A 34-year-old Korean man presented with a 3 week history of a yellowish eczema like patch on the left thigh. Sixteen months prior, he was diagnosed with polymorphie r eticulosis of the left nasal cavity. The patient, refuse<3 conventional radiation therapy and took herbal medication and diet therapy instead. Biopsy of the nasal cavity, hard palate and left thigh lesians showed extensive necrosis and polymorphic infiltrates of atypical lymphocytes with angiodestructive invasion. Irnmunohistochemical study of left thiyh lesion showed strong CD2 positivity con sistent with the diagnosis of peripheral T cell lymphorra.
Adult ; Biopsy ; Diagnosis ; Diet Therapy ; Eczema ; Humans ; Lymphocytes ; Lymphoma, T-Cell, Peripheral ; Nasal Cavity ; Necrosis ; Palate, Hard ; Skin* ; Thigh

No abstract available.
Chorion* ; Chorionic Villi*

No abstract available.
Diagnosis* ; Middle Lobe Syndrome* ; Thorax*

Histiocytosis-X is a term used to define three diseases with similar morphologic characteristics : Letterer-Siwe diseae, Hand-Schuller-Christian disease and Eosinophilic granuloma. In general, they differ in terms of their age of onset, severity of clinical course and site of involvement. Eosinophilic granuloma typically is seen in young adults. Eosinophilic granuloma is diagnosed in the presense of diffuse pulmonary infiltrate, bony involvement. However, the Pulmonary radiologic findings of eosinophilic granuloma are variable accordinary to stage of disease. therefore pathologic diagnosis of involving site is essential for confirmative diagnosis of eosinophilic grananuloma. Pathologically. the three disease are characterized by granulomatous infiltration of alveolar septa and bronchial walls and often involvement of bone. The hallmark of this disease is proliferation of the Langerhans' cell. The identifying feature is the X-body or Birbeck granule that is present in Langerhans' cells and histiocytic cells found in the lung of EG patient. We report a case of bilateral, recurrent and spontaneous pneumothoraces in a 21 year old man with pulmonary histiocytosis-X which is confined by eosinophilc granuloma in bone marrow biopsy and ultrastructural examination in cells obtained from BAL.
Age of Onset ; Biopsy ; Bone Marrow ; Diagnosis ; Eosinophilic Granuloma ; Eosinophils ; Granuloma ; Histiocytosis, Langerhans-Cell* ; Humans ; Lung ; Pneumothorax* ; Young Adult

OBJECTIVE: To determine the feasibility and safety of performing laparoscopically assisted vaginal hysterectomy (LAVH) for uteri weighing 500 g or more and evaluate the advantages and complications of LAVH. METHODS: A subpopulation of 30 women with uteri weighing 500 g or more from group of 412 patients undergoing LAVH between Mar, 2003 to Feb, 2005. We reviewed medical records and analyzed these cases about age, parity, history of previous abdominal surgery, preoperative indications, postoperative pathologic diagnosis, mean operation times, weight of extracted uterus, change of hemoglobin, hospital stay, and complications. RESULTS: The mean age was 44.8+/-3.88 years. The mean parity was 1.78+/-0.76. Previous operation history was 16 cases (53.3%). The most common indication of operation was palpable abdominal mass. The most common pathologic diagnosis was leiomyoma. The mean operation time was 126.40+/-39.30 minutes. The mean weight of uterus was 621.23+/-107.28 g. The mean hemoglobin change was 1.57+/-1.14 g/dL. The mean hospital stay was 3.74+/-0.88 days. The only complication of operation was superficial trocar site bleeding (1 case). CONCLUSION: LAVH is a safe and effective alternative to total abdominal hysterectomy of the uteri weighing 500 g or more in selective groups.
Diagnosis ; Female ; Hemorrhage ; Humans ; Hysterectomy ; Hysterectomy, Vaginal* ; Leiomyoma ; Length of Stay ; Medical Records ; Parity ; Surgical Instruments ; Uterus*

Relapsing polychondritis is a rare systemic disorder manifested by recurring episodes of inflammation in cartilagenous tissues including the eye, the audiovascular and cardiovascular systems. We describe a 53-year-old oriental woman with a one month history of painful swelling of both ears accompanied by intermittent hoarseness, dyspnea, impaired visual acuity, and swelling of hands. Both ear lobes were typically uninvolved. Auricle including cartilaginous tissues were histologically examined, which revealed loss of basophilic staining, degenerative changes, inflammatory cells infiltrations with eosinophils and neutrophils, and perichondrial inflammation of the cartilage. Oral prednisolone and colchicine were prescribed and the successful resolution of both ears swelling were observed. As the disease progressed optic neuritis and chewing difficulty by non-erosive motion limit of temporo-mandibular joints developed.
Basophils ; Cardiovascular System ; Cartilage ; Colchicine ; Dyspnea ; Ear ; Eosinophils ; Female ; Hand ; Hoarseness ; Humans ; Inflammation ; Joints ; Mastication ; Middle Aged ; Neutrophils ; Optic Neuritis* ; Polychondritis, Relapsing* ; Prednisolone ; Visual Acuity

According to Moertel's classification, synchronous multiple gastric cancer is eonsidered to be a sort of multiple primary cancer, The clinical signifieance of multiplicity in gastric cancer was its location relative to the resection line. Compared with patients with single gastric cancer, multiple gastric cancer were more frequently found among the older men, and they were more commonly found in early gastric cancer. The frequency of multifocality in gastric cancer is 2.2-9% in the world literature reports and is increasing recently, with advance in the diagnostic method of gastric cancer. However, synchronous multiple gastric cancer which has more than four foci is rare. In Korea, there has been only one case reported about quadruple gaatric cancer. Recently, we experienced a case of a 58-year-old male patient with synchronously developed-quadruple gastric cancer on the body of stomach, for whom radical total gastrectomy and esophagojejunostomy was done. All of them were moderately differentiated adenocarcinoma. The mapping about four lesions showed that Borrmanin type III AGC extending to the serosa was placed on the posterior wall of higher body; EGC IIc invading the submucosa, the anterior wall of mid body, EGC III confined to the mucosa, the lesser curvature side of mid to lower body; EGC III localizing to the mucosa, the posterior wall of lower body. So we reported this case with a review of literatures.
Adenocarcinoma ; Classification ; Gastrectomy ; Humans ; Korea ; Male ; Middle Aged ; Mucous Membrane ; Serous Membrane ; Stomach ; Stomach Neoplasms*

BACKGROUND: Surgical intervention is known as the principle management for hemoptysis of significant amount But surgical procedure is applicable 13 only small number of patients because of increased mortality in emergency surgery and various functional and structural problems after lung resection. Bronchial artery embolization(BAE) has been used as an alternative interventional technique for immediate control of patients with increased risk for surgery due 19 recurrent or massive hemoptysis. BAE also has limitations such as recurrent bleeding after procedure and its role for the application to small amount of hemoptysis is still not established. METHOD: To evaluate immediate and long term effectiveness of BAE, we analysed 65 patients with hemoptysis according to therapeutic modalities they received ; BAE versus conservative management. RESULTS: The success rate for immediate control of hemoptysis was significantly higher in BAE group with 43 cases(100%) among 43 cases compared with 17 cases(77%) among 22 cases in conservative group (p<0.001). The disease control duration was 19.5α8.06 months in BAE group and 18.8α6.06 months in conservative group(p>0.05). The therapeutic response in BAE group was 82%(36/43 cases) and 95%(21/22 cases) in conservative group(p>0.05). According to the amount of hemoptysis, the therapeutic response were seen in 91%(29/32 cases) in less than 100ml and 85%(28/33 cases) in 100~400ml (p>0.05). According to the manifestation of hemoptysis, the therapeutic response in groups of recurrent and nonrecurent were 87%(20/23 cases) and 88%(37/42 cases)(p>0.05). CONCLUSION: The difference of therapeutic response between BAE and conservative group in patients with small amounts of hemoptysis was not found except for immediate control of hemoptysis.
Bronchial Arteries* ; Emergencies ; Hemoptysis* ; Hemorrhage ; Humans ; Lung ; Mortality

BACKGROUND: Dermatofihromas are relatively common benign tumors which occur in the skin. However, clinical and histopathological studies have been rarely reported in Korea. OBJECTIVE: This study was taken to evaluate the clinical and histopathological features of dermatofibromas in Korea. METHODS: Fifty cases of dermatofibromas were selected from 10 years of laboratory files for during the period January 1985 to December 1994 at Chung Ang University Hospitals. RESULTS: 1. The age range was from 18 to 61 and the average age at diagnosis was 38.7(male;37.6, female;39.4). The ratio of male to female was 1.0: 16(19:31). 2. The diameter of the dermatofibromas : 1) 5-20mm;32 cases(64.0%), 2) 5mm>;8 cases(16.0 %), 3) 20mm<;7 cases(14.0%), 4) unrecorded;3 cases(6.0%). 3. The most common color was brown(14 cases, 28.0% ), and other common colors were skin-color(7 cases, 14.0%), red(4 cases, 8.0%), black(3 cases, 6.0%), violaceous(2 cases, 4.0%), unknown(20 cases, 40.0%). 4. Thirty seven cases(74.0%) had solitary lesions, and thirteen cases(26.0%) had multiple lesions. 5. The lower extremeties(39 cases, 50.6%) were the most common sites followed by the back (10 cases, 13.0%), upper extremities(9 cases, 11.7%), shoulders(8 cases, 10.4%), abdomen(4 cases, 5.2%), hands(2cases, 2.6%), face(2 cases, 2.6%), neck(2 cases, 2.6%), breast(1 case, 1.3%). 6 Histopathologically, fibrous types were seen in 40 cases(80.0%), cellular types in 3 cases(6.0 %), mixed types in 5 cases(10.0%), and sclerosing hemangiomas in 2 cases(4.0%). CONCLUSION: The 50 cases of dermatofibromas, which were confirmed at Chung Ang University Hospitals from January 1985 to December 1994, were reviewed clinically and histopathologically.
Diagnosis ; Female ; Histiocytoma, Benign Fibrous* ; Hospitals, University ; Humans ; Korea ; Male ; Skin

Microcystic adnexal carcinoma(MAC) is an unusual carcinoma of eccrine glands, composed of pilar and sweat duct structures. We report here a 64-year-old man with MAC on his left cutaneous upper lip. Microscopically, the tumor consisted of nests and gland-like structures within desmoplastic stroma, and it stained positively for carcinoembryonic antigen. The clinical appearance and histopathologic findings of the tumor may be mistaken for other benign and malignant entities. The patient was treated with excision and skin flap, and no recurrence over a 31-month follow up period.
Carcinoembryonic Antigen ; Eccrine Glands ; Follow-Up Studies ; Humans ; Lip ; Middle Aged ; Recurrence ; Skin ; Sweat