2.Human Embryos of Carnegie Stage 17.
Ho YOON ; Hyun KIM ; Hyung Woo PARK
Korean Journal of Anatomy 1997;30(3):235-242
Morphological characteristics of human embryos of Carnegie stage 17 were described. The crown rump length of these embryos were 11.7-13.6mm. These embryos were characterized externally by ventrally directed nasal pits, 6 distinct auricular hillocks, finger rays in the hand plate, digital plate at the lower limb bud, herniation of a part of midgut through umbilical cord, and internally by the partial fusion of ventral and dorsal pancreas, prominent nasal sac which is not open to primitive oral cavity, formation of segmental and some subsegmental bronchial buds, branching of metanephrotic pelvis, crescent-shaped lens cavity, and imminent semicircular ducts.
Crown-Rump Length
;
Embryonic Structures*
;
Fingers
;
Hand
;
Humans*
;
Lower Extremity
;
Mouth
;
Pancreas
;
Pelvis
;
Semicircular Ducts
;
Umbilical Cord
3.A Clinicopathologic Analysis of Pseudomyxoma Peritonei Originated from Mucinous Ovarian Tumors.
Ji Hyun PARK ; Young Ho YANG ; Jae Ho HAN
Korean Journal of Obstetrics and Gynecology 1999;42(8):1808-1814
OBJECTIVE: The aims of this study were to analyze the natural history of patients with pseudomyxoma peritonei originated from mucinous ovarian tumor, evaluate clinical and pathologic variables, and review our experience with available therapeutic modalities. METHODS: Six patients were treated for pseudomyxoma peritonei originating from mucinous ovarian tumor at Severance Hospital between 1990 and 1998. The data were collected retrospectively and all charts were reviewed RESULTS: The mean age at diagnosis was 51 years, and most common symptoms were abdominal distension. Pseudomyxoma peritonei was found in association with five mucinous ovarian tumors of borderline malignancy, and one ovarian mucinous adenoma. All patients underwent surgical staging and cytoreduction, three patients received postoperative adjuvant chemotherapy and, of these, two developed recurrence. With respect to survival, all patients were alive, four were alive and free of disease, two were alive with disease at the end point of study. CONCLUSION: Pseudomyxoma peritonei is commonly associated with borderline mucinous ovarian tumors, and is a frequently relapsing and protracted disease. But aggressive and repeated debulking surgery is recommended for long survival.
Adenoma
;
Chemotherapy, Adjuvant
;
Diagnosis
;
Humans
;
Mucins*
;
Natural History
;
Pseudomyxoma Peritonei*
;
Recurrence
;
Retrospective Studies
4.THE POSTOPERATIVE ANALYSIS OF CLOSED REDUCTED NASAL BONE FRACTURE.
Jang Ho KIM ; Sang Hyun PARK ; Han Ho CHU ; Jin Whan CHO ; Yoo Hyun BANG
Journal of the Korean Society of Plastic and Reconstructive Surgeons 1997;24(6):1343-1351
No abstract available.
Nasal Bone*
5.Utility of Volume Assessment Using Bioelectrical Impedance Analysis in Critically Ill Patients Receiving Continuous Renal Replacement Therapy: A Prospective Observational Study.
Ki Hyun PARK ; Jung ho SHIN ; Jin Ho HWANG ; Su Hyun KIM
Korean Journal of Critical Care Medicine 2017;32(3):256-264
BACKGROUND: Fluid overload prior to continuous renal replacement therapy (CRRT) is an important prognostic factor. Thus, precise evaluation of fluid status is necessary to treat such patients. In this study, we investigated whether fluid assessment using bioelectrical impedance analysis (BIA) can predict outcomes in critically ill patients requiring CRRT. METHODS: A prospective observational study was performed in patients who were admitted to the intensive care unit and who required CRRT. BIA was conducted before CRRT; then, the ratio of extracellular water to total body water (ECW/TBW) was derived to estimate volume status. RESULTS: A total of 31 patients treated with CRRT were included. There were 18 men (58.1%), and the median age was 67 years (interquartile range, 51 to 78 years). Fourteen patients (45.2%) died within 28 days after CRRT initiation. Patients were divided into 16 with ECW/TBW ≥0.41 and 15 with ECW/TBW <0.41. Survival rate within 28 days was different between the two groups (P = 0.044). Cox regression analysis revealed a relationship between ECW/TBW ≥0.41 and 28-day mortality, but it was not statistically significant (hazard ratio, 3.0; 95% confidence interval, 0.9 to 9.8; P = 0.061). Lastly, the area under the curve of ECW/TBW for 28-day mortality was analyzed. The area under the curve of ECW/TBW was 0.73 (95% confidence interval, 0.54 to 0.92), and this was significant (P = 0.037). CONCLUSIONS: Fluid status can be assessed using BIA in critically ill patients requiring CRRT, and BIA can predict mortality. Further large trials are needed to confirm the usefulness of BIA in critically ill patients.
Body Water
;
Critical Illness*
;
Electric Impedance*
;
Humans
;
Intensive Care Units
;
Male
;
Mortality
;
Observational Study*
;
Prospective Studies*
;
Renal Replacement Therapy*
;
Survival Rate
;
Water
6.Minimal Change of Lymphocyte Subsets in 24 Hours-Stored Whole Blood Sample.
Hyun Soo KIM ; Seung Ho LEE ; Myoung Hee PARK
Korean Journal of Clinical Pathology 1997;17(2):331-338
BACKGROUND: In recent years, lymphocyte subset analysis in peripheral blood is widely performed using erythrocytes-lysed whole blood and two color immunofluorescence/flow cytometry method. Use of fresh blood drawn within 6 hours of staining is recommended, and some patients have to revisit the hospital for blood collection. We tested whether 24 hours-refrigerated/stored whose blood can be used for lymphocyte subset analysis. METHODS: Twenty consecutive blood samples from patients (including nine HIV positive patients) collected in EDTA-vacutainer were tested: 1) on the day of sampling using fresh blood kept at room temperature for up to 6 hours until staining (as recommended by the manufacturer) and 2) on the following day using the same tube of blood refrigerated for 24 hours after the first staining. Two colon immunofluorescenc staining was done using Simultest(TM) IMK-Lymphocyte kit (Beckon Dickinson, U.S.A.) and flow cytometric analysis was performed using FACScan and SimulSET(TM) software (Becton Dickinson, U.S.A.). Results of alive kinds of Lymphocyte subsets (CD3+, CDl9+, CD3+CD4+CD3+CD8+, CD3-CDl6+ and/or CD56+) on day 1 and day 2 were compared by pained-t test and Wilcoxon signed rank test. RESULTS: There was no significant change of values for all of the lymphocyte subsets except CD3+CD8+suppressor/cytotoxic (S/C) T cells. There was a slight but statistically significant change in S/C T cells (39.9%-->41.8%: 1.9%, p=0.008) after 24 hours of refrigeration, and this change was observed mainly in HIV-positive patient group. However, there was no significant change in the absolute count of helper/inducer T cells or CD4/CD8 ratio, and the change of S/C T cells in these patients was not considered to be of clinical significance. CONCLUSIONS: The difference in the values of lymphocyte subsets between fresh blood and 24 hours-refrigerated blood was negligible and it is concluded that 24 hours-stored blood samples can be used for lymphocyte subset analysis for clinical purposes.
Colon
;
HIV
;
Humans
;
Lymphocyte Subsets*
;
Lymphocytes*
;
Refrigeration
;
T-Lymphocytes
7.A Case of Congenital Subglottic Stenosis.
Ho Taek KIM ; Pyung Kil KIM ; Ki Hyun PARK
Journal of the Korean Pediatric Society 1988;31(1):119-123
No abstract available.
Laryngostenosis*
8.A STUDY ON THE FACTORS AFFECTING TO TOOTH WEAR.
Hyun Bae PARK ; Tai Ho JIN ; Kyung Soo HAN
The Journal of Korean Academy of Prosthodontics 1999;37(3):328-342
This study was performed to investigate the factors related to tooth wear. For this study, 78 patients with temporomandibular disorders and 76 dental students without any signs and symptoms of temporomandibular disorders were selected as the patients group and as the normal group, respectively. Preferred chewing side, Angle's classification, lateral guidance pattern, head and shoulder posture wee observed clinically. Electromyographic activity of anterior temporalis and masseter muscle were recorded with BioEMG and occlusal status were recorded with T-Scan . Wear facet area of each tooth was measured from working model of upper arch corresponding to the occlusal status from T-Scan, Wear facet area were measured with planimeter in mm2. Total area were divided into incisal, canine, posterior tooth area. Anterior wearfacet area was incisor area plus canine area, and unilateral area was anterior area plus posterior area. The data collected were analyzed by SAS statistical program and the results of this study were as follows: 1. There was no significant difference between the two groups in total werafacet area, and male subjects showed tendency to have larger area in the normal group but female subjects showed tendency vice versa. 2. There was no significant difference related to preferred chewing side and Angle's classification, however, some difference was observed by lateral guidance pattern. Anterior wear facet area in subjects of canine guidance was the largest in the three subgroups. 3. Subjects with head tilting to right side had larger posterior and total area, and subjects with higher shoulder in right side had larger canine and anterior area than any other subgrous. 4. Electromyographic activity of masseter muscle was more correlated with wear facet area than anterior temporalis muscle, and tooth contact number and force were significantly correlated with wear facet area, but the most important factor affecting tooth attrition was age.
Dental Occlusion
;
Female
;
Head
;
Humans
;
Incisor
;
Male
;
Malocclusion
;
Masseter Muscle
;
Mastication
;
Posture
;
Shoulder
;
Students, Dental
;
Temporomandibular Joint Disorders
;
Tooth Attrition
;
Tooth Wear*
;
Tooth*
9.A case of organic hallucinosis with left temporal lobe atrophy.
Se Hyun PARK ; Young Ho LEE ; Young Cho CHUNG
Journal of Korean Neuropsychiatric Association 1993;32(2):273-278
No abstract available.
Atrophy*
;
Temporal Lobe*
10.The Evaluation of SCC (squamous cell carcinoma antigen) Level as a Tumor Marker in Patient with Squamous Cell Carcinoma of the Cervix.
Sung Yong PARK ; Sang Jin KIM ; Hyun Ho KIM
Korean Journal of Gynecologic Oncology and Colposcopy 1999;10(4):324-330
This study was performed to evaluate the clinical significance of SCC as a tumor marker in patient with squamous cell carcinoma of the cervix. We measured the serum levels of SCC by radioimmunoassay in patient with invasive squamous cell carcinoma of cervix to determine the prognostic value, correlation with the presence of lymph node metastasis, response to treatment, and those value in the early detection of recurrence after treatment. The result was: 1) In 117 of 174 patients with cervical cancer, the pretreatment positive rate of SCC was 47.0%(57/117). In each stage, the stage Ia was 25.0%, Ib 26.3%, IIa 56.0%, 62.6%, III 57.1%, IV 100%, and the recurrent case was 37.5%. 2) In 79 of 174 patients with cervical cancer, the pretreatment positive rate of SCC was 44,0%(30/69) in no evidence of malignancy patients, but 60.0%(6/10) in recurrent or permanent patients(p>0.05), 3) In 133 of 174 patients with cervical cancer, the posttreatment positive rate of SCC was 2.6%(3/117) in no evidence of malignancy patients, but 50.0%(8/16) in recurrent or permanent patients(p<0.05). 4) In 48 patients of 174 with cervical cancer who underwent radical hystrectomy, the positive rate of SCC was 71.4%(5/7) in pelvic lymph node positive patients but 19,5%(8/41) in pelvic lymph node negative patients(p<0.05). We concluded that the pretreatment SCC level was not effective as a prognostic value, but well correlated with pelvic lymph node metastasis, and serial measurements of serum levels of SCC provided a reliable clue for early detection of recurrence or progression of disease, so it may be useful for monitoring cervical carcinoma patient.
Carcinoma, Squamous Cell*
;
Cervix Uteri*
;
Female
;
Humans
;
Lymph Nodes
;
Neoplasm Metastasis
;
Radioimmunoassay
;
Recurrence
;
Uterine Cervical Neoplasms