1.Ultrastructural changes in the cardiac myocyte and the extracellular space in different duration of ischemia.
Ho Dirk KIM ; Bong Jin RAH ; Choong Hyun CHANG
Korean Journal of Anatomy 1992;25(1):91-103
No abstract available.
Extracellular Space*
;
Ischemia*
;
Myocytes, Cardiac*
2.A Clinical Study on 16 Cases of Myotonic Dystrophy.
Seung Bong HONG ; Ho Jin MYUNG ; Sung Ho PARK
Journal of the Korean Neurological Association 1985;3(2):254-266
Myotonic dystrophy is a familial multisystem disorder transmitted by autosomal dominant pattern, which is the commonest of adult-onset muscular dystrophies. We analyzed clinically 16 patients of myotonic dystrophy who had admitted at Seoul National University Hospital during past 8.5 years (from Jan. 1977 to July 1985). Sex ratio is 7:1 (male; 14, female;2) and the average age is 29.6 (17-49). Chief complaints, at admission, are relaxation difficulty (88%), extremity weakness (69%), speech disturbance (63%), frontal baldness (38%), and impotence(31%), etc. in that order of frequency. Physical examination showed myotonia and typical myopathic appearnace in all cases. EMG and muscle biopsy revealed typical features of myotonic dystrophy. Associated other abnormalities are EKG abnormality (81%), eye involvement (68.7%), abnormal skull X-ray (46.7%), DM (18.8%), increased serum gonadotropin level (90%), abnormal semen composition (80%), decreased pulmonary function (100%) and mild brain atrophy, etc. Diphenylhydantoin was given and physiotherapy with genetic counselling was performed. Seven of sixteen patients showed slight decrement of myotonia.
Alopecia
;
Atrophy
;
Biopsy
;
Brain
;
Electrocardiography
;
Extremities
;
Gonadotropins
;
Humans
;
Muscular Dystrophies
;
Myotonia
;
Myotonic Dystrophy*
;
Phenytoin
;
Physical Examination
;
Relaxation
;
Semen
;
Seoul
;
Sex Ratio
;
Skull
3.A Clinical Comparison of AcrySof(r) with Hyd rophilic Acrylic IOLs.
Jin Ho SEO ; Ki Bong KIM ; Jeong Bong SEO
Journal of the Korean Ophthalmological Society 2001;42(2):266-271
To evaluate and compare the clinical results of implantation of the AcrySof(r) with Hydrophilic Acrylic IOLs in early postoperative period(to 2 months), we retrospectively analyzed 34patients who had taken clear cornea incision and had been implanted with AcrySof(r)IOL in one eye and Hydrophilic Acrylic IOL in the other eye. There were no stastically significant difference in postoperative best corrected visual acuity, preoperative and postopearative astigmatic changes between AcrySof(r) and Hydrophilic Acrylic IOLs. But, the rates of postoperative capsular fibrosis and contracture of Hydrophilic Acrylic IOL was higher than those of AcrySof(r) IOL as well as postoperative complications. In conclusion, in the degree and rate of after-cataract, AcrySof(r)IOLs are more useful than Hydrophilic Acrylic IOLs. ;therefore, more excellent in long term visual prognosis. Further studies will be needed for the evaluation of clinical safety and efficacy.
Contracture
;
Cornea
;
Fibrosis
;
Postoperative Complications
;
Prognosis
;
Retrospective Studies
;
Visual Acuity
4.Studies on the Development of Lung and Distribution of Elastic and Reticular Fibers during Fetal Period Proper.
Dae Joong KIM ; Ho Dirk KIM ; Bong Jin RAH ; Jin Mo LEE ; Tae Sub SHIM
Korean Journal of Physical Anthropology 1990;3(2):131-144
To investigate the human lung development and the distribution of elastic and reticular fibers during the fetal period proper, lung tissues taken from the periphery of the right lower lobes of Korean fetuses (n=49) of both sex were studied. The fetuses were the prodocts of spontaneous or therapeutic abortions and were found to have no associated lesions or anomalies at autopsy. The fetal age were estimated from crown-rump length or foot length. Paraffin sections, cut at 5-7 µm, were stained with routine hematoxylin and eosin for general structure, acid orcein and a1dehyde fuchsin for elastic fiber, and with Gomori's silver technique for reticular fiber, respectively. The lung development during fetal period proper, could be subdivided into three continuous periods according to the relation between airspaces, surrounding mesenchymal tissue, their structural changes and distribution, i.e., an early stage of the formation of conductive airways (pseudoglandular period, before 16th week of gestation), a middle stage of the development of lung parenchyma and new blood vessels (canalicular period, between 16th and 28th week of gestation), and a late stage of transition of respiratory portion to vascular organ (terminal sac stage, after 28th week of gestation). In places, secondary septa of sac or saccule formed by capillaries, capillary connective tissue, elastic and reticular fuel could be identified by the 33rd week of gestation. Elastic fibers could be noted in pleura, subepithelial areas of bronchioles and the wall of blood vessels in the late stage of pseudoglandular period. By the 28th week of gestation, elastic fibers were seen in the wall of small blood vessels or capillaries in the septal wall among the airspaces. And these fibers were observed in the tip of the secondary septa by the 33rd week of gestation but were not still completely developed in the walls of primary or secondary septa. Reticular fibers were already developed and widely distributed in fetal lung by the 10th week of gestation. These fibers were concentrated particular around the subepithelial area of bronchicoles, the airspaces and the blood vessel wall in the canalicular period. By the late stage of terminal sac period, reticular fibers formed a network along the small blood vessels in the septum of airspaces. These results indicate that primitive alveoli might be formed by the late stage of fetal period proper. The fibrous framework could partially formed by collagenous and reticular fibers during the pseudoglandular period, by addition of elastic fiber to the preformed network, and incompletely still finally by the three kinds of connective tissue fiber.
Abortion, Therapeutic
;
Autopsy
;
Blood Vessels
;
Bronchioles
;
Capillaries
;
Collagen
;
Connective Tissue
;
Crown-Rump Length
;
Elastic Tissue
;
Eosine Yellowish-(YS)
;
Female
;
Fetus
;
Foot
;
Gestational Age
;
Hematoxylin
;
Humans
;
Lung*
;
Paraffin
;
Pleura
;
Pregnancy
;
Reticulin*
;
Rosaniline Dyes
;
Saccule and Utricle
;
Silver
5.Ischemic Preconditioning in Isolated Rabbit Heart : Effect on Left Ventricular Function, Infarct Size, and Protein Kinase C*.
Ho Jun YOO ; Jun Soo PARK ; Hyun KIM ; Un Ho RYOO ; Bong Jin RAH ; Ho Dirk KIM
Korean Circulation Journal 1996;26(2):541-552
BACKGROUND: It has been demonstrated that ischemic preconditioning(IP, repetitive brief period of ischemia and reperfusion) enhances recovery of post-ischemic contractile dysfunction and reduces incidences of reperfusion-arrhythmia and infarct size after a prolonged ischemia. A lot of mechanisms have been proposed, however, controversies still remain. Recent studies suggested that IP could activate protein kinase C(PKC). Therefore, we measured left ventricular function, myocardial creatinin and PKC activities, and infarct size to assess whether IPs cardioprotective effect is related to PKC activation using isolated rabbit hearts. METHODS AND RESULTS: Hearts isolated from New Zealand White rabbits(1.5-2.0kg body weight) were perfused with Tyrode solution by Langendorff technique. After stabilization of baseline hemodynamics, the hearts were subjected to 60-min ischemia followed by 120-min reperfusion with IP(IP group, n=15) or without IP(control group, n=14), IP was induced by 4 cycles of 5-min global ischemia and 5-min reperfusion. Left ventricular function including developed pressure(LVEDP), dp/dt, heart rate(HR), and coronary flow(CF) was measured to determine the recovery of LVEDP, RPP(rate-pressure product, HRXLVEDP) and CF to baseline measurement. Frequency of arrhythmia was counted on reperfusion. Myocardial CK-MB, myocardial cytosolic and membrance PKC were measured and the infarct size was determined by staining with tetrazolium salt and planimetry. Data were analyzed by one-way ANOVA, Tukey's post-hoc test and t-test. There was no significant differences in the recovery of LVEDP, dp/dt, RPP, and CF and frequency of arrhythmia during reperfusion between the control and the IP groups. In comparison with the control groups, however, CK-MB was significantly lowered in the IP group(P < 0.05). Cytosolic PKC was significantly decreased but membrance PKC was increased(p < 0.05). These findings indicate that PKC was translocated and activated by IP. Furthermore infarct size was smaller and limited to the antero-lateral or posterior wall and papillary muscle in the IP group(p < 0.05). CONCLUSION: These results indicate that IP dose not improve post-ischemic contractile dysfunction after a prolonged ischemia of 60 minutes but has an infarct-limiting effect. This cardioprotective effect of IP may be related to PKC activation.
Arrhythmias, Cardiac
;
Cytosol
;
Heart*
;
Hemodynamics
;
Incidence
;
Ischemia
;
Ischemic Preconditioning*
;
New Zealand
;
Papillary Muscles
;
Protein Kinase C
;
Protein Kinases*
;
Reperfusion
;
Ventricular Function, Left*
6.A Case of Palmar Hyperhidrosis Treated with Oxybutynin in Child.
Min Sung KIM ; Dong Jin KIM ; Chan Ho NA ; Bong Seok SHIN
Korean Journal of Dermatology 2015;53(6):494-495
No abstract available.
Child*
;
Humans
;
Hyperhidrosis*
7.A study on the complete retrieval system of the cementation type implant abutment.
The Journal of Korean Academy of Prosthodontics 2004;42(5):597-607
PURPOSE: This study was performed to investigate the retrievability of the cemented crown from the cementation type implant abutment. MATERIAL AND METHOD: The cementation type implant abutments (NEOBIOTECH implant abutment regular, 3 degree taper, 10mm length, 4mm diameter, Ti grade III, machined surface, Hwasung, Kyunggi-do) and cemented crowns were divided into 3 groups, depending on their hole angles formed in the crowns for their retrievability. The abutments and crowns were luted with 4 kinds of cements and separation test using metal wedge was executed with Instron 4465 Universal Testing Machine and the maximum impact force of the modified crown ejector was measured. RESULTS AND CONCLUSION: 1. All of the cementation type implant abutments and cemented crowns were separated with relatively small force by metal wedge. 2. The retrieving force was minimum when the metal wedge was applied perpendicular to the axis of abutment. 3. The force for retrieving crowns from abutments was maximum in resin cement group, and reduced in orders of zinc phosphate cement, glass ionomer cement and zinc oxide eugenol cement. 4. The maximum force obtained by the crown ejector was higher than the retrieval force in ZOE and GI cement and lower than that in ZPC and resin cement. 5. If it has similar conditions clinically, the cemented crowns luted with 2 types of cements (ZOE, GI cement) can be safely retrieved from the cementation type implant abutments by the modified crown ejector.
Axis, Cervical Vertebra
;
Cementation*
;
Crowns
;
Glass Ionomer Cements
;
Resin Cements
;
Zinc Oxide-Eugenol Cement
;
Zinc Phosphate Cement
8.Bullous Pilomatricoma Misdiagnosed as Neurofibroma.
Min Sung KIM ; Dong Jin KIM ; Chan Ho NA ; Bong Seok SHIN
Korean Journal of Dermatology 2016;54(9):753-754
No abstract available.
Neurofibroma*
;
Pilomatrixoma*
9.A Case of Foreign Body in the Bladder.
Nam Kyn LEE ; Young Ho PARK ; Jin KANG ; Dal Bong OH
Korean Journal of Urology 1975;16(2):121-122
A case of foreign body (a piece of wood) in the bladder by penetrating perineal injury was presented in a 13 years old Korean boy and reported with review of literature.
Adolescent
;
Foreign Bodies*
;
Humans
;
Male
;
Urinary Bladder*
10.A case of meconium peritonitis diagnosed before delivery.
Cheol Seong BAE ; Suk Bong KOH ; Kee Jin KWUN ; Yoon Kee PARK ; Sung Ho LEE
Korean Journal of Obstetrics and Gynecology 1993;36(3):415-419
No abstract available.
Meconium*
;
Peritonitis*