We perfomed an aortic valve replacement and intraoperative plasma exchange with Cell Saver 4® made by Haemonetics for removal of bilirubin. Diluted blood after cardiopulmonary bypass and suctioned blood (total volume 11, 300ml) was washed, concentrated and transfused. Plasma bilirubin level was decreased to 5.4mg/dl from 9.9mg/dl during operation. It was concluded that intraoperative plasma excange with Cell Saver 4® was safe and effective technique for removal of bilirubin during open heart surgery.
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