Trminal ileum and cecum are the most frequently involved portions of the gastrointestinal tract in Behqet's disease. Esophageal involvement in Behqet's disease is very uncommon and only a few cases have previously been reported. We have observed a case with this disease. A 25-year-old female patient who was diagnosed as having Behqet's disease 7 years before had dysphagia and weight loss of about 10 kg for 4 months. Esophagogastroduodenoscopic examination revealed diffuse ulceration and mucosal nodularities in esophagus which suspected esophageal cancer. But repeated biopsies showed lymphocytic infiltration around vessels in ulcerative lesions. She was treated with conservative managements.
Adult ; Biopsy ; Cecum ; Deglutition Disorders ; Esophageal Neoplasms ; Esophagus ; Female ; Gastrointestinal Tract ; Humans ; Ileum ; Ulcer* ; Weight Loss

OBJECTIVE: The purpose of this study was to evaluate the difference for each variable on plain radiologic study of the foot between weighted and non-weighted routine plain anterior-posterior and lateral views in flatfoot children diagnosed by Harris mat footprint. METHOD: Both feet of thirty-four children over two-year old, who had been diagnosed as flatfooted by modified Rose' classification using Harris mat footprint were included. We studied plain roentgenogram images, including anterior-posterior and lateral views, in both standing (weighted) and sitting (non weighted) position of the feet of the patients. We measured the following variables; arch height (AH), calcaneal pitch (CP), talocalcaneal angles from lateral view (TCALA) and anterior-posterior view (TCAAP), talo-first metatarsal angles from the lateral (TFML) and anterior-posterior view (TFMA). RESULTS: Each variable revealed no significant difference between boys and girls (p>0.05); neither was there any significant difference noted in each parameter between the right and left feet (p>0.05). All the variables of plain foot roentgenogram on weighted state were significantly different from the data of non-weighted state, except TCAAP (p<0.05). CP was the only parameter which showed significant difference according to severity of flatfoot by modified Rose'classification. CONCLUSION: Because most of the flatfoot in childhood is hypermobile type, it is necessary to take plain radiologic studies of the feet both in weighted and non weighted state and to compare both data of each variable. In addition, it is prefer to use plain radiologic study of foot both in weighted and non weighted state with footprint as the screening method of pediatric flatfoot lesions.
Child ; Classification ; Female ; Flatfoot* ; Foot ; Humans ; Mass Screening ; Metatarsal Bones ; Radiography

Partial hand amputation may leave a significant functional limitations for amputee that are difficult to ameliorate by either orthoses or prostheses. Many kinds of devices have been tried to promote the function and cosmesis. Cosmetic hand was the best answer to the person with first and second metacarpophalangeal joint disarticulation and the strength and range of motion of remaining three fingers were not in optimal status till now. We applied a new device of wrist driven prehension prosthesis consist of forearm stabilizer, short opponens, actuator rod, artificial thumb, artificial index and attached 2 rings was designed and fabricated. As a result, it is possible to provide considerable improvement in function and cosmesis with this new device.
Amputation* ; Amputees ; Disarticulation ; Fingers ; Forearm ; Hand* ; Humans ; Metacarpophalangeal Joint ; Orthotic Devices ; Prostheses and Implants* ; Range of Motion, Articular ; Rehabilitation* ; Thumb ; Wrist*

Circumcaval ureter is one of the congenital anomaly in which aberrant development of the inferior vena cava (IVC) causes compression of the deviated ureter medially behind the IVC. The incidence is approximately one in 1500 cadavers and is three to four times more common in male. Although the lesion is congenital, symptoms attributable to this anomaly usually appear in young adulthood. This is a case of 17-year-old spinal cord injured man with a circumcaval ureter who was diagnosed as right hydronephrosis by routine evaluation for neurogenic bladder, incidentally. Suprapubic cystostomy was done for prevention of further urologic complication and the severity of hydronephrosis was not aggravated in follow up studies after 6 months. We suggest early routine evaluation for neurogenic bladder is very important for prevention of developing urologic complication caused by congenital urologic anomaly in the patients with spinal cord injury.
Adolescent ; Cadaver ; Cystostomy ; Follow-Up Studies ; Humans ; Hydronephrosis* ; Incidence ; Male ; Retrocaval Ureter* ; Spinal Cord Injuries ; Spinal Cord* ; Ureter ; Urinary Bladder, Neurogenic ; Vena Cava, Inferior

OBJECTIVE: To evaluate the changes of motor unit number estimation (MUNE) and the amplitude of compound muscle action potential (CMAP) according to severity of nerve injury in rat. METHOD: The sciatic nerve was compressed with two different severity (mild, severe) in 20 rats each. MUNE was performed in gastrocnemius of rat using the Poisson statistics. MUNE and amplitude of CMAP were compared according to severity of injury at two and four weeks after injury. RESULTS: The MUNE and amplitude of CMAP were significantly diminished at two and four weeks after nerve injury in severely injured rat. Both values were also diminished at two weeks after injury in mildly injured rat. The amplitude of CMAP was slightly increased at four weeks after mild injury despite of further decrement of MUNE. CONCLUSION: The MUNE and amplitude of CMAP changed differently according to severity of nerve injury in rat, which might represent different denervation and reinnervation process.
Action Potentials ; Animals ; Denervation ; Peripheral Nerve Injuries* ; Peripheral Nerves* ; Rats* ; Regeneration ; Sciatic Nerve

BACKGROUND/AIMS: Endoscopic submucosal dissection (ESD) is not commonly used in the colorectal area because of technical difficulty and due to the characteristics of the organ. We therefore wanted to determine the efficacy and safety of endoscopic submucosal dissection in colorectal neoplasms. METHODS: Colorectal tumor lesions resected by ESD in a single medical center were analyzed retrospectively. RESULTS: A total of 47 patients were treated for 50 lesions. Mean age was 64.3+/-9.8 (43~85) years. Laterally spreading tumors were the most common type (44, 88%) followed by Is+IIa type tumors (6, 12%). The en bloc resection rate was 76% and the complete resection rate was 74%. The mean procedure time was 81.1+/-44.7 (20~180) minutes. The mean size of resected specimen was 26.9+/-10.4 (10~50) mm. The histological diagnosis determined that 24 lesions (48%) were tubular adenoma, 18 lesions (36%) were intramucosal cancer, 7 lesions (14%) were sm1 cancer and 1 lesion (2%) was over sm2 cancer. Bleeding occurred in 6 (12%) and perforations in 13 (26%) of the patients and all were treated successfully by endoscopic or conservative treatment. The concordance rate of pre and post ESD pathological diagnosis was only 47%. CONCLUSIONS: ESD is a feasible technique for treating superficial colorectal tumors with a high complete resection rate, minor invasiveness, and a high safety rate. In addition, ESD might be useful in establishing the complete pathological evaluation of colorectal epithelial neoplasm.
Adenoma ; Colorectal Neoplasms ; Hemorrhage ; Humans ; Neoplasms, Glandular and Epithelial ; Retrospective Studies

BACKGROUND/AIMS: Endoscopic Mucosal Resection (EMR) and Endoscopic Submucosal Dissection (ESD) are novel techniques used for the treatment of early gastric cancer and precancerous lesions of the stomach. However, complications such as bleeding and perforation may occur during the procedure, and these complications may raise the morbidity and mortality rates. EMR/ESD-induced perforations can be treated with conservative medical or non-surgical methods. Furthermore, an increasing number of reports have addressed conservative management of EMR/ESD-induced perforations. We evaluated the effectiveness and safety of implementing conservative treatment for perforations associated with EMR and ESD. METHODS: We reviewed 482 patients with 507 lesions who underwent EMR or ESD due to early gastric cancers or gastric adenomas between February 2003 and December 2007. We identified 14 perforations occurring as complications of EMR/ESD and investigated their clinical outcomes. RESULTS: Fourteen perforations (14/507 [2.8%]) occurred, 11 of which were immediately clipped during the procedure, and 3 of which were diagnosed after the procedure when free air was visualized on the radiograph. All patients were managed conservatively with fluid resuscitation and antibiotics (mean, 5.8 days). They recovered without surgery and were discharged in stable condition at a mean of 7.2 days post-procedure. CONCLUSIONS: Endoscopic clip application might be an effective and safe option for conservative management of EMR/ESD-induced perforations.
Adenoma ; Anti-Bacterial Agents ; Hemorrhage ; Humans ; Resuscitation ; Stomach ; Stomach Neoplasms

Post-radiation soft tissue sarcomas are recognized as rare complications of radiation therapy. The most common type of post-radiation soft tissue sarcoma is a malignant fibrous histiocytoma (MFH), which originates from mesenchymal cells with a predominance of histiocytes and fibroblasts. The two most common sites of occurrence for post-radiation soft tissue sarcomas are the chest wall and pelvic cavity. Post-radiation colorectal MFHs are extremely rare and all of the reported cases of post-radiation sarcomas have occurred >3 years after radiation therapy. Recently, we managed a case of colorectal MFH which developed in a 48-year-old male who had undergone a low anterior resection for rectal adenocarcinoma and had received chemoradiotherapy as adjuvant treatment. Twelve months after radiotherapy, a 4 cm mass was detected 8 cm superior to the anastomosis site on colonoscopic examination. A soft tissue sarcoma was suspected on pathologic examination of the biopsy specimen. Therefore, he underwent a Hartmann's operation and the final pathologic finding revealed MFH with a storiform pattern of tumor cells composed of pleomorphic, multinucleated giant cells. This is the first case of MFH that had a latency period <3 years (i.e., 1 year) between the time of radiotherapy and diagnosis.
Adenocarcinoma ; Biopsy ; Chemoradiotherapy ; Fibroblasts ; Giant Cells ; Histiocytes ; Histiocytoma, Malignant Fibrous ; Humans ; Latency Period (Psychology) ; Male ; Middle Aged ; Sarcoma ; Thoracic Wall

Post-radiation soft tissue sarcomas are recognized as rare complications of radiation therapy. The most common type of post-radiation soft tissue sarcoma is a malignant fibrous histiocytoma (MFH), which originates from mesenchymal cells with a predominance of histiocytes and fibroblasts. The two most common sites of occurrence for post-radiation soft tissue sarcomas are the chest wall and pelvic cavity. Post-radiation colorectal MFHs are extremely rare and all of the reported cases of post-radiation sarcomas have occurred >3 years after radiation therapy. Recently, we managed a case of colorectal MFH which developed in a 48-year-old male who had undergone a low anterior resection for rectal adenocarcinoma and had received chemoradiotherapy as adjuvant treatment. Twelve months after radiotherapy, a 4 cm mass was detected 8 cm superior to the anastomosis site on colonoscopic examination. A soft tissue sarcoma was suspected on pathologic examination of the biopsy specimen. Therefore, he underwent a Hartmann's operation and the final pathologic finding revealed MFH with a storiform pattern of tumor cells composed of pleomorphic, multinucleated giant cells. This is the first case of MFH that had a latency period <3 years (i.e., 1 year) between the time of radiotherapy and diagnosis.
Adenocarcinoma ; Biopsy ; Chemoradiotherapy ; Fibroblasts ; Giant Cells ; Histiocytes ; Histiocytoma, Malignant Fibrous ; Humans ; Latency Period (Psychology) ; Male ; Middle Aged ; Sarcoma ; Thoracic Wall