No abstract available.
Humans ; Hyperglycemia* ; Infant, Newborn ; Infant, Premature*

No abstract available.

No abstract available.
Arthroplasty ; Femoral Fractures ; Hip

No abstract available.
Diagnosis* ; Intervertebral Disc* ; Magnetic Resonance Imaging*

No abstract available.
Female ; Fibroma* ; Ovary* ; Teratoma*

No abstract available.
Epidermal Growth Factor* ; Humans ; Ovarian Neoplasms* ; Receptor, Epidermal Growth Factor*

PURPOSE: Osteoporosis is generally regarded as disease of women and there are extensive data about post-menopausal osteopotosis, but there is relatively little information concerning the osteoporosis in aging male. We aimed to determine the relationships between age ,androgen and bone mineral density (BMD) in elderly korean men. MATERIALS AND METHODS: We evaluated the sex hormones and BMD of 82 elderly men between May 1999 and April 2000. Serum free testosterone (FT), total testosterone (TT), DHT, LH, FSH and Prolactin were measured by RIA. BMD at anteroposterior L2-4, femoral neck, ward's triangle, femoral trochanter and femoral shaft were determined by dual-energy X-ray absorptiometry. We defined group I as free testosterone <10ng/dl and group II as 10ng/dl. RESULTS: Serum LH and FSH increased with age. There was a significant decrease in serum FT with age, but T concentrations remained unchanged. There were significant declines with age in BMD at femoral neck, Ward's triangle, femoral trochanter, femoral shaft. Serum FT were significantly correlated to BMD at anteroposterior L2-4, femoral neck, Ward's triangle, femoral trochanter, femoral shaft. After controlling for age, serum FT were significantly correlated to BMD at femoral trochanter, femoral shaft. Mean BMD was significantly lower in group I than group II at anteroposterior L2-4, femoral shaft. CONCLUSIONS: We suggest that FT is a male osteoporotic marker in man older than 50 years and bone mineral density should be considered for diagnosis of male osteoporosis associated with PADAM, especially when FT is lower than 10ng/dl.
Absorptiometry, Photon ; Aged ; Aging* ; Bone Density* ; Diagnosis ; Female ; Femur ; Femur Neck ; Gonadal Steroid Hormones ; Humans ; Male* ; Osteoporosis ; Prolactin ; Testosterone

No abstract available.
Diagnosis* ; Maternal Age*

No abstract available.
Skull*

BACKGROUND: Diabetes mellitus is a heterogeneous group of disorders characterized by high serum glucose levels and by disturbances of carbohydrate and lipid metabolism. There are many cutaneous signs of this common endocrinopathy, such as nercobiosis lipoidica diabeticorum, diabetic bullosis, shin spot, diabetic pruritus, etc. OBJECTIVE: In this study, we investigated whether extracellular matrix gene expression in cultured skin fibroblast is influenced by insulin and Insulin-like growth factor-I(IGF-I). METHOD: Total RNA was isolated from insulin or IGF-I treated human skin fibroblasts. The Northern blot and slot-blot hybridization were then conducted. RESULTS: The mRNA levels of pro α1(I) collagen, pro α1(I11) collagen, fibronectin in insulin and IGF-I treated normal skin fibroblasts increased compared with untreated normal skin fibroblasts. CONCLUSION: Our results show that insulin and IGF-I stimulate collagen formation in normal skin fibroblast at physiological concentrations. Therefore, these demonstrate that insulin can modulate the expression of extracellular matrix gene.
Blood Glucose ; Blotting, Northern ; Collagen ; Diabetes Mellitus ; Extracellular Matrix* ; Fibroblasts* ; Fibronectins ; Gene Expression ; Humans ; Insulin* ; Insulin-Like Growth Factor I ; Lipid Metabolism ; Methods ; Pruritus ; RNA ; RNA, Messenger ; Skin*