Community-acquired Pseudomonas aeruginosa bacteremia in children is uncommon but often fatal.Fever,diarrhea,dyspnea or tachypnea are the most common initial symptoms.Ecthyma gangreno-sum is the characteristic skin lesion of Pseudomonas aeruginosa bacteremia.Complicated with shock,respira-tory failure,multiple organs dysfunction and inappropriate initial antimicrobial therapy are the risk factors for mortality.The key to early diagnosis is to obtain blood culture as soon as possible and early recognition of the characteristic skin lesion.For suspected cases,it is advisable to cover for Pseudomonas aeruginosa sepsis with anti-Pseudomonas antibiotics.