No abstract available.
Fatigue Syndrome, Chronic*

No abstract available.
Fibromyalgia* ; Humans ; Physicians, Primary Care* ; Primary Health Care*

No abstract available.
Fatigue Syndrome, Chronic* ; Humans ; Physicians, Primary Care* ; Primary Health Care*

BACKGROUND: Breast cancer is increasing cause of cancer-related mortality among Korean women. Early detection and treatment are the most important strategy for reducing breast cancer mortality. Despite of its importance as a early detection method, a low percentage of women practice breast self-examination(BSE) regularly. The aim of this study was to describe the effectiveness of patient education on performing BSE regularly and to identify predisposing factors associated with these activities. METHODS: Sixty-six women who did not have experience in BSE in the past were randomly assigned to the experimental group and the control group. We taught BSE knowledge and skill about BSE using breast models and audiovisual equipment for experimental group in patient education class. Women in control group, however, were simply educated by their physician about BSE knowledge and skill with only educational booklet during their outpatient visits. We observed the difference in regular BSE performance proportion between two groups 6, 12 months later and analyzed the predisposing factors affecting on the education effect. Direct and telephone interview methods were used to gather the information. Data were analyzed with t-test, x2analysis and logistic regression using SAS 6.10, EGRET program. RESULTS: There were no differences in sociodemographic characteristics between study groups. They were followed for 12 months. At follow-up after 6 months 44.1% of women performed BSE regularly among experimental group and 18.8% of women did it among control group(OR=3.4, 95% Cl 1.1-10.4, p<0.05). At follow-up after 12 months proportion of women performed BSE regularly in experimental group(28.6%) was slightly higher than that of control group(22.2%), but that difference was not statistically significant. The prevalence of performing BSE regularly was higher among women who had experience in periodic health examination(OR =6.0, 95% Cl 1.9-18.8, p<0.01), who had experience in mammography(OR =4.0, 95% Cl 1.0-15.6, p<0.05). And the prevalence of performing BSE regularly also was higher among women who were older than 40 years old, married, had experience in cervical Pap. smear, had knowledge about BSE before education, have done exercise regularly, had less number of health risk factors, but without statistical significance. CONCLUSIONS: These results showed that of effectiveness of patient education on BSE, if we determine the effectiveness of BSE education with regular performance of BSE, is relatively low among Korean women. We could see, however, that if we use breast models for demonstration in addition to usual educational material, the effectiveness of BSE education can be more effective. We also recognized that effectiveness of BSE education will not be continued for long time without any maintenance strategy. There were lots of predisposing factors which could affect the effectiveness of BSE education positively or negatively. So, family physicians who plan BSE patient education at their clinics must consider these factors.
Adult ; Breast Neoplasms ; Breast Self-Examination* ; Breast* ; Causality ; Education* ; Female ; Follow-Up Studies ; Humans ; Interviews as Topic ; Logistic Models ; Mortality ; Outpatients ; Pamphlets ; Patient Education as Topic ; Physicians, Family ; Prevalence ; Risk Factors

No Abstract Available.
Fatigue Syndrome, Chronic* ; Fatigue* ; Prevalence*

BACKGROUND: The positive reactions of carcinoembryonic antigen(CEA) show varying degrees in the tissue of all sweat gland neoplasms by immunohistochemistry. The CEA secreted from sweat glands presents a high value, compared with that of serum. OBJECTIVE: The study was to evaluate the sweat CEA value in relation to serum CEA value by sex, smoking status and blood type in healthy subjects. METHOD: Fifty-two healthy subjects(M : 43, F :9) aged 21-30, participated in the study. 2ml sweat was collected from the face and chest after intense exercises and 3ml blood was collected from their antecubital veins. Roche Core CEA enzyme immunoassay was used for the measurement of sweat and serum CEA. RESULTS: Sweat CEA values were 102.0+4100.5ng/ml in males and 70.6+458.5ng/ml in females, with their mean valueof 96.6+/-94.9ng/ml. Sweat CEA values were 108.3+/-103.5ng/ml in 27 smokers and 83.9+/-84.8ng/ml in 25 nonsmokers(p>0.05, t-test). Sweat CEA values were higher among the males and the smokers. Serum CEA values were 2.5+/-1.7ng/ml in males and 1.6+/-0.8ng/ml in females, with its mean value of 2.4+/-1.6ng/ml. There was no difference between serum values of smokers and nonsmokers. Sweat CEA values were about 40 times higher than those of serum, with no correlation of sweat and serum CEA(correlation coefficient=-0.16, P>0.05). In the blood type study, sweat CEA values were 123.1+/-131.8ng/ml in A type and 66.1+/-55.0ng/ml in B type(P>0.05), whereas serum CEA values were higher in AB type and lower in O type(P<0.05, ANOVA). CONCLUSION: Sweat CEA values are extraordinarily high in contradistinction to serum. Sweat CEA values are not affected by sex, smoking status and blood type. There seems to be no association between CEA values of sweat and serum.
Carcinoembryonic Antigen* ; Exercise ; Female ; Humans ; Immunoenzyme Techniques ; Immunohistochemistry ; Male ; Smoke ; Smoking ; Sweat Gland Neoplasms ; Sweat Glands ; Sweat* ; Thorax ; Veins

BACKGROUND: With the increase of cigarette consumption by women and the young, the incidence of lung cancer is expected to increase during the next three or four decades in Korea. The purpose of this study was to analyze the smoking habits in patients with lung cancer and to identify the gender differences in terms of their susceptibility to cigarette related carcinogens. METHODS: This investigation was a hospital-based case control study, which included the data of 178 case subjects(72 females, 106 males) with lung cancer and 218 control subjects(97 females, 121 males) with diseases unrelated to smoking. The information was obtained through a direct personal interview and a questionnaire related to personal smoking history. RESULTS: The relative frequency of the squamous cell carcinoma was substantially higher in males than in females(61.3% in males, and 29.2% in females), while adenocarcinoma including bronchoalveolar cell carcinoma was higher in females(31.9% in females, 18.9% in males). Keryberg Ilung cancer was of relatively higher frequencies in males and smokers. while Kreyberg IIlung cancer was higher in females and never smokers. The odds ratios(ORs) at each exposure level were consistently higher in females than males. For all cell types, the risk of lung cancer was increased with the quantity of smoked cigarettes, duration of smoking, and depth of inhalation. Odds ratio was distinctly higher in Kreyberg Ilung cancer than in total lung cancer and a steeper gradient of risk with increased smoking was observed in females. CONCLUSION: The ralative risk for lung cancer was consistently higher in females than in males at every level of exposure to cigarette smoke. This is believed to be due to the higher susceptibility of females to tabacco carcinogens, such as gender associated differences of carcinogen activation and/or the elimination of smoking related metabolites.
Adenocarcinoma ; Carcinogens ; Carcinoma, Squamous Cell ; Case-Control Studies ; Female ; Humans ; Incidence ; Inhalation ; Korea ; Lung Neoplasms* ; Lung* ; Male ; Odds Ratio ; Smoke* ; Smoking* ; Tobacco Products

Drowning is a leading cause of accidental deaths worldwide, but its pathological diagnosis remains a challenge for forensic pathologists owing to a lack of pathognomonic findings in drowning deaths and inconclusive autopsy findings caused by postmortem changes. The aim of the present study was to investigate the pathway taken by inhaled drowning medium through the airway after death in a variety of experimental conditions, including underwater pressurization. We used methylene blue dye to monitor the spread of drowning medium to the lungs. Results of theses experiments demonstrated that it is possible for a significant amount of downing medium to enter the airway during immersion after death. Our results suggest that autopsies of immersed bodies and interpretation of these findings should be performed with special care.
Animal Experimentation* ; Animals* ; Autopsy ; Diagnosis ; Drowning* ; Immersion ; Inhalation* ; Lung ; Methylene Blue* ; Postmortem Changes

No abstract available.
Alcoholism* ; Primary Health Care*

BACKGROUND: Patients with locally advanced non-small cell lung cancer are often treated with radiation alone or in combination with chemotherapy. Both modalities have a potentially damaging effect on pulmonary function. In order to examine changes in the cardiopulmonary exercise function of patients with locally advanced non-small cell lung cancer before and after conventional radiotherapy, we conducted a prospective study involving patients with such cancer, that had received radiation therapy. METHODS: Resting pulmonary function test, thoracic radiographic finding and cardiopulmonary exercise test(CPET) were assessed prior to and 4 weeks following radiation therapy in 11 male patients with locally advanced non-small cell lung cancer. Patient with endobronchial mass were excluded. RESULTS: The forces vital capacity(FVC), forced expiratory volume in 1 second(FEV1)and maximal voluntary ventilation(MVV) did not decreased between before and 4 weeks after radiation but the diffusing capacity(DLCO) had decreased by 11% 4 weeks after radiation, which was not statistically significant. No changes in maximal oxygen consumption(VO2max), carbon dioxide production(VCO2), exercise time and work load were attributed to radiation therapy. Follow up cardiopulmonary exercise testing revealed unchanged cardiovascular function, ventilatory function and gas exchange. No difference in cardiopulmonary exercise test performance was observed between pre- and post-radiation. CONCLUSION: Cardiopulmonary exercise function did not decrease within the short-term after the radiation of patients with locally advanced non-small cell lung cancer.
Carbon Dioxide ; Carcinoma, Non-Small-Cell Lung* ; Drug Therapy ; Exercise Test ; Follow-Up Studies ; Forced Expiratory Volume ; Humans ; Lung Neoplasms ; Male ; Oxygen ; Prospective Studies ; Radiotherapy ; Respiratory Function Tests