1.A case of literature kluyvera sepsis in immunocompromised host.
Sun Ho CHANG ; Gyoo Rak LEE ; Jun Hee WOO
Korean Journal of Infectious Diseases 1991;23(2):113-115
No abstract available.
Immunocompromised Host*
;
Kluyvera*
;
Sepsis*
2.Positive rate of anti-HCV in patients with abnormal liver function test.
Ho Sun CHANG ; Joon Suh SONG ; Young Sik KIM
Journal of the Korean Academy of Family Medicine 1992;13(1):49-56
No abstract available.
Humans
;
Liver Function Tests*
;
Liver*
3.Genetic Heterogeneity in 56 kDa gene of Orientia tsutsugamushi Genotype Karp.
Woo Hyun CHANG ; Sun Ho KEE ; Hyun Jae SONG
Journal of the Korean Society for Microbiology 1997;32(4):415-420
The type-specific PCR and the sequence analysis of 56 kDa gene of Orientia tsutsugamushi infected in field rodents specimens have shown intratypic genetic heterogeneity in genotype Karp. In sequence comparison, this genetic heterogeneity was mainly due to insertion or deletion of a repeated unit in variable domain I (VDI) region. These results suggested that genetic duplication or deletion of the specific sequence rnight be involved in intratypic genetic heterogeneity of Orientia tsutsugamushi.
Genetic Heterogeneity*
;
Genotype*
;
Orientia tsutsugamushi*
;
Polymerase Chain Reaction
;
Rodentia
;
Sequence Analysis
4.The Clinical Significance of SCC, CEA and TPA as Tumor Markers in Cervical Cancer.
Chang Soo PARK ; Ho Sun CHOI ; Ji Soo BYUN
Korean Journal of Gynecologic Oncology and Colposcopy 1994;5(4):1-8
The clinical role of tumor markers to detect the extent of tumor invasion and recurrence in cervical cancer has been debated. To evaluate the chncal significance of SCC, CEA and TPA as tumor markers in cervical, we studied 744 patients weith cervieal cancer from June 1990 to Mey 1994. The cut-off val ues of SCC, CEA and TPA were 1.5 ng/ml, 4.5 ng/mi and 110 U/I respectively. Followings were the results. 1. The serum concentration and positive rates of SCC before therapy(567 cases) were 3,0+/-7.0ng/ml(40.4%) for stage I,8.7+/-13.9 ng/ml(71.6%) for stage II, 10.8+/-14.7 ng/ml(85.7%) for stage III, 23.9+/-24.3 ng/ml(94.7%) for stage IV, and 13.4+/-19.1 ng/ml(75.0%) for recurrent cancer. It was increased with advancing clinical stage(p<0.01). 2. The seum levels and positive rate of CEA before therapy(627cases) were 3.4+/-4.3 ng/ml (18%) for stage I, 7.1+/-12.3 ng/ml(37.2%) for stage II, 8.4+/-9.6 ng/ml(57.9%) for stage III, 15.4+/-22.2 ng/ml(52.6%) for stage IV, and 10.3+/-16.2 ng/ml(46.4%) for recurrent cancer. It was increased with advancing clinical stage from stage Ito stage III(p<0.01). 3. The serum concentration and positiceive rate of TFA before therapy(301cases) were 51.7+/-53.8 U/l(9.5%) for stage I, 105.3+/-108.8 U/l(32.3%) for stage II, 186.3%+/-159.8 U/l(50%) for stage III, 191.3+/-l06.2 U/I(63.6%) for stage IV, and 135.4+/-117.0 U/l(46.4%) for recurrent cancer. It was increased with advencing clinical stage(p<0.01). 4. In 64 patients{24.2%) with lymph node invasion of 265 patients treated by operation, the mean serum levels of SCC, CEA and TPA were higher than lymph node negative group(p<0.05). 5. The serum levels of SCCand CKA after therepy were 82.8% in sensitivity. 94.3% in specificity, 67.9% in positive predictive value, 97.4% in negative predictive value.
Humans
;
Lymph Nodes
;
Recurrence
;
Sensitivity and Specificity
;
Biomarkers, Tumor*
;
Uterine Cervical Neoplasms*
5.Passive Release of Pulley with Needle for Trigger Finger
Jung Man KIM ; Doo Hoon SUN ; Jung Ho CHANG
The Journal of the Korean Orthopaedic Association 1995;30(4):1027-1032
The purpose of this study was to assess the results of passive release of the pulley with needle under local anesthesia performed at the out patient department. There were 68 fingers of 54 patients. Fifteen patients(27.8 %) were male and 39 patients(72.2 %) were female. Involved fingers were 28 thumbs(41.2 %), 7(10.3 %) index fingers, 14(20.6 %) middle fingers, and 19(27.9 %) ring fingers. Ages were varied-between 41 years and 61 years old. Rheumatoid fingers were 12(17.6 %). The others had no underlying disease. An 18 gauge needle was introduced distal to the palpable nodule. The pulley was released passively when the PIP joint was extended. The follow-up period was 4.5 years on average(range; 1-8 years). At final follow-up local recurrence was noted in 1-2 weeks in 7 cases(10.3 %), which was due to technical fault in early trial cases. The patients complained of pain for a few days and mild tenderness for less than 2 weeks. In three cases adhesion occurred, which was resolved in a week by maniqulation. There was no difference between rheumatoid arthritis and the other underlying diseases as far as rate of recurrence was concerned. From these results it would be suggested that the passive release of pulley with needle is an effective method for the treatment of adult trigger finger.
Adult
;
Anesthesia, Local
;
Arthritis, Rheumatoid
;
Female
;
Fingers
;
Follow-Up Studies
;
Humans
;
Joints
;
Male
;
Methods
;
Needles
;
Recurrence
6.Preauricular pit-branchial sinus-hearing loss syndrome.
Sun O CHANG ; Chae Seo RHEE ; Seung Ho CHOI
Korean Journal of Otolaryngology - Head and Neck Surgery 1993;36(5):1043-1048
No abstract available.
7.Heart Rate Adjustment of ST Segment Depression as a Myocardial Ischemia Index of Coronary Artery Disease.
Sang Wook KIM ; Moo Sun CHANG ; Ho Jun YOO ; Ki Ik KWON ; Un Ho RYOO
Korean Circulation Journal 1993;23(5):676-683
BACKGROUND: Exercise testing is an importnat diagnostic and prognostic procedure in the assessment of patients with ischemic heart disease. But standard ST-segment depression criteria was not high enough to estimate coronary srtery disease. Recently, the heart rate adjustment of ST segment depression, ST segment/heart rate slope and index, have been proposed as a more accurate criteria for diagnosing significant coronary artery disease. The objective of this study was to compare the discriminating power of proposed ST segment/heart rate slope and index with that of a standard method of assessing exercise-induced ST segment depression for estimating coronary artery disease. METHODS: Sixty nine patients with ischemic heart disease were studied with exercise treadmill testing and coronary angiography. Computer-measured ST-segment amplitudes were obtained and analysis of the heart rate-adjusted ST segment depression(ST/HR slope and big up tri, Delta ST/HR index) was done. The sensitivity, specificity, and extent of coronary artery disease on each criteria were compared. RESULTS: 1) The sensitivity of big up tri, Delta ST/HR index partition of 1.6uV/beats/min was slightly higher(83%) and the specificity of ST/HR slope partition of 2.4uV/beats/min was higher(87%) than the standard exercise electrocardiographic criteria. 2) Early onset of ischemic ST-segment depression, profound ST-segment depression(> or =2mm), and downsloping ST-segment were associated with more extensive coronary artery disease. 3) On ST/HR slope, no CAD was 1.7+/-0.26uV/beats/min, one vessel disease was 2.6+/-0.34 uV/beats/min, two vessel disease was 2.7+/-1.36uV/beats/min, one vessel disease was 2.8+/-0.35uV/beats/min, and on big up tri, Delta ST/HR index, no CAD was 1.8+/-0.38uV/beats/min, one vessel disease was 2.8+/-1.36uV/beats/min, two vessel disease 3.4+/-1.44uV/beats/min, and three vessel disease was 3.7+/-2.95uV/beats/min. The increment of ST/HR slope and big up tri, Delta ST/HR index were associated with the coronary artery disease and its severity, but the correlations were not high enough. CONCLUSION: The heart rate adjustment of ST segment depression was not high enough for improved detection of coronary artery disease, compared with standard ST-segment depression criteria. But these indexes can be improved the clinical usefulness of the treadmill exercise test for coronary aretry disease.
Coronary Angiography
;
Coronary Artery Disease*
;
Coronary Vessels*
;
Depression*
;
Electrocardiography
;
Exercise Test
;
Heart Rate*
;
Heart*
;
Humans
;
Myocardial Ischemia*
;
Sensitivity and Specificity
8.Primary tuberculosis of the submandibular gland.
Ho Soo PYO ; Seoung Dae PAEK ; Jae Sun LIM ; Seong Ho CHUN ; Chang Won KIM
Korean Journal of Otolaryngology - Head and Neck Surgery 1991;34(1):193-197
No abstract available.
Submandibular Gland*
;
Tuberculosis*
9.Vasopressin gene expression in the rat hypothalamus studied by in situ hybridization and immunocytochemistry.
Sa Sun CHO ; Kyeong Han PARK ; Douk Ho HWANG ; ka Young CHANG ; Sang Ho BAIK
Korean Journal of Anatomy 1993;26(2):155-166
No abstract available.
Animals
;
Gene Expression*
;
Hypothalamus*
;
Immunohistochemistry*
;
In Situ Hybridization*
;
Rats*
;
Vasopressins*
10.Expression of Sialosyl Tn Mucin Antigen in Gastric Adenocarcinoma and Its Relationship with Prognostic Factors.
Sun Hee CHANG ; Ho Jung KIM ; Sun Hee SUNG ; Hea Soo KOO ; Woon Sub HAN
Korean Journal of Pathology 1999;33(9):695-701
Sialosyl Tn mucin antigen (STn) is a carbohydrate antigen of tumor associated mucin formed by the premature 2~6 sialation of N-acetylgalactosamine. STn has been expressed in several tumor types and showed prognostic significance in colonic carcinoma. The authors evaluated the expression of STn immunohistochemically and correlated its expression with clinicopathologic variables in 100 gastric cancers. In early gastric cancer, STn was expressed in 24 cases out of 50 cases (48%). In advanced gastric cancer, STn was expressed in 48 of 50 (96%). The difference in STn expression between advanced gastric cancer and early gastric cancer was statistically significant. The difference in STn expression between tumors with lymph node metastasis and those without lymph node metastasis, between tubular adenocarcinoma and signet ring cell carcinoma, and between intestinal type and diffuse type adenocarcinoma was statistically insignificant in early or advanced gastric adenocarcinoma. These results suggest that the STn expression plays a role in the tumor progression in both early and advanced gastric adenocarcinomas.
Adenocarcinoma*
;
Carcinoma, Signet Ring Cell
;
Colon
;
Lymph Nodes
;
Mucins*
;
Neoplasm Metastasis
;
Stomach
;
Stomach Neoplasms