Here, we report 3 cases of mixed tumor of the lacrimal gland. The age of the patients were 43, 26 and 35 respectively. The two of these were male and one female. The most outstanding complaint was exopthalmos. A mass was palpated on the orbit and eye ball deviation in downward position was present in all cases. Pathologic findings were mixed tumor of the lacrimal gland with no evidence of malignancy. These tumors were well encapsulated and any evidence of involving bone and soft tissue was not found. Modified Kroenlein-Berke operation was performed and tumor mass was removed entirely with finger dissection in all cases. The vision was not improved but the cosmetic result was satisfactorr.
Female ; Fingers ; Humans ; Lacrimal Apparatus* ; Male ; Orbit

The following case report concerns a rare bone metastasis of malignant melanoma occurring in the 4th and 5th lumbar spines and adjacent iliac crests and sacrum. A 42-year-old woman was admitted with a 6 months history of severe lumbago ar right flank pain radiating to right lower extremity. Preoperative X-ray studies revealed stag horn stone in the right renal pelvis as spondylolisthesis of the 5th lumbar spine with bilateral isthmic defects. On physical examinations, dark brown colored nevus was noted at lower lumbar regio which was removed and subjected for biopsy. Surgical exploration demonstrated a melanoma metastasis to have invaded the spine process, lamina and transverse processes of the 5th lumbar spine, adjacent L4 and sacru and iliac crests. Surrounding soft tissues, however, were apparently normal. Postoperatively course of the patient seemed to follow a rapidly terminal clinical cours.
Adult ; Animals ; Biopsy ; Female ; Flank Pain ; Horns ; Humans ; Kidney Pelvis ; Low Back Pain ; Lower Extremity ; Melanoma ; Neoplasm Metastasis ; Nevus ; Physical Examination ; Sacrum ; Spine ; Spondylolisthesis

Generalized lipodyst,rophy is characterized by generalized loss of body fat, and is asociated vith metabolic ahnormalities, including insulin resistance, hyperglycemia., and hypertriglyceridemia. like acanthosis nigricans, generalized lipodystrophy is a cutaneous marker of insulin re.istant diabetes. We report. herein a twenty year old female witti both classic generalized lipodystripin and acanthosis nigricans, in association with insulin resistant diabetes.
Acanthosis Nigricans ; Adipose Tissue ; Female ; Humans ; Hyperglycemia ; Hypertriglyceridemia ; Insulin ; Insulin Resistance ; Lipodystrophy, Congenital Generalized*

There were many instances in which glaucoma, esp. primary, combined with hearing disturbance. The etiology of these cases has not been known until now. We had 15 primary glaucoma patients for whom pure tone audiometry wa~ performed, and could find the hearing defect in high tone in 5 cases (1/3 among those patients). The audiometric curve was similar to that in the presbycusis, but severer in degree than that occured within the normal physiological aging process. The average age was 62.4 year in the group with the hearing defect, and 45.6 year in the group without the hearing defect. There were no relationship between the hearing defect and intraocular tension, visual field change, glaucomatous cupping, and duration of glaucoma. These results may support the opinion of the authors that the hearing disturbance in glaucomatous patients is related to the arterioscIerotic changes which aggrevate the presbycusis, and not related to glaucoma itself. On the otherhand, however, it is stilI impossible for us to rule out that the pleiotropic and multifactorial genetic factors may play as a common important role in the hearing disturbances and glaucoma. And further studies would be necessary for these problems.
Aging ; Audiometry ; Glaucoma* ; Hearing* ; Humans ; Presbycusis ; Visual Fields

BACKGROUND: Passive smoking is an important worldwide public health issue. In many Korean studies, parental smoking has been reported to be associated with reduced pulmonary function in children. But few studies have evaluated the effects of passive smoking on pulmonary function in adults. Therefore, we looked into this association in the study. METHODS: Participants in the study included non-smoking, healthy men (n=46) and women (n=326) from rural Korea enrolled from June to December 2006. Exposure to passive smoking was assessed by a self-administered questionnaire, and standardized pulmonary function tests were performed. RESULTS: There were significant reductions in forced expiratory volume in 1 second (FEV1, % of predicted) and forced mean expiratory flow rate 25-75% (%) among the men exposed to passive smoke compared with those not exposed (55.7 vs 75.8, P=0.010; 33.9 vs 58.6, P=0.029, respectively). There were significant reductions in FEV1 among men exposed at both workplace and home compared with men exposed only at either workplace or home (42.8 vs 49.3, 64.6; P=0.034). No significant difference in pulmonary function was found between women exposed to passive smoke compared those not exposed. There were, however, reductions in FEV1 and FEV1/forced vital capacity among the women exposed at workplace. Regression analysis showed that passive smoking negatively affected lung function, which were not statistically significant. CONCLUSIONS: Exposure to environmental tobacco smoke, particularly at the workplace, adversely affects pulmonary function in adults.
Adult ; Child ; Female ; Forced Expiratory Volume ; Humans ; Korea ; Lung ; Male ; Parents ; Public Health ; Respiratory Function Tests ; Smoke ; Smoking ; Tobacco ; Tobacco Smoke Pollution ; Vital Capacity ; Surveys and Questionnaires

Sweet's syndrome is an important cutaneous sign of underlying myeloproliferative disorder. The majority of cases have occurred with acute leukemia, primarily of the myelogenous type. We described a case of Sweet's syndrome in a patient with myelodysplastic syndrome that preceded acute myelogenous leukemia by 9 months.
Humans ; Leukemia ; Leukemia, Myeloid, Acute* ; Myelodysplastic Syndromes* ; Myeloproliferative Disorders ; Sweet Syndrome*

This analysis describes the influence of miotics (pilocarpine) on the visual field obtained from the Goldmann perimetry testing of 10 ocular hypertensive eyes (7 patients) and 10 glaucomatous eyes (8 patients) by comparison of two visual fields testing at miotic state and at normal pupil size. The analysis of visual field was done by Esterman grid for functional estimation and by section paper for gross evaluation. The results were as follows; 1. Decreased pupillary size caused not only the decrease of the gross visual field but also the decrease of the functional visual field. 2. Absolute scotoma was not influenced by the pupillary size.
Glaucoma* ; Miotics* ; Pupil ; Scotoma ; Visual Field Tests ; Visual Fields*

In order to assess a possible damage to the corneal endothelium by the increased intraocular pressure, we investigated the 8 eyes of angle closure glaucoma, 10 eyes of ocular hypertension, 20 eyes of primary open angle glaucoma, and 15 normal eyes as a control group. We photographed the central corneal endothelium with a non contact specular microscope and measured the central corneal thickness three times with a Haag-Streit pachymeter. As compared to the normal eyes the glaucomatous eyes and ocular hypertensive eyes showed a statistically significant decrease of central corneal endothelial cell density(p<0.005), but in central corneal thickness there was no statistically significant difference between two. There was a reverse correlation between the intraocular pressure and the central corneal endothelial cell density(p<0.05), but no correlations were seen between the intraocular pressure and the central corneal thickness and between the central corneal endothelial cell density and the central corneal thickness(p>0.1).
Endothelial Cells* ; Endothelium, Corneal ; Glaucoma* ; Glaucoma, Angle-Closure ; Glaucoma, Open-Angle ; Intraocular Pressure ; Ocular Hypertension*

A case of Mooren's ulcer in a 68 years old korean female has been reported. This is a rare disease and hitherto it is not reported in Korea. A brief review of litera tures has also been described.
Aged ; Female ; Humans ; Korea ; Rare Diseases ; Ulcer*

BACKGROUND: The afferent and efferent pathways of fentanyl cough response (FCR) and central organization are poorly understood at present. The aim of this study was to investigate the pretreatment effects of morphine, propofol, atropine, and midazolam on FCR. METHOD: The 120 healthy patients were randomly assigned to six equal pretreatment groups. They received 2ug/kg fentanyl rapidly through a peripheral venous catheter. The patients in each group were pretreated before the time necessary for peak plasma levels with different drugs as follows: group 1, no premedication; group 2, morphine 0.05 mg/kg iv; group 3, morphine 0.05 mg/kg iv naloxone 0.01mg/kg iv; group 4, propofol 0.5 mg/kg iv; group 5, atropine 0.01 mg/kg iv; group 6, midazolam 0.05 mg/kg iv. The patients were observed for any coughing or side effects, including oxygen desaturation, bronchoconstriction, chest wall rigidity and seizure. RESULT: 40% of patients in group 1 (control) had a cough response to fentanyl. Group 2 (morphine) and group 3 (morphine naloxone) showed a reduced FCR of 10%. The incidence of coughing was 60% of the patients in group 4 (propofol), 30% in group 5 (atropine), and 40% in group 6 (midazolam). These were not statistically significant. CONCLUSION: FCR is not altered by pretreatment with propofol, atropine, or midazolam, but morphine inhibits cough response and this antitussive effect was not antagonized by naloxone.
Atropine* ; Bronchoconstriction ; Catheters ; Cough* ; Efferent Pathways ; Fentanyl* ; Humans ; Incidence ; Midazolam* ; Morphine* ; Naloxone ; Oxygen ; Plasma ; Premedication ; Propofol* ; Seizures ; Thoracic Wall