1.Two Cases of Y-Grafting Using Terminal Branches of the Left Internal Thoracic Artery for Coronary Artery Bypass
Hirofumi Nakagawa ; Tatsuya Nakao ; Norifumi Shigemoto
Japanese Journal of Cardiovascular Surgery 2008;37(6):368-371
The excellent long term-patency rates achieved using the internal thoracic arteries (ITAs) have expanded the variety of graft arrangements of these conduits for multivessel coronary revascularization. We encountered 2 patients who underwent multivessel coronary artery bypass, by using these terminal branches of the left ITA effectively. In both patients, LITAs were taken down using the skeletonization technique with a harmonic scalpel. One patient had 2 grafts using the off-pump technique with the Y-composite grafts constructed by the main LITA trunk and LITA terminal branch, which were anastomosed with the left anterior descending branch (LAD) and diagonal branch (D1), respectively. The other patient had 6 grafts under on-pump cardiac arrest, including the natural LITA terminal branches which were anastomosed with the LAD and D1. Postoperative multidetector computed tomography (MDCT) revealed excellent long-term patent grafts in both patients. In conclusion, the terminal branches of the ITA, if of suitable size and length, could be used effectively to construct a Y-anastomosis for the coronary arteries, when consideration for the size of the target coronaries and native-coronary blood flow competition.
2.Risk assessment of re-emerging Plasmodium falciparum on Ishigaki Island using a stochastic transmission model
Yuuki Nakagawa ; Masao Ueki ; Kaoru Fueda ; Hiroshi Ohmae ; Hirofumi Ishikawa
Tropical Medicine and Health 2009;37(3):97-107
On Ishigaki Island, Plasmodium falciparum and Plasmodium vivax epidemics occurred in 1945-1946 and were successfully suppressed. The epidemic re-emerged in 1949 because many settlers immigrated to the former endemic areas, but it terminated in 1961. The present study aimed at predicting an outbreak of a new epidemic based on the situation in which P. falciparum malaria patients stay on Ishigaki Island and also examined the re-emergence of the P. falciparum epidemic in 1951-1960 to determine the reliability of the model.
A stochastic transmission model of P. falciparum was constructed to detect a small number of infected persons. The seasonal fluctuation of the Anopheles minimus population obtained by observational data and meteorological data through statistical processing was introduced into the model.
Simulations were carried out to predict the risk of a new epidemic with scenarios in which the attribute of index patient, visiting season, and reduced inoculation rates of An. minimus were assumed. When an infected person visited the island in summer, a small number of patients with primary infections derived from the index patient appeared for all 1,000-iterations. On the other hand, when an infected person visited the island in winter, few or no patients with primary infections appeared for any of the 1,000-iterations because of the low mosquito density. In realistic conditions, the simulation results showed that there was little possibility of the occurrence of P. falciparum infection.
3.EFFECT OF TWO PASSIVE STRETCHING METHODS FOR TRICEPS SURAE ON DORSIFLEXION OF ANKLE JOINT
TAKAYUKI INAMI ; TAKUYA SHIMIZU ; HIROFUMI MIYAGAWA ; MASAYUKI INOUE ; TAKEO NAKAGAWA ; FUJIMARU TAKAYANAGI ; SHIGEO NIWA
Japanese Journal of Physical Fitness and Sports Medicine 2010;59(5):549-554
Stretching for the triceps surae muscle in the knee flexed position (medical stretching: MS) and knee extended position (static stretching: SS) were performed and the effect on the dorsiflexion angle of the ankle joint was examined. Five elderly females were selected as subjects. We measured the maximal dorsiflexion angle of the ankle joint in the following leg positions: (1) the maximal dorsiflexion angle in the extended knee position (EDF angle) and (2) the maximal dorsiflexion angle in the 90°flexed-knee position (FDF angle). There was a significant increase in the maximal dorsiflexion angle after MS and SS were carried out (p<0.01), but there was no significant difference between MS and SS. It was concluded that MS for triceps surae is equally effective as SS in increasing the maximal dorsiflexion angle of the ankle joint.
4.Bentall Procedure for Aortic Root Dilatation in a Patient with Turner Syndrome
Hirofumi Nakagawa ; Akihiro Nabuchi ; Masahiro Terada ; Takuya Miyazaki ; Hiroshi Okuyama ; Masahiro Endo
Japanese Journal of Cardiovascular Surgery 2016;45(1):21-25
A 30-year-old woman who had no specific symptom was diagnosed with Turner syndrome at the age of 6 years. Subsequently, she was followed up at a hospital. However, she stopped going to the hospital when she was 18 years old. At 30 years of age, she underwent examinations involving echocardiography and enhanced chest CT at a hospital, which revealed severe aortic valve regurgitation and extreme dilatation of the aortic root. We performed the Bentall procedure through a median sternotomy following which she had an uncomplicated postoperative course. Aortic root enlargement increases the risk of aortic dissection in patients with Turner syndrome. However, no aortic events occurred before the surgery in this case. We considered the reason was related to the mosaic karyotype of this case.
5.A Life-Threatening Case of Infective Endocarditis Complicated by Destruction of the Aortic Valve and Embolism of the Left Anterior Descending Coronary Artery
Hirohito TERADA ; Taishi KAWAHATA ; Keisuke NAKAMURA ; Hirofumi NAKAGAWA ; Hiroshi OKUYAMA ; Akihiro NABUCHI
Japanese Journal of Cardiovascular Surgery 2023;52(1):18-23
A 39-year-old man with fever and dyspnea from 3 days earlier was taken to the emergency room. He was diagnosed with infective endocarditis because echocardiography showed a mobile 10 mm-sized vegetation on the aortic valve and severe aortic regurgitation. Acute coronary syndrome was negative because the tests at the first visit did not show an increase in myocardial deviation enzymes or a decrease in wall motion. However, his hemodynamics deteriorated during the same day, so he underwent emergency surgery. The left and right leaflets and the right aortic annulus were highly destroyed, and the aortic annulus was reconstructed with his pericardium and the valve was replaced by a mechanical valve. After declamping of the aorta, the wall motion of the left ventricle was extremely reduced, and the cardiopulmonary bypass(CPB) was not able to be withdrawn. Since the left anterior descending (LAD) coronary artery may have been occluded by vegetation, we added bypass surgery to the LAD under cardiac arrest using a saphenous vein graft. After the bypass surgery, the wall motion of the left ventricle improved, and we were able to withdraw the CPB. Though he developed a cerebral infarction as a complication and required long-term rehabilitation, he was able to be discharged from the hospital 74 days after the operation. We evaluated the coronary arteries after his discharge and found an occlusion that was thought to be due to vegetation scattered in the LAD. No preoperative coronary artery evaluation was performed, however, the graft was anastomosed to the distal side of the LAD occlusion. Currently, 3 years and 2 months have passed and the infection has not recurred.
6.Development of a Patient Registry System for Specialized Palliative Care Quality Assessment Using Patient-reported Outcomes: A Multicenter Pilot Study
Hideyuki HIRAYAMA ; Eriko SATOMI ; Yoshiyuki KIZAWA ; Mayuko MIYAZAKI ; Keita TAGAMI ; Ryuichi SEKINE ; Kozue SUZUKI ; Nobuyuki YOTANI ; Koji SUGANO ; Hirofumi ABO ; Meidai SAKASHITA ; Kazuki SATO ; Sari NAKAGAWA ; Yoko NAKAZAWA ; Jun HAMANO ; Mitsunori MIYASHITA
Palliative Care Research 2022;17(4):171-180
Objective: This study aimed to investigate the feasibility of a patient registry system for assessing PCT (palliative care team) by PRO (Patient-reported outcome) in Japan. Methods: We operated a patient registry system with electronic data collection at eight hospitals in 2021 in Japan. We consecutively included newly referred patients for a month and followed up with them for a month. IPOS or ESAS obtained as PRO at the start of the intervention, three days later, and every week after. The primary endpoint was the response rate to the symptom rating scale by patients and providers. Results: 318 patients were enrolled. The patient response rate was 59.1% at intervention and 37.0% after intervention, and the medical provider response rate was 98.4% at intervention and 70.3% after intervention. Interviews with PCT members indicated that participants required support to input PRO responses required support and paper questionnaire was better and that managing the survey date and overall management was burdensome. Discussion: Although only about half of the patients were able to respond to the PRO, this was the same level as in previous studies. The system and its operation method have many problems. We found that improvements such as reducing items and making the patient interviews paper-based are necessary to expand the system nationwide.