1.A Case of Acanthosis Nigricans Induced by Growth Hormone Therapy.
Chan Ho NA ; Sang Ho YOUN ; Min Sung KIM ; Bong Seok SHIN
Korean Journal of Dermatology 2016;54(3):222-223
No abstract available.
Acanthosis Nigricans*
;
Growth Hormone*
2.A case of Arnold-Chiari malformation.
Jong Ho KIM ; Byeong Seog KIM ; Mi Na LEE ; Doo Jin LEE ; Sung Ho LEE
Yeungnam University Journal of Medicine 1992;9(1):203-209
The Arnold-Chiari malformation (ACM) is an anomaly of the hindbrain consisting of two components: a variable displacement of a tongue of tissue derived from the inferior cerebellar vermis in the upper cervical canal and a similar caudal dislocation of the medulla and fourth ventricle. Hydrocephalus and meningomyelocele are another abnormalities that associated frequently. We present a case of Arnold-Chiari malformation with hydrocephalus and meningomyeolcele and a brief review of the literatures was added.
Arnold-Chiari Malformation*
;
Cerebellar Vermis
;
Dislocations
;
Fourth Ventricle
;
Hydrocephalus
;
Meningomyelocele
;
Rhombencephalon
;
Tongue
3.Paradoxical Responses to Oxybutynin Treatment in Localized Hyperhidrosis: Case Report
Min Sung KIM ; In Ho BAE ; Hoon CHOI ; Chan Ho NA ; Bong Seok SHIN
Korean Journal of Dermatology 2019;57(9):558-559
No abstract available.
Hyperhidrosis
4.Two Cases of Malignant Mixed Mullerian Tumor (MMMT) of the Ovary.
Ho Suk SAW ; In Ho KIM ; Jung Ah NA ; Mi Jeong LEE ; Soon Gyu KIM ; Jae Kwan LEE ; Yong Kyun PARK
Korean Journal of Gynecologic Oncology and Colposcopy 1999;10(4):401-405
Malignant Mixed Mullerian tumors(MMMTs) are unusual neoplasms occumng mostly in the uterus and, ralely, they arise in the ovary. The clinical features of malignant mixed mullerian tumor of the ovary are similiar to other ovarian malignancies. The clinical course is rapidly progressive and fatal. The optimal treatment modalities has remained elusive. The most reliable prognostic criterion is the initial tumor stage and the overall survival was poor. We experienced two cases of malignant mixed miillerian tumor of the ovary, so we report these cases with a brief review of the concerned literatures.
Female
;
Ovary*
;
Respiratory Sounds
;
Uterus
5.Hereditary Optic Atrophy, Neural Deafness, and Peripheral Neuropathy.
Geun Ho LEE ; Duk Lyul NA ; Seong Ho PARK
Journal of the Korean Neurological Association 1993;11(3):451-458
The triad of bilateral optic atrophy, hearing deficit, peripheral neuropathy is knoun to be a rare disorder. The authors experienced eight patients in three generations of the same family with this triad of deficits. The disorder developed since their childhood and the course was slowly progressive. Nerve conduction study suggested peripheral neuropathy and sural nerve biopsy was compatible with demyelinating neuropathy, as there were reduction of myelinated nerve fibers in number and focal onion-bulb formation. The mode of inheritance of the family seems to be autosomal dominant, with relatively high penetrance. In many respects, the disorder resembles the cases reported by Sylvester(1958) and Iwashita et al.(1970). But still we do not know the exact etiology of this disorder.
Biopsy
;
Deafness*
;
Family Characteristics
;
Hearing
;
Humans
;
Nerve Fibers, Myelinated
;
Neural Conduction
;
Optic Atrophies, Hereditary*
;
Optic Atrophy
;
Penetrance
;
Peripheral Nervous System Diseases*
;
Sural Nerve
;
Wills
6.Chronic-Binge Ethanol Drinking Exacerbates Liver Damage through Oxidative/Nitrosative Stress.
Korean Journal of Legal Medicine 2011;35(1):22-26
Chronic binge alcohol drinking is a major cause of liver disease including steatosis, chronic hepatitis, and liver cirrhosis. The purpose of this study is to examine the change of oxidative/nitrosative stress in the chronic-binge ethanol model. Using wildtype (WT) mice, we show that chronic binge alcohol drinking develops steatosis and apoptotic cells. Furthermore, the activities of anti-oxidant and mitochondrial enzymes including catalase (CAT), superoxide dismutase 1 (SOD1) and glutathione peroxidase (GPx) were decreased in chronic binge alcohol-treated mice. Protein nitration was also increased in a chronic-binge group compared to pair-fed control counterpart. These findings suggest that chronic binge alcohol drinking plays a critical role in hepatic injury through oxidative/nitrosative stress.
Alcohol Drinking
;
Animals
;
Catalase
;
Drinking
;
Ethanol
;
Glutathione Peroxidase
;
Hepatitis, Chronic
;
Liver
;
Liver Cirrhosis
;
Liver Diseases
;
Mice
;
Oxidative Stress
;
Superoxide Dismutase
7.Bullous Pilomatricoma Misdiagnosed as Neurofibroma.
Min Sung KIM ; Dong Jin KIM ; Chan Ho NA ; Bong Seok SHIN
Korean Journal of Dermatology 2016;54(9):753-754
No abstract available.
Neurofibroma*
;
Pilomatrixoma*
8.Mean Corpuscular volume in alcoholics.
Seog Woon KWON ; Seong Ho PARK ; Duk Lyul NA ; Sang Woon CHOI ; Han Ik CHO
Korean Journal of Clinical Pathology 1992;12(3):299-303
No abstract available.
Alcoholics*
;
Erythrocyte Indices*
;
Humans
9.The Effect of Freezing on Acute Damaged Endothelium in Rat Femoral Vein.
Min Wha NA ; Heung Sik PARK ; Chin Ho YOON ; Han Joong KIM
Journal of the Korean Society of Plastic and Reconstructive Surgeons 1999;26(5):1007-1013
In the case of crush injury, the failure rate of replantation of free tissue transfer is high. Recently, the freezing of intact and repaired microarteries has been known to relieve spasm without inducing thrombosis in vivo. Therefore, the author thought that the vascular freezing of crushed vein showing only unrecognized endothelial damage after adequate debridement of a damaged vessel can also relieve spasm without inducing thrombosis and improve the patency rate of microvascular anastomosis. In this study, the process of vascular freezing was investigated in veins with acutely damaged endothelium using ethly chloride in a rat model. Two experiments were performed in 30 Sprague-Dawley rats, weighing about 250 gm. In the first experiment, a new crush model was established on the femoral vein of the rats. The degree of vessel injury was evaluated as crush energy. The proper crush energy was determined only by the endothelial damage without inducing thrombosis(0.037 J). In the second experiment, femoral veins were crushed with the energy of 0.037 J on the left side and then frozen after inflicted crush injury with the same energy on the right side. The gross and pathologic findings and patency rates were observed at postoperative day 2, 10 and 30. Patency in both the crushed and crush-freezing group was 100%. Pathlolgic findings in the crush-freezing group were more severe loss of the intima and most parts of the media, as well as cellular depopulation of the media when compared to the crushed group. Microthrombi adherent to the wall were demonstrated in several crush-freezing specimens, but the crush-freezing group showed relief of crush-induced vasopasm and endothelial regeneration. In conclusion, the freezing of microveins with acute endothelial damage relieves spasm without inducing thrombosis. Therefore, this study presents the posslbility of clinical application of vascular freezing in a case of crush injury requiring microvascualr anastomosis.
Animals
;
Debridement
;
Endothelium*
;
Femoral Vein*
;
Freezing*
;
Models, Animal
;
Rats*
;
Rats, Sprague-Dawley
;
Regeneration
;
Replantation
;
Spasm
;
Thrombosis
;
Veins
10.Effect of the Isolation Method of Mouse Inner Cell Mass, Types of Feeder Cells and Treatment Time of Mitomycin C on the Formation Rate of ICM Colony.
Ho Jin JANG ; Kyung Rae KO ; Mi Kyung KIM ; Yong Jin NA ; Kyu Sup LEE
Korean Journal of Fertility and Sterility 2006;33(4):265-272
OBJECTIVE: This study was carried out to evaluate the effect of the isolation methods of inner cell mass from mouse blastocyst, types of feeder cells and treatment time of mitomycin C on the formation rate of ICM colony. METHODS: The inner cells were isolated by conventional immunosurgery, partial trophoblast dissection with syringe needles and whole blastocyst co-culture method. Commercially available STO and primary cultured mouse embryonic fibroblast (pMEF) feeder cells were used, and mitomycin C was treated for 1, 2 or 3 hours, respectively. The formation rate of ICM colony was observed after isolation of ICM and culture of ICM on the feeder cells for 7 days. RESULT: The ICM colony formation rate on STO were significantly higher in partial trophoblast dissection group (58%) than that in immunosurgery (12%) or whole blastocyst culture (16%) group (p<0.05). The formation rate on pMEF feeder layer was higher in partial trophoblast dissection (88%) and whole blastocyst culture (82%) group than that in immunosurgery (16%) group (p<0.05). When mitomycin C treated to pMEF for 2 hours, the formation rate of 88% was significantly higher than those of other conditions. CONCLUSIONS: Above results showed that the efficient isolation method of ICM from blastocyst was the partial trophoblast dissection and the appropriate treatment time of mitomycin C was 2 hours. However, the subculture of ICM colony and characterization of stem cells should be carried out to confirm the efficacy of the partial trophoblast dissection method.
Animals
;
Blastocyst
;
Coculture Techniques
;
Feeder Cells*
;
Fibroblasts
;
Mice*
;
Mitomycin*
;
Needles
;
Stem Cells
;
Syringes
;
Trophoblasts