2.Morphological evidence of mitotic activity of mammotrophs and somatotrophs in monolayer cultured rat anterior pituitaries.
Eun Young LEE ; Byung Lan LEE ; Chung Ik CHA ; Sa Sun CHO ; Sang Ho BAIK
Korean Journal of Anatomy 1993;26(1):3-16
No abstract available.
Animals
;
Rats*
;
Somatotrophs*
3.A Percutaneous Cross Pinning Method for Supracondylar Fracture of the Humerus : The Significance of Elbow Position during Pinning to Avoid Ulnar Nerve Damage
Jong Deuk RHA ; Myung Ho LEE ; Hyun Soo PARK ; Woo Cheon LEE ; Tong Hoon SA
The Journal of the Korean Orthopaedic Association 1995;30(5):1404-1407
The percutaneous pinning is a simple, effective method for the treatment of displaced supracondylar fractures of the humerus in children. But there is some controversy in the number of pins used and the method of pin insertion. The cross pinning method provides more stability at the fracture site but the risk of ulnar nerve damage is higher than in lateral pinning method, The senenty-one displaced extension type supracondylar fractures were treated by closed reduction and percutaneous cross pinning from January 1991 to October 1994. Among them, the medial pin was inserted in elbow extension in twenty-eight cases and in forty- three cases the medial pin was inserted in elbow flexion. Ulnar nerve injury occured postoperatively in six cases, in which the pin was inserted with the elbow in flexion position. These results may suggest that when percutaneous cross pinning method is selected to fix the supracondylar fracture of the humerus, it would be safer to insert one or two lateral pins with the elbow in full flexion position followed by one medial pin in extension position in order to reduce the risk of loss of reduction and ulnar nerve damage.
Child
;
Elbow
;
Humans
;
Humerus
;
Methods
;
Ulnar Nerve
4.A clinical study on neonatal seizures.
Bong Sik KONG ; Ri Sa LEE ; Sang Kyu PARK ; Ho Jin PARK
Journal of the Korean Pediatric Society 1991;34(2):230-239
No abstract available.
Seizures*
5.Three Cases of Late Hemorrhagic Disease of Ingancy.
Yang Su KANG ; Ree Sa LEE ; Sang Kyn PARK ; Ho Jin PARK ; Mi Ja SHIN
Journal of the Korean Pediatric Society 1989;32(7):1001-1006
No abstract available.
6.Plastination: An Improved Method for Preservation of Pathology Specimens.
Chong Woo YOO ; Min Ho CHOO ; Sa Sun CHO ; Sang Kook LEE ; Je Geun CHI ; Woo Ho KIM
Korean Journal of Pathology 1998;32(7):531-534
The gross tissue specimens are a valuable aid to the teaching of pathology and anatomy. However, traditional methods for storage and handling of them are discouragingly difficult and, recently, minimal surgical resections as well as preoperative interventions make it more difficult to have instructive gross specimens. Plastination is a process of tissue preservation by impregnation with silicone polymers or epoxy resins. The process in our study involves dehydration by cryosubstitution in aceton, defatting, forced impregnation of silicon polymer in a vacuum, curing and finishing. We submitted 40 surgically resected specimens to plastination. The resulting specimens are odorless, relatively dry, durable, life-like, non-hazardous, maintenance-free, and do not deteriorate with time. Plastinated specimens are a useful adjunct to the teaching of pathology, particularly suited for use in small groups, and appropriate method of tissue preservation. They are much preferred to wet preparation and conventional pots by both students and teachers owing to their accessibility, superior illustrative powers, and comparative ease of interpretation.
Dehydration
;
Epoxy Resins
;
Humans
;
Pathology*
;
Polymers
;
Silicones
;
Tissue Preservation
;
Vacuum
7.Comparison of Diagnostic and Therapeutic Efficacy between Ultrasound Guided Hydrostatic Saline Reduction and Fluoroscopic Barium Reduction in Children with Intussusception.
Chi Hyung PARK ; Ho Seok LEE ; Chong Woo BAE ; Sa Jun CHUNG ; Young Mook CHOI ; Sun Wha LEE ; Yup YUN
Journal of the Korean Pediatric Society 1995;38(12):1664-1670
No abstract available.
Barium*
;
Child*
;
Humans
;
Intussusception*
;
Ultrasonography*
9.Immunohistochemical Study on the Changes of Neuropeptide Y Immunoreactive Neurons in the Corpus Striatum and Motor System of Aged Rat.
Jung Ik CHA ; Jin Joo HONG ; Young Il LEE ; Byung Ran LEE ; Sa Sun JO ; Sang Ho BAEK
Korean Journal of Anatomy 1997;30(3):215-224
Decreased number of the Neuropeptide-Y[NPY] immunoreactive neurons in the corpus striatum and primary motor cortex of aged rat was detected by the immunohistochemical method. The animals were categorized into control and aged group and we used 10 Sprague-Dawley rat weighing 250-300gm for control group. 10 Sprague-Dawley rat weighing over 600gm for aged group. The number of NPY-immunoreactive neurons in corpus striatum and primary motor cortex were counted under the light microscope and the following results were obtained. 1. The NPY-immunoreactive neurons were evenly distributed in corpus striatum and in the primaty motor cortex, the NPY-immunoreactive neurons were concentrated within the layer II, III and layer V, VI. The typical NPY-immunoreactive perikarya was multipolar shape. 2. Decreased number of NPY-immunoreactive neurons were detected in some areas of corpus striatum and primary mortor cortex of the aged rat. 3. Decrease of NPY-immunoreactive neurons were most prominent in the caudate-putamen and there were moderate decrease of NPY-immunoreactive neurons in the primary motor cortex, mild decrease of NPY-immunoreactive neurons in the nucleus accumbens but the NPY-immunoreactive neurons were not observed in the globus pallidus in both control and aged rat. NPY is supposed to act as a neurotransmitter of local circuit neurons in the striatum and may exert its potent vasoconstrictor effects on cerebral vessels which influences on the microcirculation of cerebral cortex and striatum. So our results seems to provide an important data on change of the function in the striatum and primary motor cortex of aged rat brain.
Aging
;
Animals
;
Brain
;
Cerebral Cortex
;
Corpus Striatum*
;
Globus Pallidus
;
Microcirculation
;
Motor Cortex
;
Neurons*
;
Neuropeptide Y*
;
Neuropeptides*
;
Neurotransmitter Agents
;
Nucleus Accumbens
;
Rats*
;
Rats, Sprague-Dawley
10.Immunochemical Study on the Changes of Carbonic anhydrase-II and Iron-binding Proteins in the Demyelinationand and Remyelination model Mouse induced with Cuprizone.
Gyung Hoon LEE ; Hwa Young LEE ; Young Bok YOO ; Dong Hoon SHIN ; Sang Ho BAEK ; Sa Sun JO
Korean Journal of Anatomy 1997;30(6):683-694
O1igodendrocytes are known to be responsible for the synthesis and maintenance of myelin sheath in the central nervous system, and their functional disturbance leads to defect in myelination. But, the fine mechanism of myelination by oligodendrocytes is not yet known, and iron metabolism in central nervous system is suspected to be related with myelination process by oligodendrocytes. Carbonic anhydrase-II[CA-II], transfe-rrin, and ferritin are known to be present at oligodendrocytes and suspected to play a role in iron metabolism of central nervous system. In this study, demyelination and remyelination of ICR mouse brains were induced using cuprizone, the copper-chelating agent, and immunohistochemical changes of CA-II-, transferrin-, and ferritin-immunoreactive oligodendrocytes at corpus callosum were observed. During demyelination by cuprizone feeding, the numbers of CA-II- and transferrin-immunoreactive oligodendrocytes were decreased. Especially, the decrease ratio of CA-II-positive cells was great. In contrast, the number of ferritin-positive oligodendrocytes was increased during demyelination by cuprizone feeding. Cessation of cuprizone feeding leaded remyelination and the numbers of CA-II-, transferrin-, and ferritin-immunoreactive oligodendrocytes were returned to normal level. In conclusion, the derangement of iron metabolism in oligodendrocytes may be related to demyelination mechanism of central nervous system, and the CA-II is suspected to have an important role in iron metabolism of oligodenrocytes in relation to demyelination and remyelination induced with cuprizone.
Animals
;
Brain
;
Carbon*
;
Central Nervous System
;
Corpus Callosum
;
Cuprizone*
;
Demyelinating Diseases
;
Ferritins
;
Iron
;
Iron-Binding Proteins*
;
Metabolism
;
Mice*
;
Mice, Inbred ICR
;
Myelin Sheath
;
Oligodendroglia
;
Transferrin