1.Value of Dynamic MR Imaging in the Detection of Pituitary Microadenoma.
Song soo KIM ; Chang Jun SONG ; Ki ho JEONG ; Kil Jong YU
Journal of the Korean Radiological Society 2001;44(3):287-294
PURPOSE: To determine whether dynamic or conventional MR imaging is most useful for the detection of pituitary microadenoma. MATERIALS AND METHODS: The study involved 20 patients (M:F=1:19, mean age=37 years) in whom a pituitary microadenoma had been identified. Routine unenhanced coronal T1-weighted MR imaging was followed by dynamic imaging (repetition time/echo time/excitation=200/10/1, 3-mm-thick sections, 256X128 or 256 ma-trix,14X14-cm field of view, scan time=30 or 60 seconds, spin-echo pulse sequence), and contrast-enhanced coronal T1-weighted imaging was then immediately performed. Temporal changes in signal intensity were quantified with manually placed ROIs (regions of interest, circular, 3 mm 2), and tissue contrast between the pituitary gland and microadenoma was calculated. Conspicuity of the tumor margin was graded by three radiologists working independently as either 4 (excellent clear margin), 3 (good clear margin), 2 (relatively clear mar-gin), or 1 (unclear margin). RESULTS: Average peak enhancement of the pituitary gland and microadenoma occurred at 58.5 and 91.5 seconds, respectively. Maximum enhancement of the pituitary gland occurred within 30 to 60 seconds of contrast infusion (signal intensity range: 426-442), but during dynamic MR imaging, the microadenoma showed rela-tively constant enhancement (signal intensity range: 230 -250). Maximal contrast between normal pituitary gland and the microadenoma was seen at 60 seconds or in the first three sequential images. Dynamic MR images were superior to conventional T1-weighted images, with or without contrast infusion, not only in terms of tissue contrast between the pituitary gland and the microadenoma (p=0.0048), but also as regards tumor margin conspicuity (p=0.0035). CONCLUSION: Dynamic MR imaging is a useful technique in the detection of pituitary microadenoma.
Humans
;
Magnetic Resonance Imaging*
;
Pituitary Gland
2.Anal Fistula in Crohn's Disease.
Seok Won LIM ; Chul Ho LEE ; Kwang Real LEE ; Jung Jun YU
Journal of the Korean Society of Coloproctology 1997;13(1):101-109
Crypt glandular infection theory is accepted as an explanation of anal fistula's major cause. However, the pathogenesis of an anal fistula in Crohn's disease is different from that of a conventional anal fistula because a Crohn's anal fistula is caused by ulceration which, in turn, is caused by transmural inflammation of the rectal wall due to Crohn's disease. The difficulty with operating on anal fistulas in Crohn's disease lies in the fact that healing of the wound is inhibited because of continuous inflammation of the anorectal tissue due to Crohn's disease. Hence, there is a high possibility of incontinence due to sphincter muscle injury. Especially, because almost all Crohn's disease patients have frequent defecation and diarrhea, the patients will suffer more if incontinence occurs. Nowadays, even with increased understanding of the etiology of Crohn's disease, new medications, and aggressive surgical approaches, the result of treatment is still not satisfactory. Recently, since Korean eating habits have changed to include more western-style food in the diet, inflammatory bowel disease, such as Crohn's disease, is expected to increase. Consequently, the number of cases of anal fistulas in Crohn's disease is also expected to increase. The authors reviewed 20 confirmed cases of anal fistulas in Crohn's disease, which were treated from January 1993 to December 1995 at Song-Do Colorectal Hospital. The results are as follows: 1) Anal fistulas in Crohn's disease were present in 20(0.6%) of the 3378 cases of anal fistulas treated during the time period considered. 2) The male to female ratio for these 20 cases was 2: 1, and the most Prevalent age group was the 3rd decade, followed by the 2nd decade, the 4th decade, and the 5th decade in that order. 3) Three cases of anal fistulas whose origins could be explained by crypt glandular infection theory and which did not involve the rectum healed, although the healing was delayed. 4) Seventeen cases of anal fistulas whose origins could not be explained by crypt glandular infection theory and which involved the rectum did not heal after the operation. he results of the study show that anal fistulas whose origins can be explanined by crypt glandular infection theory and which do not involve the rectum can be cured by conventional fistula surgery. However, perirectal fistulas whose origins can not be explained by crypt glandular infection theory and which involve the rectum do not heal. Because there is the possibility of incontinence after a conventional operation, it is suggested that, in the cases of perirectal fistulas in Crohn's disease, better results, although not completely satisfactory, can be obtained by long-term seton drainage and diversion colostomy.
Colostomy
;
Crohn Disease*
;
Defecation
;
Diarrhea
;
Diet
;
Drainage
;
Eating
;
Female
;
Fistula
;
Humans
;
Inflammation
;
Inflammatory Bowel Diseases
;
Male
;
Rectal Fistula*
;
Rectum
;
Ulcer
;
Wounds and Injuries
3.Renal Cell Carcinoma in Patients on Dialysis for End-Stage Renal Disease.
Korean Journal of Nephrology 2011;30(3):351-354
No abstract available.
Carcinoma, Renal Cell
;
Dialysis
;
Humans
;
Kidney Failure, Chronic
4.Prostaglandin E2 and F2?concentrations in human oviductal tissue during different phases of the menstrual cycle.
In Sook SOHN ; Chan Ho SONG ; Ki Hyun PARK ; Young Ja PARK ; Kyung Ja YU
Korean Journal of Obstetrics and Gynecology 1993;36(7):2262-2269
No abstract available.
Animals
;
Dinoprostone*
;
Female
;
Humans*
;
Menstrual Cycle*
;
Oviducts*
5.Report of the Korean Journal of Urology Editorial Board Meeting 2014.
Korean Journal of Urology 2014;55(12):773-774
No abstract available.
*Editorial Policies
;
Humans
;
Journal Impact Factor
;
Periodicals as Topic/*statistics & numerical data
;
Republic of Korea
;
Urology/*statistics & numerical data
6.A Case of Congenital Rubella Syndrome.
Jin Ho YU ; Young Ho KWAK ; He Sun JUNG ; Song Yi NA ; Hoan Jong LEE ; Ki Joon SONG
Korean Journal of Infectious Diseases 1999;31(5):439-444
Congenital rubella syndrome is a transplacental fetal infection with rubella virus and shows a wide spectrum of clinical expression from severe malformation to asymptomatic in the neonatal period. For the confirmation of congenital rubella, one of the following laboratory criteria should be present: isolation of rubella virus, demonstration of rubella-specific IgM antibody, or a rubella IgG antibody that persists and fails to drop at a rate of twofold dilution per month. Recently a reverse transcription-nested polymerase chain reaction (RT-nPCR) method for the prenatal diagnosis of rubella virus infection has been used. We experienced a case of congenital rubella in a 15- month old male who had suffered from respiratory difficulty. He had low birth weight. Thrombocytopenia was noticed shortly after his birth. He was transferred to our hospital because persistent respiratory difficulty had been developing since the age of one month. His growth and development were delayed. Physical examination revealed micrognathia, hepatosplenomegly, lymphadenopathy, and petechiae. Laboratory examination revealed a rubella specific IgM antibody. Chest X-ray suggested a chronic lung change. Rubella virus RNA was detected in the serum by RT-nPCR. This is the first case of congenital rubella, which was confirmed by the detection of rubella virus RNA, in Korea.
Growth and Development
;
Humans
;
Immunoglobulin G
;
Immunoglobulin M
;
Infant, Low Birth Weight
;
Infant, Newborn
;
Korea
;
Lung
;
Lymphatic Diseases
;
Male
;
Parturition
;
Physical Examination
;
Polymerase Chain Reaction
;
Prenatal Diagnosis
;
Purpura
;
RNA
;
Rubella
;
Rubella Syndrome, Congenital*
;
Rubella virus
;
Thorax
;
Thrombocytopenia
7.A Case of Congenital Rubella Syndrome.
Jin Ho YU ; Young Ho KWAK ; He Sun JUNG ; Song Yi NA ; Hoan Jong LEE ; Ki Joon SONG
Korean Journal of Infectious Diseases 1999;31(5):439-444
Congenital rubella syndrome is a transplacental fetal infection with rubella virus and shows a wide spectrum of clinical expression from severe malformation to asymptomatic in the neonatal period. For the confirmation of congenital rubella, one of the following laboratory criteria should be present: isolation of rubella virus, demonstration of rubella-specific IgM antibody, or a rubella IgG antibody that persists and fails to drop at a rate of twofold dilution per month. Recently a reverse transcription-nested polymerase chain reaction (RT-nPCR) method for the prenatal diagnosis of rubella virus infection has been used. We experienced a case of congenital rubella in a 15- month old male who had suffered from respiratory difficulty. He had low birth weight. Thrombocytopenia was noticed shortly after his birth. He was transferred to our hospital because persistent respiratory difficulty had been developing since the age of one month. His growth and development were delayed. Physical examination revealed micrognathia, hepatosplenomegly, lymphadenopathy, and petechiae. Laboratory examination revealed a rubella specific IgM antibody. Chest X-ray suggested a chronic lung change. Rubella virus RNA was detected in the serum by RT-nPCR. This is the first case of congenital rubella, which was confirmed by the detection of rubella virus RNA, in Korea.
Growth and Development
;
Humans
;
Immunoglobulin G
;
Immunoglobulin M
;
Infant, Low Birth Weight
;
Infant, Newborn
;
Korea
;
Lung
;
Lymphatic Diseases
;
Male
;
Parturition
;
Physical Examination
;
Polymerase Chain Reaction
;
Prenatal Diagnosis
;
Purpura
;
RNA
;
Rubella
;
Rubella Syndrome, Congenital*
;
Rubella virus
;
Thorax
;
Thrombocytopenia
8.Polyarteritis Nodosa in the Stomach: A Case Report.
Ho Jun YU ; June Sik CHO ; Kyung Suk SHIN ; Kyu Sang SONG
Journal of the Korean Radiological Society 2000;42(3):505-507
Polyarteritis nodosa is a systemic inflammatory disease resulting from necrotizing angitis of small to medium sized arteries. It involves various organs, including the gastrointestinal tract, which is involved in about 50% of all cases. Numerous complications-including abdominal pain, vomiting, and hematemesis-have been reported, but the CT findings have not been described. We report the CT findings in a case of gastric polyarteritis nodosa, and correlate these with the histopathologic findings.
Abdominal Pain
;
Arteries
;
Arteritis
;
Gastrointestinal Tract
;
Polyarteritis Nodosa*
;
Stomach*
;
Vomiting
9.Correlation between Heart Rate Variability and Sleep Structure in Primary Insomnia.
Sang Jin LEE ; Doo Heum PARK ; Jaehak YU ; Seung Ho RYU ; Ji Hyeon HA ; Man Kyoo SONG
Sleep Medicine and Psychophysiology 2010;17(1):21-27
OBJECTIVES: It is well established that primary insomnia affects the activity of autonomic nervous system. We tried to know how the activity of autonomic nervous system during night sleep changes by analyzing correlation between heart rate variability (HRV) index and the variables related with sleep structure in primary insomnia. METHODS: Thirty three subjects (mean age:36.2+/-14.2 years, male:female=15:18) who were diagnosed with primary insomnia were selected for the study. Nocturnal polysomnography (NPSG) was carried out on each subject and correlation was analyzed between high frequency/low frequency ratio (LF/HF ratio), one of HRV indices and the variables related with sleep structure which were calculated from NPSG. RESULTS: When age and sex were controlled, LF/HF ratio showed negative correlations with slow wave sleep and stage 2 sleep, respectively (r(p)=-0.43, p=0.01;r(p)=-0.37, p=0.04). On the other hands LF/HF ratio showed a positive correlation with arousal index (r(p)=0.65, p<0.001). The activity of autonomic nervous system responded differentially depending on the change of sleep structure in primary insomnia. Especially the increase of arousal index and the decrease of slow wave sleep and stage 2 sleep which are the components of non-REM sleep provoked hyperactivity of sympathetic nervous system. CONCLUSION: This study suggests that the typical change of sleep structure in primary insomnia can negatively impact on cardiovascular system.
Arousal
;
Autonomic Nervous System
;
Cardiovascular System
;
Hand
;
Heart
;
Heart Rate
;
Polysomnography
;
Sleep Initiation and Maintenance Disorders
10.The Effect of the Mother-Child Development Promotion Program for the Child with Developmental Delay on Mother's Depressive Mood and Parenting Stress.
Hong Sup YU ; Soon Jeong LEE ; Dong Ho SONG
Journal of the Korean Academy of Child and Adolescent Psychiatry 2009;20(3):152-157
OBJECTIVES: We investigated the parenting stress and depressive mood of mothers with developmentally-delayed children and the effects of participation in a mother-child development promotion program on same. METHODS: Subjects were the mothers of 20 developmentally-delayed children. The severity of the mothers' parenting stress was evaluated via the Korean version of the Parenting Stress Index, Short Form (K-PSI-SF) and the severity of their depressive symptoms were evalueted by the Korean version of the Beck Depression Inventory (K-BDI). RESULTS: The mean K-PSI-SF score and mean K-BDI score for these mothers were 93.35 (SD=10.47) and 23.25 (SD=10.42), respectively. These scores correspond to high parenting stress and moderate depression. The mothers who participated in a mother-child attachment- promotion program showed significant decreases in their K-PSI-SF and KBDI scores. CONCLUSION: Our data suggest that a mother-child attachment promotion program with emphasis on child development is effective in reducing parenting stress and depressive mood in mothers of developmentally-delayed children.
Child
;
Child Development
;
Depression
;
Humans
;
Mothers
;
Parenting
;
Parents