1.The cerebral protective effect of a medicinal formula in mice with ischemia/reperfusion induced brain injuries
Journal of Medicinal Materials - Hanoi 2005;10(3):96-98
The experimental trials was conducted on Swiss white mice of 7 weeks of age, both sexes, and weight of 20-22g. Results: SOD activity in mice with ischemia/reperfusion was significantly statistical lower than those in the control group, p<0.05. In the group treated by “activating the blood and clearing the obstruction” formula with dose of 200 mg/kg, SOD activity was lower than those in the research group (89.5%) and was 73.7% compared to control group. In the group treated by this formula with dose of 300 mg/kg, SOD content was still lower than those in the research group (96%) and was 79.5% compared to control group. In the group treated by the dose of 500 mg/kg, SOD activity was higher significantly than those in the research group (113.6%) and was 96% compared to control group. The result showed that with appropriate dose, this medicinal formula has antioxidant effects
Brain Injuries
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Mice
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Ischemia
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Reperfusion
2.The in vitro and in vitro antioxidant activities of the ethyl acetate extracted from Radix Polygoni multiflori
Journal of Medicinal Materials - Hanoi 2005;10(2):59-63
Radix Polygoni multiflori has been used Vietnamese traditional medicine for a long time. This paper presented the remarkable antioxidant effects of the AcOET extract from Radix Polygoni multiflori with evidences obtained from various antioxidant tests: inhibition of lipid peroxidation in cell hemogenates, of anion superoxide production, stimulation of SOD activity using Ransod kits. The extract protected the splenocytes from H20¬2- induced injuries and protected brain cells from oxidative stress caused by an ischemia/reperfusion course. These results suggested that application of Radix Polygoni multiflori as antioxidant agent will be beneficial in prevention and treatment of diseases of the elderly
Acetates
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Antioxidants
3.Efficacy of the traditional medication for treatment of the Hepatitis B (sirupe Hebovera) which support the production of antibody against surface antigen Hepatitis B (anti HBs) in the chronic HBsAg carriers
Journal of Medical and Pharmaceutical Information 2000;(4):19-21
In Vietnamese indigenous medicine, the leaves of Artocarpus tonkinensis A-chev are used for treatment of lumbago and myoasthenia. Our study finds the flavonoid fraction from leaves of Artocarpus tonkinensis A-chev, is a potential antioxidant agent - Kaemferol in the total flavonoid fraction and it has an inhibitory effect against the lipid peroxydation of liver
flavonoids
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Liver
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Plants, Medicinal
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Medicine, Traditional