Background: Gastric cancer is the second common disease among types of cancer, followed by lung cancer for male and breast cancer for female. The selection of appropriate regimens for illness and economic conditions of patients is always a difficult problem for clinicians. Objectives: To assess preliminary results of chemotherapy in treatment of gastric cancer in Hai Phong. Subjects and method: A longitudinal, cross-section study was conducted on 57 patients with gastric cancer (35 male, 21 female), treated in Viet Tiep hospital from January, 2002 to June, 2006. All of them were in stage of Dukes C, treated postoperative supported chemotherapy. Results: Side effects were common seen as vomit, nausea and diarrhea. They were often mild and disappeared after stopping medication. 30/57 patients responded to treatment. 21 patients were treated with regimen 5FU, however, amount of treatment cycles was very scattered and treatment effect was unclear. 36 patients were treated with multi-chemical regimens as FUFA, FAM and ELF. Their response to treatment was more clearly than regimen 5FU. During treatment, there were 6 patients who had not completely responded to treatment. In which, 4 patients developed more seriously: metastasis to liver, ovary, bone and lung. 2 patients had died. Conclusion: Regimen 5FU had a little toxicity. Regimen FUFA was more effective. The role of chemotherapy in supported treatment was unclear. Chemotherapy could be applied to patients with early stage of Dukes B.
Stomach Neoplasms/ therapy ; Drug Therapy ;

Anaplasma marginale and A. platys were detected and characterized (16S rDNA sequence analysis) from dairy and indigenous cattle, and the latter in domestic dogs in Vietnam. A phylogenetic tree was inferred from 26 representative strains/species of Anaplasma spp. including 10 new sequences from Vietnam. Seven of our Vietnamese sequences fell into the clade of A. marginale and 3 into A. platys, with strong nodal support of 99 and 90%, respectively. Low genetic distances (0.2–0.4%) within each species supported the identification. Anaplasma platys is able to infect humans. Our discovery of this species in cattle and domestic dogs raises considerable concern about zoonotic transmission in Vietnam. Further systematic investigations are needed to gain data for Anaplasma spp. and members of Anaplasmataceae in animal hosts, vectors and humans across Vietnam.
Anaplasma marginale ; Anaplasma ; Anaplasmataceae ; Animals ; Asian Continental Ancestry Group ; Cattle ; DNA, Ribosomal ; Dogs ; Humans ; Phylogeny ; Trees ; Vietnam

Objective: To investigate the cause of a foodborne outbreak that occurred in Dong Nai province, Viet Nam, in 2024, and implement control measures. Methods: An initial investigation was conducted to confirm the outbreak, which was followed by epidemiological and environmental investigations to find the plausible causative food item. Clinical specimens and food samples were tested to identify the pathogen. Results: A total of 547 symptomatic cases were recorded, of whom two were in severe condition requiring extracorporeal membrane oxygenation and ventilation, one of whom died. Among 99 interviewed cases, the mean incubation time was 9 hours (range 2–24 hours), with the main symptoms being fever, abdominal pain, diarrhoea and vomiting. All patients had eaten banh mi from a local bakery. Salmonella spp. were identified in food samples and clinical specimens. The bakery halted production, and the outbreak ended after 1 week. Discussion: All the patients were exposed to only one food in common, which facilitated the investigation process. This outbreak is a reminder to small retailers and take-away shops of the importance of food safety management in preventing similar future outbreaks. All food handlers must comply with food hygiene principles, especially in hot temperatures, which boosts bacterial growth.