This paper was primarily concerned with the effect of acupuncture treatment on blood pressure and heart rate.
Systolic blood pressure, diastolic blood pressure and heart rate were measured before and after acupuncture treatment in one hundred new outpatients in the clinic of Research Institute of Oriental Medicine, Kinki University. Fifty patients were finally recognized to be worthy of the present analysis. Application of “t” test was done in these 50 patients and 18 normal persons.
In a comparison of acupunctured group with control group, systolic blood pressure and diastolic blood pressure showed a statistically significant rise, but heart rate did not.
According to the effect on blood pressure, acupuncture practitioners were divided into three groups. Among these groups, heart rate showed a statistically insignificant change.
These results suggest that the reaction pathway of the biological effect of acupuncture treatment on blood pressure is different from that on heart rate. It is also suggested that the therapeutic effect of acupuncture treatment is highly influenced by the technique of acupuncture practitioners.

A 14-year-old girl with atopic dermatitis was treated by Kampo-medicine. Both her clinical picture and laboratory findings were evidently consistent with those of atopic dermatitis. Skin Iesions were prominent on her forehead, upper eye lides, cervical region and cubital regions. The percentage of eosinophilic leucocyte was 9% before the therapy of Reikeijutsukan-To and was 1% after the therapy. The value of IgE (<500) was 3, 091 before the therapy and was 3, 567 after that. Radioallergosorbent test (RAST) was abnormal and essentially not changed before and after the therapy. The mechanism of the therapeutic effect of Reikeijutsukan-To was briefly discussed from the stand point of “whole body pathology”

A 52-year-old housewife with chalazion was non-operatively treated by Kampo-medicine.
There were three chalazions on her right under eyelid and many infarcts of tarsal gland on her bilateral eyelids. Two of the three chalazions were successfully treated and the residual one became clinically non-troublesome. A large infarct of tarsal gland on her left upper eyelid disappeared through the process of conjuctival polyp formation, being well recorded photo graphically. Decoctions of derivatives of Saikokeishi-To were used for the therapy.
The therapeutic mechanism of the clinical picture was briefly considered from both the stand point of “cell pathology” and that of “whole body pathology”.

　　The first patient was a 33-year-old man with a history of fatty liver disease. Dynamic computerized tomography of a lesion in liver segment IV showed faint staining in the arterial phase and high signal intensity in the portal venous and equilibrium phases. The second patient was a 57-year-old woman also with a history of fatty liver disease. Magnetic resonance imaging (MRI) of a lesion in segment II in T1 out of phase revealed geographic morphology and high signal intensity. Furthermore, Gd-EOB-DTPA-enhanced MRI showed accumulation in the lesion in the hepatobiliary phase. In both cases, an aberrant left gastric vein and focal fat sparing area was diagnosed. Venous inflow to the liver other than via the portal vein may cause fatty degeneration of liver parenchymal cells or focal fat sparing due to imbalanced intrahepatic blood flow. In the present cases, imaging revealed a focal fat sparing area with an aberrant left gastric vein. Focal fat sparing area with aberrant inflow vessel identified in the background of fatty liver does not require biopsy or surgery. Therefore, further detailed evaluation of such images is warranted.

This paper reported a patient of a tendency to somnolence well treated with “Sansonin-to”. The patient was a 52-year-old house wife, small and lean, who always felt tired and had an intense desire and tendency to sleep in spite of a lot of sleep in nights. Her abdominal tonus was rather soft, and pulsation above the navel and tenderness besides the navel were evidently noticed.
At first, Toki-syakuyaku-san-ka-bushi (Dang-Gui-Shao-Yao-San-Jia-Fu-Zi) and Sansonin-to (Suan-Zao-Ren-Tang) were prescribed alternately every fourth day for one month, and afterwards, Sansonin-to was given predominantly, being Toki-syakuyaku-san concurrently. After about two months, the tendency to somnolence was completely improved.
In view of the effective results, already reported by us, of two insomniac patients with Sansonin-to, the decoction, Sansonin-to, can be inferred to have an effective function to both insomnia and somnolence. Regardless of the procedure of “roasting or no-roasting” the seed of Zizyphus jujuba Mill before boiling and making a medical decoction, some essential compositions of the seed might be necessary to be extracted into the decoction.

A 48-year-old man, suspected of erythema annulare centrifugum, was treated by Kampo-medicine. His clinical picture and findings were evidently consistent with those of erythema annulare centrifugum. Skin lesions, chiefly consisted of erythema with a little of exfoliation, were noticed both on the upper abdomen and on the bilateral lumbar regions.
Decoctions of Dai-saiko-to (Da-Chai-Hu-Tang) were mainly used for the treatment, concurrently with Keishi-bukuryo-gan (Gui-Zhi-Fu-Ling-Wan). Lumbar eruption comp letely disappeared after one month of the treatment and abdominal one also after four months without any trace of lesions.
The therapeutic mechanism of the skin lesions was briefly considered from both the stand point of “cell pathology” and that of “whole body pathology”.

A 69-year-old housewife with chronic eczema was treated by Kampo-medicine. For about 20 years, she had suffered from episodes of general eruptions every summer. At our outpatient clinic, skin lesions, chiefly consisted of papules with erosions, were noticed on bilateral external surface of the nose, the back of right hand and the back of the neck.
At first, decoctions of Keishibukuryo-gan-ka-Daio was prescribed for one month, and afterwards, Keishibukuryo-gan-ka-Daio Yokuinin for the rest. The lesions was completely improved after two or five months of the treatment, and the other skin lesions appeared on bilateral forearms, disappearing also after two or three months of the same design of the treatment. After the therapy by Kampo-medicine, no skin lesions were noticed at least for more than two years.
The therapeutic mechanism of the skin lesions was briefly discussed from both the stand point of “Cell pathology” and that of “Whole body pathology”.

A 19-year-old girl with atopic dermatitis was treated by Kampo-medicine. At our outpatient clinic, her skin lesions were especially prominent on her face and cervical region, although noticed also on chest, abdomen, cubital and popliteal regions.
At first, decoctions of Byakko-ka-Ninzin-To was prescribed in ordinary quantities of composite materials (crude drugs), and afterwards, the crude drug (Coptis japonica, Makino) was added. To improve facial flush and thirst, quantities of Coptis japonica and Gypsum were gradually increased. After 25 weeks of this therapy, the skin lesions almost disappeared, and afterwards, no remedy was needed at least for more than three years.
The therapeutic mechanism of the skin lesions was briefly discussed from both the stand point of “Cell pathology” and that of “Whole boby pathology”.

Background : Both low-frequency repetitive transcranial magnetic stimulation (rTMS) and intensive occupational therapy (OT) have been recently reported to be clinically beneficial for post-stroke patients with upper limb hemiparesis. We have already reported that the function of the paralyzed upper limb in the post-stroke hemiplegic patients was improved after a 15-day hospitalization protocol, named NEURO-15. In this present study, we investigated whether two courses (2X) of NEURO-15 were superior to a single one in therapeutic efficacy. Methods: During NEURO-15, each patient was scheduled to receive 21 treatment sessions of 20-min low-frequency rTMS followed by 120-min intensive OT daily. Low-frequency pulses of 1 Hz were applied to the motor cortex of the nonlesional hemisphere. Fugl-Meyer Assessment (FMA), log performance time of the Wolf Motor Function Test (WMFT) and modified Ashworth Scale (MAS) were evaluated on the days of admission and discharge. The first NEURO-15 was given to 16 apoplectic hemiplegic patients whose Brunnstrom Recovery Stage in their fingers ranged from IV to V. After an average of 13.6 months, the second NEURO-15 was administered to all 16 patients. Results : The 2X protocol was completed by all patients without any adverse effects. After the first course of NEURO-15, all patients showed improvement in their paralyzed upper limb function ; improvements which remained until the second NEURO-15 course. The second NEURO-15 course yielded even further improvement in the paralyzed upper limb function. Conclusions : Our proposed combination treatment is a safe, feasible, and clinically useful neurorehabilitative intervention for post-stroke patients with upper limb hemiparesis when administered as both a single application or as a 2X protocol. The effectiveness of the 2X protocol or even more frequent application of NEURO-15 courses needs to be further explored.