Objective: To observe the clinical effect of acupuncture and hydro-acupuncture in treating anxiety. Methods: Compare between the therapeutic effect of 186 cases of Three Huang Points of DONG's extra points in treating anxiety and that of 139 cases by purely Western medicine buspirone. Results: The total effective rate of the treatment group was 91.4%, and the rate of the control group was 93.5%. There was statistical difference of Hamilton Anxiety Scale (HAMA) and Self Rating Anxiety Scale (SAS) scores before and after treatment in both groups (P＜0.001), while there was no statistical difference between the two groups (P>0.05). Conclusion: Acupuncture treatment compared favorably to anti-anxiety drug buspirone. Oral administration of buspirone had different degrees of side effects, such as dizziness, dry mouth, constipation, difficulty urinating and acidophilus, while there was basically no side effects of acupuncture and the effect of acupuncture was better than buspirone. This was especially suitable for patients who could not take medications for various reasons.

OBJECTIVETo explore the objective evaluation index of acupuncture effect through study on the differences of surface electromyography of deltoid before and after acupuncture at some specific points.

METHODSTwenty-six cases of periarthritis were treated with acupuncture at Jianyu (LI 15), Jianqian (Extra), Jianliao (TE 14) and Binao (LI 14). The treatment was given once every other day, six treatments were required. The deltoid myoelectricity indices were collected and analyzed before treatment, after treatment and after 5 s manipulations at each acupoint.

RESULTSCompared with the deltoid myoelectricity before treatment, there were statistically significant differences in the 2nd, 3rd and 5th manipulations during the acupuncture stimulation at Jianqian (Extra), the 2nd, 3rd and 6th manipulations at Binao ( LI 14) (all P < 0.05) and all the 6 manipulations at Jianyu (LI 15) (all P < 0.05). However, there was no statistically significant difference in all the 6 manipulations at Jianliao (TE 14) (all P > 0.05). And the differences of deltoid surface myoelectricity before and after the 6 acupuncture treatments were all with statistic significance (all P < 0.05).

CONCLUSIONA certain therapeutic effect can be found in treatment of periarthritis with acupuncture. And the effect at Jianyu (LI 15) is proved to be the most obvious. Jianqian (Extra) and Binao (LI 14) are considered as the second obvious. While no significant effect can be found at Jianliao (TE 14).

Acupuncture Points ; Acupuncture Therapy ; Adult ; Aged ; Electromyography ; Electrophysiology ; Female ; Humans ; Male ; Middle Aged ; Periarthritis ; physiopathology ; therapy

OBJECTIVE:To study the tissue distribution and liver-targeting activity of bifendate solid lipid nanoparticles (DDB-SLN) in mice.METHODS:A total of 60 mice were injected with DDB-SLN or DDB solution (DDBS) with DDB dosage at 20 mg?kg-1.Sampling was scheduled at 0.083,0.25,1,3 and 5 hours,and HPLC was employed to determine and compute the concentrations of DDB in plasma,heart,liver,spleen,lung,kidney and brain as well as the Drug Targeting Index (DTI) and the Drug Selecting Index (DSI) of DDB-SLN on DDBS.RESUTLS:The DDB concentrations in liver were the highest for both groups.At 0.25,1,3 and 5 h,the DDB concentrations in liver in DDB-SLN group were 1.15,3.04,2.72 and 3.62 times those in DDBS group.The DTI of DDB-SLN were 1.151,3.038,2.720 and 3.622,respectively and the DSI were 3.269,7.891,5.948 and 7.759,respectively.CONCLUSION:As compared with DDBS,DDB-SLN is a more potent liver-targeting drug.

Arthroplasty, Replacement, Hip ; Bone Transplantation ; Femur ; surgery ; Hip Dislocation, Congenital ; diagnosis ; surgery ; Humans

Objective To investigate the expression,and biological significance of uPA and Cath-D in early diagnosis of cervix carcinoma and cervical intraepithelial neoplasia.Methods The immunohistochemical SP was used to detect the expression of uPA and Cath-D proteins in 39 CA.ges with cervix carcinoma and 33 ofpatients with CIN cases and 15 cases with normal cervical epithelia.Results Positive rates of uPA and Cath-D in the cervix carcinoma were significantly higher than in the CIN.Positive rates of uPA and Cath-D in the CIN and the cervix carcinoma were significantly higher than in the normal cervical epithelia. The difference had statistical significance( P＜0. 05 ). In the group of CIN Ⅰ/CIN Ⅱ/CINⅢ ,the expression of uPA and Cath-D had significant diffcrence(P ＜0. 05). In the group of highly, moderate and lowly developed tissue, the expression of uPA and Cath-D had significant difference (P＜0. 05). In the group with and without LNM, the expression of uPA and Cath-D had significant difference( P＜0. 01 ).Conclusions uPA and Cath-D may involve in the initiation of CIN, cervix carcinoma, uPA and Cath-D could be used as markers for early diagnosis of cervix carcinoma. It could be helpful for increasing the ratio of earlier diagnosis in the fields of cervix carcinoma.

Objective To discuss the efficacy of oxygen blow atomization inspiration ambroxo in treat-ing capillary bronchitis. Methods From Oct 2005 to Dec 2007, 108 infants with capillary bronchitis from the Central Hospital were divided into three groups, i. e. Group A, Group B and Group C, to which normal thera-peutic methods are applied. However, Group A adopted oxygen blow atomization inspiration ambroxo, twice a day;Group B applied Intravenous Injection of Ambroxo, twice a day; while Group C was treated with Oral Ambroxo, twice a day. After 5 days of treatment, compare clinical symptoms, pulmonary signs, hospitalization days and total effective rate of the three groups. Results Group A succeeded in significantly improving its cure rate, eliminating symptoms like cough, asthma, dyspnea and wheezing sound and moist tales, and considerably reducing days in hospital. This group features its significant difference from Group B and Group C (P <0.01).Conclusion in treating capillary bronchitis, Oxygen blow atomization inspiration ambroxo can reduce course of disease, improve cure rate, and it is a therapeutic method with outstanding curative effects and easy to apply.

Acetabulum ; surgery ; Arthroplasty, Replacement, Hip ; Femur ; surgery ; Humans ; Reoperation

90% by MTT assay,in vivo experiment tumor weight inhibition rates were93.514 4,90.719 2,96.592 3respectivly. Conclusion:Embelin was good for cells SGC7901,especial for a low dose combination with VCR.

Objective:To evaluate the experience in the surgical treatment of the elderly patients with cholelithiasis.Methods:136 patients with cholelithiasis were retrospectively studied.Results:All patients underwent opertion.118 cases recurred(86.7%),and 4 cases died(3.85%).65 cases underwent cholecystectomy,while 36 cases underwent cholecystectomy plus exploration of common bile duct.25 cases were performed with exploration of common bile duct,and 7 cases underwent choledochostomy plus drain.In addition,3 cases underwent cholecystostomy.Conclusion:The characteristics are atypical manifestation,predispose to delay the diagnosis,more associasion with chronic disease.However,the age is no contraindication of operation.The satisfactory results can be achieved granted the indication and time for the operation are selected properly,and the management of the perioperative period is much concerned as well as the easy-going effective way of the operation is taken.

Objective To investigate the pathological characteristics and clinical significance of ultrasructure in lung tissues of type 2 diabetic adult patients.Methods Normal lung tissues far from lung neoplasm in 10 cases of type 2 diabetic patients associated with lung cancer were observed under a transmission electron microscope. Results Type Ⅱ alveolar cells became small,and cell superficial microvilli disappeared,Osmiophilic lamellar body became atrophy,lacked lamellar structure and formed a solid globule with high electrom dense;Rough endoplasmic reticulum and mitochodria in cytoplasm were enlarged cystiformly,and there were translucent materials deposited in vesicle,euchromatin decreased,heterochromatin condensed;The basement membrane of bronchial capillary were diffusely thickened and mostly showed onion-skin like change,protein deposited around and mixed with basement membrane.Conclusion Lung is confirmed to be the target organ of chronic damage in diabetes.Pathological changes of pulmonary tissues induced by diabetes have its specific characteristics,which are different from other pulmonary diseases.These changes are pathological basis of pulmonary function abnormalities.