A clinical study including physical examination, electromyographic and roentgenological studies of the 2. Taekwondoists hands who mainly practiced the object-breaking maneuver with a hand who were cared at the department of orthopedic surgery, Hanyang University Hospital from November 1, 1981 to January 31, 1982, The results of the survey were as follows. 1. The average age of the athletes was 26.7 years, the average Taekwondo-practicing career was 9.7 years, the average object breaking career was 6.4 years, and the startmg age of breaking was 20.1 years in average. 2. The main parts of the hand for the breaking were Joomeok(fist) and Sonnal (ulnar edge of the palm; hand knife). 3. Bricks and tiles were commonly used as materials for breaking. Seventeen(74%) athletes could break 1 to 2 layers brick blocks, and twenty(87%) could break the 10 to 15 layers roof-tile blocks. 4. Twelve (52.1%) athletes got injuries during breaking practice. The most common injury was metacarpal fracture (7/14, 58.5%), dislocation (2/14, 16.7'lo), subluxation, sprain, and contusion (1 each/14, 8.3%) were less frequent. 5. The thickness of the knuckle pad varied from 2 to 3.9mm in 16/23 (69.5%). The average grasping power of the athletes was 97.6 1bs, and it was stronger than normal person by 9.3 lbs. 6. The electromyographic study showed no isgnificant difference in nerve conduction velocity between the af- fected and unaffected hands, which was within the normal range. It was found that the muscle primarily used was flexor digitorum profundus. 7. In the roentgenological study, the length of the second metacarpal on the affected side was the same or 0 tc 2mm shorter than the unaffected side, and when the athlete was in the growth period, the metacarpal short ness was more marked. 8. Roentgenologically no hypertrophy of the metacarpal and phalangeal bones noted.
Athletes ; Clinical Study ; Contusions ; Dislocations ; Hand Strength ; Hand ; Humans ; Hypertrophy ; Neural Conduction ; Orthopedics ; Physical Examination ; Reference Values ; Sprains and Strains

Nitric oxide ( NO ) is now recognized as a mediator of several biological and immunological functions, but unlike classical neurotransmitters, NO simply diffuse of the postsynaptic cell and around affecting cells. Human chorionic gonadotropin ( hCG ), produced by placental trophoblasts may act as stimulator on NO synthesis in oocytes of mouse's ovary. How-ever, in the various organs or cells, the action of hCG on NO synthesis is unknown. We have examined that the effect of hCG on NO synthesis in microglial cells of murine's brain, using the Griess method. And this study was evident that hCG did not induce NO produc-tion without recombinant interferon gamma ( rIFN-gamma), whereas hCG ( 10~500 IU/ml ) with rIFN-gamma effectively produced NO in microglial cells of brain. As result, NO production in microglial cells increased most significantly in dose of 100 IU/ml of the hCG and the pro-duction of NO was dependent on the dose of hCG ( Table 1 and Fig. 1 ). And N(G)-monomethyl-L-arginine ( N(G)MMA ), competitive inhibitor of NO synthase, reduced the NO production by hCG stimulation with rIFN-gamma in microglial cells of murine. Conclusively, this study sugge-sted that hCG stimulate NO production at microglial cells in brain, which may be an important factor for mediating immune and neuroendocrinologic regulation in nervous system.
Brain ; Chorionic Gonadotropin* ; Female ; Humans* ; Interferons ; Negotiating ; Nervous System ; Neurotransmitter Agents ; Nitric Oxide Synthase ; Nitric Oxide* ; Oocytes ; Ovary ; Trophoblasts

No abstract available.

The congenital dislocation of the hip is one of the most common congenital disease in the field of the orthopedic surgery. For the normal development of the acetabulum and femoral head, the displaced femoral head shouid be replaced in the acetabular socket as early as possible. In most cases treated in proper time, closed reduction is successful. If not, operative correction will almost always be necessary due to abnormal changes of the acetabulum and femoral head. We experienced 33 cases in 32 patients of the congenital dislocation of the hip at the Department of Orthopedic Surgery of Hanyang University Hospital from May, 1972 to December, 1980. The results obtained were as follows: 1. The most common aged group at the first visit was ranged from 12 months to 24 months and the preponderance of girl to boy was 3.6:1. 2. The ratio of left to right side was 1.6:1. 3. In delivery history, there were 3 cases of breech presentation, 1 case of Cesarean section and 1 case of prematurity. The associated congenital anomaly was observed in a case of which combined internal tibial torsion and talipes metatarsus varus deformity. 4. In 33 cases in 32 patients, 22 cases were treated conservatively and 11 cases were treated surgically. The results of treatment were excellent in 21 cases, good in 11 cases and fair in 11 case. We experienced 4 cases of neglected congenital dislocation of the hip in the period of late childhood, 3 cases were treated with Chiari osteotomy and the other 1 case was treated with Colonna capsular arthroplasty. The overall results were excellent.
Acetabulum ; Arthroplasty ; Breech Presentation ; Cesarean Section ; Clinical Study ; Clubfoot ; Congenital Abnormalities ; Dislocations ; Female ; Head ; Hip ; Humans ; Male ; Metatarsus ; Orthopedics ; Osteotomy ; Pregnancy

No abstract available.
Animals ; Atrophy* ; Electric Stimulation* ; Muscle, Skeletal* ; Rats* ; Sciatic Nerve*

No abstract available.
Humans ; Osteosarcoma*

BACKGROUND: Endocrine pancreas tumor is a rare disease which incidence is less than 2% of all pancreatic tumors. But it comprises various types of tumor and usually secretes several hormones from one type of tumor although the patient with this tumor complains of sole symptom associated with only one hormone. The mechanism and clinical significance of multiple hormone secretion in the endocrine pancreas tumom are not yet clearly defined. METHODS: We analyzed retrospectively the clinicopathologic features of 20 cases which were operated at Seoul National University Hospital during the period between February 1989 and May 1998. RESULTS: The most common tumor was insulinoma (13 cases) and the second most common tumor was nonfunctioning tumor (6 cases). There was one case of somatostatinoma. Most of the patients with insulinoma complained of neuroglycopenic symptoms. There were 9 cases (45.0%) in which the tumors secreted more than two kinds of hormones, 7 cases in insulinoma, 2 cases in nonfunctioning tumors. Whether the tumor secreted multiple hormones was detected by the method of immunohistochemical staining. Though the tumors secreted more than two kinds of hormones, the patients with the tumors complained of symptoms which were associated with the cell type most strongly stained by immunohistochemical method. Whether or not the tumors secreted multiple hormones was not associated with the pathologic features such as tumor size, histologic patterns of the tumor, status of tumor cell differentiation and malignancy. CONCLUSION: From this results, we suggest that endocrine tumors of the pancreas secreted multiple hormones not by the mechanism of dedifferentiation from already differentiated endocrine cells but by the mechanism of neogenesis of multipotent islet stem cells. Since the relationship between the function of multiple hormone secretion in the endocrine pancreas tumors and islet stem cell would be significant, further study should be needed to find out the function of stem cells and application of stem cells to clinical use.
Cell Differentiation ; Endocrine Cells ; Humans ; Incidence ; Insulinoma ; Islets of Langerhans ; Pancreas* ; Rare Diseases ; Retrospective Studies ; Seoul ; Somatostatinoma ; Stem Cells

Despite early knowledge that autogenous nerve grafting can be a useful method to overcome large gaps in peripheral nerves, the procedure was generally resorted to only after all other means to obtained end-to-end suturing had failed. Advances in microsurgery techniques prompted Millesi to introduce the concept of interfascicular neve grafting whereby groups of fascicles, and not whole nerve, are connected together. The 17 cases of nerve graft were operated for 3 years from Nevember, 1982 to September, 1985 in the Department of Orthopaedic Surgery of Hanyang University Hospital have followed for clinical up study. The results were as follows: 1. Nerve graft was useful rnethod to repair nerves with gaps. 2. The sural nerve is the first choice as a donor nerve. 3. Severity of soft tissue injuries was important factor influencing results. 4. Postoperative results of cases caused by electrical burns were worse than others.
Burns ; Clinical Study ; Health Resorts ; Humans ; Methods ; Microsurgery ; Peripheral Nerves ; Soft Tissue Injuries ; Sural Nerve ; Tissue Donors ; Transplants

Sprengels deformity is a relatively uncommon congenital deformity. Since first described by Eulenberg in 1863, many authors have reported this abnormal condition and many surgical approaches have been devised. In this case, an eight year old boy had a relatively marked deformity with motion limitation of the Lt. shoulder joint especially abduction. Surgical correction was performed by the Green method in which method in which sevral muscles were dissected from the scapula extraperiosteally, the supraspinous part of the scapula was resected along with its periostem, one omovertebral bone which articulated between the superomedial angle of the scapula and the Tl transverse process was excised, the scapula was moved down by wire traction to a normal position. Postoperative results were relatively good cosmetically and functional improvement was achieved.
Congenital Abnormalities ; Humans ; Male ; Methods ; Muscles ; Scapula ; Shoulder Joint ; Traction

Synovial sarcoma is an uncommon, malignant tumor which originates from the synovial lining of the joints, bursae and tendon sheaths. But it rarely occurs from bones. We have experienced a synovial sarcoma of the left ulna. Microscopically cleft spaces lined by epithelioid cells and bundle formation by spindle spaped cells were seen. Above elbow amputation of the left arm was done.
Amputation ; Arm ; Elbow ; Epithelioid Cells ; Joints ; Sarcoma, Synovial ; Tendons ; Ulna