Lichen planus with herpes zoster which showed generalized hyperpigmentation, plated papular eruption, fine scale and vesicular eruption on the right thigh were reported and the literatures of lichen planus were reviewed. The case was 41 years old man, who began to have itching, erythem and fine scale 6 years ago, but had no other symptom. Histopathologically, epidermis was hyperkeratotic, acanthotic and granular layer thickening and vesicular formation.
Adult ; Epidermis ; Herpes Zoster* ; Humans ; Hyperpigmentation ; Lichen Planus ; Pruritus ; Thigh

Author reported a case of Ritters disease,, 12 days old, male, who had visited with complaining generalized skin exfoliation. This patient was suffered from erythematous papules, vesicles and bullae on entire body from 7 days ago. He was treated with antibiotics and antibiotic ointment, and was discharged.
Anti-Bacterial Agents ; Humans ; Male ; Skin ; Staphylococcal Scalded Skin Syndrome*

A case report of a 6p-year-old man with crokeratosis verruciformis on the dorsa of hands & forearms is presented. This case is unusual in that the patient had late onset of the lesions and lack of a family history of the condition. Literatures are reviewed and possible linkage with Darier's disease is discussed.
Darier Disease* ; Forearm ; Hand ; Humans

The study was made in order to investigate the present status of superficial dermatomycoses and some changes on the frequency of the diseases, sex distribution and varieties of the causative organisms by the statistic and mycological observation. The survey was made by out-patients of Dermatology clinic of Seoul National University during 3 years, from 1967 to 1970. The results are as follows: 1. Tinea (T) capitis shows a great decrease (1/4) and T. cruris shows a increase in number as compared with those of during 1957-1960. 2. In T. capitis the number of male cases is equal to that of female cases. It is remarkable difference that the ratio of sex distinetion showed 25 males against to one female during 1967 to 1970. 3. The strains were isolated by ordinary sabouraud's glucose agar media and obtained 4 species, 125 strains. a. Tr. rubrum was most predominant organism of T. pedis & manum, T. cruris, T. corporis and Onychomycosis in Seoul districs. b. Tr. ferrugineum was most common organism of T. capitis (80%).
Agar ; Dermatology ; Dermatomycoses* ; Female ; Glucose ; Humans ; Male ; Onychomycosis ; Outpatients ; Seoul ; Sex Distribution ; Tinea

No abstract available.
Hepatitis* ; Interferons* ; Lamivudine*

No abstract available.
Gallstones*

No abstract available.
Arthrodermataceae* ; Korea*

1. The saturated solution of starch, inulin and lactose could not inhibit the growth in media of monilia albicans. Trichophyton interdigitable and alternaria species. 2. In the cultivation findings of monilia albicans shows imperfect or dysfigured elementary pattern in saturated maltose, mannitol and ruffinose media, and was inhibited the growth by sucrose and dextrose lotion. 3. Saturated mannitol solution inhibit growth of trichophyton interdigitable strain and mannitol and dextrose inhibit the alternaria cultivation.
Alternaria ; Candida ; Fungi* ; Glucose ; Inulin ; Lactose ; Maltose ; Mannitol ; Saccharum* ; Starch ; Sucrose ; Trichophyton

INTRODUCTION: In 1910 phenylephrine hydrochloride was introduced first by Barger and Dale. Phenylephrine hydrochloride is a synthetic sympathomimetic compound structurally similar to epinephrine and ephedrine. Synthetic phenylephrine hydrochloride is clinically used as a nasal decongestant, vasopressor and mydriatic, etc.. The use of phenylephrine hydrochloride in ophthalmological practice is based on its action of vasoconstriction and mydriasis. Phenylephrine hyrdochloride has been introduced in U.S.A. as 10 % neosynephrine (U.S.P.) and in Japan as 5 % neosynesine. It's usefulness in therapy and examination is due to the following characteristics; (1) Rapid effect, (2) No influence on intraocular pressure nor on accommodation, (3) No undesirable side reaction. In many countries including U.S.A. and Japan. they reported experimentally and clinically in detail about the mydriatic action of phenylephrine hydrochloride but unfortunately there is no data concerning mydriatic action of phenylephrine hydrochloride in Koreans in spite of its wide use in ophthalmology. The study was performed for dilatation of the pupil, influence on intraocular pressure and accommodation, antagonistic action to pilocarpine, and side reaction after instillation of 10 % neosynephrine (U.S.P.) by the following method. METHOD AND MATERIAL: Material; 10 % Neosynephrine hydrochloride (U.S.P.), 2 % Pilocarpine. Subjects; 228 Korean normal eyes (6-84 yrs. old). METHOD: 1. Dilatation of the pupil (176 eyes). Group 1; One drop of 10 % neosynephrine instilled into 75 eyes. Over 60 yrs. old--10 eyes, 36-59 yrs. old--17 eyes, Under 35 yrs. old--48 eyes. Group 2; Two drops of 10 % neosynephrine instilled into 59 eyes. Over 60 yrs. old--2, eyes 39-59 yrs. old--17 eyes, Under 35 yrs, old--40 eyes. Group 3; Three drops of 10 % neosynephrine instilled into 42 eyes. Over 60 yrs. old--7 eyes, 36-59 yrs. old-14 eyes, Under 35 yrs. old-21 eyes. Interval between each instillation was two or three minutes. After instillation of 10 % neosynephrine into the eyes, the diameter of the pupils was measured frequently till maximum dilatation. 2. Influence on the intraocular pressure (25 eyes). After measurement of the intraocular pressure and diameter of the pupil in eacheyes, one drop of 10 % neosynephrine was instilled into 9 eyes and two drops into 10 eyes, and three drops into 6 eyes. After that measurement of intraocular pressure and diameter of the pupil was done every 10 minutes for 90 minutes and 2 and 3 hrs. later. 3. Influence on accommodation. The diameter of the pupil and distance of N.P.C. were measured before instillation of neosynephrine and every 10 minutes interval for 90 minutes and at 2 and 3 hrs. after instillation of 10 % neosynephrine into 23 eyes (one drop into 8 eyes, two drops into 10 eyes, three drops into 5 eyes). 4. Antagonistic action of 2 % pilocarpine to mydriatic action of 10 % neosynephrine. In two eyes of a 26 yrs. old man, diameter of the pupil was measured and compared in both eyes before instillation of one drop of 10 % neosynephrine and in 10 minutes interval to 90 minutes, at 2 and 3 hrs. after instillation of one drop of 10 % neosynephrine intoboth eyes. Then one drop of 2 % pilocarpine was instiIled into only the right eye at 50 minutes after first instillation of neosynephrine. One drop of 10 % neosynephrine was instilled into both eyes of a 23 yrs. old man, two drops into both eyes of a 20 yrs. old man. and three drops into both eyes of a man aged 22 yrs. One drop of 2 % pilocarpine was instilled into only the right eye of each person, respectively at 40 minutes (22 yrs. old eye), 50 minutes (20 yrs. old eye), and 60 minutes. (23 yrs. old eye) after first instillation of neosynephrine. The diameter of the pupil, the distance of N.P.c., and the intraocular pressure were measured and compared in both eyes of each person befere instillation and at 10 minutes intervals for 90 minutes. and at two and three hrs. after first instillation. RESULTS AND CONCLUSION: 1. In most of 176 eyes, the diameter of the pupils reached more than 7.5mm (maximum dilatation) and they took an average of 42 minutes to reach their maximum dilatation Among them, the shortest was 26 minutes and the longest 75 minutes. 2. The time the pupil takes to reach its maximum dilatation is a little differance between group 1 (one drop of neosynephrne instilled) and group 2 (two drops of neosynephrine instilled) but definetely shorter in group 3 (three drops of neosynepphrine instilled). 3. 10 % neosynephrine has little influence on intraocular pressure. 4. 10 % neosynephrine has slight influence on accommodation (slight paresis of accommodation) in about half of 26 eyes hut they have no disturbance at near work (Table 2 and 3). 5. 2 % pilocarpine constricts the dilated pupil more quickly than if not used (Table 4.). 6. Age has no effect on dilatation of the pupil due to instillation of 10 % neosynephrine. 7. No undesirable side reaction was noted.
Dilatation ; Ephedrine ; Epinephrine ; Humans ; Intraocular Pressure ; Japan ; Mydriasis ; Ophthalmology ; Paresis ; Phenylephrine* ; Pilocarpine ; Pupil ; Vasoconstriction

Author observed histopathologically and immunologically the old lepers of 360 cases, having the duration of infection with average 11 years and 5months. Here summarize as follows : 1. Microscopically in L-type, lepra cells, or Virchow cells (foamy cells) were relatively large, and the infiltration showed the tendency to concentrate particularly around the periglandular regions. Free zones were mostly obscure and disappeared. 2. Tuberculoid structure tends to be obscured in T-type of leprosy. 3. The healings showed few granulomatous infiltration, rather the almost normal findings. But periglandular and perivascular infiltrates were present. 4. Lepromin test was considerably positive in T-type of leprosy (about 57.8%)
Lepromin ; Leprosy