1.Biochemical and Molecular Changes in Response to Environmental Hormones.
Journal of Korean Society of Endocrinology 2000;15(2):150-157
No Abstract Available.
2.The Effect of Relaxation Technique on Postoperatative Discomfort of the Patients with Lumbosacral back pain.
Journal of Korean Academy of Adult Nursing 1997;9(1):22-32
One of the important activities nursing is the alleviating of discomfort including pain as providing comfort to patient. Postoperativediscom has been underestimated because it is only a part of postoperative physiological process and disappear in time. The study was designed to investigate the effect of relaxation technique on postoperative discomfort of patients with lumbosacral back pain. A total of 40 patients were selected as a subject from August 12th to October 10th 1995 who had been hospitalized at NS and OS nursing units in K medical center. Of them twenty were in the experimental group and the remaining twenty were in the control group in convenience sampling. The tools for study were Relaxation technique, designed to use postoperative setting adequately by Park, and Postoperative Discomfort Scale. The data were analyzed by use of t-test an x2 test. The study was concluded as follows : The main hypothesis, that "the experimental group who used relaxation technique will express a lesser score of postoperative discomfort than the control group who did not use relaxation technique" is divided into seven sub-hypotheses. Hypothesis 1, that "the experimental group will express less postoperative pain than the control group"was supported(t=-7.52, p=0.000). Hypothesis 2, that "the experimental group will express less postoperative feeling of unpleasantness than the control group"was supported(t=-7.04, p=0.000). Hypothesis 3, that "the experimental group will express less postoperative immobilization discomfort than the control group"was supported(t=-6.66, p=0.000). Hypothesis 4, that "the experimental group will show fewer nonverbal expressions of postoperative distress than the control group"was supported(t=-3.75, p=0.01). Hypothesis 5, that "the experimental group will use analgesic medication less frequently than the control group" was supported(t=-4.15, p=0.000). Hypothesis 6, that "the experimental group will have less change in vital sings between the pre and postoperative periods than control group"was supported only for respiratory rate(t=-4.06, p=0.000). Hypothesis 7. that "the experimental group will express less postoperative voiding difficulty than the control group"was not supported(t=0.06, p=0.951). As a result, this study showed that relaxation technique has the effect to postoperative discomfort of the patients with lumbosacral back pain, so the researcher thought it is enable for nurses to help patients undergoing postoperative discomfort.
Back Pain*
;
Humans
;
Immobilization
;
Nursing
;
Pain, Postoperative
;
Physiological Processes
;
Postoperative Period
;
Relaxation*
3.A case of ruptured interstitial pregnancy with 19 weeks gestation.
Do Yung CHOI ; Mi Kyung KIM ; Hyang Mi LEE ; Hye Mi LEE ; Sam Soo HO
Korean Journal of Obstetrics and Gynecology 1993;36(1):106-115
No abstract available.
Pregnancy*
5.Growth outcome in congenital hypothyroidism.
Mi Jung PARK ; Ho Seong KIM ; Duk Hi KIM
Journal of the Korean Pediatric Society 1993;36(5):713-720
Congenital hypothyroidism is one of the most common endocrine disease in childhood and it causes not only mental retardation but also growth retardation. There were many papers about evaluation of developmental outcome in congenital hypothyroidism. The aim of this study was to evaluate growth outcome in congenital hypothyroidism. We evaluated 65 patients with congenital hypothyroidism diagnosed at Yonsei University College of Medicine. The results were summerized as follows; 1) The Male to female ratio was 1:1.4 2) Among the 65 patients, under 1 year of age with 16 cases (24.6%), 1~4 years with 19 cases (29.2%), 5~10 years with 22 cases (33.8%), above 10 years with 8 cases (12.3%). 3) Among the 65 patients, 30 cases (46%) had ectopic thyroid, 18 cases (28%) had dyshormonogeneses, 10 cases (15%) had hypoplasia and 7 cases (11%) had aplasia. 4) At the initial diagnosis, all the patients showed decreased T3, T4 and increased TSH level. 5) Before treatment, bone age and height age were delayed but they were normalized after treatment. 6) There was correlation between age of initial treatment and current height percentile. 7) There was significant correlation between initial T3 level and height age delay. 8) In the 4 cases who were diagnosed and treated before the age of 4, final adult height would be achieved within normal range. In conclusion, delayed growth due to congenital hypothyroidism would be prevented by early diagnosis and treatment. Therefore, the recognition of the importance of early diagnosis and treatment is emphasized.
Adult
;
Congenital Hypothyroidism*
;
Diagnosis
;
Early Diagnosis
;
Endocrine System Diseases
;
Female
;
Humans
;
Intellectual Disability
;
Male
;
Reference Values
;
Thyroid Dysgenesis
6.Sex Hormone Binding Globulin Levels in Children with Insulin Dependent Diabetes Mellitus.
Duk Hi KIM ; Mi Jung PARK ; Ho Sung KIM
Journal of the Korean Pediatric Society 1995;38(7):963-969
No abstract available.
Child*
;
Diabetes Mellitus*
;
Humans
;
Insulin*
;
Sex Hormone-Binding Globulin*
7.Clinical Observation of Transient Idiopathic Hypocale=cemia.
Mi Jung PARK ; Duk Hi KIM ; Ho Seong KIM
Journal of the Korean Pediatric Society 1995;38(9):1193-1200
No abstract available.
8.A case of primary hyperparathyroidsm in infancy.
Mi Jung PARK ; Ho Seong KIM ; Duk Hi KIM
Journal of the Korean Pediatric Society 1992;35(7):1008-1013
No abstract available.
Hyperparathyroidism, Primary
9.Hepatic Microabscess with Ascending Cholangitis Complicated by Endoscopic Retrograde Cholangiopancreatogram (ERCP): A Case Report.
Mi Young KIM ; Moon Gyu LEE ; Yong Ho AUH
Journal of the Korean Radiological Society 1994;31(1):131-133
Complicated hepatic microabscess secondary to ascending cholangitis following ERCP (Endoscopic retrograde cholangiopancreatogram) is rare, and needs to be differentiated from other microabscesses, metastasis or Caroli's disease. We experienced a case of hepatic microabscess associated with septic cholangitis following ERCP. Cholangiogram showed multiple sac-like abscess pockets with characteristic biliary communication, and CT scan revealed multiple low attenuated lesions. At the resolving stage of chotangitic microabscess, CT scan showed partial rim enhancement of the abscesses and disproportional dilatation of intrahepatic ducts. The residual parenchymal enhancement surrounding the resolved microabscess pockets and dilatated biliary ducts, however, remained even after clinical recovery.
Abscess
;
Caroli Disease
;
Cholangiopancreatography, Endoscopic Retrograde
;
Cholangitis*
;
Dilatation
;
Neoplasm Metastasis
;
Tomography, X-Ray Computed
10.Correlation of Expression of CD44, p53 and bcl-2 Protein, DNA Ploidy Pattern, and Clinicopathologic Prognostic Factors in Invasive Ductal Carcinoma of the Breast.
Mi Ja LEE ; Ho Jong JEON ; Kweon Cheon KIM
Korean Journal of Pathology 1999;33(12):1152-1162
In this study of 64 cases of breast cancer with a clinical follow-up period of more than 5 years, several prognostic factors were evaluated. The purpose of this study was to determine whether any one parameter or group of parameters serves as adequate predictors of tumor behavior and patient's prognosis. Several prognostic factors included clinicopathological variables (patient's age, histologic grade, status of lymph node (LN) metastasis, and tumor size), expression of estrogen receptor (ER), progesterone receptor (PR), p53, bcl-2 and CD44 by immunohistochemistry, and DNA ploidy pattern. The results showed that the expression of ER and PR had a significant inverse correlation with the histologic grade (ER, p=0.05; PR, p<0.05). The expression of p53 protein showed a significant relationship with high histologic grade of tumor (p<0.05). The expression of bcl-2 protein was preferably seen in low histologic grade of tumor (p<0.05) and significantly associated with ER positive or PR positive tumors (ER, p<0.05; PR, p<0.05). This results suggest that bcl-2 protein might play significant roles in ER and PR. The CD44 expression showed a significant relationship with tumor size (p<0.05). The large size and aneuploidy pattern of tumor had a tendency to be associated with shorter patient survival. Cox's multivariate analysis showed that overall survival was affected by LN metastasis because of the shorter survival in patients with LN metastasis. In conclusion, tumor size, DNA ploidy pattern, and LN metastasis were themselves significant predictors of breast cancer survival rate.
Aneuploidy
;
Breast Neoplasms
;
Breast*
;
Carcinoma, Ductal*
;
DNA*
;
Estrogens
;
Follow-Up Studies
;
Humans
;
Immunohistochemistry
;
Lymph Nodes
;
Multivariate Analysis
;
Neoplasm Metastasis
;
Ploidies*
;
Prognosis
;
Receptors, Progesterone
;
Survival Rate