For confirmative diagnosis of bone and joint tuberculosis, it is made by culture method, inoculation to guinea pig, or histological examination of the specimen obtained from a lesion site. But plain reontgenogram is not valuable for early detection of the disease because specific, abnormal finding is not found in early stage and only found in late stage as progressive destruction of bone and joint. Many reports were made thst whole body bone scan, as diagnostic tool, was valuable in other orthopedic disease, but report for its diagnostic value in bone and joint tuberculosis is very rare. The study was carried out on 35 patients of bone and joint tuberculosis who whole body bone scan was performed before operation from Janusry, 1978 to December, 1987 in Depaartment of Orthopedic Surgery, Yonsei University college of Medicine. The following results were obtained. 1. Value of early detection of tuberculosis is not much as pyogenic infection. Intensity of uptake was decreased in tuberculosis than acute pyogenic osteomyelitis and arthritis, but increased than chronic osteomyelitis. 2. Intensity of uptake was decreased in female than male, and also increased in age. group under 10 and over 60 than other age group. 3. The longer duration of the disease, the more decreased intensity of uptake. 4. Intensity of uptake is increased in joint tuberculosis than bone, snd also increased in tuberculosis of spine than long bone. 5. Multifocal disease was detected in 14.3% by whole body bone scan.
Animals ; Arthritis ; Diagnosis ; Female ; Guinea Pigs ; Humans ; Joints ; Male ; Methods ; Orthopedics ; Osteomyelitis ; Spine ; Tuberculosis ; Tuberculosis, Osteoarticular

Cubitus varus and valgus is one of late complication of elbow fracture, and this deformity is caused usually by malunion in supracondylar fracture or epiphysial injury of the elbow joint. 40 supracondylar closed wedge osteotomies (on cubitus varus 25, cubitus valgus 15) were performed at the supracondylar level and were fixed with two K-wires or French method. The following results were obtained: 1. The frequency of deformity of cubitus varus was higher than that of cubitus valgus: cubitus varus, 25 cases and cubitus valgus, 15 cases. 2. Injury of the supracondylar of the humerus frequentry occured between the age of 6 and 15 (65%). 3. In cubitus varus the degree of deformity ranging from −11° to −30° was the most common whereas in cubitus valgus that ranging from 30° to 40°, 4. Incomplete ulnar nerve palsy was revealed in 15 postoperative cases of cubitus varus of which 3 cases were treated by anterior transposition. In all cubitus valgus, tardy ulnar nerve symptom was disappeared after correction. 5. Nerve damage could be avoid by performing the closed wedge osteotomy and upper connection combind with posterolateral incision in cubitus varus and medial incision in cubitus valgue. 6. Internal fixation associated with cross pinning with two K-wires or French method were performed and good result was obtained without complication even though older case.
Congenital Abnormalities ; Elbow ; Elbow Joint ; Humerus ; Methods ; Osteotomy ; Ulnar Nerve ; Ulnar Neuropathies

No abstract available.
Female ; Methotrexate* ; Pregnancy ; Pregnancy, Tubal*

No abstract available.
Esophageal and Gastric Varices* ; Hypertension, Portal*

No abstract available.
Chungcheongbuk-do* ; Leptospira interrogans* ; Leptospira*

No abstract available.
Pancreaticoduodenectomy* ; Risk Factors*

Vimentin is an intermediate filament protein normally expressed in mesenchymal cells, but the evidence of the aberrant expression of vimentin in epithelial cancer cells suggests that the vimentin expression might be related to local invasiveness and metastatic potential. There have been a few previous studies on the vimentin expression in human cervical carcinogenesis using in vivo and in vitro models. We examined the immunohistochemical vimentin expression in various squamous epithelial neoplasms of the uterine cervix, including the cervical intraepithelial neoplasia group (n=25), the microinvasive squamous cell carcinoma group (n=15), the invasive squamous cell carcinoma group (n=15) and the metastatic squamous cell carcinoma group (n=8). Vimentin positivity was significantly higher in the invasive than in the intraepithelial group, and in the cases with lymph node metastasis than in those without metastasis, suggesting a relationship between the vimentin expression and progression of the uterine cervical epithelial tumors.
Carcinogenesis ; Carcinoma, Squamous Cell ; Cervical Intraepithelial Neoplasia ; Cervix Uteri* ; Female ; Humans ; Intermediate Filaments ; Lymph Nodes ; Neoplasm Metastasis ; Neoplasms, Glandular and Epithelial* ; Vimentin*

No abstract available.

Achilles tendon is the most powerful tendon of the body and increases efficiency in weight bearing and walking capability. Since pares' report about the rupture of the Achilles tendon many authors have reported various causes, diagnostic and therapeutic methods. Most of the authors emphasized the early diagnosis and treatment resulted in good prognosis. There are many methods for the diagnosis of the Achilles tendon, roentgeography, angiography, electromyography, histologic examination and Thompsons test. The causes of the rupture of the Achilles tendon are direct and indirect injury. The two methods of treatment are conservative management and surgical treatment. Whether the cause of the injury is direct or indirect, restoration of function after treatment must be emphasized and the proper method of treatment must be determined by the degree of injury. Clinical analysis was done on 15 cases of Achilles tendon rupture treated at Orthopedic Department of Capital Armed Forces General Hospital from Oct. 1973 to Oct. 1978 with the following results. 1. In sex distribution, there were 13 male cases and 2 female cases and the age range of 20 to 30 years old was the most frequent (67%). 2. There was no difference In frequency between the right and the left side. 3. Achilles tendon rupture was two times more frequent in indirect cause than direct cause, especially after falling from heights and exercises. 4. The most frequent site of rupture was 2–5 Cm. above the insertion of the tendon (80%). 5. By means of a cost immobilization, good result was obtained in fresh partial rupture of the tendon. 6. Good results were obtained by end-to-end suture in fresh cases and reconstructive surgery in old cases. 7. Most of the patients returned to their jobs about 6 months after the operation.
Accidental Falls ; Achilles Tendon ; Angiography ; Arm ; Clinical Study ; Diagnosis ; Early Diagnosis ; Electromyography ; Exercise ; Female ; Hospitals, General ; Humans ; Immobilization ; Male ; Methods ; Orthopedics ; Prognosis ; Rupture ; Sex Distribution ; Sutures ; Tendons ; Walking ; Weight-Bearing

The thoracolumbar fracture and fracture-dislocations are ever increasing today as the traffic accidents and industrial accidents frequently occur. But the controversy as to the relative values of early surgical instrumentation and conservative means has continued for well over a decade. The duration of this dispute without final resolution suggests an absence of significant differences in the results of surgical and non-surgical method. The purpose of this study is to review the results of conservative treament for 132 patients with thoracolumbar fracture and fracture-dislocations, who were admitted and treated at Yonsei University Severance Hospital from January, 1980 to December, 1984. And we obtained following results. l. In cases of stable fracture without neurologic deficit, especially when the wedging deformity of vertebral body is below 50%, it seems to be better to treat conservatively; that is, immediate postural reduction and after 2 or 3 weeks of bed rest, to start ambulation with back brace or cast. 2. In cases of stable fracture with neurologic deficit, operative treament is necessary when the frac-fragment is protruded into the spinal canal and neural compression sign is evident. But if not so, attempt to treat by conservative means may be done. 3. In cases of unstable fracture without neurologic deficit, it is more retional to treat conservatively by bed rest for a suffient time and then wearing back brace or cast. If the spinal deformity is so severe that it needs spinal fusion, the operation can be performed later on. 4. In cases of unstable fracture with neurologic deficit, spinal instrumentation and fusion do nothing to enhance neural recovery but are done to provide anatomic spinal alignment and stability to allow early the patient mobilization and rehabilitation.
Accidents, Occupational ; Accidents, Traffic ; Bed Rest ; Braces ; Congenital Abnormalities ; Dissent and Disputes ; Humans ; Methods ; Neurologic Manifestations ; Rehabilitation ; Spinal Canal ; Spinal Fusion ; Spine ; Surgical Instruments ; Walking