252 pathogenic bacterial strains have been isolated in Friendship hospital in 1997. Almost strains (66%) are gram negative. The majority of bacteria that caused urinary tract infection are gram negative rods. Gram positive cocci are predominant in the strains isolated from pus, exudates. All strains are tested for antibiotic sensitivity. Enterobacteriaceae are still sensitive to the third generation of cephalosporin, morfloxacin, gentamyxin, netilmixin. Pseudomonas aeruginosa are only sensitive to Amikaxin. Staphylococcus aureus are resistant to oxacillin in high level (54.6%), but still susceptible to bactrim, gentamyxin, vancomyxin.
Bacterial Infections ; drug resistance

The oral Bio-availability of two different capsule formulations of artmisinin was carried out in six rabbits divided in two groups and seven healthy male volunteers in a single-dose crossover design with randomization for dosing sequence. The experimental results showed that the relative bioavailability of the formulation, that was made of artemisinin solid dispersion system using Eudragit L100 as a carrier on ratio 1:1, was more two times higher than the modification of artemisinin capsules without any modifications. There was a good correlation between in vitro dissolution data obtained by dissolution test with the mean AUG values of each studied group after oral administration.
Artemisinine ; Pharmaceutical Preparations ; therapeutics

In this study, the extracts of four traditional herbs of ViÖt Nam (Hydrangea macrophylla, Eucommia ulmoides Olive, Scrophularia burianna Mig, Morinda ciuifolia L.) have been assessed for the hypoglycemic effect on normal mice. These extracts were administered by intraperitoneal or oral routes with dose of 200 - 300mg/kg, and 1000 - 1500mg/kg respectively. No evident hypoglycemic effect was showed with all extracts of these herbs
Hypoglycemic Agents ; Medicine ; Medicine, Traditional ; Mass Screening

The ethanol extract of Anemarrhena aspheloides Bunge-Liliaceae in concentration of 2, 4 and 8mg/ml increases the insulin secretion of isolated islets of normal Wistar rat and also of genetic diabetes GK incubated in glucose 3.3 or 16.7mM. So, in addition of Mangiferin, one Anemarrhena active substance having the hypoglycemic effect due to increasing the insulin sensitivity of peripheral tissues, there are the other substances directly stimulating the pancreas islets to secrete insulin
Insulin ; Animal Experimentation ; Islets of Langerhans

Wedelia chinensis (Osbeck) Merr. (Synomyme: W. calendulacea Less.) was commonly used in folk medicine for the treatment of furunculosis, phlegmon, impetigo, cystitis. Two other plants, namely Tridex procumbens L. and Phyla nodiflora (L.) greene were often confused with W. chinensis. The study presented detailed descriptions of the morphological, anatomical and palynological characters of the three species, offering an easy distinguishment of the plants
Medicine, Traditional ; Plants ; Botany

Wedelia calen-dulacea Less. (Asteraceae) is well known for its antibacterial, demulcent and antifebrile properties, it is a traditional medicine which wild growing in many areas in Viet Nam. The researchers firstly study its chemical composition. Results of the chemical analysis show that: The plant contains flavonoid, alcaloids, coumarin, triterpenoid saponins, tanin, sugars, fat, sterols and carotenoid. The content of total flavonoids is about 1% (on dry basis), at least 11 spots on chromatogram. The content of total saponins is about 12% (on dry basis). The analysis with 3 different solvent systems revealed at least 15 spots on chromatogram. Some of the spots can be shown with both flavonoid and coumarin reagents, these are tentatively called coumestan components.
Asteraceae ; Medicine, Traditional ; Biochemistry

The 1:1 fluid extract of Wedelia calendulacea Less. aerial part was used for the evaluation of the plant hepatoprotective effect. The results of the pharmacological studies included: (1) Oxidative activity: 83.1% (in vitro), (2) Decrease of malonyl dialdehyde in mouse liver: 25.1%, (3) Decrease of the serum glutamate pyruvic transaminase level: 34.1%, (4) Decrease of the concentration of bilirubin in mouse serum: 10.4%, (5) Increase of the bile flow in mice: 88.8%. Conclusion: W. calendulacea had a good hepatoprotective effect in mouse model.
Medicine, Traditional ; Therapeutics ; Gastroenterology ; drugs

The Wedelia calendulacea Less. in Van Dien area, Ha Noi, rats of the body weight of 20-22g were divided into 3 groups. In order to use Wedelia calendulacea Less. in treating liver diseases, fractions from the plant have been studied pharmacologically. This paper presents the method of extraction of oleanolic acid and results of its anti-oxidative effect. The studies have revealed that amount of liver MDA of the treated mice decreased by 44.8%, and that of serum GPT decreased by 26.3%. These results show that oleanolic acid do take part in the hepatoprotective activity of the plant
Plants ; Plants, Medicinal ; Liver Diseases ; liver ; drugs ; Oleanolic Acid

Aedes aegypti mosquitoes had been collected at field of some Northern provinces between 2001 and 2004 for studies of their susceptibility to insecticides. It was seen that: all of tested mosquitoes dropped immediately 100% and 100% killed after 24 hours. The results showed that all tested mosquitoes were highly susceptible to insecticides, such as permethrin, lambda cyhalothrin, and malathion from 2001-2004 in Northern region. The provinces participate in the test was up fro 5-7. Using the insecticides to kill Aedes aegypti by ULV spraying was effective in Northern provinces in Vietnam. It is adviced to send mosquitoes and lavae in June and July when the density of mosquitoes and lavae is high. Therefore, expanding studies to other provinces throughout the country to identify susceptibility of Aedes aegypti to insecticides is very necessary for Dengue Hemorrhagic Fever vector control.
Culicidae ; Insecticides

A retrospective study on 283 people who are 15 years old and more with suspicious tuberculosis seen at District Tuberculosis Clinic, Thai Nguyen province on December 2000. Result: These patients’ knowledge on tuberculosis are quite enough and right: 91% know at least one symptom/sign of suspicious tuberculosis, many people know the symptom of long term cough (87%). 74.2% people know tuberculosis cause by tuberculosis bacteria, 19.1% people though that tuberculosis is caused by hard working and only 1.1% though it is caused by hereditary. Education, occupation and information source access had impacted to the knowledge on tuberculosis.
Tuberculosis ; Knowledge ; Diagnosis