1.Indices of Insulin Resistance in Children with Simple Obesity.
Sung Yeon AHN ; Choong Ho SHIN ; Sei Won YANG
Journal of Korean Society of Pediatric Endocrinology 2004;9(1):42-49
PURPOSE:We performed this study to compare correlation between the indices of insulin resistance using fasting insulin and glucose level and body mass index (BMI), and to determine the clinical usefulness of glucose/insulin ratio (G/I ratio), which is easily available in clinical base. METHODS:Total 119 children with simple obesity, whose BMI is over 95th percentile, were evaluated. We calculated G/I ratio, logInsulin, HOMA-IR, logHOMA-IR, and QUICKI and evaluated their relationship to BMI. RESULTS:Children with high-degree obesity had higher insulin resistance than children with mild to moderate-degree obesity (logInsulin, 1.13+/-.23 vs 1.27+/-.29; logHOMA-IR, 0.46+/-.24 vs 0.61+/-.30; QUICKI, 0.33+/-.03, 0.31+/-.03)(P<0.01), and pubertal children had higher insulin resistance than prepubertal children (G/I ratio, 7.39+/-.07 vs 4.85+/-.29; logInsulin, 1.14+/-.27 vs 1.31+/-.22; logHOMA-IR, 0.47+/-.28 vs 0.65+/-.22; QUICKI, 0.33+/-.03 vs 0.31+/-.02) (P<0.001). BMI had correlation coefficient as -0.436 for QUICKI, -0.432 for G/I ratio, 0.430 for logInsulin, and 0.425 for logHOMA-IR (P=0.000). G/I ratio was well correlated with QUICKI (r=0.901, P=0.000), logHOMA-IR (r=-0.865, P=0.000), and logInsulin (r=0.899, P=0.000). The changes of BMI were correlated with changes of G/I ratio (r=-0.547, P<0.01), QUICKI (r=-0.464, P=0.01), and logHOMA-IR (r=0.429, P<0.05). CONCLUSION: This study revealed that the degree of BMI had statistically significant correlation with insulin resistance, which can be reflected by G/I ratio, logHOMA-IR and QUICKI. G/I ratio was well correlated with logHOMA-IR and QUICKI, which suggests that G/I ratio could be used as an bedside index of insulin resistance. The changes of G/I ratio were more correlated with changes of BMI than those of logHOMA-IR and QUICKI.
Body Mass Index
;
Child*
;
Fasting
;
Glucose
;
Humans
;
Insulin Resistance*
;
Insulin*
;
Obesity*
2.A histomorphometric study of dental implants with different surface characteristics.
Hyun Soon PAK ; In Sung YEO ; Jae Ho YANG
The Journal of Advanced Prosthodontics 2010;2(4):142-147
PURPOSE: One of the major keys to achieve successful osseointegration of the implant is its surface properties. The aim of this study was to investigate the bone response to dental implants with different surface characteristics using the rabbit tibia model. Tricalcium phosphate (TCP) coated, anodic oxidized and turned (control) surfaces were compared. MATERIALS AND METHODS: Seventy two implants were placed in the tibia of eighteen rabbits. Nine rabbits were sacrificed at 3 weeks of healing and the remaining nine were sacrificed at 6 weeks of healing. The bone-to-implant contact (BIC) and the bone volume density (BVD) were assessed by light microscope after 3 and 6 weeks of healing. RESULTS: Statistical analysis showed that no significant differences in the BIC and BVD were observed between the different implant surfaces and the control group at 3 weeks and 6 weeks of healing. Data also suggested that the BVD of all the surfaces showed significant difference at 3 and 6 weeks. CONCLUSION: The present study has showed that osseointegration occurred in all investigated types of surface-treated implants. In the current study all of the threads of the implants were observed to calculate BIC and BVD values (instead of choosing some of the threads from the bone cortex for example), which didn't make BIC or BVD percentage values better than in the control group, therefore the clinical relevance of these results remains to be shown.
Calcium Phosphates
;
Dental Implants
;
Light
;
Nitrogen Mustard Compounds
;
Osseointegration
;
Rabbits
;
Surface Properties
;
Tibia
3.Delayed Cutaneous Hypersensitivity Reactions in a General Adult Population of Korea.
Yang Soo NHO ; Young Ja CHOI ; Ho Suk SUNG
Korean Journal of Dermatology 1988;26(1):28-33
We messured delayed cutaneous hypersensitivity reactions by Multitest CMI Kit. Total 209 normal adults ranging in age from 17 to 55 year(male 106, female 103) were tested. The results were obtained as follows ; 1. Sum of average diameter of positive antigens wss 20.7mm in male and 15.6mm in female. 2. Number of positive antigens was 3.9 in male and 3.4 in female. 3. Rate of anergy was 1.4%(0.9% in male, 1.9% in female). 4. The rate of subjects below warning score(below 10mm in male, below 5mm in female) was 2.8% in male and 5.8% in female. 5. Antigen with the highest response was tuberculin in both sex(male 95.3%, female 89.3%) and antigen with the lowest response was trichophyton(22.5%). 6. Aversge score of positive response of every antigens was highest in tuberculin at both sex(male 2.8mm, female 2,6mm) 7. Average score of total antigens with positive response was 5.5mm in male and 4.6mm in female. 8. The rate of false positive reaction to 70% W/V glycerine was 1.4% totally.
Adult*
;
False Positive Reactions
;
Female
;
Glycerol
;
Humans
;
Hypersensitivity*
;
Korea*
;
Male
;
Tuberculin
4.A Case of Elastosis Perforans Serpiginosa Associated with Pseudoxanthoma Elasticum.
Yang Soo NHO ; Young Ja CHOI ; Ho Suk SUNG
Korean Journal of Dermatology 1987;25(3):422-426
we report a case of elastosis perforans serpiginosa associated with pseudoxanthoma e1asticurn on t:he neck of 27-year-old male patient. The lesions showecl erythematous scaly hyperkeratotic papules forming serpiginous pattern on yellowish elevated plaques. A skin biopsy specimen from the neck lesion revealed dense accurmulations of coarse elastic fibers partly cngulfed by epithelium in the papillary dcrrnis and increase cif short, irregulary clumped and degenerated clastic fibers in the middermis. On funduscopic exarnination, angioid streak is noted around the optic disk.
Adult
;
Angioid Streaks
;
Biopsy
;
Elastic Tissue
;
Epithelium
;
Humans
;
Male
;
Neck
;
Optic Disk
;
Pseudoxanthoma Elasticum*
;
Skin
5.A Case of Cystic Degeneration of Uterine Adenomyosis.
Yang Soo KWAK ; Sang Won LEE ; Ho Joon WHANGBO ; Doo Jin LEE ; Sung Ho LEE
Yeungnam University Journal of Medicine 1994;11(2):405-410
Adenomyosis is a common disease of middle-aged women and adenomyoma is a variety of adenomyosis that formed localized tumor. Cystic degeneration of an adenomyoma is a rare clinical manifestation. A 30-year-old parous woman suffered from severe dysmenorrhea and menorrhagia for about 5 months, was operated under the impression of endometriosis of the pelvis. Following the operation, cystic degeneration of an adenomyoma was found incidentally. The authors experienced a case of adenomyosis that formed cystic tumor of uterus and presented with a pertinent literatures.
Adenomyoma
;
Adenomyosis*
;
Adult
;
Dysmenorrhea
;
Endometriosis
;
Female
;
Humans
;
Menorrhagia
;
Pelvis
;
Uterus
6.Comparison of the Results of PCL Reconstruction using Bone-Patellar Tendon-Bone by Open Method and Arthroscopic Method.
Sung Ho HAHN ; Bo Kyu YANG ; Seung Rim YI ; Shun Wook CHUNG ; Sung Kyo SUH
The Journal of the Korean Orthopaedic Association 1999;34(5):923-929
PURPOSE: To compare the results of posterior cruciate ligament reconstruction by open and arthroscopic method. MATERIALS AND METHODS: From 1995 to 1997, 18 reconstructions of posterior cruciate ligament were performed. Group 1 (open method) was composed of 9 cases and group 2 (arthroscopic method) was consisted of 9 cases. After 21-month follow-up, The two groups were compared by clinical and radiologic methods. RESULTS: Clinically, Lysholm knee score was 80 points in group 1 and 83 points in group 2 after operation. Post operative results by Hughston's criteria were good in 5, fair in 2 and poor in 2 cases (group 1) and good in 6, fair in 2 and poor in 1 cases (group 2). Radiologically, post operative average of posterior drawer stress view was 5.2 mm (group 1) and 5.0 mm (group 2). Almost double the operation time was taken to reconstruct posterior cruciate ligament by arthroscopic method than open method. There were technical errors in 2 cases performed by arthroscopic method. CONCLUSIONS: The results of both methods had no significant difference. We think that the reconstruction of PCL using patellar tendon by open method is a recommendable treatment method together with arthroscopic method, if the merits or demerits of both methods are considered carefully. But more long-term follow-up is necessary to compare the results of PCL reconstruction by open and arthroscopic methods.
Follow-Up Studies
;
Knee
;
Patellar Ligament
;
Posterior Cruciate Ligament
7.The Significance of the Myelography in the Herniation of Intervertebral Disc
Kwon Ick HA ; Sung Ho HAHN ; Min Young CHUNG ; Yang Hee PARK ; Sung Jin CHO
The Journal of the Korean Orthopaedic Association 1987;22(4):908-913
The herniation of intervertebral disc is possibly diagnosed through the myelography, electromyography, discography or computerized tomography. Among them, the myelography is regarded as the popularized method that helps accurate analysis on the location and pattern of the lesion. The authors have studied 363 cases of herniated intervertebral disc with respect to the diagnostic accuracy of myelographic examination from January, 1982 to December, 1985 at the Department of Orthopedic Surgery and Radiology, National Police Hospital. The results were as follows; 1. The most common age group was 21 to 30 years old and ratio of male and female was 9.7: l. 2. The most common site of the lesion was between L4 and L5 vertebra in myelography. 3. Of the 363 cases which underwent the myelography, 305(84.0%) represented positive findings. 4. Myelographic accuracy was coincided with the clinical diagnosis regarding the location of herniation of intervertebebral disc in 262 cases(72.1%).
Diagnosis
;
Electromyography
;
Female
;
Humans
;
Intervertebral Disc
;
Male
;
Methods
;
Myelography
;
Orthopedics
;
Police
;
Spine
8.Entrapment Neuropathy of the Suprascapular Nerve by a Gangilion
Sung Ho HAHN ; Bo Kyu YANG ; Chi Hong KIM ; Tae Woe AHN ; Tae Sung KIM
The Journal of the Korean Orthopaedic Association 1996;31(3):564-568
Entrapment neuropathy of the suprascapular nerve is rare and frequently overlooked in the differential diagnosis of shoulder pain. There have been few published reports on a ganglion compressing the suprascapular nerve. We experienced a case of entrapment neuropathy of the suprascapular nerve by a ganglion that compressed the inferior branch of suprascapular nerve at the spinoglenoid notch.
Diagnosis, Differential
;
Ganglion Cysts
;
Shoulder Pain
9.Cellulitis in Young Adults.
Sung Ho HAHN ; Bo Kyu YANG ; Chi Hong KIM ; Tae Won AHN ; Sung Kyo SUH
The Journal of the Korean Orthopaedic Association 1998;33(3):614-619
While the microbiology of cellulitis in the pediatric population and systemic diseases(DM, Cirrhosis, etc) is well known,the causative bacteria and clinical aspect of cellulitis in young adults are less descrihed. this study was undertaken to identify the causative organisms and clinical aspect of adult cellulits. We analysed 121 medical records of 115 young adult patients with cellulitis who had been admitted at the department of orthopaedic surgery, National Police hospital from Jan. 1994. to Dec. 1996. The results were as follows. 1. The age of patient was between 21 yrs and 25 yrs, and the sex of all patients was male. 2. The lower leg and foot were the most frequently involved site of cellulitis as 92 cases(74.2%). 3. The potals were suspected in 65 cases(56.5%),of them, traumas were detected in 43 cases(66.1%), non-traumatic skin lesions in 23 cases(33.9%). 4. In most cases, initial systemic symptoms (fever, chill, headache, etc.) and local symptoms (local heating, tenderness, etc.) were found. 5. The laboratory findings revealed leukocytosis in 19%, elevated ESR in 94%, positive CRP in 80%. 6. Microorganism were detected in 16 of 38 pus cultures. Gram positive microorganisms were detected in 15 of 16 cases culture positive. 7. 6.7% of patients with cellulitis experienced recurrence in same lesions. In conclusion, the retrospective analysis of 115 young adult patients with cellulitis showed that primary cause of young adult cellulit was circulatory disturbance and lymphatic obstruction of the lower extremities most often involved by trauma. therefore, supportive treatments such as rest,elevation,ice packs are considered prior to antibiotic treatment.antibiotic treatment aimed at gram-positive cocci appears to be sufficient.
Adult
;
Bacteria
;
Cellulitis*
;
Fibrosis
;
Foot
;
Gram-Positive Cocci
;
Headache
;
Heating
;
Hot Temperature
;
Humans
;
Leg
;
Leukocytosis
;
Lower Extremity
;
Male
;
Medical Records
;
Police
;
Recurrence
;
Retrospective Studies
;
Skin
;
Suppuration
;
Young Adult*
10.A Case of Familial Multiple Polyposis of the Colon.
Chan Sup SHIM ; Seung Ho BAICK ; In Ho KIM ; Dong Ho YANG ; Sung Won CHO ; Hee Sook PARK
Korean Journal of Gastrointestinal Endoscopy 1986;6(1):43-47
Familial polyposis is inherited as an autosomal dominant trait. It is characterized by the progressive development of hundreds to thousands of adenomsteus polyps in the large intestine. A patient who inherited the gene for familial polyposis is asually asymptomatic until after puberty, at which time polyps begin to appear. The disease at first non-malignant but after an interval of a few months or years, the development of colon cancer is inevitable. In Korea, several cases were reported, but almost all of the cases had incomplete familial histories. We experienced one case of familial polypasis in 33-year old Korean male who had no malignant changes in the adenomatous polyps. Among his family, his father and his brother have adenomatous polps in the colon and the rectum confirmed through total colonoscopy with biopsy. We report a case of familial polyposis of colon with a brief review of literatures.
Adenomatous Polyposis Coli*
;
Adenomatous Polyps
;
Adolescent
;
Adult
;
Biopsy
;
Colon*
;
Colonic Neoplasms
;
Colonoscopy
;
Fathers
;
Humans
;
Intestine, Large
;
Korea
;
Male
;
Polyps
;
Puberty
;
Rectum
;
Siblings