1.Malignant fibrous histiocytoma
Mun Gyu LEE ; Seung Ro LEE ; Dai Young KIM
Journal of the Korean Radiological Society 1982;18(1):177-182
Malignant fibrous histiocytoma is a rare malignant tumor of histiocytic origin, arising from either bone, or soft tissue. Six cases of malignant fibrous histiocytoma are presented with emphasis on radiographic features. Five cases are of primary bone origin and one of soft tissue. Ill-defined osteolytic bone destruction with no sclerosis and with no periosteal reaction is the principal radiologic feature of the malignant fibrous histiocytoma of bone. Therefore, malignant fibrous histiocytoma should be considered in differential diagnosis of primary intraosseous or extraosseous malignancies.
Diagnosis, Differential
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Histiocytoma, Malignant Fibrous
;
Sclerosis
2.Primary Malignant Fibrous Histiocytoma of the Jejunum.
Dae Woo YOO ; Dong Hoon SHIN ; Myeng Sun PARK ; Bang HUR ; Choong Han LEE
Journal of the Korean Surgical Society 2001;60(5):575-578
Malignant fibrous histiocytoma (MFH) occurs primarily in the extremities and trunk, however primary malignant fibrous histiocytoma of the alimentary tract, particularly of the jejunum, is uncommon. This case report presents a case of malignant fibrous histiocytoma as the primary lesion of the jejunum in a 42-year-old male patient with a 10-day history of melena. A small bowel tumor was resected without complication. The final diagnosis was based on the pathological report of the surgical specimen.
Adult
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Diagnosis
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Extremities
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Histiocytoma, Malignant Fibrous*
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Humans
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Jejunum*
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Male
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Melena
3.Cytologic Diagnosis of Malignant Fibrous Histiocytoma in Pleural Fluid: A Case Report.
Hwa Eun OH ; Yoo Hoon KIM ; Seong Jin CHO ; Young Sik KIM ; In Sun KIM
Korean Journal of Cytopathology 1995;6(1):80-83
Malignant fibrous histiocytoma is the most common soft tissue sarcoma of late adult life, but it is rare in the pleura. We recently experienced a case of cytology of malignant fibrous histiocytoma in pleural fluid. The smear revealed histiocytic malignant cells, spindle malignant cells and inflammatory cells. The histiocytic cells showed abundant, pale cytoplasm and ovoid, irregular, eccentrically placed nuclei. The spindle cells showed elongated nuclei. Intercellular collagen was also present.
Adult
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Collagen
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Cytoplasm
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Diagnosis*
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Histiocytoma, Malignant Fibrous*
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Humans
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Pleura
;
Sarcoma
4.MR Imaging Findings of Malignant Fibrous Histiocytoma of Bone.
Jeong Hoon LEE ; Ki Soo KIM ; Byung Hee LEE ; Young Soo DO ; Kie Hwan KIM ; Soo Yil CHIN
Journal of the Korean Radiological Society 1996;34(2):257-261
PURPOSE: The purpose of this study is to assess magnetic resonance (MR) imaging findings of malignant fibrous histiocytoma (MFH) of bone and to evaluate the role of contrast-enhanced MR imaging in the diagnosis of bone MFH. MATERIALS AND METHODS: MR imagings of pathologically proven bone MFH in ten patients were reviewed. Enhanced study was also performed with Gd-DTPA. The MR images were evaluated for signal intensity, homogeneity, marginal definition, presence of internal septation, cortical destruction, soft tissue extension, joint involvement and contrast enhancement. RESULTS: Tumors showed iso- or slightly high signal intensity to muscle on T1-weighted images and heterogeneously high signal intensity on T2-weighted images. Four cases showed poor-marginated borderon T2-weighted images and four cases had internal septa. Eight of nine patients with intravenous administration of Gd-DTPA showed contrast enhancement, five were heterogeneous and three were homogeneous. All cases showed cortical destruction and soft tissue extension. Five cases showed joint involvement. CONCLUSION: Bone MFH showed similar MR imaging findings of soft tissue MFH or other malignant bone tumors, but joint involvement was suggestive finding of bone MFH.
Administration, Intravenous
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Diagnosis
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Gadolinium DTPA
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Histiocytoma
;
Histiocytoma, Malignant Fibrous*
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Humans
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Joints
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Magnetic Resonance Imaging*
5.A Case of Fibrous Histiocytoma in Parotid Gland.
Seung Won CHUNG ; Ho Suk CHU ; Jung Soo WOO ; Kwang Yoon JUNG
Korean Journal of Otolaryngology - Head and Neck Surgery 2004;47(2):174-176
Fibrous histiocytoma is a tumor of a biphasic cell population of fibroblasts and histiocytes. It usually occurs in the sun-exposed skin and orbital tissue but it has also been found in the upper aerodigestive tract, salivary gland, and deep layers of scalps and face. Fibrous histiocytoma in the parotid gland is extremely rare. It must be distinguished from other spindle cell tumors of parotid gland, particularly those of epithelial and myoepithelial origins. In immunohistochemical studies, antibody markers against vimentin and smooth muscle-specific actin lead to the diagnosis of fibrous histiocytoma. The malignant fibrous histiocytoma can be differentiated by its histopathology, since it consists of pleomorphism of cells, abundant mitotic figure, atypic mitotic figure and other tissue invasion. The clinical features such as rapid growth and distant organ metastasis allow a diagnosis of malignant variants. Treatment of benign fibrous histiocytoma can be made by a wide local excision without the sacrifice of near organs.
Actins
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Diagnosis
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Fibroblasts
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Histiocytes
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Histiocytoma
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Histiocytoma, Benign Fibrous*
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Histiocytoma, Malignant Fibrous
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Neoplasm Metastasis
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Orbit
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Parotid Gland*
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Salivary Glands
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Scalp
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Skin
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Vimentin
6.Cutaneous Metastatic Undifferentiated Pleomorphic Sarcoma from a Mediastinal Sarcoma.
Do Seon JEONG ; Dong Hwa PARK ; Chi Yeon KIM
Annals of Dermatology 2015;27(3):310-314
Undifferentiated pleomorphic sarcoma, known as malignant fibrous histiocytoma, is a malignant neoplasm that arises in both soft tissue and bones. In 2002, the World Health Organization declassified malignant fibrous histocytoma as a formal diagnostic entity and renamed it 'undifferentiated pleomorphic sarcoma not otherwise specified.' It most commonly occurs in the lower extremities and rarely metastasizes cutaneously. We report a case of cutaneous metastatic undifferentiated pleomorphic sarcoma of the buttocks occurring in a 73-year-old man diagnosed with mediastinal sarcoma 4 years previously. He first noticed the mass approximately 2 months previously. Histological findings with immunomarkers led to a final diagnosis of cutaneous metastatic sarcoma from mediastinal undifferentiated pleomorphic sarcoma.
Aged
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Buttocks
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Diagnosis
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Histiocytoma, Malignant Fibrous
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Humans
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Lower Extremity
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Sarcoma*
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World Health Organization
7.Malignant Fibrous Histiocytoma of the Spermatic Cord: A Case Report.
Ji Yoon KIM ; Seong Ho LEE ; Hee Chang JUNG ; Dong Sug KIM ; Jae Ho CHO
Yeungnam University Journal of Medicine 2003;20(1):85-91
Malignant fibrous histiocytoma (MFH) of the spermatic cord represents an uncommon location for the most common soft tissue tumor in adults. MFH of the spermatic cord is extremely rare. No case report has been described in the Korean literature. We report a case of malignant fibrous histiocytoma, myxoid type, arising from left spermatic cord. A 77-year-old male presented with a painless left upper scrotal mass for 5 months. Simple mass excision was performed for a diagnosis. Grossly, the mass closely contacted with the left spermatic cord. Since a myxoid type of malignant fibrous histiocytoma was diagnosed from histopathological findings, left radical orchiectomy with high ligation of the spermatic cord was performed additionally. There were no evidence of local recurrence or metastasis at 6 months after surgery.
Adult
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Aged
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Diagnosis
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Histiocytoma, Malignant Fibrous*
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Humans
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Ligation
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Male
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Neoplasm Metastasis
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Orchiectomy
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Recurrence
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Sarcoma
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Spermatic Cord*
8.Undifferentiated Pleomorphic Sarcoma in Mandible.
Chul Hwan KIM ; Jong Won JANG ; Moon Young KIM ; Yong Hwan KIM ; Hang Gul KIM ; Joo Hwan KIM
Maxillofacial Plastic and Reconstructive Surgery 2014;36(6):303-307
Undifferentiated pleomorphic sarcoma (UPS), previously known as malignant fibrous histiocytoma, occurs commonly in the soft tissues in adult, but is rare in the maxillofacial region. It consists of undifferentiated mesenchymal tumor cells resembling histiocytes and fibroblasts. The purpose of this article is to report a case of UPS in the mandible. A 44-year-old patient presented with a painful growing mass in the mandible of two months' duration. Computed tomography and positron emission tomography-computed tomography revealed an ill-defined heterogenous, hypermetabolic mass about 4 cm in size in the left mandible invading adjacent soft tissues. A left mandiblulectomy and reconstruction with a fibular free flap were performed. Immunohistochemical study gave a diagnosis of UPS. The patient was referred for adjuvant chemotherapy after surgical removal of the tumor.
Adult
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Chemotherapy, Adjuvant
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Diagnosis
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Electrons
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Fibroblasts
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Free Tissue Flaps
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Histiocytes
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Histiocytoma, Malignant Fibrous
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Humans
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Mandible*
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Sarcoma*
9.A Case of Malignant Fibrous Histiocytoma of the Left Atrium.
Eon Tak LEE ; Dong Soo KIM ; Kung Soon LEE ; Jong Soo WOO ; Kwang Hun CHO ; In Suk LIM
Korean Circulation Journal 1989;19(3):503-510
Primary malignant neoplasms of the heart are very rare disorders, which are found at less 1/1000 necropsies. These malignancies are almost exclusively sarcomas and histologically assume a wide veriety of morphological subtypes, angiosarcomas, rhabdomysarcomas, and fibrosarcomas(or MFH) being the most frequent. We experienced a case in which left atrial myxoma was suspected by 2-D echocardigraphy and the histologic diagnosis of promary MFH was confirmed by operation. A 45-year old woman with primary MFH arising from posterior wall of left atrium, interatrial septum and mitral annulus is presented with a brief view of the literatures. The patient was admitted to our hospital on March 1988, because of exertional dyspnea and intermittent palpitation resction of the masses. To date, more than thirteen months after surgery, the patient is alive and well in state of NYHA class II.
Diagnosis
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Dyspnea
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Female
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Heart
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Heart Atria*
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Hemangiosarcoma
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Histiocytoma, Malignant Fibrous*
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Humans
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Middle Aged
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Myxoma
;
Sarcoma
10.Progression of Dermatofibrosarcoma Proruberans to Malignant Fibrous Histiocytoma: Report of a case.
Hye Rim PARK ; Eun Ha JUNG ; Jin Hee SOHN
Korean Journal of Pathology 1997;31(12):1324-1327
A 52-year-old woman was admitted with a palpable mass on the abdominal wall. This tumor had developed at the same site of a previously resected dermatofibrosarcoma protuberans. The biopsy specimen from the recurrent tumor revealed malignant fibrous histiocytoma. Immunohistochemistry with anti-CD34 antibody revealed diffuse linear positivity on the tumor cells of dermatofibrosarcoma protuberans and negativity on malignant fibrous histiocytoma. Anti CD34 antibody was valuable for a differential diagnosis of these two lesions.
Abdominal Wall
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Biopsy
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Dermatofibrosarcoma*
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Diagnosis, Differential
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Female
;
Histiocytoma, Malignant Fibrous*
;
Humans
;
Immunohistochemistry
;
Middle Aged