1.Effects of Intraoperative Injection of Tarasyn for Pain Relief on Patients Undergoing Hemorrhoidectomy: Result of a prospective, randomized trial.
Journal of the Korean Society of Coloproctology 2000;16(6):371-375
PURPOSE: The aim of this prospective study was to evaluate whether additional intraoperative injection of Tarasyn (ketorolac tromethamine) provided a preemptive analgesic effect that improved postoperative pain. METHODS: Sixty patients scheduled for hemorrhoidectomy were randomly assigned to the study and control groups. For the control group (n=32), patients were treated with standard intravenous injections of Nubain (Nalbuphine hydrochloride; Jeil Pharmaceuticals Co, Seoul) per 8 hours for three times postoperatively for pain relief. In the study group (Tarasyn group, n=28), 60 mg of Tarasyn (ketorolac tromethamine; Roche Korea, Seoul) was injected into the internal sphincter muscle and around the operative wound at the time of hemorrhoidectomy as well as standard intravenous injections of Nubain . Parameters were measured of pain score from 0 (no pain) to 10 (agonizing pain), painless sound sleep, additional analgesic requirements, time to first bowel movement, and postoperative urinary retention. RESULTS: Rate of painless sound sleep was 75.0% and 53.1% in the Tarasyn and the control groups, respectively, which was significant statically between two groups (P<0.05). Time to first bowel movement was 2 and 3.2 days in Tarasyn and the control groups, respectively, which was also significant statistically (P<0.05). Voiding difficulty developed in one case (3.5%) in the Tarasyn group and he needed catheterization. In the control group, however, the number (15 cases, 46.9%; P<0.001) was much higher requiring more catherization (13 cases, 40.9%; P<0.001). Mean pain scores was significant statically between two groups (P<0.001). CONCLUSION: The data suggest that the use of intraoperative injection of Tarasyn is associated with a significant decrease in pain and urinary complications after hemorrhoidectomy.
Catheterization
;
Catheters
;
Hemorrhoidectomy*
;
Humans
;
Injections, Intravenous
;
Korea
;
Nalbuphine
;
Pain, Postoperative
;
Prospective Studies*
;
Tromethamine
;
Urinary Retention
;
Wounds and Injuries
2.Surgical treatment of periampullary cancer.
Sang Soon KIM ; Hong Jo CHOI ; Ik Ryong LEE
Journal of the Korean Cancer Association 1993;25(6):878-887
No abstract available.
3.Left pulmonary artery agenesis: one case report.
Yong Hwan KIM ; Keon Hyon JO ; Moon Sub KWACK ; Se Wha KIM ; Hong Kyun LEE
The Korean Journal of Thoracic and Cardiovascular Surgery 1991;24(1):83-87
No abstract available.
Pulmonary Artery*
4.Congenital Giant Pigmented Nevus with Malignant Melanoma of Brain.
Dong Hoon SHIN ; Hyun Suk KIM ; Jong Soo CHOI ; Ki Hong KIM ; Soo Ho JO
Korean Journal of Dermatology 1989;27(6):772-776
We report a case of congenital giant pigmented nevus with malignant melanoma of brain in a 14-year-old male patient. He had giant pigmented nevus on the back and neck, and multiple satellite lesions over the whole body since birth. One year prior to visit to our hospital, the patient suffered from various neurologie symptoms including headache, nausea, vomiting, seizure and right side motor weakness. Flistologic findings of skin lesions were benign nevocytic nevi. Computed tomogram of brain demonstrated increased densities in the both fronto-parietal leptameninges and brain parenchyme. Histologic findings of brain parenchyme by stereotaxic long needle biopsy showed the infiltration of melanin containing atypical melanocytes. There was no evidence of malignant melanoma at other organs. All of these findings suggested that origin of malignant melanoma of brain parenchyme was leptomeninges rather than skin.
Adolescent
;
Biopsy, Needle
;
Brain*
;
Headache
;
Humans
;
Male
;
Melanins
;
Melanocytes
;
Melanoma*
;
Nausea
;
Neck
;
Nevus
;
Nevus, Pigmented*
;
Parturition
;
Seizures
;
Skin
;
Vomiting
5.A Case of Spontaneous Retroperitoneal Hemorrhage due to Iliopsoas Muscle Hematoma in Patient with Myocardial Infarction Receiving Intravenous Heparin.
Hyo Jeong KIM ; Do Yeon KIM ; Min Gyu WHANG ; Hong Kun JO
Korean Circulation Journal 1998;28(10):1798-1801
The most common adverse effect of intravenous heparin is hemorrhage. Of the these, retroperitoneal hemorrhage and femoral neuropathy secondary to heparin anticoagulation has reported in 1966 for the first time by DeBolt and Jordan. We experienced a case of spontaneous retroperitoneal hemorrhage due to iliopsoas muscle hematoma in patient with myocardial infarction receiving intravenous heparin for a 3 days in therapeutic doses. The pathophysiology of iliopsoas muscle hematoma has not yet been cleared. But because of the possibility of large amount in volume, retroperitoneal hemorrhage has been known as a serious adverse effect that leads to the hypovolemic shock and death. In this article, we described the clinical manifestation, the importance of the early diagnosis and diagnostic clues and associated factors of the retroperitoneal hemorrhage in patient receiving intravenous heparin.
Early Diagnosis
;
Femoral Neuropathy
;
Hematoma*
;
Hemorrhage*
;
Heparin*
;
Humans
;
Jordan
;
Myocardial Infarction*
;
Shock
6.A case of Colorectal carcinoma During Pregnancy.
Mi Yeong JO ; Ki Hong CHANG ; Haeng Soo KIM ; Kie Suk OH
Korean Journal of Obstetrics and Gynecology 2000;43(5):901-904
Colorectal cancer during pregnancy is rare but the trend for women to delay pregnancy until later in life may result in increased incidence of colorectal cancer during pregnancy. The most common symptoms are rectal bleeding, abdominal discomfort, abdominal distension, anorexia, nausea, vomiting, constipation, anemia and weight loss. Rectal bleeding, if it is occurred, is often attributed to hemorrhoids, a common finding of pregnancy and many of these symptoms are commonplace in normal pregnancy. This delays diagnosis of colorectal cancer during pregnancy and leads to more advanced stage and poor prognosis compared to the general population. We experienced a woman at 27 weeks gestation who complained of low abdominal distention and was diagnosed of sigmoid colon cancer and underwent cesarean section and hemicolectomy at 30 weeks gestation, so we present it with brief review of literature."
Anemia
;
Anorexia
;
Cesarean Section
;
Colorectal Neoplasms*
;
Constipation
;
Diagnosis
;
Female
;
Hemorrhage
;
Hemorrhoids
;
Humans
;
Incidence
;
Nausea
;
Pregnancy*
;
Prognosis
;
Sigmoid Neoplasms
;
Vomiting
;
Weight Loss
7.Influence of Knowledge about Lung Cancer, Attitude and Preventive Health Behavior about Cancer on Nicotine Dependency in Smoking Male College Students.
Journal of Korean Biological Nursing Science 2016;18(4):213-220
PURPOSE: The aim of this study was to identify the influence of knowledge, attitude and preventive health behavior of cancer on nicotine dependency in male college students who have a habit of smoking. METHODS: In this study, a cross-sectional survey design was adopted for the 254 male college students who smoke in D and S city. The data was analyzed for descriptive statistics, t-test, Pearson's correlation coefficient and multiple regression analysis using the SPSS 20.0 program. RESULTS: Knowledge about lung cancer (β=-.407, p<.001), preventive health behaviors about cancer (β=-.223, p<.001) and the smoking period (5years≤) (β=.198, p=.001) were identified as the factors influencing nicotine dependency of the subjects. The model explained 33% of variance in nicotine dependency (F=20.49, p<.001). CONCLUSION: The results suggest that anti-smoking educators should include the strategies to increase knowledge about lung cancer and preventive health behaviors of cancer, and to reduce the smoking period in their smoking cessation program.
Cross-Sectional Studies
;
Health Behavior*
;
Humans
;
Lung Neoplasms*
;
Lung*
;
Male*
;
Nicotine*
;
Smoke*
;
Smoking Cessation
;
Smoking*
8.Delayed Cardioprotective Effect of Ischemic Preconditioning is mediated by Heat Shock Protein in Cat Heart.
Jong Seon PARK ; Gue Ru HONG ; Dong Gu SHIN ; Young Jo KIM ; Bong Sup SHIM
Korean Circulation Journal 2001;31(1):16-23
BACKGROUND: It is well known that ischemic preconditioning protects the heart against infarction or arrhythmias from a subsequent ischemic injury. Two phases of the effect of preconditioning has been explored, early protection and second window of protection at 24 hours. The late protection was seen in some animal model, but the precise mechanism is controversal. This study was designed to evaluate the late cardioprotective effect and role of HSP70 in ischemic preconditioning of cat heart. METHODS: Two groups of cats were studied. Control animals were subjected to an episode of 40-min coronary artery occlusion followed by 30-min reperfusion. Experimental animals were subjected to ischemic preconditioning before the 40-min ishcemia/reperfusion. The preconditioning protocol was comprised of three 5-min episodes of ischemia interspersed by 10-min episodes of reperfusion. After sustained ischemia and reperfusion, left ventricular risk area and infart area were measured by injection of Evans blue bye and triphenyltetrazolium staining, and myocardial HSP70 mRNA was examined in risk(left ventricular anterior wall) and nonrisk(left ventricular posterior wall) area using northern blot hybridization. HSP70 mRNA expression was quantified as a percent of GAPDH. The late cardioprotective effects of ischemic preconditioning were determined by infarct size (% area at risk). RESULTS: Infarct size was markedly limited by ischemic preconditioning when compared with the control group (18.5+/-6.9% vs 38.5+/-11.1%; p<0.001). HSP70 mRNA expression in risk area was much higher in preconditioning group than control group(78+/-12% vs 41+/-11%; p<0.01). But, there was no significant difference of HSP70 mRNA expression in the posterior wall between control and ischemic preconditioning group. CONCLUSIONS: These data suggest that ischemic preconditioning have delayed myocardial protective effect from ischemia. The increase in myocardial HSP70 mRNA may be one of the contributing factors to the delayed cardioprotective effects of ischemic preconditioning in cats.
Animals
;
Arrhythmias, Cardiac
;
Blotting, Northern
;
Cats*
;
Coronary Vessels
;
Evans Blue
;
Heart*
;
Heat-Shock Proteins*
;
Hot Temperature*
;
HSP70 Heat-Shock Proteins
;
Infarction
;
Ischemia
;
Ischemic Preconditioning*
;
Models, Animal
;
Reperfusion
;
RNA, Messenger
9.Effects of morphine and naloxone on ex-vivo human colon by intraarterial perfusion.
Hong Ki KIM ; Hyo Sub YOON ; Chang Soon JO ; Byoung Yoon RYU ; Chang Sig CHOI
Journal of the Korean Surgical Society 1991;41(4):525-534
No abstract available.
Colon*
;
Humans*
;
Morphine*
;
Naloxone*
;
Perfusion*
10.The evaluation of the endometrial curettage in patients of ectopic pregnancy.
Young Mi SUNG ; Yoon Ho JO ; Byoung Sun KIM ; Keun Young PARK ; Seo Yoo HONG
Korean Journal of Obstetrics and Gynecology 1993;36(7):1261-1267
No abstract available.
Curettage*
;
Female
;
Humans
;
Pregnancy
;
Pregnancy, Ectopic*