No abstract available.
Female ; Mammaplasty*

The gate control theory was proposed by Melzack & Wall in 1965. This theory implies that selective stimulation of cutaneous afferent fibers of large diameter inhibits pain. Transcutaneous electrical stimulation(TNS) is a practical employment of this concept. TNS was used on 14 herpes zoster patients to relieve associated pain. Good effeet was obtained in 13 patients. They experienced relief of their pain for 1-4 hours after 20 minutes of application. TNS has many advantages over analgesic drugs in the control of pain in herpes zoster.
Analgesics ; Employment ; Herpes Zoster* ; Humans

A very rare case of multifocal eosinophilic granuloma without extraskeletal involvement in 35 year-old ma was experienced. The patient was admitted for the painful swelling of the right clavicular region and was treati with curettage and autograft of iliac bone. Five months later newly developed the pain in the trochanteric lesion left femur without fever, and also was confirmed as the same lesion. Both lesions were treated with curettage and iliac bone graft, and were followed by radiotheraphy. According to the pathological study, those lesions were confirmed as the multifocal eosinophilic granuloma.
Autografts ; Curettage ; Eosinophilic Granuloma ; Eosinophils ; Femur ; Fever ; Humans ; Transplants

The purpose of this study was to evaluate the histologic difference that occured after trichloroacetic acid(TCA) chemical peel in an animal model that was pretreated with Tretinoin alone or Tretinoin-based combined pretreatment kit. Eight Hartley white guinea pigs were used in our study. The dorsal skin of the guinea pigs was divided into six equal squares(2x2 cm). Upper two areas of these six were not pretreated, middle two areas were pretreated for 4 weeks with Tretinoin alone and lower two areas were pretreated for 4 weeks with Tretinoin-based combined kit. Each guinea pig underwent chemical peel with 50% TCA. The wounded areas were biopsied at post-peeling 3 weeks and 6 weeks. The histology revealed that those animals pretreated with combined kit healed quicker than the animals pretreated with Tretinoin alone. This study implies that if patients are treated with Tretinoin-based-combined pretreatment kit before undergoing chemical peel, the pretreatment time will be shortened.
Animals ; Guinea Pigs* ; Guinea* ; Humans ; Models, Animal ; Skin ; Tretinoin* ; Wounds and Injuries

No abstract available.
Breast Implants* ; Breast* ; Contracture* ; Pregnancy*

No abstract available.
Autografts* ; Heterografts* ; Transplants*

PURPOSE: The purpose of this study was to develop in vivo dosimetries using both chromosomal aberrations and micronuclei in mice to assess biological effects of radiations. MATERIALS AND METHODS: Five each mice were irradiated with 0, 1, 2, 3, 4, 5, 10 Gy of Cs-137 gamma-rays. We scored numbers of chromosomal aberrations in metaphase spreads and numbers of micronuclei in bone marrow smears under light microscope, and obtained the dose-response relationships. We also examined the relationship between the two dose-response curves. RESULTS: The frequency of both chromosomal aberrations and micronuclei increased with dose, in a linear-quadratic manner. The delta, beta, and alpha coefficients were 0.0176, 0.0324, and 0.0567 for metaphase analysis (r=1.0, p<0.001) and 0.0019, 0.0073, and 0.0506 for micronuclei assay (r=1.0, p<0.001). The frequency of chromosomal aberrations and micronuclei in diffirent radiation doses was significantly correlated (r=0.99, p<0.01). CONCLUSION: In vivo dosimetry using either metaphase analysis or micronucleus assay was feasible in mice. These methods could be useful to evaluate biological effects of radiation.
Animals ; Bone Marrow Cells* ; Bone Marrow* ; Chromosome Aberrations ; Metaphase* ; Mice* ; Micronucleus Tests

No abstract available.
Female ; Mammaplasty*

In the case of crush injury, the failure rate of replantation of free tissue transfer is high. Recently, the freezing of intact and repaired microarteries has been known to relieve spasm without inducing thrombosis in vivo. Therefore, the author thought that the vascular freezing of crushed vein showing only unrecognized endothelial damage after adequate debridement of a damaged vessel can also relieve spasm without inducing thrombosis and improve the patency rate of microvascular anastomosis. In this study, the process of vascular freezing was investigated in veins with acutely damaged endothelium using ethly chloride in a rat model. Two experiments were performed in 30 Sprague-Dawley rats, weighing about 250 gm. In the first experiment, a new crush model was established on the femoral vein of the rats. The degree of vessel injury was evaluated as crush energy. The proper crush energy was determined only by the endothelial damage without inducing thrombosis(0.037 J). In the second experiment, femoral veins were crushed with the energy of 0.037 J on the left side and then frozen after inflicted crush injury with the same energy on the right side. The gross and pathologic findings and patency rates were observed at postoperative day 2, 10 and 30. Patency in both the crushed and crush-freezing group was 100%. Pathlolgic findings in the crush-freezing group were more severe loss of the intima and most parts of the media, as well as cellular depopulation of the media when compared to the crushed group. Microthrombi adherent to the wall were demonstrated in several crush-freezing specimens, but the crush-freezing group showed relief of crush-induced vasopasm and endothelial regeneration. In conclusion, the freezing of microveins with acute endothelial damage relieves spasm without inducing thrombosis. Therefore, this study presents the posslbility of clinical application of vascular freezing in a case of crush injury requiring microvascualr anastomosis.
Animals ; Debridement ; Endothelium* ; Femoral Vein* ; Freezing* ; Models, Animal ; Rats* ; Rats, Sprague-Dawley ; Regeneration ; Replantation ; Spasm ; Thrombosis ; Veins

Tongue-tie is recognized to have adverse influences in sucking and swallowing(infant feeding), growth of jaw, speech, and mechanical movement due to restrictions of tongue mobility. We used CO2-laser(RYJ-II) in frenulotomy of tongue-tie patients with expectations in reducing intraoperative bleeding, postoperative pain and edema. We operated 32cases of the patient group utilizing CO2-laser(RYJ-II) in frenulotomy, 20 cases of the patient group using classic frenulotomy method with scalpel. We compared following variables in two groups: intraoperative bleeding, operation time and postoperative pain and edema. Frenulotomy using CO2-laser(RYJ-II) resulted in reduction in bleeding, postoperative pain and postoperative edema, while reduction in operation time and wound healing time were not confirmed in this study. Authors suggest the ideal suitability of CO2-laser(RYJ-II) in frenulotomy of tongue-tie patients with a brief review of literature.
Edema ; Hemorrhage ; Humans ; Jaw ; Pain, Postoperative ; Tongue ; Wound Healing