A 34-year-old Korean man presented with a 3 week history of a yellowish eczema like patch on the left thigh. Sixteen months prior, he was diagnosed with polymorphie r eticulosis of the left nasal cavity. The patient, refuse<3 conventional radiation therapy and took herbal medication and diet therapy instead. Biopsy of the nasal cavity, hard palate and left thigh lesians showed extensive necrosis and polymorphic infiltrates of atypical lymphocytes with angiodestructive invasion. Irnmunohistochemical study of left thiyh lesion showed strong CD2 positivity con sistent with the diagnosis of peripheral T cell lymphorra.
Adult ; Biopsy ; Diagnosis ; Diet Therapy ; Eczema ; Humans ; Lymphocytes ; Lymphoma, T-Cell, Peripheral ; Nasal Cavity ; Necrosis ; Palate, Hard ; Skin* ; Thigh

No abstract available.
Chorion* ; Chorionic Villi*

No abstract available.
Diagnosis* ; Middle Lobe Syndrome* ; Thorax*

Histiocytosis-X is a term used to define three diseases with similar morphologic characteristics : Letterer-Siwe diseae, Hand-Schuller-Christian disease and Eosinophilic granuloma. In general, they differ in terms of their age of onset, severity of clinical course and site of involvement. Eosinophilic granuloma typically is seen in young adults. Eosinophilic granuloma is diagnosed in the presense of diffuse pulmonary infiltrate, bony involvement. However, the Pulmonary radiologic findings of eosinophilic granuloma are variable accordinary to stage of disease. therefore pathologic diagnosis of involving site is essential for confirmative diagnosis of eosinophilic grananuloma. Pathologically. the three disease are characterized by granulomatous infiltration of alveolar septa and bronchial walls and often involvement of bone. The hallmark of this disease is proliferation of the Langerhans' cell. The identifying feature is the X-body or Birbeck granule that is present in Langerhans' cells and histiocytic cells found in the lung of EG patient. We report a case of bilateral, recurrent and spontaneous pneumothoraces in a 21 year old man with pulmonary histiocytosis-X which is confined by eosinophilc granuloma in bone marrow biopsy and ultrastructural examination in cells obtained from BAL.
Age of Onset ; Biopsy ; Bone Marrow ; Diagnosis ; Eosinophilic Granuloma ; Eosinophils ; Granuloma ; Histiocytosis, Langerhans-Cell* ; Humans ; Lung ; Pneumothorax* ; Young Adult

OBJECTIVE: To determine the feasibility and safety of performing laparoscopically assisted vaginal hysterectomy (LAVH) for uteri weighing 500 g or more and evaluate the advantages and complications of LAVH. METHODS: A subpopulation of 30 women with uteri weighing 500 g or more from group of 412 patients undergoing LAVH between Mar, 2003 to Feb, 2005. We reviewed medical records and analyzed these cases about age, parity, history of previous abdominal surgery, preoperative indications, postoperative pathologic diagnosis, mean operation times, weight of extracted uterus, change of hemoglobin, hospital stay, and complications. RESULTS: The mean age was 44.8+/-3.88 years. The mean parity was 1.78+/-0.76. Previous operation history was 16 cases (53.3%). The most common indication of operation was palpable abdominal mass. The most common pathologic diagnosis was leiomyoma. The mean operation time was 126.40+/-39.30 minutes. The mean weight of uterus was 621.23+/-107.28 g. The mean hemoglobin change was 1.57+/-1.14 g/dL. The mean hospital stay was 3.74+/-0.88 days. The only complication of operation was superficial trocar site bleeding (1 case). CONCLUSION: LAVH is a safe and effective alternative to total abdominal hysterectomy of the uteri weighing 500 g or more in selective groups.
Diagnosis ; Female ; Hemorrhage ; Humans ; Hysterectomy ; Hysterectomy, Vaginal* ; Leiomyoma ; Length of Stay ; Medical Records ; Parity ; Surgical Instruments ; Uterus*

BACKGROUND: Dermatofihromas are relatively common benign tumors which occur in the skin. However, clinical and histopathological studies have been rarely reported in Korea. OBJECTIVE: This study was taken to evaluate the clinical and histopathological features of dermatofibromas in Korea. METHODS: Fifty cases of dermatofibromas were selected from 10 years of laboratory files for during the period January 1985 to December 1994 at Chung Ang University Hospitals. RESULTS: 1. The age range was from 18 to 61 and the average age at diagnosis was 38.7(male;37.6, female;39.4). The ratio of male to female was 1.0: 16(19:31). 2. The diameter of the dermatofibromas : 1) 5-20mm;32 cases(64.0%), 2) 5mm>;8 cases(16.0 %), 3) 20mm<;7 cases(14.0%), 4) unrecorded;3 cases(6.0%). 3. The most common color was brown(14 cases, 28.0% ), and other common colors were skin-color(7 cases, 14.0%), red(4 cases, 8.0%), black(3 cases, 6.0%), violaceous(2 cases, 4.0%), unknown(20 cases, 40.0%). 4. Thirty seven cases(74.0%) had solitary lesions, and thirteen cases(26.0%) had multiple lesions. 5. The lower extremeties(39 cases, 50.6%) were the most common sites followed by the back (10 cases, 13.0%), upper extremities(9 cases, 11.7%), shoulders(8 cases, 10.4%), abdomen(4 cases, 5.2%), hands(2cases, 2.6%), face(2 cases, 2.6%), neck(2 cases, 2.6%), breast(1 case, 1.3%). 6 Histopathologically, fibrous types were seen in 40 cases(80.0%), cellular types in 3 cases(6.0 %), mixed types in 5 cases(10.0%), and sclerosing hemangiomas in 2 cases(4.0%). CONCLUSION: The 50 cases of dermatofibromas, which were confirmed at Chung Ang University Hospitals from January 1985 to December 1994, were reviewed clinically and histopathologically.
Diagnosis ; Female ; Histiocytoma, Benign Fibrous* ; Hospitals, University ; Humans ; Korea ; Male ; Skin

No abstract available.
Thorax*

Hypertensive pontine hemorrhage usually causes profound, irreversible neurological deficits, with ominous prognosis, and is often fatal. There is controversy as to the appropriate treatment modality, but in general, surgical intervention is considered unethical. The authors report the outcome of hypertensive pontine hemorrhage in 13 patients whose Glasgow Coma Scale was 4-9, who on brain CT scan were seen to have over 10cc of hematoma and who underwent suboccipital craniectomy for hematoma removal. These patients could be divided in two groups: 'early'(9 patients), who underwent surgery within 24 hours of ictus, and 'late'(4 patients), who underwent surgery 6 to 20 days after ictus: all had shown neurological deterioration in spite of optimal medical treatment. Surgical outcome did not vary according to the extent of hematoma removal. For patients in the 'early' group, surgery was not useful, but three in the 'late' group, the GCS score improved to between 7 and 11. This study suggests that in hypertensive pontine hemorrhage, an early direct approach may not improve outcome, but for selected patients, who deteriorate during conservative treatment, surgery may be beneficial.
Brain ; Glasgow Coma Scale ; Hematoma ; Hemorrhage* ; Humans ; Prognosis ; Tomography, X-Ray Computed

Cheilitis granulomatosa is a rare disorder of uncertain etiology and characterized by a recurrent orofacial swelling, which was described by Miescher in 1945 for the first time. Symptoms usually manifest during adolescence and initially transient, but subsequently a chronic progressive disability develops. No efficient mode of therapy is yet available. A 71-year-old woman presented with a prominent upper lip swelling which had persisted for more than 6 years. There were no fissuring of the tongue and facial palsy. Oral prednisone was instituted for 6 months with moderate clinical improvement. 2 years later, multiple biopsies were performed at the hard palate, gingiva, and inferior turbinate. And the specimens from the gingiva and inferior turbinate showed scattered non-caseating granulomas, consistent with 'Cheilitis Granulomatosa'. We present here our experience with long-term trial of oral corticosteroid in a 71-year-old woman with cheilitis granulomatosa who had suffered recurrent labial swelling.
Adolescent ; Aged ; Biopsy ; Cheilitis* ; Facial Paralysis ; Female ; Gingiva ; Granuloma ; Humans ; Lip ; Melkersson-Rosenthal Syndrome* ; Palate, Hard ; Prednisone ; Tongue ; Turbinates

No abstract available.
Liver Transplantation* ; Liver*