1.Albumin-refractory Transudative Ascites for the Diagnosis of Protein-losing Gastric Cancer: A Case Report
Naoya MIZUTANI ; Hiroyuki MORI ; Tsuneaki KENZAKA
An Official Journal of the Japan Primary Care Association 2024;47(3):89-98
A 63-year-old man with schizophrenia presented to our hospital with a chief complaint of anorexia and edema in the lower legs for the past month. Upper gastrointestinal endoscopy revealed a gross type 3 gastric carcinoma (pathology: tubular adenocarcinoma, moderately differentiated type) from the upper gastric body to the gastric antrum. His serum total protein level was 4.7 g/dL and serum albumin concentration was 1.5 g/dL. Contrast-enhanced computed tomography, magnetic resonance imaging, and examination of ascites showed no evidence of distant metastases. Hypoalbuminemia was refractory to albumin administration with no evidence of cancerous peritonitis on staging laparoscopy. Gastrointestinal scintigraphy confirmed protein leakage from the gastric tumor into the gastrointestinal tract. We reviewed the literature and identified 34 other cases of protein-losing gastric cancer, which were used to comprehensively elucidate its clinical features. Borrmann type 0 or 1 tumors of the gastric body or antecubital area, with a maximum tumor diameter of nearly 10 cm and a cauliflower-like appearance, are highly suggestive of protein-losing gastric cancer. In conclusion, 99mTc-HSA scintigraphy and staging laparoscopy should be performed aggressively to differentiate protein-losing gastric cancer tumor from cancerous peritonitis.
2.Stanford Type A Acute Aortic Dissection Case Caused by Blunt Chest Trauma
Hiroyuki Saisho ; Satoru Tobinaga ; Yuichiro Hirata ; Kumiko Wada ; Ryusuke Mori ; Tomokazu Ohno ; Atsuhisa Tanaka ; Shinichi Hiromatsu ; Hidetoshi Akashi ; Hiroyuki Tanaka
Japanese Journal of Cardiovascular Surgery 2013;42(2):159-162
A 31-year-old man fell into syncope caused by compression by a machine in his factory. He was taken to the nearest hospital at once for treatment. His chest X-ray seemed normal and his general condition improved. He received no medical treatment and was allowed to return home. Two days later, he went to the hospital for further investigation, and contrast-enhanced chest computed tomography (CT) was performed. Chest CT showed aortic dissection from the ascending aorta to the aortic arch. Therefore, he was admitted for bed rest with antihypertensive therapy. He was discharged on the 35th day after the accident. However, the diameter of the ascending aorta was found to have become dilated, and so he underwent ascending aorta and hemiarch replacement at our hospital. His postoperative course was uneventful, and he was discharged on the 16th postoperative day. We report a rare case of an acute aortic dissection caused by blunt chest trauma.
3.Reconstruction of the Left Ventricular Outflow Tract with a Rolled Equine Pericardium for Annular Abscess after Aortic Root Replacement
Yuichiro Hirata ; Shuji Fukunaga ; Tomokazu Kosuga ; Hiroyuki Saisyo ; Kumiko Wada ; Ryusuke Mori ; Hidetoshi Akashi ; Shigeaki Aoyagi
Japanese Journal of Cardiovascular Surgery 2012;41(4):200-203
A 61 year-old man was admitted with fever and chest discomfort. He had undergone aortic root replacement for annuloaortic ectasia at age 57. Computed tomography showed a pseudoaneurysm and an abscess formation around the aortic root. Prosthetic valve endocarditis was diagnosed and the underwent repeat aortic root replacement. After debridement and irrigation of the abscess cavity, the left ventricular outflow tract was reconstructed with an equine pericardium, which was rolled to form a conduit. The pericardial conduit was securely sutured to the healthy left ventricular wall and the mitral annulus. A 25 mm-Freestyle valve was then sutured to the distal end of the conduit. The previous prosthetic vascular graft was removed and Completely replaced with a new prosthesis. This method provided secure fixation of a new prosthetic valved conduit to the normal left ventricular tissue with an excellent operative visual field.
4.Evaluation of the Interview Skills at the Opening of the Medical Interviewing.
Hiroki SASAKI ; Tsukasa TSUDA ; Nobutaro BAN ; Ryuki KASSAI ; Noriaki OCHI ; Akira MATSUSHITA ; Takafumi MORI ; Hiroyuki OGASAWARA
Medical Education 1996;27(3):167-170
We evaluated the interview skills of 46 sixth year medical students (32 men, 14 women) in our outpatient clinic. Six items were evaluated, including the manner in which students responded to patients, the number of times students interrupted patients' statements with closed-ended questions, and the extent to which students maintained eye contact with patients. We found that students interrupted patients every 46.2 seconds on average, and often did not make eye contact with tha patients. It became clear that, although we teach medical interview skills to students, students do not learn these skills very well. We suggest that in order to properly educate medical students, close cooperation between departments is needed.
5.The Influence of Vascular Wall on Wrapping Method in the Canine Aorta.
Tadashi Kinefuchi ; Tuneo Ookuma ; Akira Sato ; Hiroyuki Kaneda ; Mituhiro Takahashi ; Dai Ooe ; Shouzou Mori
Japanese Journal of Cardiovascular Surgery 1995;24(2):71-79
There is still considerable risk when performing anastomotic procedures in the aorta and artificial vessels. The wrapping method is occasionally used as an alternative to solve the problems of hemostasis and reinforcement of the anastomotic portion, however, few data are available on the results of long-term follow up after anastomosis in this area. To define the long-term results for the wrapping method, we evaluated changes in the vascular walls of set intervals. The purpose of this study was to analyze the influence of technical factors and to sutisfy the prerequisites for an ideal wrapping method. A total of 26 mongrel dogs of both sexes were used in this study. We examined changes of the aortic walls microscopically of set intervals after a wrapping method using woven Dacron materials for 4 weeks and 4 months. Another 2 groups (Mesh group and E-PTFE group) were also included in this study. The cause of thinning phenomena of the aortic walls appears to be compression of the anastomotic portion. Wrapping materials resulting in excessively small diameters may cause deleterious compressions of the anastomotic site. Wrapping methods with materials ensuring a larger diameter may play an important role after anastomotic operations for reinforcement and hemostasis.
6.Regional Wall Motion of the Left Ventricle Evaluated by the Centerline Method in Left Ventricular Aneurysmectomy.
Hisato Takagi ; Hajime Hirose ; Yasunobu Furuzawa ; Hiroyuki Yasuda ; Kiyokage Kubo ; Shinji Murakawa ; Yosio Mori ; Hiroshi Takiya
Japanese Journal of Cardiovascular Surgery 1997;26(6):365-370
In 13 patients who underwent left ventriculography both before and after operation, we investigated regional wall motion of the left ventricle (LV) with the centerline method in LV aneurysmectomy. There were no significant differences between preoperative predicted and postoperative ejection fraction. No significant differences were observed between preoperative predicted and postoperative regional wall motion of all segments in all cases and cases without significant stenosis who did not undergo revascularization of the right coronary artery. Postoperative regional wall motion of the inferior wall was significantly better than the preoperative predicted one in cases who underwent revascularization of the right coronary artery with significant stenosis. It is considered that revascularization of the right coronary artery with significant stenosis in LV aneurysmectomy was effective for the improvement of regional wall motion of the inferior wall.
7.Off-Pump Coronary Artery Bypass Grafting in Dialysis Patients.
Hiroyuki Tanaka ; Takashi Narisawa ; Takanobu Mori ; Mikio Masuda ; Takashi Suzuki ; Toshihiro Takaba
Japanese Journal of Cardiovascular Surgery 2002;31(2):105-109
In dialysis cases complicated with ischemic heart disease, there are many problems, such as poor preoperative general condition, calcified aorta, water-electrolyte control, and the necessity for other simultaneous operations. Off-pump coronary artery bypass grafting (OPCAB) was considered very useful in coping with these problems. OPCAB, employed in five cases, was compared with conventional coronary artery bypass grafting with extracorporeal circulation (ECC group, 9 cases). Regarding preoperative coexisting diseases, collagen diseases, porcelain aorta, cerebral infarction, and others were recognized in the OPCAB group in 3 of 5 cases. Emergency operations were performed in 5 of 9 cases in the ECC group, and in 2 of 5 cases in the OPCAB group. The bypass number (3.2 vs. 2.0) and complete revascularization rate (7 of 9 vs. 2 of 5), tended to be higher in the ECC group. The OPCAP group was significantly superior in blood transfusion (6.7 vs. 3.0u), postoperative CK-MB (63 vs. 33u), and the postoperative usual hemodialysis commencing time (4.2 vs. 1.0 day). Concerning use of postoperative IABP (3 of 9 vs. 0 of 5), and postoperative ventilator weaning time (2.7 vs. 1.0 day), a good tendency was shown in the OPCAB group. Although a high mortality rate (2 of 5) was recognized in OPCAB group compared with ECC group (1 of 9), those were urgent cases who had a very poor preoperative condition, and both cases suffered non-cardiac deaths. Excluding special cases, such as an unstable hemodynamic state requiring assisted circulation, and poor coronary run off, OPCAB seems useful for the treatment of coronary artery disease in dialysis patients.
8.Surgery of Abdominal Aortic Aneurysm Associated with Coronary Artery Disease: Simultaneous or Two Staged Operation
Hiroyuki Tanaka ; Takashi Narisawa ; Takanobu Mori ; Mikio Masuda ; Daijirou Kishi ; Takashi Suzuki ; Toshihiro Takaba
Japanese Journal of Cardiovascular Surgery 2003;32(4):197-200
Coronary artery disease (CAD) was evaluated by noninvasive examination in abdominal aortic aneurysm (AAA) patients. A simultaneous operation or a 2-staged operation was performed depending on the seriousness of the condition when both diseases were combined. A total of 36 patients underwent elective repair of AAA between 1996 and 2001. Coronary angiography (CAG) was performed only in patients with suspected CAD by dipyridamole myocardial scintigraphy. Significant CAD was found in 8 patients. Simultaneous operation was performed in 4 patients, and off-pump coronary artery bypass grafting (OPCAB) was performed in all cases of simultaneous operation. In 4 patients receiving 2-staged operations, 1 standard coronary artery bypass grafting (CABG), 1 OPCAB and 2 percutaneous transluminal coronary angioplasties (PTCA) were performed prior to AAA surgery. Twenty-eight patients underwent only AAA operation. Though there were no incidents of perioperative myocardial infarction or cardiac related deaths in this group, 2 patients died due to other causes (hemorrhage and duodenal perforation). In the 8 patients associated with CAD, 1 patient died of MNMS after simultaneous operation. The other 7 patients revived their social function soon of the discharge. Dipyridamole cardiac scintigraphy was considered to be an effective examination for evaluation of CAD in AAA patients. There was no need to perform CAG in all AAA patients. The policy of choosing simultaneous operation or 2-staged operation according to the seriousness of the 2 diseases seemed to be appropriate.
9.Renal Function and Mortality in Patients with Infective Endocarditis
Yuji Nishizaki ; Takuya Watanabe ; Yasuharu Tokuda ; Miyuki Futatsuyama ; Keiichi Furukawa ; Nobuyoshi Mori ; Yusuke Tsugawa ; Heath Yuki ; Keiichi Tamagaki ; Fumika Taki ; Hiroyuki Yamamoto ; Takafumi Ohiwa ; Yasuhiro Komatsu
General Medicine 2012;13(1):19-24
Objectives: Infective endocarditis (IE) has an extremely poor prognosis unless appropriate treatment is received. Hemodialysis patients with IE show higher rates of morbidity and mortality in comparison with non-dialysis patients with IE. We focused on hemodialysis patients, as well as patients in other stages of chronic kidney disease. We sought to assess the relationship between renal function and mortality in patients with IE.
Methods: We carried out a retrospective cohort study on 45 consecutive patients with IE in an urban teaching hospital between November 2003 and August 2008. We collected demographic and clinical data as well as pre- and post-discharge outcomes. Patients were subdivided into four groups according to their eGFR level at admission: A: eGFR≧60 ml/min/1.73 m2 (n=23); B: eGFR 30-59 ml/min/1.73 m2 (n=15); C: eGFR<30 ml/min/1.73 m2 (n=3); and, D: dialysis patients (n=3). It was not possible to determine the outcome status of one patient. The Trend Test was used to evaluate the association between renal function and mortality.
Results: There were 29 male and 16 female patients with IE and the mean age was 67.9+-17.6 (SD). There were 10 diabetic patients (22%). Thirty-nine patients (84%) were either discharged or transferred to another hospital. Seven patients (16%) died: two (9%) Group A patients; three (20%) Group B patients; no Group C patients; and, two (67%) Group D patients. Patients with lower eGFR had higher mortality rates (Trend Test, P=0.046).
Conclusion: We presume a trend towards a higher mortality rate in conjunction with advancing CKD stage.
10.Difficulties in daily life of post thoracic esophagectomy cancer patients after hospital discharge
Shigeaki Watanuki ; Keiko Iino ; Yurie Koyama ; Miho Kurihara ; Chisato Ichikawa ; Kyoko Okada ; Hideo Uesugi ; Chie Asanuma ; Hiroyuki Daiko ; Takeo Fujita ; Kyoko Suzuki ; Chihoko Wada ; Michiko Mori ; Yoko Hisabe ; Kaori Yagasaki ; Hiroko Komatsu
Palliative Care Research 2014;9(2):128-135
Purpose: This study aimed at identifying difficulties among post thoracic esophagectomy cancer patients during outpatient follow-up. Methods: Patients who had radical esophagectomy at a cancer center hospital in Japan were prospectively observed and were interviewed by a certified nurse assigned at esophageal surgical outpatient division. Their responses were documented in medical records and were analyzed by content analysis method. This study was approved by the study hospital's research ethics committee. Results: The data from 66 patients were obtained. Content analysis yielded 221 extracts, 25 categories, and 65 codes of difficulties, including: concerns or signs/symptoms associated with dietary intake, physical activity, and anxiety. Implications: The majority of post-thoracoabdominal esophagectomy patients experienced multiple dysfunctions and symptoms after discharge. The results underscore the significance of nurses' role in assessing and instructing patients to address these issues.