received induction chemotherapy followed by radiotherapy and definitive CCRT, respectively. No patient underwent radiotherapy alone. We analyzed the pattern of failure and complications. RESULTS: The median follow-up time was 64 months (range, 11 to 106 months) for surviving patients. One patient had local failure at tumor bed. There was no regional failure in contralateral neck, even in N2b disease. At five-year, local progression-free survival, distant metastasis-free survival, and progression-free survival rates were 95%, 100%, and 95%, respectively. One patient with treatment failure died, and the five-year overall survival rate was 95%. Radiation Therapy Oncology Group grade 2 xerostomia was found in one patient at least 6 months after the completion of radiotherapy. CONCLUSION: Ipsilateral radiotherapy is a reasonable treatment option for well lateralized tonsil cancer. Low rate of chronic xerostomia can be expected by sparing contralateral major salivary glands.
Chemoradiotherapy ; Disease-Free Survival ; Follow-Up Studies ; Humans ; Induction Chemotherapy ; Neck ; Palate, Soft ; Palatine Tonsil ; Recurrence ; Salivary Glands ; Survival Rate ; Tonsillar Neoplasms ; Treatment Failure ; Xerostomia

Class III malocclusions are difficult to treat and take more time than any other types. But if such problems are detected at the earliest opportunity, we may gain the best possible correction consistent with the limitations imposed by morphogenetic pattern. The question of whether a patient has false or real Class III malocclusion is not important. Therapy wilt eleminate the malrelationship, in any event. Graber said, "It has been my experience that many so-called "pseudo" Class III"s are full-blown Class III" s later on during the prolific growth period." The authors have attempted early treatment of a Class III malocclusion of 8-year old girl, who has the familial history of Class III malocclusion.
Child ; Female ; Humans ; Malocclusion*

No abstract available.
Functional Laterality*

The present study was designed to obtain omparative data on in vitro antifungal activities of imidazole derivatives. Minimum inhibitory oncentrations of clotrimazole, miconazole, econazole, ketoconazlole and griseofulvin on 4 strains of Trichophyton mentagrophytes, 3 strains of Trichophyton rubrum, 2 strains of Microsporum canis and ] strain of Sporothriv: schenckii were etermined after 3 week' incubation at room temperature on Sabouraud's dextrose liquid media. In addition, the fungicidal activities of miconazole and econazole were tested against Z'richophyton mentagrophytes and Microsporum canis, using the techniques described by Vanbreuseghern(1967) The results are summarzed as follows: ] In most of the dermatophytes studied, 1 to 10 pg/ml of M1C were detected. Diverse susceptibility pattern was observed among different fungal species, but no or minor variability was noted within the same species. The susceptibility of Z'ri- chophyton rubrum showed at MIC of 0. 01 to 10 pg/ml, T ichophyton mentagro- phyt.es and Mic osporum canis at 0.1 to 10 pg/ml and 0. 1 to 1000 gg/ml respec- tively. The Trichophyton rubrum was the most sensitive. In the susceptibility test of Sporothrix schenckii, the high resistance to clotrimazole and griseofuhin was observed. The fungistatic activities of miconazole, econazole and ketoconazole were observed only at concentrations higher than JpQ pg/ml.
Arthrodermataceae ; Clotrimazole ; Econazole ; Glucose ; Griseofulvin ; Ketoconazole ; Miconazole ; Microsporum ; Sporothrix ; Trichophyton

The authors observed 2 cases of poikilcdermatomyositis who were 16 and l0 years old female. The former visited our dept. due to rashes on the anterior portion of right thigh with 3 months duration. The skin lesion revealed mottled skin pigmentation, telangiectasia, atrophy, and cigarrette paper like wrinklings. On the palpation, hardness and tenderness in the lesion were felt. The latter visited our dept. due to weakness of the right lower extremity for 3years. The skin lesion revealed the same feature as the former but more prominent. Histophthologically, P.V.A. patterns are seen in the both skin lesions. The epidermis shows moderate atrophy of St. malphigi and flattening of reteridges. The dermis is edematous, vascular dilatations, and cellular infiltrations, most of lymphocytes, around the blood vessels. The muscle biopsies for the Quardriceps Femoris sbow Dermatomyositis patterns which the muscle bundles are degenerative changes and many cellular infiltrations, chiefly of lymphocytes, are seen between the muscle bundles. Diagnosis was confirmed by the clinical and histological pictures. These patients were markedly improved by the prednisolone therapy.
Atrophy ; Biopsy ; Blood Vessels ; Dermatomyositis ; Dermis ; Diagnosis ; Dilatation ; Epidermis ; Exanthema ; Female ; Hardness ; Humans ; Lower Extremity ; Lymphocytes ; Palpation ; Prednisolone ; Skin ; Skin Pigmentation ; Telangiectasis ; Thigh

No abstract available.

PURPOSE: Hemolytic uremic syndrome is one of the most frequent cause of acute renal failure in children and can lead to progressive deterioration of renal function. Present nationwide study was undertaken to determine the clinical characteristcs and prognostic factors of hemolytic uremic syndrome in korean children during past 10 years(1990-1999). METHODS: Questionnaires(including clinical data, prodromal illness, lab data, treatment modality and prognosis) were mailed to all teaching hospitals in korea and 27 hospitals responded. During past 10 years, total 149 cases of HUS were diagnosed. Statistical analysis was done by chi-square test, using p<0.05 being "statistically significant". RESULTS: Sex distribution showed slight female preponderance(female 84 vs male 65 cases) and "under 5 years of age" comprised 71.8%(107 cases). Yearly distribution showed increasing number of HUS cases during past 3-4 years and the majority of cases occurred during summer months. Diarrhea was the most common prodromal illness comprising 75.2 % followed by URI 18.2% and in 3.5% of cases no prodromal illness was noted. Lab data (mean+/-SD) showed Hb 7.3+/-2.1g/dL, platelet 49+/-32 X 103cells/mm3, BUN 74+/-36mg/dL, and creatinine 3.7+/-2.8mg/dL. Hypertension was seen in 32.9%, convulsion in 16.7%, mental change in 15.4% and renal replacement therapy(PD or HD) was done in 49.7% of cases. Clinical outcome showed complete recovery in 75.5%, persisting abnormal urinalysis without renal failure in 11.1%, chronic renal failure(including ESRD) in 6.7% and death in 6.7%(9 cases). Poor prognosis was associated with older patients age, higher serum creatinine level, existence of mental change and longer duration of oligoanuria. Out of these, duration of oligoanuria was the most closely associated factor leading to poor outcome. Out of 119 cases with "oligoanuria under 2 weeks", CRF and death were seen in 2 and 7 cases respectively. Compared to this, out of 12 cases with "oligoanuria over 2 weeks", CRF and death were seen in 4 and 2 cases respectively(p<0.0005). CONCLUSION: The incidence of HUS is increasing recently in Korean children. And out of various prognostic factors(older age, higher serum creatinine, existence of mental change and duration of oligoanuria), duration of oligoanuria was the most significantly associated factor leading to poor outcome.
Acute Kidney Injury ; Blood Platelets ; Child* ; Creatinine ; Diarrhea ; Female ; Hemolytic-Uremic Syndrome* ; Hospitals, Teaching ; Humans ; Hypertension ; Incidence ; Korea ; Male ; Postal Service ; Prognosis ; Renal Insufficiency ; Seizures ; Sex Distribution ; Urinalysis