1.Comparison of the prognostic validity of three indicators for evaluation of traumatic severity in children
Hieu Quang Tran ; N. Bello ; P.J. Adnet ; C. Marescal ; J Desbordes ; P. Goldstein ; P. Boiteaux
Journal of Surgery 2007;57(1):61-67
Background: The leading cause of death in under 16 years old children is by accident. A correct assessment for traumatic severity will help clinicians having an appropriate treatment and improving pediatric mortality. Objectives: To assess the prognostic validity of indicators Pediatric Trauma Score (PTS), Coma Glassgow Scale (CGS) and Revised Trauma Score (RTS) during short term for pediatric trauma. Subjects and method: Using the 3 indicators to evaluate traumatic severity in 92 patients (34 female, 58 male) at the age of 1 month olds to 15 year olds, treated in emergency unit from January, 1993 to May, 1994 in CHRU de Lille. Results: There are 2 main accidents as traffic accident (70%) and fall (25%). Traumatic mechanisms are closed trauma (69%), cranial trauma (80%), orthopedic trauma (33%), chest trauma (18%), abdominal trauma (21%). CGS indicator is more sensitive but less specific than the other two indicators. Its predictive validity is significantly higher than the validity of PTS or RTS. The probability of hospitalized patients with CGS<6, when discharging with complication is 100%. Conclusion: CGS indicator and improvement of it is appropriate to children. It is the most suitable in short-term predicting the possibility of complications. PTS and RTS indicators seem to be better on evaluating preliminary traumatic severity.
Wounds and Injuries/diagnosis
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Child
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2.Study on the effective control of postpreal blood glucose of resistant starch cakes in patients with type 2 diabetes
Huu Dung TRAN ; Quang Hung LE ; Bao Dung VO ; Hoang Vu NGUYEN ; Thanh Bao Yen LUONG ; That Hy TON ; Phuoc Hieu DOAN ; Thi Bich Hien PHAM ; Huu Tien NGUYEN ; Hai Thuy NGUYEN
Hue Journal of Medicine and Pharmacy 2023;13(7):52-58
Background: This study was conducted on 93 volunteers with type 2 diabetes to investigate the ability of acetylated wheat starch cake containing 32.1% resistant starch to control postprandial blood glucose levels. Material and methods: The study was designed using a crossover, double-blind trial method. During each testing day, after a minimum of 12 hours of overnight fasting, each participant consumed two identical cakes containing either 80 g of acetylated wheat starch or 80 g natural wheat starch with 330ml of water within 15 minutes. Blood glucose levels were measured at baseline, 60 mins (G1), and 120 mins (G2) after ingestion. The predictive value of factors that contribute to the ability of resistant starch to control postprandial blood glucose was determined by the area under the receiver operating characteristic (ROC) curve based on the combined effect of the cake weight-to-BMI ratio (g/m²BMI) and HbA1c. Results: 60 mins and 120 mins postprandial capillary glucose levels after consuming acetylated wheat starch cake (10.4 ± 1.2 và 9.2 ± 1.2 mmol/L, respectively) were significantly lower compared with natural wheat starch cake (13.3 ± 1.8 và 11.2 ± 1.8 mmol/L, respectively) (p < 0.05). For good control of postprandial blood glucose levels, a maximum of 80 g of acetylated wheat starch can be used per serving for patients with type 2 diabetes with HbA1c ≤ 7.25 without blood glucose-lowering medication is required. Conclusion: acetylated wheat starch has better ontroled of postprandial blood glucose compared with natural wheat starch in patients with type 2 diabetes. This is very suitable in the processing of diets including resistant starch for patients with type 2 diabetes for the purpose of both supporting treatment and improving quality of life.