Asthma ; diagnosis ; therapy ; Child ; Chronic Disease ; Cough ; diagnosis ; therapy ; Humans

Asthma ; diagnosis ; therapy ; Child ; Humans

Child ; Child, Preschool ; Humans ; Hypersensitivity, Immediate ; prevention & control ; Infant ; Primary Prevention

Recent studies have suggested that C-peptide in the nanomolar concentration range binds specifically to cell surfaces and plays an important role in the pathological mechanism of chronic complications of diabetes mellitus, via improving the microcirculation, diminishing glomerular hyperfiltration, reducing urinary albumin excretion, protecting the cardiac function and preventing nerve dysfunction. The effects of C-peptide on the development of the chromic diabetic complications and its mechanisms are reviewed.

Volatile organic compounds (VOCs) are organic chemicals which can exist in the form of vapor at room temperature.Endogenous VOCs can be produced by different biochemical processes in the human body.They can be transfered to lung through bloodstream and released through breath.Many researches show that exhaled VOCs can be significantly changed when people suffering cancers or inflammation. Detecting exhaled VOCs through instrument with high sensitivity make it possible to detect cancers in early phase in a noninvasive and rapid way,which reduce the suffering of patients.In conclusion,exhaled VOCs detection is a promising method for early diagnosis of cancers.

Adult ; Aged ; Aged, 80 and over ; Cadmium ; blood ; Case-Control Studies ; Coronary Disease ; blood ; Female ; Humans ; Lead ; blood ; Male ; Middle Aged

Anti-Asthmatic Agents ; therapeutic use ; Asthma ; diagnosis ; drug therapy ; Emphysema ; Female ; Humans ; Male

AIM: To observe the efficiency of phacoemulsification with intraocular lens implantation in the treatment of cataract and glaucoma.
METHODS:Totally 60 patients ( 70 eyes ) with cataract and glaucoma were included between March 2010 and March 2012 in our hospital. The phacoemulsification with intraocular lens implantation was performed. The observation of surgical efficiency, including the patient's IOP, anterior chamber depth, vision and complications, were compared before and after surgery.
RESULTS:Compared with preoperation, the patients'vision and anterior chamber depth were increased and the IOP was reduced significantly (P<0. 05).
CONCLUSION: Phacoemulsification with IOL implantation is a safe and effective treatment for cataract and glaucoma.

Objective To investigate the neuroprotection of different brain regions after transplantation of genetically modified myoblasts producing brain derived neurotrophic factor (BDNF) into cortices of neonatal rats subjected to hypoxic ischemic encephalopathy (HIE). Methods Seven day old pups were randomized into sham operated group (C), HIE+BDNF group (B) and HIE+mock transplantation group (A). A rat myoblast cell line expressing and secreting BDNF (BDNF(+)/L 6TG) was constructed. A stereotaxical intracerebroparenchymal transplantation of either BDNF(+)/L 6TG (B) or BDNF(-)/L 6TG (absence of BDNF, A) at 0.8 ?l of cell suspension (4?10 4/?l) into the left cortex of the brain was carried out shortly after HIE undergone by ligation of left common carotid artery followed by a 2.5 h inhalation of humidified 8% O 2+92% N 2 at 37℃. Changes of areas of different brain regions of cortex, hippocampus and striatum at different sections were observed 21 d after the procedure. Injury severity scores of brain tissues were also performed. Results Twenty one days after the manipulation, various degrees of atrophy were observed in the three regions of left hemispheres in group A or B versus contralateral corresponding regions or group C whereas this atrophy in group B was significantly reduced when compared to group A. Not only was the atrophy of cortex near the grafting point alleviated but some other regions of left hemispheres. A similar change pattern was seen in injury severity scores of the tissue. Conclusion Present data suggest that intracerebral transplantation of genetically modified myoblasts producing BDNF has a beneficial effect on the protection from damage of both circumscriptus brain tissues and some other areas distanced from the grafted place.