1.The Role of NF-kappaB in the TNFalpha-induced Hyperplasia of Synoviocytes Isolated from Patients with Rheumatoid Arthritis.
Jee Hee YOON ; Sung Hee HWANG ; So Yeon MIN ; Ho Yeon KIM
Korean Journal of Immunology 2000;22(3):131-137
No abstract available.
Arthritis, Rheumatoid*
;
Humans
;
Hyperplasia*
;
NF-kappa B*
2.A asymptomatic rectal endometriosis with endometrial cyst.
Hyoung Min CHOI ; Sung Ki LEE ; Yoon Ho LEE ; Dong Hoon HWANG ; So Yeon PARK
Korean Journal of Obstetrics and Gynecology 1992;35(11):1679-1685
No abstract available.
Endometriosis*
;
Female
3.Restriction fragment length polymorphism analysis of varicella-zoster virus isolated in Korea.
Kyu Kye HWANG ; Song Yong PARK ; Sung Jin KIM ; Yeon Woo RYU ; Kyong Ho KIM
Journal of the Korean Society of Virology 1991;21(2):201-210
No abstract available.
Herpesvirus 3, Human*
;
Korea*
;
Polymorphism, Restriction Fragment Length*
4.Experimental Study On The Effect Of Hyperbaric Oxygen Therapy In Postirradiation Sialadenitis Of White Rats.
Journal of the Korean Association of Oral and Maxillofacial Surgeons 1999;25(1):1-12
Main objectives of this study were to produce the experimental postirradiation sialadenitis and to observe the effects of hyperbaric oxygen therapy after the production of postirradiation sialadenitis in the unilateral parotid gland of white rats. To produce the experimental postirradiation sialadenitis, author attempted the various methods of irradiation such as 1000rad weekly for 5 weeks, or single dosage of 2000rad, 3000rad, 5000rad, but those attempts were futile due to the high mortality of experimental animals(used 80rats for pilot study). Finally author had to design fractional irradiation, that is, 1000rad per 2 weeks, total 5000rad for 8 weeks in order to produce postirradiation sialadenitis. The occurrence of postirradiation sialadenitis was proved with serial salivary scan findings. Author used irradiation 1000rats, dividing into the control(50) and experimental group (50) and rendered the hyperbaric oxygen therapy(2 hours/daily at 2.4ATM) on the experimental group for 6 weeks. The effect of hyperbaric oxygen therapy was examined by salivary scan findings and microscopic examination. The obtained results of this study were as follows: 1. The differences of salivary gland function between irradiated parotid glands(right) and nonirradiated parotid glands(left) showed the most remarkable changes at 32 weeks after total 5000rad irradiation. 2. In microscopic examination at 32 weeks after total 5000rad irradiation, irradiated parotid glands(right) showed severe degenerative changes of acinar cells, separations of lobules due to edema, severe intralobular fibrosis and connective tissue fibrosis. 3. After hyperbaric oxygen therapy for 4 weeks, the effect of hyperbaric oxygen therapy showed no distinctive difference findings between the control and the experimental group with salivary scan findings(p>or=0.05), while the experimental group showed progressive intralobular edema, copillary proliferation, hyperemia in connective tissues and intralobular fibrosis in microscopic examination. 4. Tc99m uptake of the experimental group was raised after hyperbaric oxygen therapy for 6 weeks, and showed reduction of Tc99m uptake ratio between irradiated parotid gland and nonirradiated gland up to 8 to 10 weeks(p<0.05), while in the microscopic exemination the experimental group showed aggravated acinar cell degeneration, intercalated duct proliferation, connective tissues fibrosis. In this study, author speculated that though the hyperbaric oxygen therapy improved the capillary impairment, there was a tendency to increase the degenerative changes of parechyma of postirradiated parotid glands, thus the usage of the hyperbaric oxygen therapy should be considered carefully in the aspect of hazardous effect to the parotid parenchymal tissues.
Acinar Cells
;
Animals
;
Capillaries
;
Connective Tissue
;
Edema
;
Fibrosis
;
Hyperbaric Oxygenation*
;
Hyperemia
;
Mortality
;
Osteoradionecrosis
;
Oxygen
;
Parotid Gland
;
Rats*
;
Salivary Glands
;
Sialadenitis*
;
Xerostomia
5.Antimicrobial Susceptibilities and Serotypes of Group B Streptococci Isolated from Pregnant Women.
Young UH ; In Ho JANG ; Gyu Yel HWANG ; Kap Jun YOON ; Jang Yeon KWON ; Myeong Cheol KIM
Korean Journal of Clinical Pathology 1997;17(2):260-268
BACKGROUND: Recent data suggest that the colonization rate of group B streptococci(GBS) in pregnant women and the incidence of neonatal infections by GBS is increasing trend in Korea, but the antimicrobial susceptibilities and serotypes in pregnant women have not been reported in Korea. So, we studied to define the antimicrobial susceptibility patterns and frequency of serotypes of GBS in pregnant women. METHODS: The susceptibility and serotyping of 60 GBS isolates from 27 pregnant women and four isolates from their two neonates were tested by an agar dilution method and agglutination test, respectively. The typing sera used in this study were Ia, Ib, II, III, IV, and V. RESULTS: Minimal inhibitory concentration range of 60 GBS from pregnant women were penicillin G 0.015-0.12 microgram/ml, vancomycin 0.5-2 microgram/ml, clindamycin 0.015-4.0 microgram/ml, chloramphenicol 2-4 microgram/ml, erythromycin 0.015-2 microgram/ml, tetracycline 0.5-256 microgram/ml, cephalothin 0.12-0.25 microgram/ml, ceftriaxone 0.03-0.12 microgram/ml, respectively. The resistance rate of GBS were 6.7% to clindamycin, 0% to erythromycin, and 98.3% to tetracycline. Most of GBS serotypes from pregnant women in decreasing order were Ib(48.3%), Ia(24.1%), III(20.7%). CONCLUSION: All GBS strains isolated from pregnant women are highly susceptible to commonly used antimicrobial agents with the exception of tetracycline. The low prevalence of severe neonatal GBS infections in Korea is not due to the absence of serotype III, but probably due to a low genital carriage rate of GBS by pregnant women.
Agar
;
Agglutination Tests
;
Anti-Infective Agents
;
Ceftriaxone
;
Cephalothin
;
Chloramphenicol
;
Clindamycin
;
Colon
;
Erythromycin
;
Female
;
Humans
;
Incidence
;
Infant, Newborn
;
Korea
;
Penicillin G
;
Pregnant Women*
;
Prevalence
;
Serotyping
;
Tetracycline
;
Vancomycin
6.Extrapelvic endometriosis.
Ki Hong CHANG ; Hye Jeong YEON ; Kyoung Soo PARK ; Yoon Ho LEE ; Dong Hun HWANG
Korean Journal of Fertility and Sterility 1993;20(2):177-181
No abstract available.
Endometriosis*
;
Female
7.VERTICAL DIMENSION : A LITERATURE REVIEW.
The Journal of Korean Academy of Prosthodontics 1997;35(1):211-220
This article describes verticsal dimension in its histologic and clinical aspect. Determination of correct vertical dimension of occlusion is one of the most important steps in prosthodontic rehabilitation. It is considered essential for improvement of facial esthetics and stomatognatic functions. Many techniques have been sued for measurement of the vertical dimension in dentulous and edentulous patients : pre-extraction record, physiologic rest position, swallowing, phonetics, esthetics, etc. But, there is no universally accepted or completely accurate method. Though a great deal of energy has been spent trying to find the exact position of the mandible, there is an controversial aspect of vetical dimension.
Deglutition
;
Esthetics
;
Humans
;
Mandible
;
Phonetics
;
Prosthodontics
;
Rehabilitation
;
Vertical Dimension*
8.Reconstruction of Posterior Cruciate Ligament Using Bone-Patella Tendon-Bone Allograft - Two - to Four - Year Follow - Up Results.
Sung Do CHO ; Hyun Ho CHO ; Tae Woo PARK ; Su Min SON ; Su Yeon HWANG
Journal of the Korean Knee Society 2001;13(2):161-166
No Abstract Available.
Allografts*
;
Posterior Cruciate Ligament*
9.Myotonia Dystrophica: A Case Report
Joon Young KIM ; Young Joe KIM ; Byeong Yeon SEONG ; Moon Ho HWANG
The Journal of the Korean Orthopaedic Association 1985;20(1):195-199
Myotonia dystrophica(Synonym: Myotonia atrophica, Dystrophia myotonia, Steinert's disease) is a autosomal dominant hereditary multisystemic disorder involving several organs besides skeletal muscle, and commonly called with myotonia congenita, paramyotonia congenita as myotonia. Although most cases are of adult onset, where a mother has the disease, neonatal dystrophia myotonia can occur in her offspring. The main feature is a steadily progressive muscle dystrophy, complicated by myotonia, which is a failure of muscles to relax normally after a forceful contraction. Steinert in 1909 was the first to report the finding of atrophic testes and baldness in patients with myotonia dystrophica, and the other clinical feature of myotonia dystrophica were reported by many authors after that time. We are reporting a case of myotonia dystrophica, which showing familial history with brief review of literature.
Adult
;
Alopecia
;
Humans
;
Mothers
;
Muscle, Skeletal
;
Muscles
;
Myotonia Congenita
;
Myotonia
;
Myotonic Disorders
;
Myotonic Dystrophy
;
Testis
10.Surgical Treatment of Displaced Acetabular Fractures
Soo Ho LEE ; Key Yong KIM ; Yung Tae KIM ; Woo Yeon HWANG
The Journal of the Korean Orthopaedic Association 1994;29(5):1428-1437
Accurate anatomical reduction of the displaced acetabular fractures has a great clinical importance because acetabulum is related to weight-bearing and their fractures can lead to serious major sequelae. There are controversies and a lot of problems with regard to the management of the displaced acetabular fractures. The purpose of our study is to analyze the clinical results of operative treatment of the displaced acetabular fractures and to establish guidelines for treatment of their fractures. A clinical analysis was performed on 19 patients with displaced unstable acetabular fractures who had been operated on and followed for minimum 1 year period at Asan Medical Center from September 1989 to August 1992. The results were as follows: 1. The most common type was posterior wall fracture according to Letournel's classification. 2. Excellent or good results were obtained in 84% according to Goodwin's assessment method. All of the elementary fracture.s presented excellent or good results, while fair or poor results were observed in some T-shaped fractures or transverse and posterior wall fracture. 3. Complications were observed in 5 cases, including ectopic ossification(2 cases), traumatic arthritis(1 case), avascular necrosis of femoral head(1 case) and deep wound infection(1 case). Those seemed to be related with severe acetabular injury and extensive approach. 4. Kocher-Langenbeck approach was satisfactory for reduction and fixation of posterior column in transverse fracture, while extended iliofemoral approach was necessary for fixation of both column in T-shaped fracture. 5. Reduction of fracture of ilium was prerequisite for reduction of acetabular articular surface. 6. In displaced unstable acetabular fractures, early surgical intervention shich includes accurate anatomical reduction, and rigid internal fixation should be undertaken, and early joint motion should be followed to restore the joint function and to decrease the complication rate.
Acetabulum
;
Chungcheongnam-do
;
Classification
;
Humans
;
Ilium
;
Joints
;
Methods
;
Necrosis
;
Weight-Bearing
;
Wounds and Injuries