1.Staged Arterial Switch Operation without Homologous Blood Transfusion
Takashi Tominaga ; Yukihiro Takahashi ; Nobuyuki Kobayashi ; Dai Nishina ; Toshio Kikuchi ; Ryo Hoshino ; Masahito Yamashiro ; Ikuko Shibasaki ; Kayoko Kobayashi ; Hiroki Kouno
Japanese Journal of Cardiovascular Surgery 2004;33(2):114-117
Staged arterial switch operation without homologous blood transfusion was successfully performed in 5 patients weighing 4.1-11.0kg (double outlet right ventricle: 2 cases, transposition of great arteries: 3 cases). The postoperative hemodynamics and respiratory status were uneventful in all patients (initial central venous pressure after ICU admission: 9.0-14.5cmH2O, mean 12.5cmH2O, duration of intubation: 3.5-18.0h, mean 7.8h). Autologous blood donation immediately after induction of anesthesia and minimization of bypass circuit were effective methods for open heart surgery without homologous blood transfusion, particularly in staged arterial switch operation requiring prolonged cardiopulmonary bypass.
2.A Study on the Usefulness of a Simple Lipid Measurement for the Early Detection of Dyslipidemia and Recognition of Dyslipidemia among Local Residents
Hiroki Iwata ; Ryo Masuo ; Mitsuhiro Okazaki ; Masakatsu Fukumoto ; Kazuko Fujimoto ; Noriko Kobayashi ; Katsunori Yamaura
Japanese Journal of Social Pharmacy 2016;35(2):80-86
Approximately 14.1 million patients have dyslipidemia in Japan. Promotion of self-medication for the prevention of dyslipidemia is needed. After a change in law in 2014, residents of Japan are allowed to measure HbA1c, cholesterol, and triglyceride levels by self-blood sampling from the fingers under the guidance of pharmacists. In this study, we held an event to measure the lipid levels within a community and evaluated the usefulness of a simple measurement for the early detection of dyslipidemia. Furthermore, we surveyed community members’ knowledge of dyslipidemia by self-questionnaires. Of the 48 local residents who came to the event, 45 had their lipids measured and answered the questionnaires. In 12 applicants, HDL-cholesterol or non-HDL-cholesterol, which are not affected by meals, exceeded the standard range. In the questionnaire study, 89% of applicants selected arteriosclerosis as the main consequence of dyslipidemia. Additionally, over 82% of applicants selected blue-backed fish, dietary fiber, and soybeans as food items that inhibit the rise in lipid levels. However, only 31% of applicants recognized that fruits also affect lipid levels. Although it was disappointing that 60% of applicants did not know that they could measure HbA1c and lipids at community pharmacies, 62% desired measurement of those levels in the future. This study suggested that the simple lipid measurement is useful for the early detection of dyslipidemia but local residents need to be informed about it. Furthermore, improvement in the recognition of dyslipidemia by local residents is needed.
3.A Case of Acute Arterial Occlusion of the Lower Extremity Caused by Huge Vegetation of Prosthetic Valve Endocarditis
Kizuku Yamashita ; Tomoyuki Fujita ; Hiroki Hata ; Yusuke Shimahara ; Shunsuke Sato ; Junjiro Kobayashi
Japanese Journal of Cardiovascular Surgery 2013;42(4):284-288
A 79-year-old woman with prosthetic valve endocarditis (PVE) on aortic position underwent re-aortic valve replacement. Although emergency operation was indicated due to huge vegetation over 20 mm in diameter attached to the prosthesis shown by preoperative transesophageal echocardiography, intraoperative transesophageal echocardiography showed disappearance of the vegetation. The prosthesis was carefully removed and replaced by a new bioprosthesis, though only small vegetation was observed on the removed prosthesis. Sudden blue toe 11 h after the operation and diminished pulse on right pedal artery suggested an acute arterial occlusion of a right lower extremity, requiring an emergency thrombectomy. Pathology diagnosed bacterial embolus with fresh thrombus that was considered apart from the prosthesis at the time of operation.
4.Parent Artery Complex Coil Protection for Side-Branched Wide-Neck Aneurysms
Keisuke SATO ; Hiroshi AOKI ; Shinya JINGUJI ; Hiroki SETO ; Tsutomu KOBAYASHI
Neurointervention 2022;17(2):115-120
This study aimed to validate the usefulness of parent artery complex coil protection for the treatment of wide-neck, side-branched, and ruptured aneurysms. A microcatheter was first introduced into the aneurysmal sac, and another microcatheter was introduced into the parent artery or near the orifice of the branch artery. A framing coil was deployed partially from the first microcatheter, and a protection coil was deployed from the second microcatheter to prevent protrusion of the first framing coil to the parent artery and side branches. After the first framing coil insertion, the protection coil was withdrawn to confirm the stability of the framing coil and blood flow. The procedures with this technique were successful for 3 patients. Parent artery complex coil protection can be an effective and safe coil embolization technique for the preservation of parent and side branch arteries and an alternative method for emergent ruptured cases.
5.How should we treat acute kidney injury caused by renal congestion?
Masanori ABE ; Seiichiro HEMMI ; Hiroki KOBAYASHI
Kidney Research and Clinical Practice 2023;42(4):415-430
Decreased kidney function is associated with increased risk of cardiovascular events and mortality, and heart failure (HF) is a wellknown risk factor for renal dysfunction. Acute kidney injury (AKI) in patients with HF often is attributed to prerenal factors, such as renal hypoperfusion and ischemia as a result of decreased cardiac output. Another such factor is reduction of absolute or relative circulating blood volume, with the decrease in renal blood flow leading to renal hypoxia followed by a decrease in the glomerular filtration rate. However, renal congestion is increasingly being recognized as a potential cause of AKI in patients with HF. Increased central venous pressure and renal venous pressure lead to increased renal interstitial hydrostatic pressure and a reduction of the glomerular filtration rate. Both decreased kidney function and renal congestion have been shown to be important prognostic factors of HF, and adequate control of congestion is important for improving kidney function. Loop and thiazide diuretics are recommended as standard therapies to reduce volume overload. However, these agents are associated with worsening renal function even though they are effective for improving congestive symptoms. There is growing interest in tolvaptan, which can improve renal congestion by increasing excretion of free water and decreasing the required dose of loop diuretic, thereby improving kidney function. This review summarizes renal hemodynamics, the pathogenesis of AKI due to renal ischemia and renal congestion, and diagnosis and treatment options for renal congestion.
6.Gender differences in preferences for mentoring styles and topics in academic medicine in Japan
Hiroki Mishina ; Ken Sakushima ; Kenei Sada ; Junji Koizumi ; Takashi Sugioka ; Naoto Kobayashi ; Masaharu Nishimura ; Junichiro Mori ; Hirofumi Makino ; Mitchell D Feldman ; Shunichi Fukuhara
Medical Education 2014;45(1):1-7
Objective: To evaluate gender differences in mentee’s preference for mentoring styles and topics in academic medicine in Japan.
Methods: We conducted a cross-sectional questionnaire survey of mentees at 6 graduate schools of medicine in Japan from December 2011 through January 2012. The study participants were 1700 Japanese-speaking graduate students and postdoctoral fellows. The primary outcome was the percentage of respondents who desired to be mentored with a particular style or topic.
Results: A total of 676 (227 women) mentees responded to the survey. Women were less likely than men to prefer a hierarchical mentoring relationship (men, 82%; women, 71%; p=0.001) but were more likely to desire a mentor for career consultation (men, 51%; women, 64%; p=0.001). Women were more likely than men to want guidance in developing a research portfolio (men, 85%; women, 90%; p=0.04), in computer skills/statistical skills (men, 68%; women, 81%; p=0.001), and in long-term career planning (men, 38%; women, 50%; p=0.003).
Conclusion: Women mentees in Japan express different preferences for mentoring styles and topics from men. Mentors in Japan must take these differences into consideration.
7.Analysis and Avoidance of Errors in Insulin Administration by Means of Quality Control (QC) Methods
Atsushi MIURA ; Fumi AOKI ; Hiroki MOMOI ; Kunimichi YANAGISAWA ; Keiko OOI ; Masaaki OOHASHI ; Reiko TAKEUCHI ; Yumiko KOBAYASHI ; Yumi SASAKI ; Teruaki OOKURA ; Osamu ATOBE
Journal of the Japanese Association of Rural Medicine 2008;57(5):719-725
The Saku Central Hospital classified muscular relaxants, potassium products and the like as “high-risk medicines”, but when it came to insulin, did not take any standardized measure against it to prevent accidents. Having organized a team of personnel from a wide variety of job, our hospital has recently carried out a campaign for improvements in medical care. With pharmacists playing a leading role, we grappled with measures for the prevention of errors in the administration of insulin using quality control (QC) methods. As a consequence, the campaign served to decrease the number of medical mistakes. As there still occur many incidents involving medication, the role played in risk management by pharmacists remains significant. In future, pharmacists will hopefully play a constructive role in risk management to prevent medical incidents involving medical supplies. That said, a campaign for improvements inmedical care through the practical use of QC methods seems likely to bring about favorable results.
Role
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Quality Control
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Analysis
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Avoidance
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ERROR
8.The Blended Teaching with Information and Communication Technology-based Learning before Classes and Simulated Clinical Problem-solving Training for the First-year Nursing Students
Hiroki NAMIKAWA ; Yasuhiko TAKEMOTO ; Tomomi TAKESHIGE ; Sachiko OKU ; Ayako MAKUUCHI ; Kazuo FUKUMOTO ; Masanori KOBAYASHI ; Shigeki KINUHATA ; Hiromitsu TOYODA ; Noriko KAMATA ; Yoshihiro TOCHINO ; Mina MORIMURA ; Taichi SHUTO
An Official Journal of the Japan Primary Care Association 2017;40(4):192-194
9.Clinical study on the prevention of recurrent tonshillitis by acupuncture (III)
Keishi YOSHIKAWA ; Kazushi NISHIJO ; Kazuhiro YAZAWA ; Hidetoshi MORI ; Tomomi SAKAI ; Akihiro OGATA ; Kazuo SASAKI ; Toshikazu SHIMA ; Hiroki SUGA ; Mikio NAKAMURA ; Shuichi KATAI ; Katsumi KURIHARA ; Takeshi TOMIYASU ; Masahiro KIMURA ; Takanori KAWANO ; Koki KOBAYASHI ; Koichi WADA ; Harumi TAKETANI ; Akemi YAMAMOTO
Journal of the Japan Society of Acupuncture and Moxibustion 1984;34(1):15-22
We have conducted acupuncture treatment for prevening the relapse of recurrent tonsillitis. We previously noted the effectiveness of this treatment in 121 of 239 patients treated in 1980, especially in elementary school children. In the present study, we compared the annual days of absence from school and the body dimensions of children with tonsillitis given acupuncture treatment with those having tonsillar hypertrophy chosen by a school study, although there is a question on the latter's propriety as a control group in a strict sense, in order to investigate the degree of spontaneous healing included in the preventive effects of acupuncture treatment on the relapse of recurrent tonsillitis.
By May 1983, our reseach was completed in 22 children with tonsillitis given acupuncture treatment and 19 with tonsillar hypertrophy not given such therapy. In children with tonsillitis given acupuncture treatment, the average annual days of absence from school before treatment was 14.0, which was more than that for all children in the S elementary school, and that in the year after treatment was 6.5, approximating that for all children in the school. In children with tonsillar hypertrophy not given acupuncture treatment, the average number of days of absence was close to that for all children in the S elementary school in both years.
Among 14 children with tonsillitis given acupuncture treatment, lower values of height and weight were noted in eight and 12 children, respectively, at the beginning of treatment, as compared with the national averages. The body dimensions of children with tonsillar hypertrophy not given acupuncture treatment were similar to the national averages. Of 14 children with tonsillitis given acupuncture treatment, an increase to a value exceeding the national average was observed with both the height and weight in six children, the height in two and the weight in one within the year after treatment.
The above results show that children with tonsillitis have a problem from the educational and developmental standpoint, even if they do not have a focal tonsil. We think that acupuncture treatment is worth attempting prior to tonsillectomy, although it is not so surely effective as tonsillectomy, when the severity of operative stress on the living body due to tonsillectomy and the burden of medical expenses and the load on the patient's family caused by hospitalization are taken into consideration.
10.Assessment of the Relationship between Pelvic Tilt and the Sacro-Femoral-Pubic Angle in Middle-Aged and Elderly Asian Individuals.
Takanori KITAGAWA ; Yoichi IIZUKA ; Hiroki KOBAYASHI ; Tokue MIEDA ; Daisuke TSUNODA ; Atsushi YAMAMOTO ; Tsuyoshi TAJIKA ; Haku IIZUKA ; Kenji TAKAGISHI
Asian Spine Journal 2017;11(6):975-980
STUDY DESIGN: Cross-sectional study. PURPOSE: The purpose of this study was to evaluate the correlation between pelvic tilt (PT) and the sacro-femoral-pubic (SFP) angle, which is easier to identify than PT, in middle-aged and elderly Asian subjects from the general population. OVERVIEW OF LITERATURE: Measuring PT is important in the diagnosis and treatment of adult spinal deformity. However, identifying femoral heads, which are necessary to determine PT, using sagittal radiographs is often difficult. METHODS: Standing coronal and sagittal pelvic radiographs of individuals aged more than 50 years were taken during a local medical examination. The subjects were divided into female, male, and total groups at the time of evaluation. Linear regression analysis was performed to investigate the relationship between PT and the SFP angle, which were obtained from the X-rays. RESULTS: The present study included 291 subjects. There were no statistically significant differences between the left and right SFP angles, and there was gender difference regarding the SFP angle. However, a gender difference was observed regarding PT. The correlation between PT and the SFP angle was substantiated in each group. Pearson's correlation coefficients between PT and the SFP angle in the total, female, and male groups were 0.696, 0.853, and 0.619, respectively. In the linear regression analysis, PT was calculated as follows: PT=60.1−0.77×(SFP angle) in the total group, PT=62.8−0.80×(SFP angle) in the female group, and PT=51.5−0.64×(SFP angle) in the male group. CONCLUSIONS: A significant correlation between PT and the SFP angle was observed in middle-aged and elderly Asian subjects from the general population.
Adult
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Aged*
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Asian Continental Ancestry Group*
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Congenital Abnormalities
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Cross-Sectional Studies
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Diagnosis
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Female
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Head
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Humans
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Linear Models
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Male
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Pelvis
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Spine