to assess the effects and side-effects of iodized oil (IO) through the changes of thyroid functions. Subject were randomly selected from goiter people living in Thoi An commune, O Mon district, Can Tho province, they were treated with single dose 400mg of IO. Method: randomized controlled trial. Conclusion: IO is effective in repairing iodine deficiency through the improvements of hormone level: serum TSH level decreased, but serum T3 and T4 level were changed insignificantly. Effects of single dose 400mg of IO lasted about 12 months. There was no one experienced clinical thyrotoxicosis, 14.3% developed sub-clinical thyrotoxicosis after 12 months in group of older subjects and experienced chronic goiter
goiter ; Thyroid Gland ; Iodized Oil ; prevention & control