2.Correlation between patient health questionnaire-2 and postoperative pain in laparoscopic cholecystectomy
Yusom SHIN ; Tae Woo PARK ; Huiyoung KIM ; Dong-jin SHIM ; Hochul LEE ; Joo-Duck KIM ; Donghee KANG
Anesthesia and Pain Medicine 2020;15(2):241-246
Background:
Postoperative pain is affected by preoperative depression. If the risk of postoperative pain associated with depression can be predicted preoperatively, anesthesiologists and/or surgeons can better manage it with personalized care. The objective of this study was to determine the efficacy of Patient Health Questionnaire-2 (PHQ-2) depression screening tool as a predictor of postoperative pain.
Methods:
A total of 50 patients scheduled for elective laparoscopic cholecystectomy with an American Society of Anesthesiologists grade of 1 or 2 were enrolled. They answered the PHQ-2, which consists of two questions, under the supervision of a researcher on the day before the surgery. The numerical rating scale (NRS) scores were assessed at post-anesthesia care unit (PACU), at 24, and 48 postoperative hours, and the amount of intravenous patient-controlled analgesia (IV-PCA) administered was documented at 24, 48, and 72 postoperative hours. At 72 h, the IV-PCA device was removed and the final dosage was recorded.
Results:
The NRS score in PACU was not significantly associated with the PHQ-2 score (correlation coefficients: 0.13 [P = 0.367]). However, the use of analgesics after surgery was higher in patients with PHQ-2 score of 3 or more (correlation coefficients: 0.33 [P = 0.018]).
Conclusions
We observed a correlation between the PHQ-2 score and postoperative pain. Therefore, PHQ-2 could be useful as a screening test for preoperative depression. Particularly, when 3 points were used as the cut-off score, the PHQ-2 score was associated with the dosage of analgesics, and the analgesic demand could be expected to be high with higher PHQ-2 scores.
3.Change of inspired oxygen concentration in low flow anesthesia
Jiwook KIM ; Donghee KANG ; Hochul LEE ; Sungwon RYU ; Siejeong RYU ; Doosik KIM
Anesthesia and Pain Medicine 2020;15(4):434-440
Background:
There are several advantages of low flow anesthesia including safety, economics, and eco-friendliness. However, oxygen concentration of fresh gas flow and inspired gas are large different in low flow anesthesia. This is a hurdle to access to low flow anesthesia. In this study, we aimed to investigate the change in inhaled oxygen concentration in low flow anesthesia using oxygen and medical air.
Methods:
A total of 60 patients scheduled for elective surgery with an American Society of Anesthesiologist physical status I or II were enrolled and randomly allocated into two groups. Group H: Fresh gas flow rate (FGF) 4 L/min (FiO₂ 0.5). Group L: FGF 1 L/min (FiO₂ 0.5). FGF was applied 4 L/min in initial phase (10 min) after intubation. After initial phase FGF was adjusted according to groups. FGF continued at the end of surgery. Oxygen and inhalation anesthetic gas concentration were recorded for 180 min at 15 min interval.
Results:
The inspired oxygen concentration decreased by 5.5% during the first 15 min in the group L. Inspired oxygen decreased by 1.5% during next 15 min. Inspired oxygen decreased by 1.4% for 30 to 60 min. The inspired oxygen of group L is 35.4 ± 4.0% in 180 min. The group H had little difference in inspired oxygen concentration over time and decreased by 1.8% for 180 min.
Conclusions
The inspired oxygen concentration is maintained at 30% or more for 180 min in patients under 90 kg. Despite some technical difficulties, low flow anesthesia may be considered.
4.A Case of T-Lymphoblastic Lymphoma/Leukemia with Bilateral Primary Adrenal Involvement.
Chul Min JUNG ; Seo Young SONG ; Sun Wook KIM ; Dong Hyun LEE ; Hochul JUNG ; Ho Jin LEE ; Youngjoon RYU
Korean Journal of Medicine 2014;86(6):770-773
T-lymphoblastic leukemia/lymphoma is an aggressive condition with frequent involvement of the mediastinum, occurring most frequently in older children, adolescents, and young adults. The involvement of extranodal sites is less common, and abdominal dissemination is unusual, but when present it primarily involves the liver and spleen. However, primary lymphoma of the adrenal glands is rare. The majority of reported cases presented with a B-cell immunophenotype. Herein, we report the case of a patient with T-lymphoblastic leukemia/lymphoma who presented predominantly with bilateral adrenal masses without lymphadenopathy, and whose clinical course deteriorated rapidly.
Adolescent
;
Adrenal Glands
;
B-Lymphocytes
;
Child
;
Humans
;
Liver
;
Lymphatic Diseases
;
Lymphoma
;
Mediastinum
;
Spleen
;
T-Lymphocytes
;
Young Adult
5.Fatal Invasive Pulmonary Aspergillosis after Combined Induction with Rituximab and Antithymocyte Globulin for Kidney Transplantation in a Sensitized Recipient, and Early Rejection Therapy with Plasmapheresis and Low-dose Immunoglobulin.
Da Wun JEONG ; Sang Ho LEE ; Ju Young MOON ; Yang Gyun KIM ; Yu Ho LEE ; Kipyo KIM ; Hochul PARK ; Sun Hyung JOO
The Journal of the Korean Society for Transplantation 2017;31(1):52-57
A high degree of sensitization to human leukocyte antigen requires more intensive induction therapy; however, this increases vulnerability to opportunistic infections following kidney transplantation. Although recent studies have suggested that combined induction therapy with antithymocyte globulin and rituximab would be more effective in highly sensitized kidney recipients, we experienced a case of near-fatal invasive pulmonary aspergillosis 2 months after combined induction and early rejection therapy for graft dysfunction. Fortunately, the patient recovered with intensive antifungal treatment and lung lobectomy for a necrotic cavity. Antifungal prophylaxis should be considered in cases undergoing intensive induction therapy.
Antilymphocyte Serum*
;
Humans
;
Immunoglobulins*
;
Invasive Pulmonary Aspergillosis*
;
Kidney Transplantation*
;
Kidney*
;
Leukocytes
;
Lung
;
Opportunistic Infections
;
Plasmapheresis*
;
Rituximab*
;
Transplants
6.Report of Nation-wide Questionnaire Survey for Abdominal Aortic Aneurysm Treatment in Korea.
Young Wook KIM ; Seung Kee MIN ; Yong Bok KOH ; Seung Nam KIM ; Jang Sang PARK ; In Sung MOON ; Sang Woo PARK ; Seung HUH ; Jun Young CHOI ; Hochul PARK ; Won Hyun CHO ; Hyoung Tae KIM ; Ki Hyuk PARK ; Jung Ahn RHEE ; Kwang Jo CHO ; Sung Woon CHUNG ; Yong Shin KIM ; Dong Ik KIM ; Young Soo DO ; Sang Joon KIM ; Jongwon HA ; Jae Hyung PARK ; Hyuk AHN ; Taeseung LEE ; Joong Haeng CHOH ; Doosang KIM ; Won Heum SHIM ; Do Yun LEE ; Koing Bo KWUN ; Bo Yang SUH ; Woo Hyung KWUN ; Yong Pil CHO ; Geun Eun KIM ; Tae Won KWON ; Hong Rae CHO ; Byung Jun SO ; Hee Jae JUN ; Shin Kon KIM ; Sang Young CHUNG ; Soo Jin Na CHOI ; Sung Hwan KIM ; Jeong Hwan CHANG ; Lee Chan JANG ; In Gyu KIM ; Hyun Chul KIM
Journal of the Korean Society for Vascular Surgery 2005;21(1):10-15
While endovascular aneurysm repair (EVAR) is prevailing for the treatment of abdominal aortic aneurysm (AAA) in modern vascular practice, PURPOSE: we conducted nationwide questionnaire survey to investigate the current status of AAA treatment and their results in Korea. METHOD: We reviewed the replies from 28 hospitals (33 departments) to the questionnaire inquiring annual number, clinical features, mode of treatment and results of AAA patients during the period from Jan. 2000 to Jul. 2004. Results: 980 AAA patients were reported including 292 ruptured AAA (29.8%) and 688 non-ruptured AAA (70.2%). For treatment of AAA, 834 (85.1%) surgical repairs (SRs) and 111 (11.3%) endovascualr aneurysm repairs (EVARs) were performed while 35 patients (3.6%) died of AAA rupture before operation. The locations of AAA were infrarenal in 889 (90.7%), juxtarenal in 62 (6.3%), and suprarenal in 29 patients (3.0%). Among 834 patients undergoing SR, 577 patients (69.2%) had non-ruptured AAAs and 257 patients (30.8%) had ruptured AAAs. Mean operative mortality rate was 4.1% after elective SRs, 30.7% after SR for ruptured AAAs, and 2.3% after EVARs. The reported brand name of stent graft devices were various including domestic custom-made in 56 (50.5%), imported brand in 18 (16.2%) while 37 (33.3%) stent grafts were not reported their brand name. The frequencies of type I and III endoleaks after EVAR were reported 5.8% and 5.8% respectively in 86 patients with an available data. CONCLUSION: SR has been used as a major treatment option in Korea for the treatment of AAA patients while EVAR is increasing. The mortality rate of SR of AAA was comparable to western multi-center trial reports but mortality or morbidity rates of EVAR were unable to know in this questionnaire survey.
Aneurysm
;
Aortic Aneurysm
;
Aortic Aneurysm, Abdominal*
;
Blood Vessel Prosthesis
;
Endoleak
;
Humans
;
Korea*
;
Mortality
;
Questionnaires*
;
Rupture
;
Treatment Outcome