1.Factors Related to the Occurrence of Homeboundness Among Community-dwelling Frail Elderly Individuals
Shuichi WAKAYAMA ; Yoshihiko FUJITA ; Kazushi HOTTA ; Keisuke FUJII ; Hideki SHIRAISHI ; Naoki MAKI ; Satoko NAKANO ; Yu TAKATA ; Hisako YANAGI
An Official Journal of the Japan Primary Care Association 2018;41(4):155-162
Purpose: In this study, we performed a longitudinal examination of the occurrence of homeboundness among community-dwelling elderly individuals and changes in associated factors, including the sense of coherence (SOC).Methods: A questionnaire survey was conducted targeting community-dwelling elderly individuals to evaluate homebound status, a basic checklist (CL), and SOC. Among these individuals, frail elderly people who maintained a non-homebound state were extracted and a follow-up survey was carried out one year later. Those who maintained the non-homebound state one year later were classified into the maintenance group and those who became socially withdrawn were classified into the transition group. Factors predicting the homebound state one year later were examined using multiple logistic regression analysis. Furthermore, the changes in CL and SOC between the transition and maintenance groups were compared.Results: In the transition group, motor function, cognitive function, and sense of manageability on the initial survey were significantly lower than those in the maintenance group. Significant correlations were noted in the homebound transition group with lack of money management (OR: 3.04, 95% CI: 1.19-7.82) and a declined sense of manageability (OR: 0.82, 95% CI: 0.69-0.99). Depression and the sense of manageability had also significantly deteriorated one year later compared with those in the maintenance group.Conclusion: This study suggests that individuals who transition to a state of homeboundness have a slightly lower SOC than those who maintain their non-homebound status.
2.Comparative Study of the Distal Transverse Arch of the Hand Between the Dominant and Non-Dominant Hands and By Age and Sex
Hideki SHIRAISHI ; Hiroshi YUINE
The Japanese Journal of Rehabilitation Medicine 2023;60(11):974-982
Introduction:The range of motion (ROM) of the distal transverse arch of the hand has not been established and cleared sufficiently.Purpose:The aim of this study was to clarify the differences in the distal transverse arch of the hand in ROM between the dominant and non-dominant hands and by sex and age.Participants:We enrolled 118 healthy participants aged 20-69 years.Results:The average active and passive ROMs of the distal transverse arch of the hand were 135.4° ± 10.3°/168.9° ± 12.1° on the dominant side and 131.8° ± 9.8°/166.9° ± 13.2° on the non-dominant side. Active and passive ROMs were significantly larger on the dominant side than on the non-dominant side (p<0.001, p=0.009). The active or passive ROM of the distal transverse arch of the hand on either side did not differ significantly between men and women. However, the ROM of the ring finger component was significantly larger in women than in men on both sides (p=0.02~0.003). The active and passive ROMs of the distal transverse arch in both hands were significantly smaller in participants aged over 60 years than in those aged up to 60 years (p<0.05). Moreover, compared to participants in their 20s, participants in their 30s and 40s showed lower passive ROMs of the dominant hand and little finger component of the transversal arch in both hands (p<0.05).Discussion:Our results suggested that handedness, sex, and age should be considered when managing the distal transverse arch of the hand.
3.Comparative Study of the Distal Transverse Arch of the Hand Between the Dominant and Non-Dominant Hands and By Age and Sex
Hideki SHIRAISHI ; Hiroshi YUINE
The Japanese Journal of Rehabilitation Medicine 2023;():23013-
Introduction:The range of motion (ROM) of the distal transverse arch of the hand has not been established and cleared sufficiently.Purpose:The aim of this study was to clarify the differences in the distal transverse arch of the hand in ROM between the dominant and non-dominant hands and by sex and age.Participants:We enrolled 118 healthy participants aged 20-69 years.Results:The average active and passive ROMs of the distal transverse arch of the hand were 135.4° ± 10.3°/168.9° ± 12.1° on the dominant side and 131.8° ± 9.8°/166.9° ± 13.2° on the non-dominant side. Active and passive ROMs were significantly larger on the dominant side than on the non-dominant side (p<0.001, p=0.009). The active or passive ROM of the distal transverse arch of the hand on either side did not differ significantly between men and women. However, the ROM of the ring finger component was significantly larger in women than in men on both sides (p=0.02~0.003). The active and passive ROMs of the distal transverse arch in both hands were significantly smaller in participants aged over 60 years than in those aged up to 60 years (p<0.05). Moreover, compared to participants in their 20s, participants in their 30s and 40s showed lower passive ROMs of the dominant hand and little finger component of the transversal arch in both hands (p<0.05).Discussion:Our results suggested that handedness, sex, and age should be considered when managing the distal transverse arch of the hand.
4.Daily urinary excretion of bisphenol A.
Chikako ARAKAWA ; Kayumi FUJIMAKI ; Jun YOSHINAGA ; Hideki IMAI ; Shigeko SERIZAWA ; Hiroaki SHIRAISHI
Environmental Health and Preventive Medicine 2004;9(1):22-26
OBJECTIVESConcerns over dietary exposure to bisphenol A (BPA), an endocrine disruptor, have been raised because BPA is contained in resins and plastics commonly used for the preservation of food and beverages. The purpose of the present study was to assess daily intake levels of BPA in a group of male subjects by measuring total urinary BPA (free BPA plus BPA released by treatment with β-glucuronidase), as well as determining intra-individual variation in BPA excretion.
METHODSTwenty-four-hour urine was collected from 5 subjects for 5 consecutive days for the evaluation of between-day variation in urinary BPA excretion and from 36 male subjects for the estimation of the level of daily BPA intake. BPA in the urine samples was measured by GC/MS/MS following enzymatic hydrolysis of BPA glucuronate, solid phase extraction, and derivatization.
RESULTSA large between-day variation was found over 5 days for the daily excretion of urinary BPA in the 5 subjects. The daily excretion of urinary BPA was distributed log-normally in the 36 male subjects, with the median value being 1.2 μg/day (range: <0.21-14 μg/day), which was far below the Tolerable Daily Intake (0.01 mg/kg bw) recommended by a scientific committee in the European Commission in 2002. However, the maximum estimated intake per body weight (0.2 μg/kg/day) was only one order of magnitude lower than the reported lowest level for reproductive/behavioral effects in pregnant mice (2 μg/kg/day).
CONCLUSIONSMeasuring urinary BPA in urine is a suitable approach for estimating short-term BPA intake levels in individuals and/or estimating the average exposure level of populations. Urine analyses will be increasingly important in the human health risk assessment of BPA.
5.Narrow-band imaging with magnifying endoscopy for Peyer's patches is useful in predicting the recurrence of remissive patients with ulcerative colitis.
Satoshi HIYAMA ; Hideki IIJIMA ; Syoichiro KAWAI ; Akira MUKAI ; Eri SHIRAISHI ; Shuko IWATANI ; Toshio YAMAGUCHI ; Manabu ARAKI ; Yoshito HAYASHI ; Shinichiro SHINZAKI ; Tsunekazu MIZUSHIMA ; Masahiko TSUJII ; Tetsuo TAKEHARA
Intestinal Research 2016;14(4):314-321
BACKGROUND/AIMS: Peyer's patches (PPs) are aggregates of lymphoid follicles that are mainly located in the distal ileum; they play a major role in mucosal immunity. We recently reported that patients with ulcerative colitis (UC) have alterations in PPs that can be detected using narrow-band imaging with magnifying endoscopy (NBI-ME). However, the usefulness of NBI-ME in UC treatment as a whole is still unknown. METHODS: We collected NBI-ME images of PPs from 67 UC patients who had undergone ileocolonoscopy. We evaluated changes in the villi using the "villi index," which is based on three categories: irregular formation, hyperemia, and altered vascular network pattern. The patients were divided into two groups on the basis of villi index: low (L)- and high (H)-types. We then determined the correlation between morphological alteration of the PPs and various clinical characteristics. In 52 patients who were in clinical remission, we also analyzed the correlation between NBI-ME findings of PPs and clinical recurrence. RESULTS: The time to clinical recurrence was significantly shorter in remissive UC patients with H-type PPs than in those with L-type PPs (P<0.01). Moreover, PP alterations were not correlated with age, sex, disease duration, clinical activity, endoscopic score, or extent of disease involvement. Multivariate analysis revealed that the existence of H-type PPs was an independent risk factor for clinical recurrence (hazard ratio, 3.3; P<0.01). CONCLUSIONS: UC patients with morphological alterations in PPs were at high risk of clinical relapse. Therefore, to predict the clinical course of UC, it may be useful to evaluate NBI-ME images of PPs.
Colitis, Ulcerative*
;
Endoscopy*
;
Humans
;
Hyperemia
;
Ileum
;
Immunity, Mucosal
;
Multivariate Analysis
;
Peyer's Patches*
;
Recurrence*
;
Risk Factors
;
Ulcer*
6.Narrow-band imaging with magnifying endoscopy for Peyer's patches is useful in predicting the recurrence of remissive patients with ulcerative colitis.
Satoshi HIYAMA ; Hideki IIJIMA ; Syoichiro KAWAI ; Akira MUKAI ; Eri SHIRAISHI ; Shuko IWATANI ; Toshio YAMAGUCHI ; Manabu ARAKI ; Yoshito HAYASHI ; Shinichiro SHINZAKI ; Tsunekazu MIZUSHIMA ; Masahiko TSUJII ; Tetsuo TAKEHARA
Intestinal Research 2016;14(4):314-321
BACKGROUND/AIMS: Peyer's patches (PPs) are aggregates of lymphoid follicles that are mainly located in the distal ileum; they play a major role in mucosal immunity. We recently reported that patients with ulcerative colitis (UC) have alterations in PPs that can be detected using narrow-band imaging with magnifying endoscopy (NBI-ME). However, the usefulness of NBI-ME in UC treatment as a whole is still unknown. METHODS: We collected NBI-ME images of PPs from 67 UC patients who had undergone ileocolonoscopy. We evaluated changes in the villi using the "villi index," which is based on three categories: irregular formation, hyperemia, and altered vascular network pattern. The patients were divided into two groups on the basis of villi index: low (L)- and high (H)-types. We then determined the correlation between morphological alteration of the PPs and various clinical characteristics. In 52 patients who were in clinical remission, we also analyzed the correlation between NBI-ME findings of PPs and clinical recurrence. RESULTS: The time to clinical recurrence was significantly shorter in remissive UC patients with H-type PPs than in those with L-type PPs (P<0.01). Moreover, PP alterations were not correlated with age, sex, disease duration, clinical activity, endoscopic score, or extent of disease involvement. Multivariate analysis revealed that the existence of H-type PPs was an independent risk factor for clinical recurrence (hazard ratio, 3.3; P<0.01). CONCLUSIONS: UC patients with morphological alterations in PPs were at high risk of clinical relapse. Therefore, to predict the clinical course of UC, it may be useful to evaluate NBI-ME images of PPs.
Colitis, Ulcerative*
;
Endoscopy*
;
Humans
;
Hyperemia
;
Ileum
;
Immunity, Mucosal
;
Multivariate Analysis
;
Peyer's Patches*
;
Recurrence*
;
Risk Factors
;
Ulcer*
7.Reliability, Validity, and Responsiveness of the Upper Extremity Test for Spinal Cord Injury
Kazumasa JIMBO ; Hideki SHIRAISHI ; Kazuhiro MIYATA ; Hiroshi YUINE ; Kousuke TAKAHAMA ; Tomohiro YOSHIMURA ; Shunnosuke OKA ; Mari KAKEHI ; Naho MURAKAMI ; Taichi YASUMORI ; Naohisa KIKUCHI
The Japanese Journal of Rehabilitation Medicine 2023;60(1):58-69
Introduction:There are few detailed evaluations of upper extremity function in Japan, especially for cervical spinal cord injury (CSCI). The capabilities of upper extremity test (CUE-T) evaluates upper extremity function, is specialized for CSCI, and is internationally used;however, there are few reports from Japan. This study verified the reliability, validity, and responsiveness of the CUE-T in Japan.Methods:We determined the interrater reliability, internal consistency, weighted kappa coefficient, intraclass correlation coefficient, and Cronbach's α coefficient for acute and chronic CSCI. The correlation coefficient with other evaluations was calculated and validated. Furthermore, the evaluation was performed twice at regular intervals, and the correlation between the change in CUE-T and other evaluations and the sensitivity to change using the standardized response mean (SRM) were verified.Results:The weighted kappa coefficient was 0.61-1.00, intraclass correlation coefficient was ≥0.9, and Cronbach's α coefficient were ≥0.9. The CUE-T and other evaluation methods showed moderate to strong correlations. In addition, the amount of change between CUE-T and the other evaluations were significantly correlated, and the SRM was ≥0.8.Discussion:In Japan, the CUE-T has been suggested to have good reliability, validity, responsiveness, and interpretability as an evaluation of upper extremity function in patients with CSCI. We will continue to verify the interpretability of the CUE-T and consider its dissemination in Japan.
8.Reliability, Validity, and Responsiveness of the Upper Extremity Test for Spinal Cord Injury
Kazumasa JIMBO ; Hideki SHIRAISHI ; Kazuhiro MIYATA ; Hiroshi YUINE ; Kousuke TAKAHAMA ; Tomohiro YOSHIMURA ; Shunnosuke OKA ; Mari KAKEHI ; Naho MURAKAMI ; Taichi YASUMORI ; Naohisa KIKUCHI
The Japanese Journal of Rehabilitation Medicine 2023;():22035-
Introduction:There are few detailed evaluations of upper extremity function in Japan, especially for cervical spinal cord injury (CSCI). The capabilities of upper extremity test (CUE-T) evaluates upper extremity function, is specialized for CSCI, and is internationally used;however, there are few reports from Japan. This study verified the reliability, validity, and responsiveness of the CUE-T in Japan.Methods:We determined the interrater reliability, internal consistency, weighted kappa coefficient, intraclass correlation coefficient, and Cronbach's α coefficient for acute and chronic CSCI. The correlation coefficient with other evaluations was calculated and validated. Furthermore, the evaluation was performed twice at regular intervals, and the correlation between the change in CUE-T and other evaluations and the sensitivity to change using the standardized response mean (SRM) were verified.Results:The weighted kappa coefficient was 0.61-1.00, intraclass correlation coefficient was ≥0.9, and Cronbach's α coefficient were ≥0.9. The CUE-T and other evaluation methods showed moderate to strong correlations. In addition, the amount of change between CUE-T and the other evaluations were significantly correlated, and the SRM was ≥0.8.Discussion:In Japan, the CUE-T has been suggested to have good reliability, validity, responsiveness, and interpretability as an evaluation of upper extremity function in patients with CSCI. We will continue to verify the interpretability of the CUE-T and consider its dissemination in Japan.