1.Erratum: Author Correction.
So Mi CHOI ; Min Youp CHOI ; Woo Dae KANG ; Ho Sun CHOI ; Seok Mo KIM
Obstetrics & Gynecology Science 2014;57(5):424-424
The author list should be corrected.
2.A case of infectious mononucleosis.
Yong Jin AHN ; Hae Youp KIM ; Hyung Jin CHUNG ; Hyun Ho SHIN ; Dong Hee CHO
Korean Journal of Infectious Diseases 1991;23(3):189-193
No abstract available.
Infectious Mononucleosis*
3.Combined therapy of advanced paranasal sinus cancer.
Seung Ho CHO ; Min Sik KIM ; Heung Youp LEE ; Young Chul CHOI ; Byung Do SUH
Korean Journal of Otolaryngology - Head and Neck Surgery 1991;34(6):1292-1297
No abstract available.
Paranasal Sinus Neoplasms*
4.Comparison of Inhibitory Effects of 5-Fluorouracil and Mitomycin C on Proliferation of Fibroblagts and Retinal Pigment Epithelial Cells.
Se Youp LEE ; Kyung Ho WOO ; Kwang Soo KIM
Journal of the Korean Ophthalmological Society 1996;37(8):1397-1404
We evaluated the antiproliferative properties of Fluorouracil(5-FU) and Mitomycin C(MMC) in a tissue culture model of fibroblast and retinal pigment epithelial cells. Both drugs caused the dose dependent inhibition on proliferation of the cultured cells. The concentrations of 5 FU and MMC required for 50% inhibition of cellular growth(ID50) were 0.45mg/L and 2.3 X 10(-3)mg/L for rabbit subconjuntival fibroblasts, 0.21mg/L and 3.5 X 10(-3)mg/L for rabbit dermal fibroblast, 0.58mg/L and 7.4 X 10(-3)mg/L for rabbit retinal pigment epithelial cells, and 0.38mg/L and 3.4 X 10(-3)mg/L for human retinal pigment epithelial cells, respectively. In general, ID50 of both drugs were higher in retinal pigment epithelial cells than in fibroblasts but MMC showed same inhibitory effect on proliferation of all cell types at lower doses in comparision to 5-FU. These results suggest that 5-FU and MMC may be of significant values in the treatment of intraocular proliferative disorders and MMC, however, seems to be more useful than 5-FU if it's safty would be proved.
Cells, Cultured
;
Epithelial Cells*
;
Fibroblasts
;
Fluorouracil*
;
Humans
;
Mitomycin*
;
Retinaldehyde*
5.A Case of Ectopic Pregnancy within a Previous Cesarean Scar.
Sang Youp OH ; Joon Cheol PARK ; Jeong Ho RHEE ; Jong In KIM
Korean Journal of Obstetrics and Gynecology 2003;46(10):2039-2042
Implantation of a gestational sac within a previous cesarean scar is the rarest form of ectopic pregnancy. A delay in either diagnosis or treatment can lead to uterine rupture, hysterectomy, and significant maternal morbidity due to severe hemorrhage. As developing of transvaginal ultrasound and MRI, early diagnosis could be made and conservative treatment could be possible. We have recently experienced a case of intramural pregnancy implanting in the scar of cesarean section, and enabled the successful treatment to preserve the patient's reproductive capability.
Cesarean Section
;
Cicatrix*
;
Diagnosis
;
Early Diagnosis
;
Female
;
Gestational Sac
;
Hemorrhage
;
Hysterectomy
;
Magnetic Resonance Imaging
;
Pregnancy
;
Pregnancy, Ectopic*
;
Ultrasonography
;
Uterine Rupture
6.Tracheal Agenesis: A case report.
Ji Yung LEE ; Sang Youp KIM ; Kyo Young LEE ; Se Ho MOON
Korean Journal of Anesthesiology 1998;34(1):187-191
Agenesis of trachea is a rare congenital anomaly. The main signs are respiratory distress, cyanosis, inability to vocalise and impossible tracheal intubation. There is no long-term surgical solution at present, therefore the condition is ultimately fatal. We report a case of tracheal agenesis. We anesthetized a 2.25 kg neonate for endoscopic examination, who was intubated successfully. Beyond 2.5 cm from the vocal cord, there was no trachea and we can only see esophageal lumen with fistula opening. After the endoscopic examination, exploratory thoracotomy was done, but surgical correction was impossible. After the surgery, she died from progressive ventilatory failure. Autopsy revealed a Floyd's type II tracheal agenesis with tracheo-esophageal fistula.
Autopsy
;
Cyanosis
;
Fistula
;
Humans
;
Infant, Newborn
;
Intubation
;
Thoracotomy
;
Trachea
;
Vocal Cords
7.Effectiveness of an i-PTH Measurement in Predicting Post Thyroidectomy Hypocalcemia: Prospective Controlled Study.
Jin Pyeong KIM ; Jung Je PARK ; Hee Young SON ; Rock Bum KIM ; Ho Youp KIM ; Seung Hoon WOO
Yonsei Medical Journal 2013;54(3):637-642
PURPOSE: Hypocalcemia is the most common complication after total thyroidectomy. The purpose of this study was to determine whether measurement of intact parathyroid hormone (i-PTH) level in thyroidectomy patients could predict hypocalcemia. MATERIALS AND METHODS: We performed a prospective study of patients undergoing total thyroidectomy. Serum concentration of i-PTH, total calcium (Ca), ionized calcium (Ca2+), phosphate (P), magnesium (Mg), and albumin were measured preoperatively and at 0 hour, 6 hours, 12 hours, 24 hours, 48 hours, and 72 hours postoperatively. RESULTS: 108 patients were recruited to the study. A total of 50 patients (46%) experienced hypocalcemia. The serum i-PTH concentration was linearly related to the time of measurement, while concentrations of P, Mg, albumin, Ca, and Ca2+ were not. We compared odds ratios, and found that the concentration of i-PTH at 6 hours post operation was the most closely related to the occurrence of hypocalcemic symptom. On ROC analysis using i-PTH level at 6 hours, an i-PTH level of 10.6 mg/dL was found to maximize both sensitivity and specificity at the same time point. CONCLUSION: We found that i-PTH was a predictor of hypocalcemia, and that the earliest predictor of hypocalcemic symptoms was an i-PTH concentration lower than 10.6 mg/dL obtained 6 hours after total thyroidectomy.
Calcium/blood
;
Humans
;
Hypocalcemia/*diagnosis
;
Magnesium/blood
;
Odds Ratio
;
Parathyroid Hormone/*blood
;
Phosphates/blood
;
Postoperative Complications/blood/*diagnosis
;
Prospective Studies
;
Serum Albumin
;
Thyroidectomy/*adverse effects
8.Lower Lip Reconstruction Using a Submental Island Flap.
Seung Hoon WOO ; Ho Youp KIM ; Joon Sik KIM ; Jin Pyeong KIM
Korean Journal of Otolaryngology - Head and Neck Surgery 2011;54(4):293-296
Squamous cell carcinoma (SCC) of the lower lip is the most common malignant tumor, comprising 90% of all lip SCC. The typical picture of SCC of the lower lip is an ulcerated lesion with raised margins. Surgery is the treatment of choice for SCC of lower lip. After resection, reconstruction is important both aesthetically and functionally, because the lower lip is a prominent location in the face and it is where essential functions of the sphincter are carried out as in assisting mastication, swallowing, phonation, and expressing emotion. Depending on the location and size of the tumor, different types of flaps are used. We describe here a successful technique to reconstruct a large lower lip defect using a submental island flap and a mucosal flap for patients.
Carcinoma, Squamous Cell
;
Deglutition
;
Humans
;
Lip
;
Lip Neoplasms
;
Mastication
;
Phonation
;
Surgical Flaps
;
Ulcer
9.Stand-Alone Cages for Anterior Cervical Fusion: Are There No Problems?.
Sang Youp HAN ; Hyun Woo KIM ; Cheol Young LEE ; Hong Rye KIM ; Dong Ho PARK
Korean Journal of Spine 2016;13(1):13-19
OBJECTIVE: There are complications in stand-alone cage assisted anterior cervical discectomy and fusion (ACDF), such as cage subsidence and kyphosis. Here we report our clinical result on ACDF, comparing with stand-alone cages and with cervical plate system for degenerative cervical spine diseases. METHODS: Patients with degenerative cervical disease who were diagnosed and treated in Konyang University Hospital between January 2004 and December 2014 were included in this study. Patients who had operation in single level ACDF were selected. Patients scored the degree of pain using visual analog scale before and after the surgery. Subsidence was defined as ≥3-mm decrease of the segmental height, and cervical kyphosis was defined as progression of ≥5° at 12 months after postoperative follow-up compared to that measured at the immediate postoperative period. RESULTS: A total of 81 patients were enrolled for this study. Forty-five patients were included in a cervical plate group and the others were in stand-alone cage group. There was no statistical difference in pain score between the 2 groups. Segmental subsidence was observed in 7 patients (15.6%) in plate-assisted cervical fusion group, and 13 patients (36.1%) in stand-alone cage group. Segmental kyphosis was observed in 4 patients (8.9%) in plate-assisted cervical fusion group, and 10 patients (27.8%) in stand-alone cage group. There was statistical difference between the 2 groups. CONCLUSION: There was no difference in pain between 2 groups. But stand-alone case group showed higher incidence rate than plate-assisted cervical fusion group in segmental subsidence and cervical kyphosis. When designing cervical fusion, more attention should be given selecting the surgical technique.
Diskectomy
;
Follow-Up Studies
;
Humans
;
Incidence
;
Kyphosis
;
Postoperative Period
;
Spine
;
Visual Analog Scale
10.Comparison of Nutritional Status According to Serum C-reactive Protein Concentration in Hemodialysis Patients.
Joon Young KIM ; Kun Ho KWON ; Hong Youp CHOI ; Kyoung Soo KIM ; Yuun Kyoung YANG
Korean Journal of Nephrology 2000;19(3):461-467
Serum C-reactive protein(sCRP) is an acute-phase reactant that exhibiting negative correlation with serum albumin concentration. It was reported that sCRP is an independent predictor of survival in both hemodialysis and peritoneal dialysis patients, and an acute phase inflammation could be preceded by protein catabolism, hypoalbuminemia, anorexia and even atherosclerotic cardiovascular disease. We have evaluated serum biochemical parameters including albumin and prealbumin, Kt/Vurea, nPCR, SGA score, anthropometric parameters and diet history in 30 ESRD patients maintained on chronic hemodialysis subdivided by sCRP concentration. Upon comparing the two subgroups[high CRP group(sCRP >or= 0.4mg/dL), n=15 vs. normal CRP group (sCRP<0.4mg/dL), n=15], high CRP group showed significantly lower levels of hemoglobin(9.3+/- 0.7 vs. 9.8+/-0.6g/L, p<0.05), hematocrit(28.3+/-2.3 vs 29.8+/-1.696, p<0.05), creatinine(9.6+/-3.1 vs. 12.2+/-2.5mg/dL, p<0.05), prealbumin(20.9+/-5.0 vs. 25.8+/-6.4mg/dL, p< 0.05), SGA score(5.0+/-1.2 vs. 5.9+/-0.7, p<0.05), and percent of patients who have higher nPCR than protein intake(85.7 vs. 28.6%, p<0.05). Ferritin was significantly higher in high CRP group(503.1+/-205.7 vs. 323.3+/-186.6, p<0.05). There were no differences in age, sex, duration of hemodialysis, prevalence of diabetic nephropathy and cardiovascular disease, Kt/Vurea, nPCR, residual renal function, amount of protein intake and other nutritional parameters. In conclusion, there was higher probability of malnutrition, anemia and protein catabolism in hemo-dialysis patients with elevated sCRP concentration.
Anemia
;
Anorexia
;
C-Reactive Protein*
;
Cardiovascular Diseases
;
Diabetic Nephropathies
;
Diet
;
Ferritins
;
Humans
;
Hypoalbuminemia
;
Inflammation
;
Kidney Failure, Chronic
;
Malnutrition
;
Metabolism
;
Nutritional Status*
;
Peritoneal Dialysis
;
Prealbumin
;
Prevalence
;
Renal Dialysis*
;
Serum Albumin