2.CONSTRUCTION AND APPLICATION OF WEB-BASED COURSEWARE OF INDUSTRIAL MICROBIOLOGY
Jin CAI ; De-Cheng QIU ; Hong CHAI ;
Microbiology 1992;0(06):-
Industrial Microbiology is a stem course in the undergraduate and graduate education of Biological Engineering major; and the research and development on computer -aided education in biological fields is just at the beginning stage in China. This paper focuses on the construction and application of web-based courseware for teaching and studying of industrial microbiology.
3.A signal analysis method for bioelectrical impedance measurement of gastric motility based on HHT
Linyan CHAI ; Shu ZHAO ; Hong SHA
International Journal of Biomedical Engineering 2011;34(2):82-85
Objective The Hilbert- Huang transformation (HHT) method was introduced to process the bio-impedance gastric motility signals from subjects.Methods Nonlinear and non-stationary original gastric motility series were decomposed into a number of intrinsic mode function (1MF) components by the empirical mode decomposition method (EMD).Hilbert transformation was carried out then and instantaneous frequency was extracted effectively.Gastric motility signal among 0.03-0.06 Hz was reconstructed from the IMF.Results The results suggested that HHT was a new and applicable time series analysis method based on mode decomposition and could extract impedance signal and remove the disturbances such as blood flow and breathing.Conclusion The new adaptive mode decomposition-based signal processing method provides a new method to investigate clinical gastric motility information.
4.Prospective study on the rapid exchange biliary system for therapeutic ERC
Enqiang LINGHU ; Ningli CHAI ; Hong DU
Chinese Journal of Practical Internal Medicine 2006;0(16):-
Objective The study intends to evaluate the extent to which the rapid exchange biliary system(RX system)provides improved efficiency in comparison with conventional guide wire combinations during therapeutic endoscopic retrograde cholangiopancreatography(ERCP).Methods A prospective study was carried out in which 213 patients were randomized to undergo traditional devices(106 patients)or RX system(107 patients).The parameters were recorded in every case,including the wire loss rates,catheter/guide wire exchange times and fluoroscopy times.Results Wires accessing to the desired ductal/strictures were achieved in 97.1% of conventional devices group and 98.1% of RX system group.But in the conventional devices group,the wire loss rates(%)were significantly higher than the rates in RX system group(10.2?2.3 vs 2.4?1.2,P
5.The study on the application of rapid exchange biliary system for calculus of bile duct removed cases.
Enqiang LINHU ; Ningli CHAI ; Hong DU
Chinese Journal of Practical Internal Medicine 2006;0(18):-
Objective To evaluate the application of RX rapid exchange biliary system in(endoscopic retrograde cholangiopancreatography,ERCP)treatment for patients with bile duct stone.Methods 154 patients were divided into traditional devices group(76 cases)or RX system group(78 cases)according to the size of bile duct stone and state of patients randomizly,then guide wire loss rates,catheter/guide wire exchange times and easy degree of buskets and ballons inserted to bile duct was recorded respectively during procedure,all parameters was analyized by Chi-square methods or t test.Results The guide wire loss rates(%) of RX group was obviously lower than that of traditional devices group(2.2?1.4 vs 9.5?2.8,P0.05).Conclusion RX system is shorten the time and convenience the operation in ERCP for treating patients with common bile duct stone,as well as improve the therapy efficiency.
6.Predictive value of antithyroglobulin antibody on recurrence or metastasis following ablation in differentiated thyroid carcinoma
Hong CHAI ; Zequan CHEN ; Yongli YU
Chinese Journal of Endocrinology and Metabolism 2014;30(4):292-296
Objective To investigate the value of serum thyroglobulin (Tg) and antithyroglobulin antibody (TgAb) in differentiated thyroid carcinoma complicated with Hashimoto's thyroiditis after thyroid ablation.Methods Serum Tg and TgAb levels and the status of illness in 154 differentiated thyroid carcinoma patients with coexistent Hashimoto's thyroiditis and confirmed pathology after surgery followed by remnant ablation were performed during three years follow up.Tg and TgAb levels were assessed by chemiluminescent immunoassay assay.The cases were divided into three groups (according to the level of Tg):Tg ≤ 1 μg/L group,1 μg/L<Tg ≤ 10 μg/L group and 10 μg/L<Tg≤ 100 μg/L group.TgAb>40 kIU/L was considered as positive,Cox's proportional hazard model was used to analyse prognostic value in different levels of Tg and TgAb for disease-free survival and recurrence.Results Compared with 1 μg/L<Tg≤ 10 μg/L group and 10 μg/L<Tg≤ 100 μg/L group,the relative risk in reflecting cancer recurrence (TgAb>40 kIU/L) in Tg ≤ 1 μg/L group was 27.000 (95 % CI 6.727-108.374).The value of TgAb>40 kIU/L in Tg≤ 1 μg/L group was greatly increased and highly correlated with metastasis.However,In the condition of Tg> 1 μg/L,the disease will be based on the level of TgAb.Conclusion The value of TgAb>40 kIU/L in Tg ≤ 1 μg/L group seems to be the optimal cutoff value correlated with recurrence and metastasis of differentiated thyroid carcinoma.
7.Carcinoma In Situ of the Urinary Bladder with Transitional Cell Carcinoma of Prostate: A Histopathologic Study and Mapping of the Urothelial Lesions.
Seung Pyo HONG ; Sang Sook LEE ; Chai Hong CHUNG
Korean Journal of Pathology 1987;21(3):199-206
A 63-year-old male patient with extensive carcinoma in situ of the urinary bladder was found to have unsuspected transitional cell carcinoma of the prostate. Mapping of the totally embedded radical cystectomy specimen demonstrated diffuse, multifocal, epithelial abnormalities, ranging from mucosal atypia to the nonpapillary carcinoma in situ with extension to the urethra, prostatic ducts and glands, seminal vesicles and ureter, probably reflecting individual urothelial susceptibility in reaction to carcinogenic stimulus. The importance of prostatic assessment in the evaluation of the patient with carcinoma in situ of the urinary bladder is emphasized.
Male
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Humans
8.Immunohistochemical Demonstration of Fibronectin in Paraquat-Induced Interstitial Fibrosis of Adult Human Lung.
Seung Pyo HONG ; Sang Sook LEE ; Chai Hong CHUNG
Korean Journal of Pathology 1987;21(3):138-143
We studied distribution of fibronectin in paraquat-induced adult fibrotic lung by indirect immunofluorescence and indirect immunoperoxidase methods, using affinity-purified antifibronectin IgG peroxidase conjugates and antifibronectin IgG FITC conjugates. In contrast to the relative paucity of staining in normal lung, there was a marked increase in interstitial staining for fibronectin in this fibrotic lung. This marked alterations in the apparent amounts and distribution of fibronectin in fibrotic human lung suggest its involvement in the cellular events accompanying human lung fibrosis.
Adult
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Male
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Female
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Humans
9.Classification of Gallstones and their Characteristics.
Sang Sook LEE ; Eun Sook CHANG ; Chai Hong CHUNG
Korean Journal of Pathology 1986;20(2):157-164
Total 481 cases of gallstones from Korean patients operated at Keimyung University Dongsan Hospital during the last 6 years were classified by macroscopic view according to the classification of Sato, et al and reviewed with a special reference to age, sex, and kinds and sites of gallstones. Gallstrones were present predominatly in the age of 50-60 years, the average 52. Sex ratio (M:F) was nearly equal, being 1:1.05. Gallbladder was the most frequent site, comprising 53.2%, followed by common bile duct, 23.3% and intrahepatic location, 3.7%. Macroscopic classification revealed pigment gallstones in 53.0% (calcium bilirubinate, 41.8%; black, 11.2%); cholesterol gallstones in 36.2%, of which mixed stone being 33.1%. Cholesterol gallstones occurred predominantly in 50-60 years of age with a prediletion to females. On the contrary, elderly persons more than 60 years of age had calciu bilirubinate stones. No sex difference was found in the calcium bilirubinate stones. Eightly-six percent of cholesterol gallstones were present in the gallbladder only. Common bile duct stones were mostly composed of pigment gallstones in 80.4%.
Female
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Humans
10.Immunohistochemical Application of Leukocyte Common Antigen and Epithelial Membrane Antigen in the Diagnosis of Large Cell Undifferentiated Tumors.
Chan Hwan KIM ; Sang Sook LEE ; Chai Hong CHUNG
Korean Journal of Pathology 1988;22(3):215-221
A total of 42 cases undifferentiated large cell tumors were stained by immunoperoxidase techniques using antibodies against leukocyte common antigen (LCA) and epithelial membrane antigen (EMA). In 18 of the 21 cases studied, initially diagnosed as malignant lymphoma or Hodgkin's disease, reactivity with monoclonal anti-LCA (and noreactivity with monoclonal anti-EMA)indicated that the tumor was a lymphomas. The remaining 3 cases gave the reverse reaction pattern and therefore were classified as carcinoma. One out of 16 cases diagnosed as undifferentiated carcinoma proved to be a case of mialignant lymphoma in 5 patients in whom the original diagnosis was uncertain, a definite diagnosis was possible in all cases and 3 of these proved to be large cell lymphoma; the remainders, undifferentiated carcinoma. It is suggested that the staining of undifferentiated human neoplasms using combinations of antibodies reactive with epithelial and lymphoid cells may result in much greater diagnostic accuracy.
Humans