2.Hyperkeratosis of the Nipples Developed during Pregnancy: report of a case.
Se Hong PARK ; Jae Joon KIM ; Jae Hong KIM
Korean Journal of Dermatology 1981;19(6):933-937
Hyperkeratosis of the nipple and areola is rare dermatosis that may be divided into three categories: a type of epidermal nevus, a type associated with ichthyosis and a type of nevoid form seen in voung women. A 23-year-old woman was seen for skin lesion involving both nipples. These changes were first noted when the patient was in the sixth month of gestation. Physical examinations revealed papillomatous thickening of both nipples with brownish black discoloration. Histopathological changes were mild hyperkeratosis, keratotic plugging and telangiectasia. It was interesting to note that the skin lesions disappeared spontaneously 7 days after parturition without treatment. A possible correlation between pregnancy and acquired form of this rare skin disorder is suggested.
Female
;
Humans
;
Ichthyosis
;
Nevus
;
Nipples*
;
Parturition
;
Physical Examination
;
Pregnancy*
;
Skin
;
Skin Diseases
;
Telangiectasis
;
Young Adult
3.A Case of Herpes Zoster with Generalized Varicella like Eruption.
Jae Joon KIM ; Se Hong PARK ; Jae Hong KIM
Korean Journal of Dermatology 1981;19(6):957-961
Generalized varicella-like eruption occurs in 2 to 10 percent of unselected patients with localized zoster, the majority of whom are patients with immunologic defects due to underlying malignanies (particularly rnalignancy of hematopoietic system) or immunosuppressive therapy. A 25-year old male noted onset of pain and burning sensation on the right side of cheet nine days prior to admission. The following day multiple vesicles were noted on right side of the chest. Three day before the admisson erythernatous maculopapules were noted on the abdomen. One day prior to admission vesicular lesions appeared over the entire hody. The patient was treated with topical application of calamin lotion, and with kanamycin and Cephalexin to prevent secondary infection. The secondary vesicles had disappeared by the fifth hospital day, but the initial lesion had not improved. On the fifteenth hosptital day the initia1 lesions has disappeared.
Abdomen
;
Adult
;
Burns
;
Cephalexin
;
Chickenpox*
;
Coinfection
;
Herpes Zoster*
;
Humans
;
Kanamycin
;
Male
;
Sensation
;
Thorax
4.Clinical Manifestations of Salmonellosis in Children during the last 12 Years: A Single Institution Experience.
Korean Journal of Pediatric Infectious Diseases 2013;20(1):1-8
PURPOSE: The purpose of this study is to investigate the clinical manifestations and antibiotic resistance of salmonellosis in children. METHODS: We reviewed medical records and investigated the clinical characteristics of culture-proven childhood salmonellosis from January 2000 through December 2011 at the CHA Bundang Medical center. RESULTS: We assessed 53 patients. The median age was 3-years-old (minimum 12 days, maximum 18-years-old) and the number of male patients was 33 (62.3%). It occurred most frequently in the summer (39%) and in 2001 (11 cases) however there was no case in 2009 and 2010. Salmonella typhi was isolated in 3 cases with septicemia. Antibiotic resistance to ampicillin was most frequently presented (30.2%) and 63.6% in serogroup B. No antibiotics resistance strains were cultured in patients with positive Salmonella typhi. Admitted patients from 2000 to 2011 were divided into 2 groups; group 1 from 2000 to 2005 and group 2 from 2006 to 2011. 40 cases belonged to group 1 and 13 cases were in the group 2. Group 2 showed more resistance to ampicillin than group 1 but without any statistical significance(25% vs. 38.5%, P=0.349). In group 1, the most common serotype was group D and in group 2, the most common serotype were group C and D. CONCLUSION: Salmonellosis in children was frequently occurred from 2000 to 2003 but decreased after 2004. There was no difference in clinical manifestations, serotypes and antibiotic resistances between the years.
Ampicillin
;
Anti-Bacterial Agents
;
Child
;
Drug Resistance, Microbial
;
Humans
;
Male
;
Medical Records
;
Salmonella Infections
;
Salmonella typhi
;
Sepsis
5.Increasing Rates of Community Associated Methicillin-Resistant Staphylococcus aureus in Children with Muscular-Skeletal Infections in Korea: A Single Center Experience from 2000 to 2012.
Korean Journal of Pediatric Infectious Diseases 2013;20(2):63-70
PURPOSE: This study aimed to explore how prevalent the community-related methicillin-resistant Staphylococcus aureus (CA-MRSA) was in children with muscular-skeletal infections. METHODS: We retrospectively reviewed the medical records of patients of 18 years or under who were diagnosed with suppurative arthritis or osteomyelitis and S. aureus from September 2000 through August 2012 at the CHA Bundang Medical center. RESULTS: Thirty-one cases of suppurative arthritis or osteomyelitis were identified. The patients were between 17 days old and 18 years old with an average age of 7. Eleven cases (33.5%) of suppurative arthritis and 16 cases (51.6%) of osteomyelitis were observed. Five cases were accompanied by the two diseases. Methicillin sensitive S. aureus (MSSA) was isolated in 25 cases (80.6%) and methicillin resistant S. aureus (MRSA) was isolated in 6 cases (19.4%). Multidrug resistant strains were not observed. MRSA was not found from 2000 through 2005. All patients were treated with antibiotics and the duration of antibiotics treatment was 26.4+/-12.7 days. Vancomycin was used as the initial antibiotic treatment in 4 cases (12.9%) and vancomycin was used as the definitive antibiotics in the 10 cases (32.3%). CONCLUSIONS: The result of this study showed that methicillin resistance rate of S. aureus from muscular-skeletal infections was concentrated in the latter half of the 12 year period.
Anti-Bacterial Agents
;
Arthritis, Infectious
;
Child
;
Humans
;
Medical Records
;
Methicillin
;
Methicillin Resistance
;
Methicillin-Resistant Staphylococcus aureus
;
Osteomyelitis
;
Retrospective Studies
;
Vancomycin
6.Analysis of foreign body in the children's airway and follow-up study.
Journal of the Korean Pediatric Society 1993;36(2):169-178
The author analysed foreign body in the airway, divided into two groups vegetable foreign body group(VFBG) and non-vegetable foreign body group(N-VFBG), according to the nature, in 88 patients aged from 5 months to 15 years who were diagnosed and treated under ventilating bronchos-copy at Department of Pediatrics and Otolaryngology, Pusan National University Hospital from 1980 to 1990. Of the 88 patients analysed, 13 were followed for review, which comprised clinical assessment, chest radiography, and perfusion lung scan. The follwing results were obtained. 1) The highest incidence was seen in the age group of 1 to 3 years old especially in VFBG, bur no difference in incidence among each age group was observed in N-VFBG, The ratio of incidence between male to female was 2:1 ein total and, in N-VFBG, the incidence of male 8 times higher than female. 2) A wide variety of foreign bodies was recovered, with peanut being by far the most common (50%) and the ratio of incidence between VFBG and N-VFBG was 6 to 4. 3) The time interval of less than 24 hours between aspiration and admission was most frequently seen in 38% and of more than 3 weeks in 11%. The time interval in VFBG and the group with left bronchial lodging was longer than of N-VFBG and the group with right bronchial lodging, each respectively but no statistical difference was observed. The time interval in the group with bronchial lodging was significantly longer than of the group with laryngeal and tracheal lodging. 4) Frequent symptoms and signs were coughing, dyspnea, fever, decreased air entry, coarse breathing sound and rales. In total, clinical manifestations were more common in VFBG, especially in the incidence of fever, decreased air entry, coarse breathing sound and rhonchi. 5) The roentgenographic findings on admission were emphysema, pneumonia and atelectasis in the order of frequency. The incidence of emphysema and complex roentgenographic findings were more common in VFBG whereas in N-VFBG radioopaque foreign body normal roentgenographic findings were more common. 6) The prevalence of bronchial lodging was over 70% regardless of age group. No difference of predilection was observed between right and left bronchial lodging before 7 years old, but after 7 years old right bronchial lodging was significantly seen. 7) The longer the time lag before admission after aspiration, the longer the duration of hospitalization was in VFBG but with no statistical significance. However, no correlation between time lag and the duration o hospitalization was observed in N-VFBG. The group with bronchial lodging had significantly longer duration of hospitalization compare to that of the group with laryngeal and tracheal lodging, The group with left bronchial lodging had longer duration of hospitalization compare to that of the group with right bronchial lodging but with no statical significance. 8) Of the 13 cases reviewed, one had abnormal lung perfusion scan in spite of normal clinical assessment and chest X-ray, who was treated on 20 days days after aspiration of peanut in the right bronchus.
Bronchi
;
Busan
;
Child
;
Child, Preschool
;
Cough
;
Dyspnea
;
Emphysema
;
Female
;
Fever
;
Follow-Up Studies*
;
Foreign Bodies*
;
Hospitalization
;
Humans
;
Incidence
;
Lung
;
Male
;
Otolaryngology
;
Pediatrics
;
Perfusion
;
Pneumonia
;
Prevalence
;
Pulmonary Atelectasis
;
Radiography
;
Respiratory Sounds
;
Thorax
;
Vegetables
7.A Clinical Observation on 55 Cases of Neonatal Sepsis.
Yeungnam University Journal of Medicine 1988;5(2):161-169
Neonatal Sepsis is a frequent and important cause of morbidity and mortality in the neonatal period. This study was undertaken to observe the 55 cases of proven neonatal sepsis among 6,717 newborn infants under 4 weeks of age, admitted to the nursery of Yeungnam University Hospital from May 1, 1983 to April 30, 1988. We observed following results: 1. The morbidity rate of male (1.12%) was higher than that of female (0.44%) significantly (p<0.05). 2. The morbidity rate of prematurity (2.65%) was higher than that of full term (0.76%) significantly (p<0.05). 3. The incidence of perinatal obstetric complications in early onset neonatal sepsis was higher than that of late onset neonatal sepsis (38.5% vs 10.3%, p<0.05). 4. The common clinical manifestations were poor feeding (52.7%), jaundice (45.5%), diarrhea (30.9%) and irritability (30.9%). 5. Among the causative organism, gram positive organisms were predominated and Staphylococcus epidermidis was the most common organism. There was no difference in the causative organisms between early onset and late onset sepsis.
Diarrhea
;
Female
;
Humans
;
Incidence
;
Infant, Newborn
;
Jaundice
;
Male
;
Mortality
;
Nurseries
;
Sepsis*
;
Staphylococcus epidermidis
8.Bacteriological Study of Pyodermas.
Korean Journal of Dermatology 1981;19(3):285-292
Bacteriological study, including antibiotic sensitivity tests, of 81 patients with pyodermas such as impetigo, folliculitis, furuncle, carbuncle, cellulitis and acuete infectious eczematoid dermatitis, was carried out during 4 months period from June, 1980 to September, 1980 at the department of dermatology, Han Il Hospital. The results were as follows: 1) The causative agents of impetigo in 42 patients, were coagulase positive Staphylacoccus aureus in 33, p-hemolytic Streptococcus in 6 and both organisms in R (S. aureus and 3-hemolytic Streptococcus). Coagulase negative Stgaphylococcus was not found. 2) The causative agents of superficial and deep follicultis in 23 cases, were coagulase positive S. aureus in 12, coaulase negative Staphylococcus in 5, p-hemolytic Streptococcus in 4 and S. aureus and p-hemolytic Streptococcus in 3. 3) The causative agents of cellulitis in 2 cases, were coagulase positive S. aureus in 1, and coagulase negative Staphylococcus in 1. 4) The causative agents of acute infectious eczematoid dermatitis in l4 cases, were coagulase positive S. aureus in 6, coagulase negative Staphylococcua in 1, p-hemolytic Streptococcus in 2, and two organisms in 5 (4 cases were mixed).
Carbuncle
;
Cellulitis
;
Coagulase
;
Dermatitis
;
Dermatology
;
Folliculitis
;
Furunculosis
;
Humans
;
Impetigo
;
Pyoderma*
;
Staphylococcus
;
Streptococcus
9.A Case of Hypereosinophilic Syndrome.
Se Hoon PARK ; Jae Joon KIM ; Jae Hong KIM
Korean Journal of Dermatology 1982;20(4):569-575
The hypereosinophilic syndrome consists of peripheral blood eosinophilia of 1500/ mm3 or more without a known cause, plus signs and symptoms of organ eosinophilia. We report a case of hypereosnophilic syndrome with cutaneous manifestation. A 31 year-old female had intermittent fever, sbdominal pain, anemia, systolic murmur, hepatosplenomegaly, cheat discomfort, dry cough without rales, and skin-colored wheal on the trunk. Diagnoais of hypereosinophilic syndrome wss established by clinical findings, marked blood eosinophilia without a known cause, bone marrow aspiration and biopsy, liver scan, and histopsthologic findings of the skin.
Adult
;
Anemia
;
Biopsy
;
Bone Marrow
;
Cough
;
Eosinophilia
;
Female
;
Fever
;
Humans
;
Hypereosinophilic Syndrome*
;
Liver
;
Respiratory Sounds
;
Skin
;
Systolic Murmurs
10.Regression of Herniated Nucleus Pulposus after Anterior Interbody Fusion
Jae In AHN ; Heui Jeon PARK ; Jae Hong LEE
The Journal of the Korean Orthopaedic Association 1988;23(1):165-172
Low back pain and sciatica is one of the most frequent and troublesome problem in or thropedic field. There are many controversies about surgicsl procedure for the treatment of the patient with herniated nucleus pulposus. The advantages of anterior interbody fusion are through removal of remnsnt of the disc, restoration of disc height, correction of spinal alignment, preservation of posterior elements and neural component. The strut of ilisc bone was firmly impacted and patients could be mobilization earlier. It is well known that symptoms secondary to herniated nucleus pulposus can resolve after disc excision and anterior interbody fusion, but little has been written about regression of herniated nucleus pulposus. We analysed 20 cases in which serial C-T studies disclosed an unequivocal regression or complete disappearance of nucleus pulposus after anterior interbody fusion. The results were summerized as followings ; 1. Regression of herniated nucleus pulposus was average 2.65mm. 2. The clinical results were excellent in 20% of the patients, good in 60% and fair in 20% 3. The comparision are based on the finding at C-T, marked regression(>4mm), was in 19%, moderate regression(2~4mm) in 59% snd minimal regression(<2mm) in 22%. 4. The clinical results were correlated to amount of regression of herniated nucleus pulposus.
Humans
;
Low Back Pain
;
Sciatica