1.Mutations in EDA and EDAR Genes in a Large Mexican Hispanic Cohort with Hypohidrotic Ectodermal Dysplasia.
Julio C SALAS-ALANIS ; Eva WOZNIAK ; Charles A MEIN ; Carola C DURAN MCKINSTER ; Jorge OCAMPO-CANDIANI ; David P KELSELL ; Rong HUA ; Maria L GARZA-RODRIGUEZ ; Keith A CHOATE ; Hugo A BARRERA SALDANA
Annals of Dermatology 2015;27(4):474-477
No abstract available.
Cohort Studies*
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Ectodermal Dysplasia 1, Anhidrotic*
;
Hispanic Americans*
;
Humans
2.Choosing Optimal STR Markers for Quality Assurance of Distributed Biomaterials in Biobanking.
Tae Hoon CHUNG ; Heejung LEE ; Mihee LEE ; Jae Pil JEON ; Kisang KIM ; Bok Ghee HAN
Genomics & Informatics 2009;7(1):32-37
The quality assurance (QA) is of utmost importance in biobanks when archived biomaterials are distributed to biomedical researchers. For sample authentication and cross-contamination detection, the two fundamental elements of QA, STR genotyping is usually utilized. However, the incorporated number of STR markers is highly redundant for biobanking purposes, resulting in time and cost inefficiency. An index to measure the cross-contamination detection capability of an STR marker, the mixture probability (MP), was developed. MP as well as other forensic parameters for STR markers was validated using STR genotyping data on 2328 normal Koreans with the commercial AmpFlSTR kit. For Koreans, 7 STR marker (D2S1338, FGA, D18S51, D8S1179, D13S317, D21S11, vWA) set was sufficient to provide discrimination power of ~10(-10) and cross-contamination detection probability of ~1. Interestingly, similar marker sets were obtained from African Americans, Caucasian Americans, and Hispanic Americans under the same level of discrimination power. Only a small subset of commonly used STR markers is sufficient for QA purposes in biobanks. A procedure for selecting optimal STR markers is outlined using STR genotyping results from normal Korean population.
African Americans
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Biocompatible Materials
;
Discrimination (Psychology)
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Hispanic Americans
;
Humans
;
Microsatellite Repeats
3.The effect of western adaptation of Hispanic-Americans on their assessment of Korean facial profiles.
Leo TOURENO ; Yoon Ah KOOK ; Mohamed BAYOME ; Jae Hyun PARK
The Korean Journal of Orthodontics 2014;44(1):28-35
OBJECTIVE: To determine Korean facial profile preferences based on lip position as assessed by Hispanic-Americans of varying western adaptation levels and to determine whether the age and sex of the rater had any influence. METHODS: For this study, 132 Hispanic-Americans and 68 Caucasians of varying age, sex and western adaptation levels volunteered to rate their preference of Korean male and female facial silhouettes having lips ranging from retruding to protruding. The Hispanic-Americans were also asked to complete a Bidimensional Acculturation Scale questionnaire to determine their western adaptation status: low-acculturated Hispanics (LAH; lesser western-adapted Hispanic participants) or high-acculturated Hispanics (HAH; higher western-adapted Hispanic participants). RESULTS: The LAHs preferred significantly more retruded lip positions (p < 0.05) while HAHs showed some similarities with Caucasian participants in the results for the Korean male profile, even though HAHs preferred more retruded lip positions for the Korean female profile than Caucasians did (p < 0.05). The age and sex of raters did not influence the preference of facial profiles (p > 0.05). CONCLUSIONS: The results of this study suggest that Hispanic-Americans prefer a flatter Korean lip profile. It would be prudent for orthodontists to offer patients the option of altering lip profile through orthodontic and/or orthognathic surgery treatments.
Acculturation
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Female
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Hispanic Americans
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Humans
;
Lip
;
Male
;
Orthodontics
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Orthognathic Surgery
;
Surveys and Questionnaires
4.Employers' Perceptions of Intimate Partner Violence among a Diverse Workforce.
Laura J SAMUEL ; Carrie TUDOR ; Marc WEINSTEIN ; Helen MOSS ; Nancy GLASS
Safety and Health at Work 2011;2(3):250-259
OBJECTIVES: Intimate partner violence (IPV) is a significant global public health concern, affecting 5.3 million US individuals annually. An estimated 1 in 3 women globally are abused by an intimate partner in their lifetime, and the effects carry over into the workplace. This article examines employers' perceptions of IPV in the workplace, targeting supervisors of Latina employees. METHODS: Fourteen employers and supervisors of small service-sector companies in Oregon were interviewed using semi-structured interviews. Interpretive description was used to identify themes. These qualitative interviews preceded and helped to formulate a larger workplace intervention study. RESULTS: The following themes were found and are detailed: (1) factors associated with recognizing IPV in the workplace, (2) effects of IPV on the work environment and (3) supervisors' responses to IPV-active vs. passive involvement. Also, supervisors' suggestions for addressing IPV in the workplace are summarized. CONCLUSION: These findings demonstrate the need for more IPV-related resources in the workplace to be available to supervisors as well as survivors and their coworkers. The needs of supervisors and workplaces vary by site, demonstrating the need for tailored interventions, and culturally appropriate workplace interventions are needed for Latinas and other racially and ethnically diverse populations.
Domestic Violence
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Employment
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Female
;
Hispanic Americans
;
Humans
;
Oregon
;
Public Health
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Survivors
;
Violence
5.The Effects of Sociodemographic Factors on Psychiatric Diagnosis.
Mal Rye CHOI ; Hun Jeong EUN ; Tai P YOO ; Youngmi YUN ; Christopher WOOD ; Michael KASE ; Jong Il PARK ; Jong Chul YANG
Psychiatry Investigation 2012;9(3):199-208
OBJECTIVE: Several studies have reported that ethnic differences influence psychiatric diagnoses. Some previous studies reported that African Americans and Hispanics are diagnosed with schizophrenia spectrum disorders more frequently than Caucasians, and that Caucasians are more likely to be diagnosed with affective disorders than other ethnic groups. We sought to identify associations between sociodemographic factors and psychiatric diagnosis. METHODS: We retrospectively examined the medical records of all psychiatric inpatients (ages over 18 years) treated at Kern county mental hospital (n=2,051) between July 2003 and March 2007 for demographic, clinical information, and discharge diagnoses. RESULTS: African American and Hispanic males were more frequently diagnosed with schizophrenia spectrum disorders than Caucasians, whereas Caucasian females were more frequently diagnosed with affective disorders than females in the other ethnic groups, suggesting that patient ethnicity and gender may influence clinical diagnoses. Demographic variables, that is, a lower education, failure of marriage, homelessness, and low quality insurance, were found to be significantly associated with a diagnosis of schizophrenia spectrum disorders after adjusting for clinical variables. And, the presence of a family psychiatric history, failure of marriage, not-homelessness, and quality insurance were found to be associated with a diagnosis of affective disorders. CONCLUSION: Our results show that these demographic factors, including ethnicity, have effects on diagnoses in psychiatric inpatients. Furthermore, these variables may help prediction of psychiatric diagnoses.
African Americans
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Demography
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Ethnic Groups
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Female
;
Hispanic Americans
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Homeless Persons
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Hospitals, Psychiatric
;
Humans
;
Inpatients
;
Insurance
;
Male
;
Marriage
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Medical Records
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Mental Disorders
;
Mood Disorders
;
Retrospective Studies
;
Schizophrenia
6.Intracranial Atherosclerosis: From Microscopy to High-Resolution Magnetic Resonance Imaging.
Wen Jie YANG ; Ka Sing WONG ; Xiang Yan CHEN
Journal of Stroke 2017;19(3):249-260
Intracranial atherosclerosis is one of the leading causes of ischemic stroke and occurs more commonly in patients of Asian, African or Hispanic origin than in Caucasians. Although the histopathology of intracranial atherosclerotic disease resembles extracranial atherosclerosis, there are some notable differences in the onset and severity of atherosclerosis. Current understanding of intracranial atherosclerotic disease has been advanced by the high-resolution magnetic resonance imaging (HRMRI), a novel emerging imaging technique that can directly visualize the vessel wall pathology. However, the pathological validation of HRMRI signal characteristics remains a key step to depict the plaque components and vulnerability in intracranial atherosclerotic lesions. The purpose of this review is to describe the histological features of intracranial atherosclerosis and to state current evidences regarding the validation of MR vessel wall imaging with histopathology.
Asian Continental Ancestry Group
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Atherosclerosis
;
Autopsy
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Hispanic Americans
;
Humans
;
Intracranial Arteriosclerosis*
;
Magnetic Resonance Imaging*
;
Microscopy*
;
Pathology
;
Stroke
7.Impact of Age on Clinicopathological Features and Survival of Patients with Noncardia Gastric Adenocarcinoma.
Marita C BAUTISTA ; Sheng Fang JIANG ; Mary Anne ARMSTRONG ; Debbie POSTLETHWAITE ; Dan LI
Journal of Gastric Cancer 2014;14(4):238-245
PURPOSE: Gastric cancer often occurs in the elderly but is uncommon in young individuals. Whether young patients have different clinical behaviors and outcomes from those of older patients remain unclear. MATERIALS AND METHODS: We identified 1,366 cases of newly diagnosed noncardia gastric adenocarcinoma from the Kaiser Permanente Northern California Cancer Registry between 2000 and 2010. We then compared the clinicopathological features and survival among the different age groups. RESULTS: The male : female ratio differed significantly between the younger and older patient groups (0.84 in age <50 years vs. 1.52>60 years, P<0.01). More younger patients were Hispanic (54% patients <40 years vs. 19% patients > or =70 years, P<0.0001), while more older patients were Caucasian (49% patients > or =70 years vs. 15% patients <40 years; P<0.0001). The diffuse/mixed histological type was more prevalent in younger patients (70% patients <40 years vs. 27% patients > or =70 years; P<0.0001), whereas the intestinal type was more frequent in older patients (71% in patients > or =70 years vs. 30% in patients <40 years; P<0.0001). Poorly differentiated adenocarcinoma was more common in the younger patients (80% in patients <40 years vs. 60% in patients > or =70 years; P=0.016). Survival rates at 1, 2, and 5 years gradually declined with increasing age (overall P=0.0002). CONCLUSIONS: Young patients with gastric cancer had more aggressive disease but higher overall survival rates than older patients. Younger Hispanic patients and older Caucasian patients were more likely to be diagnosed with gastric cancer. These differences may be due to biological predisposition and/or environmental exposure.
Adenocarcinoma*
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Aged
;
California
;
Environmental Exposure
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Ethnic Groups
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Female
;
Hispanic Americans
;
Humans
;
Male
;
Outcome Assessment (Health Care)
;
Stomach Neoplasms
;
Survival Rate
8.Recognition of body image and food behavior factors among middle school students in San Francisco area.
Nutrition Research and Practice 2007;1(1):36-41
The purpose of this study was to determine the recognition of body image and food behavior factors according to the BMI. The subjects of this study were 242 7th grade students resided in San Francisco area. The degree of recognition for self-estimated physique of subjects by gender and by race showed no significant differences by gender but significant differences by race, showing that 20.0% was considered as underweight in Asian and 7.5% was considered as underweight in White students. This showed the same tendency as actual physique status (BMI). Also, the ratio of being recognized as more than overweight was 17.3% in Asian, 23.3% in Hispanic, and 13.4% in White students. In case of female students, the ratio of dieting experience was 63.3%, and 49.3% of White students and 63.3% of Hispanic students experienced dieting. In case of students answered not healthy, their body weight were significantly higher than those answered as healthy, and the BMI was also over 19, showing significant differences. Thus cases that answered as not healthy had greater body weight and BMI. Also it showed that frequent dieting experience is related to higher height and weight. The analysis of food behavior factors perceived by body shape showed that the group perceived itself as overweight consumed more 'fast food' but had low scores in 'vegetables' intake, with frequent intake of 'soda' and tendency to 'overeat'. Also, the tendency for 'balanced life' was significantly lower and for skipping breakfast was significantly higher, suggesting problematic food behavior.
Asian Continental Ancestry Group
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Body Image*
;
Body Weight
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Breakfast
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Continental Population Groups
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Diet
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Female
;
Hispanic Americans
;
Humans
;
Overweight
;
Thinness
9.Evaluation of emotion-based messages designed to motivate Hispanic and Asian parents of early adolescents to engage in calcium-rich food and beverage parenting practices.
Jinan Corinne BANNA ; Marla REICKS ; Carolyn GUNTHER ; Rickelle RICHARDS ; Christine BRUHN ; Mary CLUSKEY ; Siew Sun WONG ; Scottie MISNER ; Nobuko HONGU ; N Paul JOHNSTON
Nutrition Research and Practice 2016;10(4):456-463
BACKGROUND/OBJECTIVES: Setting healthful beverage expectations, making calcium-rich foods and beverages (CRF/B) available, and role modeling are parenting practices promoting calcium intake among early adolescents. This study aimed to evaluate emotion-based messages designed to motivate parents of early adolescents to perform these practices. SUBJECTS/METHODS: Emotion-based messages were developed for each parenting practice and tested in 35 parents from 5 states. Findings were used to modify messages and develop a survey administered via Amazon MechanicalTurk to a convenience sample of Asian (n = 166) and Hispanic (n = 184) parents of children 10-13 years. Main outcome measures were message comprehension, motivation, relevance, acceptability, and novelty. Engagement in the parenting practices was also assessed. RESULTS: Message comprehension was acceptable for the majority of parents. Most also agreed that messages were motivational (setting healthful beverage expectations (69.0%), making CRF/B available (67.4%), and role modeling (80.0%)), relevant and acceptable. About 30-50% indicated they had not seen the information before. Many parents indicated they were already engaging in the practices (> 70%). No racial/ethnic differences were observed for responses to messages or engaging in parenting practices. CONCLUSIONS: Results indicate that emotion-based messages designed to motivate parents to engage in parenting practices that promote calcium intake among early adolescents were motivating, relevant, and acceptable.
Adolescent*
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Asian Continental Ancestry Group*
;
Beverages*
;
Calcium
;
Child
;
Comprehension
;
Hispanic Americans*
;
Humans
;
Motivation
;
Outcome Assessment (Health Care)
;
Parenting*
;
Parents*
10.One Menu Please: Parents Want Affordable, Right-sized Portions for Their Children in Restaurants.
Seung Hee LEE-KWAN ; Sohyun PARK ; Leah MAYNARD ; Heidi M BLANCK
Clinical Nutrition Research 2018;7(4):241-247
One contributing factor to the obesity epidemic is the large portion sizes served in restaurants. However, no study has looked at the parents' desire for smaller-portioned meals for their children at restaurants in the U.S. This study examined parents' preference for restaurants to offer smaller, lower-priced child portions for their children and reasons for the preference. Multivariable logistic regression was used to estimate adjusted odds ratios (ORs) for the association between preference for child portions and variables on parental sociodemographic characteristics and weight status. About 70% of parents said they would prefer that restaurants offer smaller, lower-priced child portions of all menu offerings. The adjusted odds of preferring child portions were significantly higher among Hispanic parents (OR, 1.95 vs. non-Hispanic whites) but significantly lower among parents with lower education (≤ high school, OR, 0.64; some college, OR, 0.69 vs. college graduate) and parents residing in the Midwest or West (Midwest, OR, 0.61; West, OR, 0.58 vs. South). The most common reason for preferring child portions of all meals was “wanting my child to eat healthier foods that are not offered on the children's menu” (72%). These findings can be used to encourage restaurants and other venues to consider offering child portions of healthier menu items.
Child*
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Education
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Fast Foods
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Hispanic Americans
;
Humans
;
Logistic Models
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Meals
;
Obesity
;
Odds Ratio
;
Parents*
;
Portion Size
;
Restaurants*