Background: The inclinations and movements of teeth after premature loss of second primary molar cause narrowing in the space of second permanent premolar. Objectives: (1) To evaluate the degree of space loss after premature loss of second primary molar due to teeth inclinations and movements. (2) To assess the effectiveness of the fixed space maintainer and fixed space regained. Subjects and method: This was a prospective trial study. Records of patients were analyzed to evaluate degree of the space loss due to teeth inclinations and movements, fixed space maintainer was used for cases have adequate space and fixed space regain for cases do not have. Results:Loss of space was 6.42% \xb1 0.62 mm and 3.78 \xb1 0.71 mm when second primary molar was extracted before and after first permanent molar erupt, respectively. In maintaining space, 92.9% of excellent results, 7.1% of good and 0% of failure. In regaining space, 88% of excellent results, 8% of good and 4% of failure. Conclusion: After premature loss of second primary molar, adjacent teeth incline and move resulting in loss of space, the degree of space loss depended on timing of tooth extraction. The study shows the effectiveness of fixed space maintainer and fixed space regain in maintaining and regaining spaces.
Molar ;

Backgrounds: cholecystitis is a common disease in surgery. The rate of acute cholecystitis alone without gall stones in the literature is approximately 50-10% of all acute cholecystitis. In Vietnam, this prevalence is very high, up to 47% of acute cholecystitis alone and the disease is common in people over age 50, with a history of hypertension. Objectives: to descript clinical, paraclinical features, and results of acute cholecystitis surgical treatment (open surgery and laparoscopic surgery) in the elderly at Viet Duc Hospital. Subjectives and Method: a cross-sectional study was carried out on 119 patients aged 60 or older diagnosed with acute cholecystitis, was operated at the Viet Duc hospital from January 2006 to July 2006. Status of body organs was assessed by classification of the American Society of Anesthesiologists (ASA). Results: cholecystitis in the elderly was mainly caused by chronic inflammation due to stone (88.2%). The rate of acute inflammation accounts for 11.8%. Female (63.9%). The most commonly age group was from 60-69 years old. Scheduled surgery accounts for 75.6%, emergency surgery 24.4%. Open surgery accounted for 11.8%, laparoscopic surgery accounted for 84%. Earlier results: good 87.4%, average 8.4%, poor 4.2%. Results after 3 months: good result accounted for 88.7%. Conclussion: cholecystitis in the elderly was mainly caused by chronic inflammation due to stone. Surgical treatment was generally good results (including early and late results).
Cholecystitis/ pathology ; surgery ;

Background: Hypertension is an important risk factor that increases the cardiovascular disease-related morbidity and mortality, especially in elderly people. Objectives: The study aims to identify the hypertension rate among elderly residents of Can Tho city and some demographic, economic and social factors that were associated with hypertension in view of hypertension is changing with social and economic development. Subjects and method: The cross-sectional study involved 594 elderly people who were living in Can Tho city. Blood pressure was measured by the Korrotkoff method. The demographic, economic and social information was collected using questionnaire-based direct interviews. Results: The hypertension rate was quite high in the elderly group (51.9%). According to the WHO\u2019s ISH criteria, stage III occupied nearly 10%, stage II was approximately 15% and nearly one third of them in stage I. Age and living location were found to have significant impact to blood pressure status. Compared to the age group of 60 to 69, the elderly people in the age group of 70 to 79 were more likely to have hypertension by one and half times. And the risk was more than twice as high in the age group of 80 and above. These relationships were significant to p<0.05. The elderly people who were living in rural areas had twice the chance of having hypertension than those living in urban areas (p<0.001). Conclusion: The hypertension rate was quite high in elderly people in Can Tho city, Viet Nam. Age and living place were factors related to hypertension status in the elderly.
Hypertension ; Elderly

Background: Many research works showed that menstruation is caused by the sudden reduction of the estrogens and progesterone to low levels of secretion at the end of the menstrual cycle. However, it should be investigated to which levels the concentration of these two hormones sharply reduces to cause menstruation. Objective: To determine estradiol concentration at the beginning of menstruation, the second day of menstruation and the ending of menstruation during the menstrual cycle. Subject and methods: 30 women with the normal menstrual cycle and 30 women with the long menstrual cycle were used as subjects to determine estradiol concentration at the day at the beginning of menstruation, the second day of menstruation and the last day of menstruation during the menstrual cycle. Result and Conclusion: In the women group with the normal menstrual cycle, the estradiol concentration: at the day at the beginning of menstruation is 159.93 \xb1 51.29 pmol/L, at the second day of menstruation is 170.58 \xb1 46.54 pmol/L and at the lastday of menstruation is 177.55 \xb1 46.42 pmol/L. In women in the group with long menstrual cycle, the estradiol concentration: at the day of beginning of menstruation is 154.55 \xb1 61.60 pmol/L and at the last day of menstruation is 154.55 \xb1 61.60 pmol/L.
menstrual cycle ; estrogen ; estradiol

Background: In the procedure of tendon transfer to treat low radial nerve palsy, recovering movement amplitude for toes is not difficult. It is more important to select the appropriate motive muscle. Previously, pillar muscle was commonly used as motivation for stretching fingers, but many authors opposed this because it\u2019s affecting the function of the hand. Objectives: To evaluate the clinical features of low radial nerve palsy and the outcomes of the treatment of non-recoverable low radial nerve palsy by Smith's procedure of tendon transfer. Subjects and methods: 36 patients suffering from irreversible low radial nerve palsy were treated by Smith's procedure of tendon transfer from Jan 2000 to Jan 2008. Mean follow-up was 23 months. Outcomes assessment was based on Tajima's criteria. Results: All 30 patients were satisfied with the operation and were greatly improved both their functional and aesthetic aspects. In term of biomechanics, the Flexor Carpi Radialis (FCR) is more suitable for reconstruction of the Extensor Digitorum Communis (EDC) in comparison with the flexor carpi ulnaris (FeU) or the power density spectrum. The patients showed good movements of the wrist and fingers/ the thumb moved independently with satisfactory extension and abduction/ the grip strength was rapidly improving. Conclusions: The use of the FCR for reconstruction of the EDC is a suitable choice and Smith's procedure of tendon transfer is a good procedure for the treatment of irreversible radial nerve palsy.
procedure of tendon transfer ; Non-recoverable low radial nerve palsy

SARS-CoV-2 variant B.1.1.7, first detected in September 2020 in the United Kingdom of Great Britain and Northern Ireland, has spread quickly to many countries around the world. While some publications have described the clinical features of adult patients with the B.1.1.7 variant, little information is available on newborn patients. We report the clinical characteristics, treatment and care practices for a 21-day-old newborn patient who was confirmed to be infected with SARS-CoV-2 variant B.1.1.7 in Viet Nam during contact tracing after her father was confirmed to be infected with SARS-CoV-2. The patient displayed no symptoms of COVID-19 on admission but 3 days later developed diarrhoea, vomiting, a runny nose and a productive cough. These symptoms lasted for 3 days before becoming milder for 1 day and then stopping until discharge. During treatment, the patient received Vietnamese traditional herbal peppermint extracts for cough and digestive probiotics for diarrhoeal symptoms. A saltwater solution (Sterimar 0.9%) was used to clean the patient’s sinuses. The patient was cared for and fed breastmilk by her mother, who was provided with personal protective equipment, including sterilized infant equipment, medical masks and hand sanitizer, during hospitalization. The patient’s mother tested negative for SARS-CoV-2 throughout hospitalization. In conclusion, we found no severely abnormal clinical symptoms in a newborn infected with SARS-CoV-2 variant B.1.1.7 during treatment. Our case suggests that newborn patients with the B.1.1.7 variant can receive exclusive breastmilk feeding if sufficient preventive measures are provided for both mother and child.

Background: Laparoscopic cholecystectomy is the first laparoscopic surgery that was performed at Cho Ray hospital in September 1992. In 2005, Quang Tri general hospital has performed successfully the first case of laparoscopic appendectomy. Objectives: To access the preliminary results of application on endoscopic surgery in Quang Tri general hospital. Subjects and method: A prospective study was conducted on 140 patients with laparoscopic surgery or retroperitoneal surgery, was performed in Quang Tri general hospital from September, 2005 to April, 2006. Results:Among 140 patients was operated, there was only one case of postoperative intestinal obstructive complication (accounted for 0.7%), no case of death. Operative aged was between 11 and 70 years old. The average surgical time was 65 minutes for cholecystectomy, 35 minutes for appendectomy, 85 minutes for ureterolithotomy, 80 minutes for gynecological diseases. 2 cases of cholecystectomy and appendectomy changed open surgery. Conclusion: Laparoscopic surgery is a safe and effective method. It can be developed in provincial hospitals. Quang Tri general hospital has successful preliminary developed the new technique.
Laparoscopy ;

Background: In Vietnam, the HIV/AIDS pandemic is quickly spreading, almost totally in young people and among injecting drug users.The transition phase from smoking to injecting is very important for the life of injecting drug users because it is a risk factor of disease transmission. Objectives: (1) To analyze the transition phase from smoking/sniffing to injecting of the young male heroin users in Ha Noi. (2) To describe some factors related to the transition phase in these people. Subjects and method: A cross-sectional study carried out from September 2004 to September 2005 at 9 districts in Ha Noi city. The subjects were 1115 young men aged 16 to 29 years, who has been living in Ha Noi for over 6 months and smoked/sniffed heroin within the last 30 days. Results and conclusions: The average time of drug user in the 1115 subjects was 4.7 years. The majority started using drug at the age of 18.4 +/- 3.1 years. In which, 71 % consume the drugs by injection. The average time from smoking to injecting is 2.49 +/- 2.2 years. The main reasons for injecting drugs were for being faster \u2018on the height\u2019 (42%) and cheaper (40%). Some factors related to the transition phase included: age of the first heroin use, year of the first heroin use, situation for migrating into Ha Noi, knowledge level, the kind of drug used for the first time. Young people began using heroin in the year 2000 had a quicker transition phase than those using heroin before 1997 (p< 0.01).
injecting drug user ; drug user ; heroin

Background: Fragile X Syndrome (FXS) is the second cause of Mental Retardation (MR) and the first cause of familiar MR. This syndrome affects up to 1/4000 men and 1/8000 women. X syndrome is often diagnosed by molecular biology technique such as RCR and Southern blot. Until now there is no study on FXS in Vietnam. Objectives: This study is aimed at: (1) Determine FXS among children with MR by technique of molecular biology. (2) Determine the mutation of FMR1 gen in families having children with FXS. Subject and Method: 214 children between 6 and 16 years of age (136 male and 78 female) with MR were analyzed FMR1 gen by PCR and Southern blot techniques. Families of children with FXS were also analyzed. Result and conclusion: This is the first study on FXS using the techniques of molecular biology in Vietnam. Identified 3 children with FXS, accounting for 1.4% of MR. Children with FXS and members with full mutation and premutation were found.
Fragile X syndrome ; FMR1 gene ; Mental retardation

Background: Recently Japanese Encephalitis (JE) virus type 1 has surfaced and is co-circulated with JE virus type 3 in the northern areas of Viet Nam, so a sensitivity of JE viral antigen genotype 3 to detect IgM is required. Objectives: To compare the sensitivity of JE viral antigen genotype 1 and 3 to detect IgM against the JE virus. Materials and method: 783 cerebrospinal fluid and serum samples from viral encephalitis cases from 1999-2005 were collected and examined by MAC-ELISA for JE viral antigen genotype 1 and 3. Results: The agreement on the diagnosis of these kinds of antigen was 99.7% and the sensitivity of JE viral antigen genotype 3 was higher than that of genotype 1. Thus, JE viral antigen genotype 3 could be considered as the selected antigen for JE diagnosis in Viet Nam. IgM titer determined by JE viral antigen genotype 1 was higher than that of genotype 3 in 2003 and 2005 and lower in 1999, 2000, 2001, 2002 and 2004. Conclusion: The dominant phenomenon of JE viral genotypes differing over the years might be due to the interaction of the virus and its vectors. Further study is required to clarify this observation.
Japanese Encephalitis ; antigen