No abstract available.
Hidradenitis Suppurativa* ; Hidradenitis* ; Humans ; Serratia marcescens* ; Serratia* ; Skin*

Hidradenitis suppurative is a chronic, refractory and recurrent dermatological disease. The disease should be managed by targeted surgical intervention on the basis of medical treatment. Currently, the surgical treatment methods include local treatments like incision and drainage, unroofing, laser therapy, intense pulsed light therapy, photodynamic therapy, as well as complete lesion resection such as skin-tissue saving excision with electrosurgical peeling and extended excision. The clearance range, therapeutic effect, postoperative complications, and recurrence risk vary among the different treatment methods. Local treatments cause less damage, but have high recurrence rates, and are mainly for mild to moderate hidradenitis suppurative patients. Complete lesion resections have relatively low recurrence rates, but may bring more surgical injuries, and postoperative reconstructions are needed, which are mainly for moderate to severe hidradenitis suppurative patients. In this article, the surgical treatment principles and various surgical treatment methods of hidradenitis suppurative are reviewed, to provide a reference for the diagnosis and treatment of this disease in clinical practice.
Humans ; Hidradenitis Suppurativa/complications* ; Hidradenitis/complications* ; Drainage ; Postoperative Complications ; Skin

Hidradenitis Suppurativa/therapy* ; Humans ; Singapore/epidemiology*

Hidradenitis suppurativa is a rare disorder that is characterized by recurrent chronic skin infections and the formation of sinus tracts and considerable scaring. A 37-year-old man presented with a hard posterior neck mass. Multiple pus-producing sinuses were detected in the skin covering the mass. MRI demonstrated an ill-defined, soft tissue mass with multiple variable sized cystic lesions. The soft tissue mass measured 12x10x4 cm in the subcutaneous fat layer, it contained multifocal cystic lesions that revealed higher signal intensity on both the T1- and T2-weighted images, as compared with the adjacent neck muscles. The mass was not enhanced on the post-contrast T1 weighted images. Some of the cystic lesions extended to the skin. The mass was removed surgically and confirmed to be hidradenitis suppurativa.
Adult ; Hidradenitis Suppurativa* ; Hidradenitis* ; Humans ; Magnetic Resonance Imaging ; Neck Muscles ; Neck* ; Skin ; Subcutaneous Fat

Hidradenitis suppurativa is a rare disease which represents a chronic suppurative and scarring process, affecting the apocrine glands due to persistent bacterial infection and apocrine dysfunction. We have experienced a case of hidradenitis suppurativa, 22-year-old female which involved both axillary region. Diagnosis was established by clinical characteristicsymptoms, histopathological findings and bacteriological examinations.
Apocrine Glands ; Bacterial Infections ; Cicatrix ; Diagnosis ; Female ; Hidradenitis Suppurativa* ; Hidradenitis* ; Humans ; Rare Diseases ; Young Adult

Hidradenitis Suppurativa (HS) is a chronic relapsing disease that involves the apocrine gland-bearing skin. It results in sinus tract formation, fibrosis and scarring. Many different treatments for HS have been reported, including topical and systemic antibiotics, intralesional steroids, systemic retinoids, hormonal therapies and immnunosuppressive agents, but they all have limited beneficial effects. Surgical treatments, including wide exteriorization with secondary intention, a skin graft and a flap can be effective treatments for recalcitrant HS. We present here the case of a 26-year-old man with recurred inguinal and axillary HS, and this was treated with secondary healing and a split thickness skin graft after exteriorization. Based on our experience, it is suggested that secondary healing and a split thickness skin graft after exteriorization are effective for recalcitrant HS with multiple interconnected tracts and abscesses.
Abscess ; Adult ; Anti-Bacterial Agents ; Cicatrix ; Fibrosis ; Hidradenitis ; Hidradenitis Suppurativa ; Humans ; Intention ; Retinoids ; Skin ; Steroids ; Transplants

Hidradenitis suppurativa is a chronic, relapsing suppurative disease of the apocrine sweat glands that principally affects the axillary and anogenital regions. The etiology of this disorder remains unknown. As conservative treatment usually does not prevent recurrence, surgical treatment is the method of choice, particularly for advanced case. We report a 25-year-old male patient who presented with a 7-year history of abscesses with foul-smelling discharge from his axilla. After failed medical therapy, he was referred for surgery. We performed a wide excision of the axilla with a split thickness skin graft after 1 week. The patient has been doing well, and there has been no relapse for about ayear after the operation.
Abscess ; Adult ; Axilla ; Hidradenitis ; Hidradenitis Suppurativa ; Humans ; Male ; Recurrence ; Skin ; Sweat Glands ; Transplants

Hidradenitis suppurativa (HS) is a disorder of the apocrine gland causing a chronic, recurrent and painful inflammation. It is a disabilitating condition and, though many therapeutic options are available, the response is often ineffective in most cases and patients can present many recurrences with physical and psychological sequelae. Recent data had shown increased interleukin (IL)-17 serum levels in patients with HS. Psoriasis is a chronic immune-mediated inflammatory disorder and new evidences have shown the role of Th17 cells in its pathogenesis and the therapeutic efficacy of anti-IL-17 antibodies. We present a case of a patient suffering from psoriasis and HS successfully treated with anti-IL-17 antibodies for both conditions. This is the first case report of HS treated with secukinumab.
Antibodies ; Apocrine Glands ; Hidradenitis Suppurativa* ; Hidradenitis* ; Humans ; Inflammation ; Interleukin-17 ; Interleukins ; Psoriasis* ; Recurrence ; Th17 Cells

PURPOSE: Hidradenitis suppurativa is a chronic suppurative and cicatricial inflammatory disease involving apocrine gland- bearing areas including the axilla, groin, and anogenital regions. Recurrence after surgery is not rare, and there is much debate about operative methods. This study analyzed the clinical characteristics and the relationship between different surgical methods and recurrences of perianal hidradenitis suppurativa. METHODS: A retrospective study of 20 patients with perianal hidradenitis suppurativa was done. The clinical characteristics were examined. The patients were divided into several groups (acute, chronic regional, chronic extensive) according to lesion status; then, different operative methods and recurrence rates were compared. RESULTS: All of the patients were male smokers. The mean age of onset was 28.4 years. The mean duration of disease was 10 years. The total number of operations, including incision and drainage, was 29 cases. Only 4 patients were overweight or obese. The most common symptom was pus discharge (52%). The recurrence rate after final surgery was 30.0%. After incision and drainage in the acute group, 7 of 8 cases (87.5%) recurred. In the chronic regional group, 5 of 9 cases (55.6%) experienced recurrence after excision and primary repair. After excision and healing by secondary intention, 1 of 7 cases (14.3%) had recurrence. In the case of one unroofing and marsupialization, there was no recurrence. In the chronic extensive group, 1 recurrence was noted in 4 unroofings and marsupializations. CONCLUSIONS: In the case of abscess, proper incision and drainage is needed, but further definitive surgery must be done. In the case of chronic disease, if the lesions are regional, excision and healing by secondary intention is more ideal for decreasing the recurrence rate. If the lesions are extensive, unroofing and marsupialization is recom-mended.
Abscess ; Age of Onset ; Axilla ; Chronic Disease ; Drainage ; Groin ; Hidradenitis Suppurativa* ; Hidradenitis* ; Humans ; Intention ; Male ; Overweight ; Recurrence ; Retrospective Studies ; Suppuration

Hidradenitis suppurativa is a chronic inflammatory disease that originate in the apocrine glands of the skin, It results in fibrosis, sinus track formation, and scarring. Rarely it is complicated by squamous cell carcinoma arisihg from hidradenitis suppurativa were reported in the literature. We present a patient who suffered over 20 years from persistent, extensive hidradenitis suppurativa and who developed squamous cell carcinoma at the perianal area. During the 18 month follow-up period, no evidence of recurrence nor metastasis was found.
Apocrine Glands ; Carcinoma, Squamous Cell ; Cicatrix ; Fibrosis ; Follow-Up Studies ; Hidradenitis Suppurativa* ; Hidradenitis* ; Humans ; Neoplasm Metastasis ; Recurrence ; Skin