INTRODUCTIONSplenic abscess is an uncommon clinical problem. Traditionally, the "gold standard" treatment has been splenectomy. However, there is increasing use of non-operative treatments worldwide.

MATERIALS AND METHODSA 10-year (1996-2005) retrospective review of case records from a single centre (an 800-bed general hospital) was performed. Information regarding demographics, clinical presentation, aetiological agents and management was gathered and analysed.

RESULTSThere were 21 cases from 1996 to 2005. Nineteen (90%) had multiple abscesses. Disseminated melioidosis was the most common aetiological agent (15 cases, 71%). Only 3 patients underwent splenectomy. The remainder were treated conservatively with antibiotics. Almost all the patients (19, 90%) also suffered from diabetes mellitus.

CONCLUSIONSThe most common aetiological agent encountered was Burkholderia pseudomallei. Diabetes mellitus may be an important co-factor in the pathogenesis of splenic abscesses. The majority of our patients were managed conservatively and splenectomy was only occasionally required.

Abscess ; drug therapy ; epidemiology ; etiology ; Adult ; Aged ; Anti-Bacterial Agents ; therapeutic use ; Bacteremia ; complications ; drug therapy ; Female ; Hospitals, General ; statistics & numerical data ; Humans ; Male ; Melioidosis ; complications ; epidemiology ; Middle Aged ; Retrospective Studies ; Singapore ; epidemiology ; Splenic Diseases ; drug therapy ; epidemiology ; etiology