1.Lumbar Spinal Stenosis Due to a Large Calcified Mass in the Ligamentum Flavum.
Shoji SEKI ; Yoshiharu KAWAGUCHI ; Hirokazu ISHIHARA ; Takeshi OYA ; Tomoatsu KIMURA
Asian Spine Journal 2013;7(3):236-241
We describe a rare case of lumbar spinal stenosis due to a large calcified mass in the ligamentum flavum. This patient presented with a 12-month history of severe right leg pain and intermittent claudication. A computed tomography scan was performed, revealing a large calcified mass on the ligamentum flavum at the right-hand side of the lumbar spinal canal. We performed a laminotomy at the L4/5 level with resection of the calcified mass from the ligamentum flavum. The findings of various analyses suggested that the calcified mass consisted mostly of Ca3(PO4)2 and calcium phosphate intermixed with protein and water. The calcified mass in the ligamentum flavum was causing lumbar spinal stenosis. Surgical decompression by resection of the mass was effective in this patient. The calcified material was composed mainly of elements derived from calcium phosphate. Degenerative changes in the ligamentum flavum of the lumbar spine may have been involved in the production of this calcified mass.
Calcium
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Calcium Phosphates
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Decompression, Surgical
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Humans
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Intermittent Claudication
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Laminectomy
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Leg
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Ligamentum Flavum
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Spinal Canal
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Spinal Stenosis
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Spine
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Water
2.En Bloc Spondylectomy for Spinal Metastases: Detailed Oncological Outcomes at a Minimum of 2 Years after Surgery
Masayuki OHASHI ; Toru HIRANO ; Kei WATANABE ; Kazuhiro HASEGAWA ; Takui ITO ; Keiichi KATSUMI ; Hirokazu SHOJI ; Tatsuki MIZOUCHI ; Ikuko TAKAHASHI ; Takao HOMMA ; Naoto ENDO
Asian Spine Journal 2019;13(2):296-304
STUDY DESIGN: Retrospective case series. PURPOSE: To investigate the oncological outcomes, including distant relapse, after en bloc spondylectomy (EBS) for spinal metastases in patients with a minimum of 2-year follow-up. OVERVIEW OF LITERATURE: Although EBS has been reported to be locally curative and extend survival in select patients with spinal metastases, detailed reports regarding the control of distant relapse after EBS are lacking. METHODS: We conducted a retrospective review of 18 consecutive patients (median age at EBS, 62 years; range, 40–77 years) who underwent EBS for spinal metastases between 1991 and 2015. The primary cancer sites included the kidney (n=7), thyroid (n=4), liver (n=3), and other locations (n=4). Survival rates were estimated using the Kaplan–Meier method, and groups were compared using the log-rank method. RESULTS: The median operative time and intraoperative blood loss were 767.5 minutes and 2,375 g, respectively. Twelve patients (66.7%) experienced perioperative complications. Five patients (27.8%) experienced local recurrence of the tumor at a median of 12.5 months after EBS, four of which had a positive resection margin status. Thirteen patients (72.2%) experienced distant relapse at a median of 21 months after EBS. The estimated median survival period after distant relapse was 20 months (95% confidence interval, 0.71–39.29 months). No association was found between resection margin status and distant relapse. Overall, the 2-year, 5-year, and 10-year survival rates after EBS were 72.2%, 48.8%, and 27.1%, respectively. Importantly, the era in which EBS was performed did not impact the oncological outcomes. CONCLUSIONS: Our results suggest that EBS by itself, even if margin-free, cannot prevent further dissemination, which occurred in >70% of patients at a median of 21 months after EBS. These results should be considered and conveyed to patients for clinical decision-making.
Clinical Decision-Making
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Follow-Up Studies
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Humans
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Kidney
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Liver
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Methods
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Neoplasm Metastasis
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Operative Time
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Recurrence
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Retrospective Studies
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Spine
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Survival Rate
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Thyroid Gland