1.A Case of Pityriasis Rotunda Associated with Adenocarcinoma of Pancreas.
Yean Sub JANG ; Seok Ho KIM ; Eil Soo LEE
Korean Journal of Dermatology 1987;25(6):782-785
We report a case of pityriasis rotunda occurring in a patient with pancreatic adenocarcinoma. The patient was a 64-year old female who had a pancreatic adenocarcinoma. The skin lesions were asymptomatic, multiple, various sized (1 to 15cm in diameter), isolated or confluent and finely scaly light brownish to grayish colored patches on the lower abdomen, back and thigh. Histopathologic findings shawed mild hyperkeratosis, atrophy, loss of granular layer, increased melanin pigments in basal layer of the epidermis and mild perivascular monocytic infiltration in the upper dermis.
Abdomen
;
Adenocarcinoma*
;
Atrophy
;
Dermis
;
Epidermis
;
Female
;
Humans
;
Melanins
;
Middle Aged
;
Pancreas*
;
Pityriasis*
;
Skin
;
Thigh
2.Ketamine Use of Pediatric Sedation in Emergency Room.
Jeong Pill SEO ; Jun Seok PARK ; Tae Sik HWANG ; Seok Joon JANG ; Seung Ho KIM
Journal of the Korean Society of Emergency Medicine 2000;11(3):339-344
BACKGROUND: Ketamine use in emergency room has been increased. It has rapid onset of action and appropriate duration of action. It does not need endotracheal intubation and produces potent analgesia, sedation, and amnesia. The object of this study is to determine the safety and the degree of physician's satisfaction in relation to ketamine use. MATERIALS AND METHODS: This is a prospective study using protocol. Pediatric trauma patients who need sedation were given IM ketamine(4mg/kg) and atropine(0.01mg/kg) in a same syringe. Monitoring of patients was done by EM residents and complications of ketamine use were recorded. Physician's satisfaction was also recorded after the procedure. RESULTS: Intramuscular ketamine was administered 54 times, mainly for laceration repair. Physicians completed protocol for 51 of treated children. The median time for onset of sedation was 6.5+/-2.4 min, and duration of action was 32.4+/-10.8 min. Hypersalivation occurred in 9.8%(n=5); random movement 3.9%(n=2), emesis during procedure(n=1), emesis at home(n=1), and transient oxygen desaturation(n=1). All were quickly identified and treated without specific airway management and sequelae. Of 84% of physicians was satisfied with ketamine use for pediatric sedation. CONCLUSION: Intramuscular ketamine can be administered safely and satisfactorily in emergency room to facilitate pediatric procedures in conjunction with a defined protocol and appropriate monitoring.
Airway Management
;
Amnesia
;
Analgesia
;
Child
;
Emergencies*
;
Emergency Service, Hospital*
;
Humans
;
Intubation, Intratracheal
;
Ketamine*
;
Lacerations
;
Oxygen
;
Prospective Studies
;
Sialorrhea
;
Syringes
;
Vomiting
3.Comparative Quantitative Study of Surfactant Protein C mRNA by Filter Hybridization and Solution Hybridization in Rats.
Jin Ho KIM ; Jang Won SOHN ; Seok Chul YANG ; Ho Joo YOON ; Dong Ho SHIN ; Sung Soo PARK
Tuberculosis and Respiratory Diseases 2001;51(6):517-529
BACKGROUND: Surfactant protein C(SP-C) is a hydrophobic 5,000 dalton molecule. SP-C has the primary roles in accelerating surface spreading of a surfactant phospholipid. The filter hypbridization and solution hybridization assays are both rapid and sensitive and can be used to measure the RNAs complementary to any cloned DNA sequence. METHODS: The authors measured the SP-C mRNA levels quantitatively using solution hybridization and filter hybridization assays to obtain a standard curve equation to quantify the mRNA of unknown samples comparatively. RESULTS: 1. The minimum level of the specimens by solution hybridization was 3 pg for SP-C mRNA. 2. The standard curve equation of the solution hybridization assay between the counts per minute(Y) and the SP-C mRNA transcript input(X) was Y=6.46 X+244. The correlation coefficient was 0.9. 3. The minimum detection level of specimens by filter hybridization was 0.1 ng for SP-C mRNA. 4. The standard curve equation of the filter hybridization assay between the counts per minute(Y) and SP-C mRNA transcript input(X) is Y=2541.6 X+252.7. The correlation coefficient was 0.99. CONCLUSION: A comparison of CPM/filter in the linear range allowed an accurate and reproducible estimation of the SP-C mRNA copy number. Filter hybridization and solution hybridization assays are both rapid and sensitive and can be used to measure the RNAs complementary to any cloned DNA sequence. It is ideally suited to situations where accurate quantitation of multiple samples is required.
Animals
;
Base Sequence
;
Clone Cells
;
Protein C*
;
Rats*
;
RNA
;
RNA, Messenger*
4.The Effect of Pamidronate on Prevention of Osteoporosis in Ovariectomized Rats.
Jang Seok CHOI ; Seung Seok SEO ; Jong Ho PARK ; Kyu Min KONG
Journal of Korean Orthopaedic Research Society 1998;1(1):115-123
Many agents for the treatment of osteoporosis are broadly classified as inhibitors of bone resorption and stimulators of bone formation. Many pharmacological derivatives of bisphosphonates are used in the treatment of osteoporosis by inhibiting osteoclast-mediated bone resorption. Although the pamidronate, derivative of bisphosphonates, has a potent antiresorptive activity, there are only a low reports about prevention and treatment of postmenopausal osteoporosis using it. The purpose of this study is to evaluate the changes of bone metabolism and bone mass after pamidronate administration during the early period of estrogen deficiency. Ninty-five Sprague-Dawley rats (weight 233-243 g) were divided into 3 groups. Group 1(n=28) was performed sham operation. Group 2 (n=25) was both ovariectomized and intravenously injected with 0.5 cc normal saline. Group 3 (n=42) was both ovariectomized and intravenously injected with 0.1 mg/kg pamidronate. During the first 8 weeks normal saline or pamidronate was intravenously injected twice a week(q 3 day or q 4 days). After 4 weeks of observation without injection the experiental animals were sacrificed at postoperative 12 weeks. There were statistically significant decrease in the body weight and the weight of uterus in group 1 compared with group 2, 3. There was statistically significant decrease in the bone mass of the spine, proximal femur, proximal tibia in the group 2 compared with group 1, 3. The difference of bone mass between group 1 and 3 was statistically insignificant. Serum osteocalcin and PICP concentration were significantly increased in group 2 and 3 compared with group 1. But there was no statistical significance between group 2 and 3 in serum osteocalcin and PICP concentration. Serum ICTP concentration was significantly decreased in group 1 and 3 compared with group 2, but the difference between group 1 and 3 was insignificant. These results suggests that the administration of the pamidronate during the early period of estrogen deficiency can inhibit bone resorption and prevent trabecular bone loss of the spine, proximal femur and proximal tibia metabolically.
Animals
;
Body Weight
;
Bone Resorption
;
Diphosphonates
;
Estrogens
;
Female
;
Femur
;
Humans
;
Metabolism
;
Osteocalcin
;
Osteogenesis
;
Osteoporosis*
;
Osteoporosis, Postmenopausal
;
Ovariectomy
;
Rats*
;
Rats, Sprague-Dawley
;
Spine
;
Tibia
;
Uterus
5.Corrigendum: Moderate and Deep Hypothermia Produces Hyporesposiveness to Phenylephrine in Isolated Rat Aorta.
Jun Woo CHO ; Chul Ho LEE ; Jae Seok JANG ; Oh Choon KWON ; Woon Seok ROH ; Jung Eun KIM
The Korean Journal of Thoracic and Cardiovascular Surgery 2014;47(1):75-75
There was an error in article.
6.A Case of Septo-Optic Dysplasia.
Young Seok CHO ; Eun Young JANG ; Byung Ho CHA ; Baek Keun LIM
Journal of the Korean Child Neurology Society 1998;5(2):393-397
Septo-optic dysplasia, as first described by de Morsier, is a rare developmental anomaly of absent or hypoplastic septum pellucidum, a primitive optic vesicle, and dysplasia of the optic nerve, chiasm, and optic tracts. It is a common cause of hypopituitarism in children and has variable hypothalamic-pituitary dysfunction. We experienced a case of septo-optic dysplasia in 5 month old female baby who presented with developmental delay and seizure. A magnetic resonance imaging of the brain showed absence of the septum pellucidum and the fundoscopic examination disclosed the absence of left optic disc and atrophy of right optic disc.
Atrophy
;
Brain
;
Child
;
Female
;
Humans
;
Hypopituitarism
;
Infant
;
Magnetic Resonance Imaging
;
Optic Nerve
;
Seizures
;
Septo-Optic Dysplasia*
;
Septum Pellucidum
;
Visual Pathways
7.A Case of Lateral Ventricle Choroid Plexus Papilloma in a Child.
Eui Joong YANG ; Seok Joong JANG ; Ho SHIN
Journal of Korean Neurosurgical Society 1990;19(5):693-698
The choroid plexus papillomas are uncommon neoplasms of the central nervous system, and constitute 0.5~0.6 percent of intracranial tumors. These tumor are surgically treatable and the encouraging results of surgical removal justify an aggeressive surgical approach. We present a case of lateral ventricle choroid plexus papilloma in a child with communicating hydrocephalus.
Central Nervous System
;
Child*
;
Choroid Plexus*
;
Choroid*
;
Humans
;
Hydrocephalus
;
Lateral Ventricles*
;
Papilloma, Choroid Plexus*
8.APPLICATION OF SLIDING TRANSPOSITION FLAP ON LOWER LEG DEFECTS.
Jang Ho KIM ; Kun HWANG ; Minn Seok KIL ; Chung Jea LEE ; Se Il LEE
Journal of the Korean Society of Plastic and Reconstructive Surgeons 1997;24(4):799-806
No abstract available.
Leg*
9.The analysis of discharge against medical advice in the emergency department.
Seung Whan KIM ; Ok Jun KIM ; Seok Joon JANG ; Koo Young JUNG ; Seung Ho KIM
Journal of the Korean Society of Emergency Medicine 1993;4(2):116-122
No abstract available.
Emergencies*
;
Emergency Service, Hospital*
10.No title available in English.
Jong Ho YOON ; Kee Hyun NAM ; Hang Seok JANG ; Cheong Soo PARK
Korean Journal of Endocrine Surgery 2004;4(2):127-128
No abstract available.