Vertebroplasty and kyphoplasty are well-known, useful techniques for the treatment of painful vertebral compression fractures. Although the risk associated with these procedures is low, serious complications can occur. Of these complications, infection is even rarer, however, when it does occur, it is difficult to manage and can become life-threatening. We describe here a case of infectious spondylitis with epidural inflammation that occurred after performing kyphoplasty in a patient who had a thoracic vertebra compression fracture. We reviewed other case and literatures. Extreme asepsis of the operating theater, screening and treatment for systemic infection prior to the procedure, as well as the use of appropriate antibiotic prophylaxis are strongly recommended when conducting kyphoplasty to prevent infection.
Antibiotic Prophylaxis ; Asepsis ; Fractures, Compression ; Humans ; Inflammation ; Kyphoplasty* ; Mass Screening ; Spine ; Spondylitis* ; Vertebroplasty

BACKGROUND: Wound healing process is a tissue response to trauma which leads to tissue repair through complex biological stages. Sevoflurane is a widely used inhalation anesthetic for surgery, but there has been no study about its effect on wound healing process. This study was undertaken to evaluate the effect of sevoflurane on wound healing process. METHODS: Male Sprague-Dawley rats (200-300 g) were used. Two circular full-thickness skin defects of 8 mm in diameter were made on dorsum of rats. After wound formation, the animals were divided into 4 groups: 1, 2, 4, 8 hr exposure to sevoflurane, respectively. Wound sizes and regional blood flow around the wounds were measured. The expression of basic fibroblast growth factor (bFGF), transforming growth factor beta1 (TGFbeta1), collagen 1, and collagen 3 mRNA were detected 7 days after wound formation by real-time reverse transcriptase-polymerase chain reaction (RT-PCR). RESULTS: Wound size was significantly increased in 8 hr group at 3 and 7 days after wound formation. Regional blood flow was significantly decreased in 4 hr and 8 hr groups at 3 days after wound formation. The bFGF, collagen 1 and 3 mRNA expressions were significantly decreased in 8 hr exposure group. CONCLUSIONS: These results suggest that sevoflurane exposure influences the regional blood flow, wound size, expression of bFGF, and production of collagen 1 and 3 during the wound healing process.
Animals ; Collagen ; Fibroblast Growth Factor 2 ; Humans ; Inhalation ; Male ; Methyl Ethers ; Rats ; Rats, Sprague-Dawley ; Regional Blood Flow ; RNA, Messenger ; Skin ; Transforming Growth Factor beta1 ; Wound Healing

The objective of this study was to provide information regarding trends of rice consumption of Korean adults based on different meal types. Respondent reports 24-hour recall data from the Korean National Health and Nutrition Examination Survey were used to assess daily rice consumption and intake ratios of rice for different meal types and places of preparation. Rice intake had gradually decreased from 224.6 g in 1998 to 190 g in 2001 and to 179.4 g in 2005. The rice consumption of Korean adults decreased every year in all ages for all places of meal preparation in 2001 and 2005 compare to 1998. Analysis for each meal type showed that rice intake at breakfast had not considerably changed, but rice intake had decreased at lunch and dinner. While the rice consumption ratio at lunch and dinner decreased, it also decreased or did not change at snack times except for the 19-29 age groups. All the age groups revealed comparable change in the analysis for meal types. There was some diversity between all age divisions in daily rice intake depending on place of meal preparation. The rice consumption by place of meal preparation was generally highest at home, lowest at other places, but it decreased in all places. The rice consumption at home was highest in the over 50 age group, lowest in the 20-30 age group. These changes seem to be related to food intake patterns of rice and substitutional foods in the diets and development regarding socio-economic status. So the need for further study on differences in rice intake based on socioeconomic levels and age group are indicated.
Adult ; Breakfast ; Surveys and Questionnaires ; Diet ; Eating ; Humans ; Hypogonadism ; Korea ; Lunch ; Meals ; Mitochondrial Diseases ; Nutrition Surveys ; Ophthalmoplegia ; Snacks

No abstract available.
Ciguatoxins ; Eating* ; Intestines* ; Marine Toxins ; Neurologic Manifestations* ; Quadriplegia

PURPOSE: To analyze functional and radiological results after revision TKA using stemmed prosthesis in patients with severe bone defects. MATERIAL AND METHODS: From January 1990 to April 1997, 77 revision TKAs were performed in 67 patients by one surgeon. Fluted diaphyseal intramedullary stems were used in 31 cases with severe bone defects. Metal wedges, augments and bone grafts were used to fill osseous defects when necessary. The average interval between the index arthroplasties and the revision was 6 years and 2 months. The average duration of follow-up was 3 years and 1 month. The causes of revision TKAs included wear in 20 joints, infection in 5, aseptic loosening in 3, ankylosis in 2 and breakage of tibial component in one. RESULTS: The average preoperative knee score, according to the rating scale of The Hospital for Special Surgery, was 63 points and improved to 90 points postoperatively. The average preoperative range of motion was 95 degrees and improved to 125 degrees postoperatively. Radiologically, two cases showed radiolucencies without progression at the interface between bone and cement. At the uncemented stem-to-bone interface, thin radiopaque line developed near the metal in 14 cases. All cases showed no subsidence of components or changes in alignment. CONCLUSION: This technique using a stemmed prosthesis was effective for revision total knee arthroplasty in patients with severe bone defect and instability.
Ankylosis ; Arthroplasty ; Follow-Up Studies ; Humans ; Joints ; Knee ; Prostheses and Implants* ; Range of Motion, Articular ; Transplants

OBJECTIVE: The purpose of this retrospective study is to identify and to discuss the clinical relevance of prognostic factors and survival rate in patients with epithelial ovarian cancer treated with combination chemotherapy. METHODS: A total of 98 histologically verified patients with epithelial ovarian cancer who were treated at Dong-A Medical Center between 1997 and 2002 were used for analysis. The 30 patients having borderline tumor were excluded. Kaplan-Meier survival curves were computed and tested statistically by the log rank test. A multivariable Cox proportional hazard model was applied to access the prognostic significance of the different covariates. RESULTS: The median age of the patients with epithelial ovarian cancer was 46.6 years and FIGO stage distribution was 38.2% for stage I, 5.9% for stage II, 44.1% for stage III, 11.8% for stage IV. The histopathologic type distribution were serous type (45.6%), mucinous type (36.8%), endometriod type (8.8%), clear cell type (7.4%), mixed type (1.4%). Residual tumor volume size of less than 1 cm or 1 cm was identified in 50 patients (73.5%) and more than 1 cm in 18 patients (26.5%) after primary cytoreductive surgery. The overall 5-year survival rate was 55.7%. According to univariate analysis, FIGO stage (p<0.0001), residual volume (p<0.0001), ascitic fluid volume (p=0.0001), menopause (p=0.0021), CA125 (p=0.0058), tumor size (p=0.0099), age (p=0.0113) were significant prognostic factors affecting survival. However, multivariate analysis in this study demonstrated that FIGO stage (p=0.011), residual tumor volume (p=0.026), ascitic fluid volume (p=0.031) were found to be the most significant independent prognostic factors. CONCLUSION: In this retrospective study, the overall 5-year survival rate of patients with epithelial ovarian cancer treated with combination chemotherapy was 55.7% and 5-year survival rate of stage I/II was 95.8%, stage III 28.4%, stage IV 0%. The overall survival of stage I/II were 90 months, stage III 39 months, stage IV 17 months. In multiple analysis, FIGO stage, residual volume, ascitic fluid volume were identified as three most significant independent prognostic factors.
Ascitic Fluid ; Drug Therapy, Combination* ; Female ; Humans ; Kaplan-Meier Estimate ; Menopause ; Mucins ; Multivariate Analysis ; Neoplasm, Residual ; Ovarian Neoplasms* ; Proportional Hazards Models ; Residual Volume ; Retrospective Studies ; Survival Rate

We report a 48-year-old man with laryngeal cancer who received a massive cisplatin toxic overdose without intravenous prehydration through an error in prescription. He received 400 mg/m2 of cisplatin over a 4-day period. On day 4, he exhibited a broad range of cisplatin toxicities and emergency plasma exchange was started. From day 5 through 19, he underwent 9 cycles of plasma exchange and his plasma cisplatin concentration decreased from 2,470 ng/ml to 216 ng/ml. He completely recovered without any sequelae. No previous reports exist in the English literature of survival without complication after the administration of such a high cisplatin dosage without prehydration.
Antineoplastic Agents/*poisoning ; Case Report ; Cisplatin/*poisoning ; Human ; Male ; Middle Age ; Overdose/therapy ; *Plasma Exchange

Monoamniotic twin pregnancies are relatively rare, but perinatal mortality is high about 30-70%. The major cause of fetal death is cord accident, congenital anomalies, twin-twin transfusion syndrome, and intrauterine growth restriction. Especially cord entanglement occurs; perinatal mortality is about 50%. So the active management of monoamniotic twins to reduce the complication of cord entanglement is important. This is a case of monoamniotic twin pregnancy with cord entanglement and both fetuses survival by elective cesarean section at 32+4 weeks after medical amnioreduction and intensive fetal surveillance.
Cesarean Section ; Female ; Fetal Death ; Fetus ; Humans ; Perinatal Mortality ; Pregnancy ; Pregnancy, Twin

Hyperreactio luteinalis rarely occurs in normal single pregnancy. About 50 such cases have been published. It is usually occurs in trophoblastic disease. This case is a huge hyperreactio luteinalis that detected in gestational age 16 weeks. The patient delivered a normal female infant at 41th week of gestation without any mass related problems. The hyperreactio luteinalis was a benign condition in itself with normal spontaneous remission in two months after delivery. Also the level of elevated human chorionic gonadotropin became normal. The conservative management was appropriated. This case is noteworthy because it resulted in spontaneous regression without surgical intervention and conserved ovarian tissue.
Chorionic Gonadotropin ; Female ; Gestational Age ; Humans ; Infant ; Pregnancy* ; Remission, Spontaneous ; Trophoblasts

Premature ovarian failure (POF) is defined as the complete cessation of menses less than 40 years of age. The criteria are more than four months of amenorrhea, with serum follicle stimulating hormone value of >40 mIU/mL and the frequency of POF is about 1% of all women. Although the etiologies of POF remain unknown, suggested factors are genetic, autoimmune, chemotherapy and environmental toxicants. The cytogenetic abnormalities predominantly concern the X chromosome, including Turner syndrome, Fragile X syndrome and deletion or translocation of X chromosome. We report a case of premature ovarian failure with the following karyotype: 46,X,der(X), t(X;11)(q28;p13).
Amenorrhea ; Chromosome Aberrations ; Drug Therapy ; Female ; Follicle Stimulating Hormone ; Fragile X Syndrome ; Humans ; Karyotype ; Primary Ovarian Insufficiency* ; Turner Syndrome ; X Chromosome*