2.Comparative Study of the Cervical Cytology, Colposcopic Impression and Directed Biopsy on the Role of the Diagnostic Approach to the Cervical Carcinoma.
Korean Journal of Gynecologic Oncology and Colposcopy 1994;5(1):56-63
A total of 369 patients with abnoirmal cervical eytology and suspicious lesions of the cervix were colposcoped end 356 patients of whom were, taken directed biopsy to assess the lesions preeisely and compare the aeeuracy of the eaeh methods. The results of cervical cytology were elso compared with the colpoacopic impression and colposcopically directed biopsies. 252 patients with abnr;irmal colyoaeopie findings were performl conization, simple hiysterectomy or radical hysterectomy depending on their current idisease statua. The rate of one grade less or more advanced correlation between the cervical cytology and directed biopsy was 72.4% and thiat of two grade less wns 80.3% and as for the correletion between the colposcopic imprwssions and the colposcopically directed biopsies, the rate of ciompatibility was 91.5%. Bases on the hetopathologic findings of the surgical apeeimen, the eompatibility rotcs of eervical cytology, colposcopic impressions and colposcopilIy divected hiopsies were 70.2%, 90.6% and 98.0% respectively. With these results, we can reach a conclusion that the colpnscopic impression itself is almost as accurate as the colposcopicolly directed biosy and the directed biopsy can take the place of conization so far as the diagnostic accuracy is concerned.
Biopsy*
;
Cervix Uteri
;
Conization
;
Female
;
Humans
;
Hysterectomy
3.Clinical Significance of N-Acetyl-beta-D-glucosaminidase in the Patients of Non-insulin-dependent Diabetes.
Korean Journal of Clinical Pathology 1997;17(1):47-54
BACKGROUND: Routine renal function tests are not sensitive enough to detect early renal complication of diabetes. To detect the complication as soon as possible, we measured urine N-Acetyl-beta-D-glucosaminidase(NAG) and evaluated in comparison with microalbumin and beta2-microglobulin(beta2-MG). METHODS: 87 patients with type II diabetes visited Catholic University Hospital of Taegu Hyosung during the period October 1995 to March 1996. We collected 24 hour urine samples and measured NAG, albumin excretion rate (AER), beta2-MG. urinalysis, BUN, creatinine(Cr) Cr clearance(CrCl), fasting and 2 hour postprandial blood sugar and hemoglobin A1c. RESULTS: The average age of the patients was 53+/-15 years old and their average disease duration was 5.8+/-5.0 years. Abnormal rates of each renal function tests were as follows : NAG/gCr 52.1%, AER 51.7%, CrCl 42.5%, BUN 18.4%, beta2-MG 13.8% and creatinine 6.9% in order. From 36 patients whose AER was within normal limit, 13 of them(36.1%) showed increased level of NAG/gCr. Of 38 patients with increased NAG/gCr results, the 31 patients (81.6%) recorded abnormal results of renal function tests. Among 87 patients studied 60 patients(68.5%) showed increased level of NAG/gCr or AER results. Compared with AER test alone. the combined tests with NAG/gCr increased 16.8% of detection rates of renal complication in type II diabetes. CONCLUSION: Urine NAG/gCr and AER tests were very useful for detecting the early renal complication of type n diabetes. As increase of NAG/gCr suggest the proximal tubule damage, it is necessary to have further evaluation about the proximal tubule damage of renal complication in type II diabetes.
Acetylglucosaminidase*
;
Blood Glucose
;
Creatinine
;
Daegu
;
Fasting
;
Humans
;
Urinalysis
4.A case of multifocal genital cancer associated with "HPV" infection.
Korean Journal of Obstetrics and Gynecology 1991;34(5):719-731
No abstract available.
5.A case of simultaneous presentation of uterine endometrial adenocarcinoma with right ovarian endometrioid carcinoma and left ovarian serous adenocarcinoma.
Seok Jin PARK ; Jun Yong HUR ; Ho Suk SUH
Korean Journal of Obstetrics and Gynecology 1991;34(8):1173-1178
No abstract available.
Adenocarcinoma*
;
Carcinoma, Endometrioid*
6.Detection of varicella-zoster virus DNA in clinical specimens by polymerase chain reaction(PCR).
Min Ho SUH ; Won Ki BAEK ; Kyu Suk LEE
Journal of the Korean Society for Microbiology 1991;26(5):479-486
No abstract available.
DNA*
;
Herpesvirus 3, Human*
7.A Study of Vascular Changes in the Lymph Nodes.
Hye Suk SONG ; Ho Won HWANG ; Chae Hong SUH
Korean Journal of Pathology 1985;19(2):179-186
A retrospective morphological study was conducted on 1677 lymph nodes which were removed surgically under the diagnosis of gastric carcinoma, breast carcinoma, colonic carcinoma, chronic gastric ulcer, and superficial lymph nodes nuder the diagnosis of reactive follicular hyperplasia at Chosun University Hospital during a period of 5 years from 1980 to 1984. The hematoxylin and eosin stained sections were examined to evaluate for any vascular changes. In selected cases further levels were prepared from the paraffin blocks for Gomori's reticulin stain. The vascular abnormalities were divided into 3 groups, such as hemangiomatoid, pan-nodal vasodilatation and miscellaneous types. The miscellaneous type included the proliferation of smooth muscle which encircled numerous small hilar arteries and veins. The results obtained were as follows: 1) The hemangiomatoid lesions were localized lesions which appeared to be associated with local malignancy, but infrequent in incidence. 2) A more frequent vascular abnormality was pan-nodal vasodilatation, which tend to affect many nodes in a single group and is relatively associated with chronic gastric ulcer. 3) Miscellaneous lesion was nonspecific and appeared both local malignancy and chronic inflammation. 4) All three vascular reactions were somewhat more frequent in female than male.
Female
;
Humans
;
Incidence
8.Detection of Human Papillomavirus DNA by In Situ Hybridization Using Biotinylated DNA Probes in Codylomata Acuminata.
Seok Ju KIM ; Kyu Suk LEE ; Joon Young SONG ; Seong Il SUH ; Min Ho SUH
Korean Journal of Dermatology 1990;28(6):702-707
Human Papillomaviruses(HPVs) are regarded as sexually transmitable and closely associated with precancerous lesions or invasive cancers of the vulva, vagina, and cer V1X. In situ hybridization, besides showing higher sensitivity, allowed the identification of specific viral types. We studied 12 cases of condylomata accuminata for HPV typing by in situ hybridization techenique. Ten cases(83.3 % ) showed positive for HPV type 6/11, and 2 cases(16.7% ) were positive for HPV type 16/18.
DNA Probes*
;
DNA*
;
Humans*
;
In Situ Hybridization*
;
Vagina
;
Vulva
9.In Vivo 1H MR Spectroscopic Imaging of Human Brain.
Yong Whee BAHK ; Kyung Sub SHINN ; Tae Suk SUH ; Bo Young CHOE ; Kyo Ho CHOI
Journal of the Korean Radiological Society 1994;31(2):185-190
PURPOSE: To evaluate the spatial distribution of various proton metabolites in the human brain with use of water-suppressed in vivo 1H MR spectroscopic imaging (MRSI) technique MATERIALS AND METHODS: All of water-suppressed in vivo 1H MRSI were performed on 1.5 T whole-body MRI/MRS system using Stimulated Echo Acquisition Method (STEAM) Chemical shift Imaging (CSI) pulse sequence. T1 -weighted MR images were used for CSl Field Of View (FOV; 24 cm). Voxel size of 1.S cm3 was designated from the periphery of the brain which was divided by 1024 x 16 x 16data points. RESULTS: Metabolite images of N-acetylaspartate (NAA), creatine/phosphocreatine (Cr) + choline/phosphocholine (Cho), and complex of gamma-aminobutyric acid (GABA) -I- glutamate (Glu) were obtained on the human brain. CONCLUSION: Our preliminary study suggests that in vivo 1H MRSl could provide the metabolite imaging to compensate for hypermetabolism on Positron Emission Tomography (PET) scans on the basis of the metabolic informations on brain tissues. The unique ability of in vivo 1H MRSI to offer noninvasive informations about tissue biochemistry in disease states will stimulate on clinical research and disease diagnosis.
Biochemistry
;
Brain*
;
Diagnosis
;
gamma-Aminobutyric Acid
;
Glutamic Acid
;
Humans*
;
Magnetic Resonance Imaging
;
Positron-Emission Tomography
;
Protons
10.Cutaneous Malignant Peripheral Nerve Sheath Tumor Not Associated with Neurofibromatosis.
Ha Na JUNG ; Woong Suk CHAE ; Ho Seok SUH ; Yu Sung CHOI
Korean Journal of Dermatology 2014;52(5):353-354
No abstract available.
Neurofibromatoses*
;
Peripheral Nerves*