1.Epidemiological survey of lymphatic filariasis in two provinces of Gia Lai and Kon Tum
Journal of Malaria and parasite diseases Control 2004;0(3):84-91
An epidemiological survey for lymphatic filariasis was conducted in Nov.2001 in 4 communes of GiaLai and KonTum provinces. Blood was taken at night for detecting filarium,and mosquitoes were caugh for surveying entomologically.No microfilarium was detected in blood but a high rate of Culex quinquefasciatus,Culex vishnui, Culex puscocephalia was found. Dissection performed on 681 invidual mosquitoes did not show micofilarium
Elephantiasis, Filarial
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epidemiology
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diagnosis
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blood
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mosquitoes
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2.Research on the characteristics of young male heroin users at the age of 16-29 in Ha Noi
Hao Thi Minh Bui ; Vinh Quang Hoang ; Phong Quy Nguyen ; Son Minh Nguyen ; Giang Minh Le ; Tuan Minh Vu
Journal of Medical Research 2008;54(2):97-102
Background: According to statistical data of the Vietnam Ministry of Health, there were 124,223 people with positive HIV, 23,661 AIDS patients and 13,649 AIDS- related deaths up to April 30th 2007. The major transmission route is injection. Objectives: (1) To compare the characteristics of drug use in users with different time. (2) To describe the health issues and health service access of young male drug users. Subjects and method: A cross-sectional survey was carried out using a combination of medical anthropology and epidemiology methods. 1.115 young male drug users in Ha Noi between September 2004 and September 2005 were divided into 4 groups of the equivalence number, but with different drug using history. Results and conclusion: The newer drug users (within 2 years) started using drug later than the older ones, more of them started using by injecting; they transfer from smoking/sniffing to injecting as well as trying and using more different types of drugs together in shorter time than others. The proportion of HIV (+) infection in these people was higher, which states the necessity of intervention to help them enhance their knowledge to prevent HIV infection amongst themselves. Mental health care is also needed for drug users, the demand for mental health care increases with the time of drug usage.
young male heroin users
3.The potential efficacy of the E2-subunit vaccine to protect pigs against different genotypes of classical swine fever virus circulating in Vietnam
Ha Thi Thanh TRAN ; Duc Anh TRUONG ; Viet Duc LY ; Hao Thi VU ; Tuan Van HOANG ; Chinh Thi NGUYEN ; Nhu Thi CHU ; Vinh The NGUYEN ; Duyen Thuy NGUYEN ; Kohtaroh MIYAZAWA ; Takehiro KOKUHO ; Hoang Vu DANG
Clinical and Experimental Vaccine Research 2020;9(1):26-39
4.HPAI-resistant Ri chickens exhibit elevated antiviral immune-related gene expression
Thi Hao VU ; Jubi HEO ; Yeojin HONG ; Suyeon KANG ; Ha Thi THANH TRAN ; Hoang Vu DANG ; Anh Duc TRUONG ; Yeong Ho HONG
Journal of Veterinary Science 2023;24(1):e13-
Background:
Highly pathogenic avian influenza viruses (HPAIVs) is an extremely contagious and high mortality rates in chickens resulting in substantial economic impact on the poultry sector. Therefore, it is necessary to elucidate the pathogenic mechanism of HPAIV for infection control.
Objective:
Gene set enrichment analysis (GSEA) can effectively avoid the limitations of subjective screening for differential gene expression. Therefore, we performed GSEA to compare HPAI-infected resistant and susceptible Ri chicken lines.
Methods:
The Ri chickens Mx(A)/BF2(B21) were chosen as resistant, and the chickens Mx(G)/ BF2(B13) were selected as susceptible by genotyping the Mx and BF2 genes. The tracheal tissues of HPAIV H5N1 infected chickens were collected for RNA sequencing followed by GSEA analysis to define gene subsets to elucidate the sequencing results.
Results:
We identified four differentially expressed pathways, which were immune-related pathways with a total of 78 genes. The expression levels of cytokines (IL-1β, IL-6, IL-12), chemokines (CCL4 and CCL5), type interferons and their receptors (IFN-β, IFNAR1, IFNAR2, and IFNGR1), Jak-STAT signaling pathway genes (STAT1, STAT2, and JAK1), MHC class I and II and their co-stimulatory molecules (CD80, CD86, CD40, DMB2, BLB2, and B2M), and interferon stimulated genes (EIF2AK2 and EIF2AK1) in resistant chickens were higher than those in susceptible chickens.
Conclusions
Resistant Ri chickens exhibit a stronger antiviral response to HPAIV H5N1 compared with susceptible chickens. Our findings provide insights into the immune responses of genetically disparate chickens against HPAIV.